메뉴 건너뛰기




Volumn 36, Issue 10, 2009, Pages 951-960

MicroRNAs and apoptosis: Implications in the molecular therapy of human disease

Author keywords

Apotosis; Microrna; Molecular therapy

Indexed keywords

ANTI MICRORNA OLIGONUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; CASPASE 9; EFFECTOR CASPASE; HEAD INVOLUTION DEFECTIVE PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; MESSENGER RNA; MICRORNA; MICRORNA MASKING ANTISENSE OLIGONUCLEOTIDE; NUCLEOTIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1; RAS PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 72049096984     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05245.x     Document Type: Review
Times cited : (68)

References (92)
  • 1
    • 0038613483 scopus 로고    scopus 로고
    • MiRNAs: Micro managers of programmed cell death
    • Baehrecke EH. miRNAs: Micro managers of programmed cell death. Curr. Biol. 2003; 13: R473-5.
    • (2003) Curr. Biol. , vol.13
    • Baehrecke, E.H.1
  • 2
    • 33645321647 scopus 로고    scopus 로고
    • MicroRNAs in cell proliferation, cell death, and tumorigenesis
    • Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br. J. Cancer 2006; 94: 776-780.
    • (2006) Br. J. Cancer , vol.94 , pp. 776-780
    • Hwang, H.W.1    Mendell, J.T.2
  • 3
    • 33749528151 scopus 로고    scopus 로고
    • MiRNAs and apoptosis: RNAs to die for
    • DOI 10.1038/sj.onc.1209912, PII 1209912
    • Jovanovic M, Hengartner MO. MiRNAs and apoptosis: RNAs to die for Oncogene 2006; 25: 6176-6187 (Pubitemid 44527848)
    • (2006) Oncogene , vol.25 , Issue.46 , pp. 6176-6187
    • Jovanovic, M.1    Hengartner, M.O.2
  • 4
    • 2942620391 scopus 로고    scopus 로고
    • Expanding roles for miRNAs and siRNAs in cell regulation
    • DOI 10.1016/j.ceb.2004.02.006, PII S0955067404000158
    • Nakahara K, Carthew RW. Expanding roles for miRNAs and siRNAs in cell regulation. Curr. Opin. Cell Biol 2004; 16: 127-133 (Pubitemid 38757288)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.2 , pp. 127-133
    • Nakahara, K.1    Carthew, R.W.2
  • 5
    • 7444243756 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of cell death
    • Xu P, Quo M, Hay BA. MicroRNAs and the regulation of cell death. Trends Genet. 2004; 20: 617-624.
    • (2004) Trends Genet. , vol.20 , pp. 617-624
    • Xu, P.1    Quo, M.2    Hay, B.A.3
  • 6
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-854 (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 9
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • DOI 10.1261/rna.7135204
    • Cai X, Hagedorn. CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004; 10: 1957-1966 (Pubitemid 39557833)
    • (2004) RNA , vol.10 , Issue.12 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 10
    • 33750126619 scopus 로고    scopus 로고
    • Molecular design and delivery of siRNA
    • Inoue A, Sawata SY, Taira K. Molecular design and delivery of siRNA. J. Drug Target. 2006; 14:448-455.
    • (2006) J. Drug Target. , vol.14 , pp. 448-455
    • Inoue, A.1    Sawata, S.Y.2    Taira, K.3
  • 11
    • 34250638746 scopus 로고    scopus 로고
    • SiRNAs in drug discovery. Target validation and beyond
    • Natt F. siRNAs in drug discovery. Target validation and beyond. Curr. Opin. Mol. Ther. 2007; 9:242-247.
