메뉴 건너뛰기




Volumn 2, Issue 2, 2010, Pages

Non-coding RNAs: A key to future personalized molecular therapy?

Author keywords

[No Author keywords available]

Indexed keywords

ANTI MIRNA OLIGONUCLEOTIDE; ANTINEOPLASTIC AGENT; CYCLIN D1; EXPORTIN 5; LOCKED NUCLEIC ACID ANTI MIRNA OLIGONUCLEOTIDE; MICRORNA; MICRORNA 100; MICRORNA 127; MICRORNA 143; MICRORNA 145; MICRORNA 147; MICRORNA 150; MICRORNA 154; MICRORNA 155; MICRORNA 15A; MICRORNA 16; MICRORNA 203; MICRORNA 221; MICRORNA 222; MICRORNA 323; MICRORNA 368; MICRORNA 370; MICRORNA 92; MYC PROTEIN; OLIGONUCLEOTIDE; PROTEIN BCL 2; RNA POLYMERASE II; UNCLASSIFIED DRUG; UNINDEXED DRUG; UNTRANSLATED RNA; WNT3A PROTEIN;

EID: 77955013582     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/gm133     Document Type: Review
Times cited : (105)

References (94)
  • 2
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?.
    • 10.1038/nrg2290, 18197166
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat Rev Genet 2008, 9:102-114. 10.1038/nrg2290, 18197166.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 3
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.
    • 10.1016/0092-8674(93)90529-Y, 8252621
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854. 10.1016/0092-8674(93)90529-Y, 8252621.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 4
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: understanding the structure and function of small RNAs.
    • 10.1038/nrm2085, 17183358
    • Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 2007, 8:23-36. 10.1038/nrm2085, 17183358.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 5
    • 34249810892 scopus 로고    scopus 로고
    • Argonaute proteins: mediators of RNA silencing.
    • 10.1016/j.molcel.2007.05.001, 17560368
    • Peters L, Meister G. Argonaute proteins: mediators of RNA silencing. Mol Cell 2007, 26:611-623. 10.1016/j.molcel.2007.05.001, 17560368.
    • (2007) Mol Cell , vol.26 , pp. 611-623
    • Peters, L.1    Meister, G.2
  • 6
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression.
    • 10.1101/gad.1184404, 374233, 15014042
    • Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev 2004, 18:504-511. 10.1101/gad.1184404, 374233, 15014042.
    • (2004) Genes Dev , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 7
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila.
    • 10.1016/j.cell.2007.01.043, 17346786
    • Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 2007, 128:1089-1103. 10.1016/j.cell.2007.01.043, 17346786.
    • (2007) Cell , vol.128 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3    Dus, M.4    Kellis, M.5    Sachidanandam, R.6    Hannon, G.J.7
  • 9
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome.
    • 10.1016/j.cell.2009.01.045, 2792755, 19239887
    • Malone CD, Hannon GJ. Small RNAs as guardians of the genome. Cell 2009, 136:656-668. 10.1016/j.cell.2009.01.045, 2792755, 19239887.
    • (2009) Cell , vol.136 , pp. 656-668
    • Malone, C.D.1    Hannon, G.J.2
  • 10
    • 38049155825 scopus 로고    scopus 로고
    • Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA.
    • 10.1038/nature06468, 2743558, 18185590
    • Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, Cui H. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008, 451:202-206. 10.1038/nature06468, 2743558, 18185590.
    • (2008) Nature , vol.451 , pp. 202-206
    • Yu, W.1    Gius, D.2    Onyango, P.3    Muldoon-Jacobs, K.4    Karp, J.5    Feinberg, A.P.6    Cui, H.7
  • 12
    • 0037133942 scopus 로고    scopus 로고
    • Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions.
    • 10.1016/S0092-8674(02)00718-3, 12007400
    • Kiss T. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. Cell 2002, 109:145-148. 10.1016/S0092-8674(02)00718-3, 12007400.
    • (2002) Cell , vol.109 , pp. 145-148
    • Kiss, T.1
  • 13
    • 0036703184 scopus 로고    scopus 로고
    • The expanding snoRNA world.
    • 10.1016/S0300-9084(02)01402-5, 12457565
    • Bachellerie JP, Cavaille J, Huttenhofer A. The expanding snoRNA world. Biochimie 2002, 84:775-790. 10.1016/S0300-9084(02)01402-5, 12457565.
    • (2002) Biochimie , vol.84 , pp. 775-790
    • Bachellerie, J.P.1    Cavaille, J.2    Huttenhofer, A.3
  • 14
    • 33846932045 scopus 로고    scopus 로고
    • Genome-wide analyses of retrogenes derived from the human box H/ACA snoRNAs.
    • 1802619, 17175533
    • Luo Y, Li S. Genome-wide analyses of retrogenes derived from the human box H/ACA snoRNAs. Nucleic Acids Res 2007, 35:559-571. 1802619, 17175533.
    • (2007) Nucleic Acids Res , vol.35 , pp. 559-571
    • Luo, Y.1    Li, S.2
  • 16
    • 68449095847 scopus 로고    scopus 로고
    • Evolution, biogenesis and function of promoter-associated RNAs.
    • Taft RJ, Kaplan CD, Simons C, Mattick JS. Evolution, biogenesis and function of promoter-associated RNAs. Cell Cycle 2009, 8:2332-2338.
    • (2009) Cell Cycle , vol.8 , pp. 2332-2338
    • Taft, R.J.1    Kaplan, C.D.2    Simons, C.3    Mattick, J.S.4
  • 17
    • 67649382485 scopus 로고    scopus 로고
    • Dicer independent small RNAs associate with telomeric heterochromatin.
    • 10.1261/rna.1423309, 2704082, 19460867
    • Cao F, Li X, Hiew S, Brady H, Liu Y, Dou Y. Dicer independent small RNAs associate with telomeric heterochromatin. RNA 2009, 15:1274-1281. 10.1261/rna.1423309, 2704082, 19460867.
    • (2009) RNA , vol.15 , pp. 1274-1281
    • Cao, F.1    Li, X.2    Hiew, S.3    Brady, H.4    Liu, Y.5    Dou, Y.6
  • 19
    • 56949096813 scopus 로고    scopus 로고
    • Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications.
    • 10.1007/s00335-008-9119-8, 18636290
    • Rossi S, Sevignani C, Nnadi SC, Siracusa LD, Calin GA. Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications. Mamm Genome 2008, 19:526-540. 10.1007/s00335-008-9119-8, 18636290.
    • (2008) Mamm Genome , vol.19 , pp. 526-540
    • Rossi, S.1    Sevignani, C.2    Nnadi, S.C.3    Siracusa, L.D.4    Calin, G.A.5
  • 20
    • 30844442607 scopus 로고    scopus 로고
    • The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C.
    • 10.1126/science.1118265, 16357227
    • Kishore S, Stamm S. The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C. Science 2006, 311:230-232. 10.1126/science.1118265, 16357227.
    • (2006) Science , vol.311 , pp. 230-232
    • Kishore, S.1    Stamm, S.2
  • 21
    • 45849144806 scopus 로고    scopus 로고
    • SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in mice.
    • 10.1371/journal.pone.0001709, 2248623, 18320030
    • Ding F, Li HH, Zhang S, Solomon NM, Camper SA, Cohen P, Francke U. SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in mice. PLoS ONE 2008, 3:e1709. 10.1371/journal.pone.0001709, 2248623, 18320030.
    • (2008) PLoS ONE , vol.3
    • Ding, F.1    Li, H.H.2    Zhang, S.3    Solomon, N.M.4    Camper, S.A.5    Cohen, P.6    Francke, U.7
  • 23
    • 68349143121 scopus 로고    scopus 로고
    • Implication of snoRNA U50 in human breast cancer.
    • 10.1016/S1673-8527(08)60134-4, 2854654, 19683667
    • Dong XY, Guo P, Boyd J, Sun X, Li Q, Zhou W, Dong JT. Implication of snoRNA U50 in human breast cancer. J Genet Genomics 2009, 36:447-454. 10.1016/S1673-8527(08)60134-4, 2854654, 19683667.