    • (2007) Curr. Opin. Mol. Ther. , vol.9 , pp. 242-247
    • Natt, F.1
  • 12
    • 33847793202 scopus 로고    scopus 로고
    • Gene silencing by small regulatory RNAs in mammalian cells
    • Scherr M, Eder M. Gene silencing by small regulatory RNAs in mammalian cells. Cell Cycle 2007; 6: 444-449 (Pubitemid 46393448)
    • (2007) Cell Cycle , vol.6 , Issue.4 , pp. 444-449
    • Scherr, M.1    Eder, M.2
  • 14
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Bürge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Bürge, C.B.2    Bartel, D.P.3
  • 15
    • 34948873550 scopus 로고    scopus 로고
    • How do microRNAs regulate gene expression?
    • Jackson. RJ, Standart N. How do microRNAs regulate gene expression? Sci. STKE 2007; 23:243-249.
    • (2007) Sci. STKE , vol.23 , pp. 243-249
    • Jackson, R.J.1    Standart, N.2
  • 16
    • 34247364093 scopus 로고    scopus 로고
    • Mechanisms of microRNA-mediated gene regulation in animal cells
    • DOI 10.1016/j.tig.2007.02.011, PII S0168952507000728
    • Nilsen TW. Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet. 2007; 23: 243-249 (Pubitemid 46628981)
    • (2007) Trends in Genetics , vol.23 , Issue.5 , pp. 243-249
    • Nilsen, T.W.1
  • 17
    • 33846277696 scopus 로고    scopus 로고
    • Filipowicz W Repression of protein synthesis by miRNAs: How many mechanisms?
    • Pillai RS, Bhattacharyya SN, Filipowicz W Repression of protein synthesis by miRNAs: How many mechanisms? Trends Cell Biol. 2007; 17:118-126.
    • (2007) Trends Cell Biol. , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2
  • 18
    • 24644480213 scopus 로고    scopus 로고
    • Inhibition of translational initiation, by Let-7 MicroRNA in human, cells
    • Pillai RS, Bhattacharyya SN, Artus CG et al. Inhibition of translational initiation, by Let-7 MicroRNA in human, cells. Science 2005; 309: 1573-1576.
    • (2005) Science , vol.309 , pp. 1573-1576
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Artus, C.G.3
  • 20
    • 33748587841 scopus 로고    scopus 로고
    • A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes
    • DOI 10.1016/j.cell.2006.07.031, PII S0092867406010993
    • Miranda KC, Huynh T, Tay Y et al A. pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 2006; 126: 1203-1217 (Pubitemid 44380294)
    • (2006) Cell , vol.126 , Issue.6 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.-S.4    Tam, W.-L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 21
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambras V. The functions of animal microRNAs. Nature 2004; 431: 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambras, V.1
  • 22
    • 28044471565 scopus 로고    scopus 로고
    • MicroRNA functions in animal development and human disease
    • DOI 10.1242/dev.02073
    • Alvarez-Garcia I, Miska EA. MicroRNA functions in animal development and human disease. Development 2005; 132:4653-4662 (Pubitemid 41685276)
    • (2005) Development , vol.132 , Issue.21 , pp. 4653-4662
    • Alvarez-Garcia, I.1    Miska, E.A.2
  • 24
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • DOI 10.1158/0008-5472.CAN-05-0137
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Ret. 2005; 65: 6029-6033 (Pubitemid 40994386)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 25
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas
    • DOI 10.1158/0008-5472.CAN-07-1045
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res. 2007; 67: 8994-9000. (Pubitemid 47535880)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 27
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • DOI 10.1074/jbc.M611393200
    • Zhu S, Si ML, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPMl). J. Biol. Chem. 2007; 282: 14328-14336 (Pubitemid 47100416)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.19 , pp. 14328-14336
    • Zhu, S.1    Si, M.-L.2    Wu, H.3    Mo, Y.-Y.4
  • 28
    • 33746018653 scopus 로고    scopus 로고
    • Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript
    • DOI 10.1038/nature04836, PII NATURE04836
    • Gupta A, Gartner JJ, Sethupathy P, Hatzigeorgiou AG, Fraser NW. Anti-apoptotic function of a microRNA encoded by the HSV-I latencyassociated transcript. Nature 2006; 442: 82-85 (Pubitemid 44064213)
    • (2006) Nature , vol.442 , Issue.7098 , pp. 82-85
    • Gupta, A.1    Gartner, J.J.2    Sethupathy, P.3    Hatzigeorgiou, A.G.4    Fraser, N.W.5
  • 33
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 2007; 26: 745-752.