    • (2009) J Genet Genomics , vol.36 , pp. 447-454
    • Dong, X.Y.1    Guo, P.2    Boyd, J.3    Sun, X.4    Li, Q.5    Zhou, W.6    Dong, J.T.7
  • 26
    • 33947305594 scopus 로고    scopus 로고
    • Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay.
    • 10.1101/gad.1525507, 1820944, 17369403
    • Ni JZ, Grate L, Donohue JP, Preston C, Nobida N, O'Brien G, Shiue L, Clark TA, Blume JE, Ares M. Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. Genes Dev 2007, 21:708-718. 10.1101/gad.1525507, 1820944, 17369403.
    • (2007) Genes Dev , vol.21 , pp. 708-718
    • Ni, J.Z.1    Grate, L.2    Donohue, J.P.3    Preston, C.4    Nobida, N.5    O'Brien, G.6    Shiue, L.7    Clark, T.A.8    Blume, J.E.9    Ares, M.10
  • 32
    • 65249180150 scopus 로고    scopus 로고
    • SnapShot: microRNAs in cancer.
    • 10.1016/j.cell.2009.04.040, 19410551
    • Spizzo R, Nicoloso MS, Croce CM, Calin GA. SnapShot: microRNAs in cancer. Cell 2009, 137:586-586.e1. 10.1016/j.cell.2009.04.040, 19410551.
    • (2009) Cell , vol.137
    • Spizzo, R.1    Nicoloso, M.S.2    Croce, C.M.3    Calin, G.A.4
  • 37
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis.
    • 10.1038/cr.2008.24, 18270520
    • Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008, 18:350-359. 10.1038/cr.2008.24, 18270520.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 41
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma.
    • 10.1038/sj.onc.1210228, 17237814
    • Szafranska AE, Davison TS, John J, Cannon T, Sipos B, Maghnouj A, Labourier E, Hahn SA. MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 2007, 26:4442-4452. 10.1038/sj.onc.1210228, 17237814.
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3    Cannon, T.4    Sipos, B.5    Maghnouj, A.6    Labourier, E.7    Hahn, S.A.8
  • 42
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
    • 10.1001/jama.297.17.1901, 17473300
    • Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, Liu CG, Bhatt D, Taccioli C, Croce CM. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007, 297:1901-1908. 10.1001/jama.297.17.1901, 17473300.
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3    Volinia, S.4    Alder, H.5    Hagan, J.P.6    Liu, C.G.7    Bhatt, D.8    Taccioli, C.9    Croce, C.M.10
  • 44
    • 33646157967 scopus 로고    scopus 로고
    • Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.
    • 10.1038/sj.onc.1209283, 16331254
    • Murakami Y, Yasuda T, Saigo K, Urashima T, Toyoda H, Okanoue T, Shimotohno K. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 2006, 25:2537-2545. 10.1038/sj.onc.1209283, 16331254.
    • (2006) Oncogene , vol.25 , pp. 2537-2545
    • Murakami, Y.1    Yasuda, T.2    Saigo, K.3    Urashima, T.4    Toyoda, H.5    Okanoue, T.6    Shimotohno, K.7
  • 45
    • 67651056195 scopus 로고    scopus 로고
    • MicroRNA expression profiles in thyroid tumors.
    • 10.1007/s12022-009-9069-z, 19352602
    • Nikiforova MN, Chiosea SI, Nikiforov YE. MicroRNA expression profiles in thyroid tumors. Endocr Pathol 2009, 20:85-91. 10.1007/s12022-009-9069-z, 19352602.
    • (2009) Endocr Pathol , vol.20 , pp. 85-91
    • Nikiforova, M.N.1    Chiosea, S.I.2    Nikiforov, Y.E.3
  • 47
    • 58849148000 scopus 로고    scopus 로고
    • MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes.
    • 10.1182/blood-2008-07-163907, 18941111
    • Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N, Sawada K. MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009, 113:396-402. 10.1182/blood-2008-07-163907, 18941111.
    • (2009) Blood , vol.113 , pp. 396-402
    • Inomata, M.1    Tagawa, H.2    Guo, Y.M.3    Kameoka, Y.4    Takahashi, N.5    Sawada, K.6
  • 49
    • 14844354250 scopus 로고    scopus 로고
    • Accumulation of miR-155 and BIC RNA in human B cell lymphomas.
    • 10.1073/pnas.0500613102, 552785,552785, 15738415
    • Eis PS, Tam W, Sun L, Chadburn A, Li Z, Gomez MF, Lund E, Dahlberg JE. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 2005, 102:3627-3632. 10.1073/pnas.0500613102, 552785,552785, 15738415.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3627-3632
    • Eis, P.S.1    Tam, W.2    Sun, L.3    Chadburn, A.4    Li, Z.5    Gomez, M.F.6    Lund, E.7    Dahlberg, J.E.8
  • 50
    • 73349136775 scopus 로고    scopus 로고
    • MiR-155: on the crosstalk between inflammation and cancer.
    • 10.1080/08830180903093796, 19811312
    • Tili E, Croce CM, Michaille JJ. miR-155: on the crosstalk between inflammation and cancer. Int Rev Immunol 2009, 28:264-284. 10.1080/08830180903093796, 19811312.
    • (2009) Int Rev Immunol , vol.28 , pp. 264-284
    • Tili, E.1    Croce, C.M.2    Michaille, J.J.3
  • 51
    • 66749164641 scopus 로고    scopus 로고
    • A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers.
    • 10.1093/carcin/bgp099, 2691138, 19380522
    • Christensen BC, Moyer BJ, Avissar M, Ouellet LG, Plaza SL, McClean MD, Marsit CJ, Kelsey KT. A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers. Carcinogenesis 2009, 30:1003-1007. 10.1093/carcin/bgp099, 2691138, 19380522.
    • (2009) Carcinogenesis , vol.30 , pp. 1003-1007
    • Christensen, B.C.1    Moyer, B.J.2    Avissar, M.3    Ouellet, L.G.4    Plaza, S.L.5    McClean, M.D.6    Marsit, C.J.7    Kelsey, K.T.8
  • 54
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
    • 10.1038/nature06174, 17898713
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449:682-688. 10.1038/nature06174, 17898713.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 57
    • 70349454207 scopus 로고    scopus 로고
    • Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.
    • 10.1158/1078-0432.CCR-09-0627, 2745503, 19737943
    • Schetter AJ, Nguyen GH, Bowman ED, Mathe EA, Yuen ST, Hawkes JE, Croce CM, Leung SY, Harris CC. Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. Clin Cancer Res 2009, 15:5878-5887. 10.1158/1078-0432.CCR-09-0627, 2745503, 19737943.
    • (2009) Clin Cancer Res , vol.15 , pp. 5878-5887
    • Schetter, A.J.1    Nguyen, G.H.2    Bowman, E.D.3    Mathe, E.A.4    Yuen, S.T.5    Hawkes, J.E.6    Croce, C.M.7    Leung, S.Y.8    Harris, C.C.9
  • 58
    • 65849322883 scopus 로고    scopus 로고
    • Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients.
    • 10.1371/journal.pone.0005532, 2678255, 19440243
    • Tanaka M, Oikawa K, Takanashi M, Kudo M, Ohyashiki J, Ohyashiki K, Kuroda M. Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients. PLoS ONE 2009, 4:e5532. 10.1371/journal.pone.0005532, 2678255, 19440243.
    • (2009) PLoS ONE , vol.4
    • Tanaka, M.1    Oikawa, K.2    Takanashi, M.3    Kudo, M.4    Ohyashiki, J.5    Ohyashiki, K.6    Kuroda, M.7
  • 59
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening.