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3
  • 34
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • DOI 10.1038/sj.onc.1210293, PII 1210293
    • Welch C, Chen Y, Stallings RL. Micro.RNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 2007; 26: 5017-5022 (Pubitemid 47172643)
    • (2007) Oncogene , vol.26 , Issue.34 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 36
    • 34948829119 scopus 로고    scopus 로고
    • The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes
    • DOI 10.1242/jcs.010728
    • Xu C, Lu Y, Lin H et al. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis via targeting HSP60/HS.P70 and caspase-9 in cardiomyocytes. J. Cell Sci 2007; 120: 3045-3052 (Pubitemid 47517087)
    • (2007) Journal of Cell Science , vol.120 , Issue.17 , pp. 3045-3052
    • Xu, C.1    Lu, Y.2    Pan, Z.3    Chu, W.4    Luo, X.5    Lin, H.6    Xiao, J.7    Shan, H.8    Wang, Z.9    Yang, B.10
  • 37
    • 0242266963 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling
    • DOI 10.1161/01.RES.0000100665.67510.F5
    • Izumiya Y, Kim S, Izumi Y et al. Apoptosis signal-regulating kinase 1 plays a pivotal, role in angiotensin II-induced cardiac hypertrophy and remodeling. Circ. Res. 2003; 93: 874-883 (Pubitemid 37363062)
    • (2003) Circulation Research , vol.93 , Issue.9 , pp. 874-883
    • Izumiya, Y.1    Kim, S.2    Izumi, Y.3    Yoshida, K.4    Yoshiyama, M.5    Matsuzawa, A.6    Ichijo, H.7    Iwao, H.8
  • 38
    • 0032858327 scopus 로고    scopus 로고
    • Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats: Temporal regulation and spatial heterogeneity
    • Tea BS, Dam TV, Moreau P, Hamet P, de Blois D. Apoptosis during regression, of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation, and spatial heterogeneity. Hypertension 1999; 34: 229-235 (Pubitemid 29409220)
    • (1999) Hypertension , vol.34 , Issue.2 , pp. 229-235
    • Tea, B.-S.1    Dam, T.-V.2    Moreau, P.3    Hamet, P.4    Deblois, D.5
  • 43
    • 0035854746 scopus 로고    scopus 로고
    • Oxidative preconditioning and apoptosis in L-cells: Roles of protein kinase B and mitogen-activated protein kinases
    • DOI 10.1074/jbc.M011136200
    • Han. H, Wang H, Long H, Nattel S, Wang Z. Oxidative preconditioning and apoptosis in 1-cells. Roles of protein kinase B and mitogenactivated protein kinases. J. Biol. Chem. 2001; 276: 26357-26364 (Pubitemid 37412853)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.28 , pp. 26357-26364
    • Han, H.1    Wang, H.2    Long, H.3    Nattel, S.4    Wang, Z.5
  • 44
    • 2542450997 scopus 로고    scopus 로고
    • Cellular remodeling of apoptosis in response to transient oxidative insult in. rat ventricular cell line H9c2: A critical role of the mitochondria death pathway
    • Han H, Long H, Wang H et al. Cellular remodeling of apoptosis in response to transient oxidative insult in. rat ventricular cell line H9c2: A critical role of the mitochondria death pathway. Am. J. Physiol. Heart Circ. Physiol. 2004; 286: H2169-82.