    • 10.1136/gut.2008.167817, 19201770
    • Ng EK, Chong WW, Jin H, Lam EK, Shin VY, Yu J, Poon TC, Ng SS, Sung JJ. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009, 58:1375-1381. 10.1136/gut.2008.167817, 19201770.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3    Lam, E.K.4    Shin, V.Y.5    Yu, J.6    Poon, T.C.7    Ng, S.S.8    Sung, J.J.9
  • 60
    • 70449709345 scopus 로고    scopus 로고
    • Plasma miR-208 as a biomarker of myocardial injury.
    • 10.1373/clinchem.2009.125310, 19696117
    • Ji X, Takahashi R, Hiura Y, Hirokawa G, Fukushima Y, Iwai N. Plasma miR-208 as a biomarker of myocardial injury. Clin Chem 2009, 55:1944-1949. 10.1373/clinchem.2009.125310, 19696117.
    • (2009) Clin Chem , vol.55 , pp. 1944-1949
    • Ji, X.1    Takahashi, R.2    Hiura, Y.3    Hirokawa, G.4    Fukushima, Y.5    Iwai, N.6
  • 61
    • 2342427578 scopus 로고    scopus 로고
    • Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.
    • 10.1074/jbc.M311683200, 14960586
    • Wu H, Lima WF, Zhang H, Fan A, Sun H, Crooke ST. Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs. J Biol Chem 2004, 279:17181-17189. 10.1074/jbc.M311683200, 14960586.
    • (2004) J Biol Chem , vol.279 , pp. 17181-17189
    • Wu, H.1    Lima, W.F.2    Zhang, H.3    Fan, A.4    Sun, H.5    Crooke, S.T.6
  • 64
    • 33751264968 scopus 로고    scopus 로고
    • Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells.
    • 10.1158/1078-0432.CCR-06-0588, 17085671
    • Tsuda N, Ishiyama S, Li Y, Ioannides CG, Abbruzzese JL, Chang DZ. Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. Clin Cancer Res 2006, 12:6557-6564. 10.1158/1078-0432.CCR-06-0588, 17085671.
    • (2006) Clin Cancer Res , vol.12 , pp. 6557-6564
    • Tsuda, N.1    Ishiyama, S.2    Li, Y.3    Ioannides, C.G.4    Abbruzzese, J.L.5    Chang, D.Z.6
  • 65
    • 64549085589 scopus 로고    scopus 로고
    • Synthetic microRNA targeting glioma-associated antigen-1 protein.
    • full_text, 19301660
    • Tsuda N, Mine T, Ioannides CG, Chang DZ. Synthetic microRNA targeting glioma-associated antigen-1 protein. Methods Mol Biol 2009, 487:435-449. full_text, 19301660.
    • (2009) Methods Mol Biol , vol.487 , pp. 435-449
    • Tsuda, N.1    Mine, T.2    Ioannides, C.G.3    Chang, D.Z.4
  • 66
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells.
    • 10.1038/nmeth1079, 17694064
    • Ebert MS, Neilson JR, Sharp PA. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 2007, 4:721-726. 10.1038/nmeth1079, 17694064.
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 67
  • 68
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha.
    • 10.1038/sj.emboj.7600491, 544904, 15565168
    • Zeng Y, Yi R, Cullen BR. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J 2005, 24:138-148. 10.1038/sj.emboj.7600491, 544904, 15565168.
    • (2005) EMBO J , vol.24 , pp. 138-148
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 69
    • 33747754760 scopus 로고    scopus 로고
    • Lessons from Nature: microRNA-based shRNA libraries.
    • 10.1038/nmeth923, 16929316
    • Chang K, Elledge SJ, Hannon GJ. Lessons from Nature: microRNA-based shRNA libraries. Nat Methods 2006, 3:707-714. 10.1038/nmeth923, 16929316.
    • (2006) Nat Methods , vol.3 , pp. 707-714
    • Chang, K.1    Elledge, S.J.2    Hannon, G.J.3
  • 71
    • 34250679056 scopus 로고    scopus 로고
    • Locked nucleic acid oligonucleotides: the next generation of antisense agents?.
    • 10.2165/00063030-200721040-00004, 17628121
    • Grunweller A, Hartmann RK. Locked nucleic acid oligonucleotides: the next generation of antisense agents?. BioDrugs 2007, 21:235-243. 10.2165/00063030-200721040-00004, 17628121.