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.286
    • Han, H.1    Long, H.2    Wang, H.3
  • 45
    • 42549116145 scopus 로고    scopus 로고
    • JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes
    • DOI 10.1159/000129389
    • Lu Y, Zhou J, Xu C et al AKT/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford lasting resistance to oxidative stress-induced apoptosis in cardiomyocytes. Cell Physiol. Biochem. 2008; 21: 305-314 (Pubitemid 351591422)
    • (2008) Cellular Physiology and Biochemistry , vol.21 , Issue.4 , pp. 305-314
    • Lu, Y.1    Zhou, J.2    Xu, C.3    Lin, H.4    Xiao, J.5    Wang, Z.6    Yang, B.7
  • 46
    • 0037203537 scopus 로고    scopus 로고
    • Apoptotic signaling pathways: Caspases and stressactivated protein, kinases
    • Cho S-G, Choi E-J. Apoptotic signaling pathways: Caspases and stressactivated protein, kinases. J. Biochem. Mol. Biol. 2002; 35: 24-27
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 24-27
    • Cho, S.-G.1    Choi, E.-J.2
  • 48
    • 11844307184 scopus 로고    scopus 로고
    • + channels in regulating tumor cell proliferation and apoptosis
    • + channels in regulating tumor cell proliferation and apoptosis. Pflügers Arch. 2004; 448: 274-286
    • (2004) Pflügers Arch. , vol.448 , pp. 274-286
    • Wang, Z.1
  • 50
    • 34247244657 scopus 로고    scopus 로고
    • The microRNA let-7a modulates interleukin-6-dependent STAT-3 survival signaling in malignant human cholangiocytes
    • DOI 10.1074/jbc.M607712200
    • Meng F, Henson. R, Wehbe-Janek H, Smith H, Ueno Y, Patel. T. The MicroRNA let-7a modulates interleukin-6-dependent STAT-3 survival signaling in malignant human cholangiocytes. J. Biol. Chem. 2007; 282: 8256-8264 (Pubitemid 47093612)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.11 , pp. 8256-8264
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Smith, H.4    Ueno, Y.5    Patel, T.6
  • 51
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • DOI 10.1161/CIRCRESAHA.106.141986
    • Ji. R, Cheng Y, Yue J et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ. Res. 2007; 100: 1579-1588 (Pubitemid 46897261)
    • (2007) Circulation Research , vol.100 , Issue.11 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 52
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3
  • 53
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell, death 4 (PDCD4) is an important functional target of the microRNA, miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell, death 4 (PDCD4) is an important functional target of the microRNA, miR-21 in breast cancer cells. J. Biol. Chem. 2007; 263:1026-1033
    • (2007) J. Biol. Chem. , vol.263 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 54
    • 20444479428 scopus 로고    scopus 로고
    • Mendell JT. c-Mycregulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Mycregulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-843
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4
  • 55
    • 34047267329 scopus 로고    scopus 로고
    • An E2F/miR-20a autoregulatory feedback loop
    • Sylvestre Y, Guire V, Querido E et al. An E2F/miR-20a autoregulatory feedback loop. J. Biol. Chem. 2007; 282: 2135-2143
    • (2007) J. Biol. Chem. , vol.282 , pp. 2135-2143
    • Sylvestre, Y.1    Guire, V.2    Querido, E.3
  • 56
    • 34548687035 scopus 로고    scopus 로고
    • Mir-29 regulates Mcl-1 protein expression and apoptosis
    • DOI 10.1038/sj.onc.1210436, PII 1210436
    • Mott JL, Kobayashi S, Bronk SF, Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007; 26: 6133-6140 (Pubitemid 47414372)
    • (2007) Oncogene , vol.26 , Issue.42 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 57
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res. 2006; 66:1277-1281
    • (2006) Cancer Res. , vol.66 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 58
    • 0035799352 scopus 로고    scopus 로고
    • Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation
    • Lin KM, Lin B, Lian IY, Mestril R, Scheffler I, Dillmann WH. Combined and individual mitochondrial HSP60 and HSPlO expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation, Circulation 2001; 103: 1787-1792 (Pubitemid 32291417)
    • (2001) Circulation , vol.103 , Issue.13 , pp. 1787-1792
    • Lin, K.M.1    Lin, B.2    Lian, I.Y.3    Mestril, R.4    Scheffler, I.E.5    Dillmann, W.H.6
  • 59
    • 0037129860 scopus 로고    scopus 로고
    • Cytosolic HSP60, apoptosis, and myocardial injury
    • Kirchhoff SR, Gupta S, Knowlton AA. Cytosolic HSP60, apoptosis, and myocardial injury. Circulation 2002; 105:2899-2904
    • (2002) Circulation , vol.105 , pp. 2899-2904
    • Kirchhoff, S.R.1    Gupta, S.2    Knowlton, A.A.3
  • 60
    • 0028932259 scopus 로고
    • Overexpression of the rat inducible 70 kDa heat shock, protein in a transgenic mouse increases the resistance of the heart to ischemic injury
    • Marber MS, Mestril R, Chi. SH, Sayen MR. Overexpression of the rat inducible 70 kDa heat shock, protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J. Clin. Invest. 1995; 95: 1446-1456
    • (1995) J. Clin. Invest. , vol.95 , pp. 1446-1456
    • Marber, M.S.1    Mestril, R.2    Chi, S.H.3    Sayen, M.R.4
  • 61
    • 0042330503 scopus 로고    scopus 로고
    • Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells
    • DOI 10.1016/S0022-2828(03)00229-3
    • Shan YX, Liu TJ, Su HF, Samsamshariat A, Mestril R, Wang PH. HsplO and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells. J. Mol. Cell. Cardiol. 2003; 35: 1135-1143 (Pubitemid 37083257)
    • (2003) Journal of Molecular and Cellular Cardiology , vol.35 , Issue.9 , pp. 1135-1143
    • Shan, Y.-X.1    Liu, T.-J.2    Su, H.-F.3    Samsamshariat, A.4    Mestril, R.5    Wang, P.H.6
  • 62
    • 0034862016 scopus 로고    scopus 로고
    • Heat shock proteins and cardiac protection
    • DOI 10.1016/S0008-6363(01)00354-6, PII S0008636301003546
    • Latchman DS. Heat shock proteins and cardiac protection. Cardiovasc. Res. 2001; 51: 637-646 (Pubitemid 32800706)
    • (2001) Cardiovascular Research , vol.51 , Issue.4 , pp. 637-646
    • Latchman, D.S.1
  • 63
    • 33747396191 scopus 로고    scopus 로고
    • Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition
    • DOI 10.1161/01.RES.0000237387.05259.a5, PII 0000301220060818000015
    • Han Y, Chen YS, Liu Z et al. Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition. Circ. Res. 2006; 99: 415-423 (Pubitemid 44253698)
    • (2006) Circulation Research , vol.99 , Issue.4 , pp. 415-423
    • Han, Y.1    Chen, Y.-S.2    Liu, Z.3    Bodyak, N.4    Rigor, D.5    Bisping, E.6    Pu, W.T.7    Kang, P.M.8
  • 65
    • 0033805442 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis
    • Kannan K, Jain SK. Oxidative stress and apoptosis. Pathophysiology 2000;7:153-163
    • (2000) Pathophysiology , vol.7 , pp. 153-163
    • Kannan, K.1    Jain, S.K.2
  • 66
    • 36749085252 scopus 로고    scopus 로고
    • Role played by BRCAl in transcriptional regulation in response to therapy
    • Murray MM, Mullan PB, Harkin DP. Role played by BRCAl in transcriptional regulation in response to therapy. Biochem. Soc. Trans. 2007; 35: 1342-1346
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1342-1346
    • Murray, M.M.1    Mullan, P.B.2    Harkin, D.P.3
  • 70
    • 33846045953 scopus 로고    scopus 로고
    • Principles of microRNA regulation of a human, cellular signaling network
    • Cui Q, Yu Z, Purisima E, Wang E. Principles of microRNA regulation of a human, cellular signaling network. Mol Systems Biol. 2006; 2:46-52.