    • (2007) BioDrugs , vol.21 , pp. 235-243
    • Grunweller, A.1    Hartmann, R.K.2
  • 72
    • 33646471662 scopus 로고    scopus 로고
    • Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
    • 10.1073/pnas.0602266103, 1459012, 16641092
    • Costinean S, Zanesi N, Pekarsky Y, Tili E, Volinia S, Heerema N, Croce CM. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci USA 2006, 103:7024-7029. 10.1073/pnas.0602266103, 1459012, 16641092.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7024-7029
    • Costinean, S.1    Zanesi, N.2    Pekarsky, Y.3    Tili, E.4    Volinia, S.5    Heerema, N.6    Croce, C.M.7
  • 73
    • 46749136860 scopus 로고    scopus 로고
    • MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas.
    • 10.2353/ajpath.2008.080009, 2438301, 18583325
    • Nie K, Gomez M, Landgraf P, Garcia JF, Liu Y, Tan LH, Chadburn A, Tuschl T, Knowles DM, Tam W. MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas. Am J Pathol 2008, 173:242-252. 10.2353/ajpath.2008.080009, 2438301, 18583325.
    • (2008) Am J Pathol , vol.173 , pp. 242-252
    • Nie, K.1    Gomez, M.2    Landgraf, P.3    Garcia, J.F.4    Liu, Y.5    Tan, L.H.6    Chadburn, A.7    Tuschl, T.8    Knowles, D.M.9    Tam, W.10
  • 74
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.
    • 10.1158/0008-5472.CAN-07-2462, 17942906
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007, 67:9762-9770. 10.1158/0008-5472.CAN-07-2462, 17942906.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6    Petrelli, N.J.7    Dunn, S.P.8    Krueger, L.J.9
  • 75
    • 35548995316 scopus 로고    scopus 로고
    • Downregulation of microRNAs-143 and -145 in B-cell malignancies.
    • 10.1111/j.1349-7006.2007.00618.x, 17892514
    • Akao Y, Nakagawa Y, Kitade Y, Kinoshita T, Naoe T. Downregulation of microRNAs-143 and -145 in B-cell malignancies. Cancer Sci 2007, 98:1914-1920. 10.1111/j.1349-7006.2007.00618.x, 17892514.
    • (2007) Cancer Sci , vol.98 , pp. 1914-1920
    • Akao, Y.1    Nakagawa, Y.2    Kitade, Y.3    Kinoshita, T.4    Naoe, T.5
  • 77
    • 48949119481 scopus 로고    scopus 로고
    • Breast cancer metastasis: a microRNA story.
    • 10.1186/bcr1867, 2397516, 18373886
    • Negrini M, Calin GA. Breast cancer metastasis: a microRNA story. Breast Cancer Res 2008, 10:203. 10.1186/bcr1867, 2397516, 18373886.
    • (2008) Breast Cancer Res , vol.10 , pp. 203
    • Negrini, M.1    Calin, G.A.2
  • 80
    • 50249103246 scopus 로고    scopus 로고
    • MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma.
    • 10.1038/modpathol.2008.105, 18587330
    • Chen YT, Kitabayashi N, Zhou XK, Fahey TJ, Scognamiglio T. MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod Pathol 2008, 21:1139-1146. 10.1038/modpathol.2008.105, 18587330.
    • (2008) Mod Pathol , vol.21 , pp. 1139-1146
    • Chen, Y.T.1    Kitabayashi, N.2    Zhou, X.K.3    Fahey, T.J.4    Scognamiglio, T.5
  • 82
    • 0034661474 scopus 로고    scopus 로고
    • Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation.