    • (2006) Mol Systems Biol. , vol.2 , pp. 46-52
    • Cui, Q.1    Yu, Z.2    Purisima, E.3    Wang, E.4
  • 71
    • 33644988684 scopus 로고    scopus 로고
    • MicroRNA therapeutics: A new niche for antisense nucleic acids
    • Hammond SM. MicroRNA therapeutics: A new niche for antisense nucleic acids. Trends Mol. Med. 2006; 12: 99-101.
    • (2006) Trends Mol. Med. , vol.12 , pp. 99-101
    • Hammond, S.M.1
  • 72
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J, Rajewsky N, Braich R. et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005; 438: 685-689
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 73
    • 34347381752 scopus 로고    scopus 로고
    • Novel approaches for gene-specific interference via manipulating actions of microRNAs: Examination on the pacemaker channel genes HCN2 and HCN4
    • DOI 10.1002/jcp.21062
    • Xiao J, Yang B, Lin H, Lu Y, Luo X, Wang Z. Novel approaches for gene-specific interference via manipulating actions of microRNAs: Examination on the pacemaker channel genes HCN2 and HCN4. J. Cell. Physiol. 2007; 212: 285-292 (Pubitemid 47025616)
    • (2007) Journal of Cellular Physiology , vol.212 , Issue.2 , pp. 285-292
    • Xiao, J.1    Yang, B.2    Lin, H.3    Lu, Y.4    Luo, X.5    Wang, Z.6
  • 75
    • 0032970234 scopus 로고    scopus 로고
    • The HCN gene family: Molecular basis of the hyperpolarization-activated pacemaker channels
    • Santero B, Tibbs GR. The HCN gene family: Molecular basis of the hyperpolarization-activated pacemaker channels. Ann. N Y. Acad. Sci. 1999; 868: 741-764
    • (1999) Ann. N Y. Acad. Sci. , vol.868 , pp. 741-764
    • Santero, B.1    Tibbs, G.R.2
  • 77
    • 35348914716 scopus 로고    scopus 로고
    • Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430
    • Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 2007; 318:271-274
    • (2007) Science , vol.318 , pp. 271-274
    • Choi, W.Y.1    Giraldez, A.J.2    Schier, A.F.3
  • 78
    • 22744450757 scopus 로고    scopus 로고
    • Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents
    • DiFrancesco D. Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents. Curr. Med. Res. Opin. 2005; 21:1115-1122
    • (2005) Curr. Med. Res. Opin. , vol.21 , pp. 1115-1122
    • Difrancesco, D.1
  • 80
    • 33646027887 scopus 로고    scopus 로고
    • LNA-modified oligonucleotides mediate specific inhibition of microRNA function
    • Ørom UA, Kauppinen S, Lund AH. LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 2006; 372: 137-141
    • (2006) Gene , vol.372 , pp. 137-141
    • Ørom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 81
    • 34250777057 scopus 로고    scopus 로고
    • Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections
    • DOI 10.1038/nprot.2007.153, PII NPROT.2007.153
    • Obernosterer G, Martinez J, Alenius M. Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat. Protoc. 2007; 2: 1508-1514 (Pubitemid 46952329)
    • (2007) Nature Protocols , vol.2 , Issue.6 , pp. 1508-1514
    • Obernosterer, G.1    Martinez, J.2    Alenius, M.3
  • 82
    • 0347755643 scopus 로고    scopus 로고
    • The microRNA registry
    • Griffiths-Jones S. The microRNA registry. Nucleic Acids Res. 2004; 32 (Database issue): D109-11.
    • (2004) Nucleic Acids Res. , vol.32 DATABASE ISSUE
    • Griffiths-Jones, S.1
  • 84
    • 23144449159 scopus 로고    scopus 로고
    • Microlnspector: A web tool for detection of miRNA binding sites in an RNA sequence
    • Rusinov V, Baev V, Minkov IN, Tabler M. Microlnspector: A web tool for detection of miRNA binding sites in an RNA sequence. Nucleic Acids Res. 2005; 33 (Webserver issue): W696-700.
    • (2005) Nucleic Acids Res. , vol.33 , Issue.WEBSERVER ISSUE
    • Rusinov, V.1    Baev, V.2    Minkov, I.N.3    Tabler, M.4
  • 85
    • 33644873722 scopus 로고    scopus 로고
    • MiRNAMap: Genomic maps of microRNA genes and their target genes in mammalian genomes
    • Hsu PW, Huang HD, Hsu SD et al. miRNAMap: Genomic maps of microRNA genes and their target genes in mammalian genomes. Nucleic Acids Res. 2006; 34 (Database issue): D135-9.
    • (2006) Nucleic Acids Res. , vol.34 DATABASE ISSUE
    • Hsu, P.W.1    Huang, H.D.2    Hsu, S.D.3
  • 86
    • 4644237189 scopus 로고    scopus 로고
    • Fast and effective prediction of microRNA/target duplexes
    • DOI 10.1261/rna.5248604
    • Rehmsmeier M, Steffen P, Höchsmann M, Giegerich R. Fast and effective prediction, of microRNA/target duplexes. RNA 2004; 10: 1507-1517 (Pubitemid 39288185)
    • (2004) RNA , vol.10 , Issue.10 , pp. 1507-1517
    • Rehmsmeier, M.1    Steffen, P.2    Hochsmann, M.3    Giegerich, R.4
  • 87
    • 33747814183 scopus 로고    scopus 로고
    • ProMiRII, a web server for clustered, nonclustered, conserved, nonconserved miRNA prediction
    • Nam J, Kim JH, Kim SK, Zhang B-T. ProMiRII, a web server for clustered, nonclustered, conserved, nonconserved miRNA prediction. Nucleic Acids Res. 2006; 34 (Webserver issue): W455-8.
    • (2006) Nucleic Acids Res. , vol.34 , Issue.WEBSERVER ISSUE
    • Nam, J.1    Kim, J.H.2    Kim, S.K.3    Zhang, B.-T.4
  • 88
    • 31044444975 scopus 로고    scopus 로고
    • TarBase: A comprehensive database of experimentally supported animal microRNA targets
    • DOI 10.1261/rna.2239606
    • Sethupathy P, Corda B, Hatziegeorgiou AG. TarBase: A comprehensive database of experimentally supported animal microRNA targets. RNA 2006; 12:192-197 (Pubitemid 43121923).
    • (2006) RNA , vol.12 , Issue.2 , pp. 192-197
    • Sethupathy, P.1    Corda, B.2    Hatzigeorgiou, A.G.3
  • 91
    • 38849145861 scopus 로고    scopus 로고
    • Prediction of both conserved and nonconserved microRNA targets in animals
    • DOI 10.1093/bioinformatics/btm595
    • Wang X, El Naqa IM. Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics 2008; 24: 325-332 (Pubitemid 351189007)
    • (2008) Bioinformatics , vol.24 , Issue.3 , pp. 325-332
    • Wang, X.1    El Naqa, I.M.2
  • 92
    • 33749645474 scopus 로고    scopus 로고
    • Zhang B-T. miTarget: MicroRNA target-gene prediction using a support vector machine
    • Kim S-K, Nam J-W, Rhee J-K, Lee W-J, Zhang B-T. miTarget: MicroRNA target-gene prediction using a support vector machine. BMC Bioinformatics 2006; 7:411.
    • (2006) BMC Bioinformatics , vol.7 , pp. 411
    • Kim, S.-K.1    Nam, J.-W.2    Rhee, J.-K.3    Lee, W.-J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.