    • 10.1093/nar/28.14.2717, 102653, 10908328
    • Bijsterbosch MK, Rump ET, De Vrueh RL, Dorland R, van Veghel R, Tivel KL, Biessen EA, van Berkel TJ, Manoharan M. Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation. Nucleic Acids Res 2000, 28:2717-2725. 10.1093/nar/28.14.2717, 102653, 10908328.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2717-2725
    • Bijsterbosch, M.K.1    Rump, E.T.2    De Vrueh, R.L.3    Dorland, R.4    van Veghel, R.5    Tivel, K.L.6    Biessen, E.A.7    van Berkel, T.J.8    Manoharan, M.9
  • 83
    • 0036073335 scopus 로고    scopus 로고
    • Bis-Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides are highly selectively taken up by the liver.
    • 10.1124/jpet.302.2.619, 12130724
    • Bijsterbosch MK, Manoharan M, Dorland R, Van Veghel R, Biessen EA, Van Berkel TJ. bis-Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides are highly selectively taken up by the liver. J Pharmacol Exp Ther 2002, 302:619-626. 10.1124/jpet.302.2.619, 12130724.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 619-626
    • Bijsterbosch, M.K.1    Manoharan, M.2    Dorland, R.3    Van Veghel, R.4    Biessen, E.A.5    Van Berkel, T.J.6
  • 84
    • 0345354684 scopus 로고    scopus 로고
    • Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice.
    • 10.1016/S1097-2765(03)00088-1, 12667461
    • Cerritelli SM, Frolova EG, Feng C, Grinberg A, Love PE, Crouch RJ. Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice. Mol Cell 2003, 11:807-815. 10.1016/S1097-2765(03)00088-1, 12667461.
    • (2003) Mol Cell , vol.11 , pp. 807-815
    • Cerritelli, S.M.1    Frolova, E.G.2    Feng, C.3    Grinberg, A.4    Love, P.E.5    Crouch, R.J.6
  • 85
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells.
    • 10.1126/science.1068999, 11910072
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553. 10.1126/science.1068999, 11910072.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 86
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.
    • 10.1038/nbt0502-497, 11981564
    • Miyagishi M, Taira K. U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 2002, 20:497-500. 10.1038/nbt0502-497, 11981564.
    • (2002) Nat Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 89
    • 74149083873 scopus 로고    scopus 로고
    • Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.
    • 10.1038/mt.2009.207, 19738602
    • Takeshita F, Patrawala L, Osaki M, Takahashi RU, Yamamoto Y, Kosaka N, Kawamata M, Kelnar K, Bader AG, Brown D, Ochiya T. Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 2009, 18:181-187. 10.1038/mt.2009.207, 19738602.
    • (2009) Mol Ther , vol.18 , pp. 181-187
    • Takeshita, F.1    Patrawala, L.2    Osaki, M.3    Takahashi, R.U.4    Yamamoto, Y.5    Kosaka, N.6    Kawamata, M.7    Kelnar, K.8    Bader, A.G.9    Brown, D.10    Ochiya, T.11
  • 90
    • 66349137358 scopus 로고    scopus 로고
    • Inositol phosphatase SHIP1 is a primary target of miR-155.
    • 10.1073/pnas.0902636106, 2678424, 19359473
    • O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 2009, 106:7113-7118. 10.1073/pnas.0902636106, 2678424, 19359473.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7113-7118
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3    Baltimore, D.4
  • 91
    • 70349439320 scopus 로고    scopus 로고
    • MiR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses.
    • 10.1073/pnas.0901216106, 2747202, 19721002
    • Liu G, Friggeri A, Yang Y, Park YJ, Tsuruta Y, Abraham E. miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc Natl Acad Sci USA 2009, 106:15819-15824. 10.1073/pnas.0901216106, 2747202, 19721002.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15819-15824
    • Liu, G.1    Friggeri, A.2    Yang, Y.3    Park, Y.J.4    Tsuruta, Y.5    Abraham, E.6
  • 92
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas.
    • 10.1158/0008-5472.CAN-07-1045, 17908999
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 2007, 67:8994-9000. 10.1158/0008-5472.CAN-07-1045, 17908999.
    • (2007) Cancer Res , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 93
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells.
    • 10.1073/pnas.0707351104, 2000550, 17875987
    • Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci USA 2007, 104:15472-15477. 10.1073/pnas.0707351104, 2000550, 17875987.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.