메뉴 건너뛰기




Volumn 18, Issue 10, 2015, Pages 1376-1385

Stress weakens prefrontal networks: Molecular insults to higher cognition

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CALCIUM; CATECHOLAMINE; CYCLIC AMP; DOPAMINE 1 RECEPTOR; GUANFACINE; POTASSIUM CHANNEL; PRAZOSIN; PROTEIN KINASE C;

EID: 84942436905     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4087     Document Type: Review
Times cited : (491)

References (150)
  • 1
    • 0028938076 scopus 로고
    • Cellular basis of working memory
    • Goldman-Rakic, P.S. Cellular basis of working memory. Neuron 14, 477-485 (1995)
    • (1995) Neuron , vol.14 , pp. 477-485
    • Goldman-Rakic, P.S.1
  • 2
    • 0040246220 scopus 로고    scopus 로고
    • The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans
    • Ongür, D. &Price, J.L. The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb. Cortex 10, 206-219 (2000)
    • (2000) Cereb. Cortex , vol.10 , pp. 206-219
    • Ongür, D.1    Price, J.L.2
  • 3
    • 84959493306 scopus 로고    scopus 로고
    • Ameliorating treatment-refractory depression with intranasal ketamine: Potential NMDA receptor actions in the pain circuitry representing mental anguish
    • 26 January
    • Opler, L.A., Opler, M.G. &Arnsten, A.F.T. Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish. CNS Spectr. doi:10.1017/S1092852914000686 (26 January 2015)
    • (2015) CNS Spectr
    • Opler, L.A.1    Opler, M.G.2    Arnsten, A.F.T.3
  • 4
    • 0032967531 scopus 로고    scopus 로고
    • The reduced neuropil hypothesis: A circuit based model of schizophrenia
    • Selemon, L.D. &Goldman-Rakic, P.S. The reduced neuropil hypothesis: a circuit based model of schizophrenia. Biol. Psychiatry 45, 17-25 (1999)
    • (1999) Biol. Psychiatry , vol.45 , pp. 17-25
    • Selemon, L.D.1    Goldman-Rakic, P.S.2
  • 5
    • 84918818374 scopus 로고    scopus 로고
    • Progressive reduction in cortical thickness as psychosis develops: A multisite longitudinal neuroimaging study of youth at elevated clinical risk
    • Cannon, T.D. et al. Progressive reduction in cortical thickness as psychosis develops: A multisite longitudinal neuroimaging study of youth at elevated clinical risk. Biol. Psychiatry 77, 147-157 (2015)
    • (2015) Biol. Psychiatry , vol.77 , pp. 147-157
    • Cannon, T.D.1
  • 6
    • 0037480114 scopus 로고    scopus 로고
    • Progressive degeneration of nonphosphorylated neurofilament protein-enriched pyramidal neurons predicts cognitive impairment in Alzheimer's disease: Stereologic analysis of prefrontal cortex area
    • Bussière, T. et al. Progressive degeneration of nonphosphorylated neurofilament protein-enriched pyramidal neurons predicts cognitive impairment in Alzheimer's disease: stereologic analysis of prefrontal cortex area. J. Comp. Neurol. 463, 281-302 (2003)
    • (2003) J. Comp. Neurol , vol.463 , pp. 281-302
    • Bussière, T.1
  • 7
    • 33644817037 scopus 로고    scopus 로고
    • Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: A cross-sectional study
    • Blumberg, H.P. et al. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol. Psychiatry 59, 611-618 (2006)
    • (2006) Biol. Psychiatry , vol.59 , pp. 611-618
    • Blumberg, H.P.1
  • 8
    • 84870667003 scopus 로고    scopus 로고
    • Gray matter correlates of posttraumatic stress disorder: A quantitative meta-analysis
    • Kühn, S. &Gallinat, J. Gray matter correlates of posttraumatic stress disorder: a quantitative meta-analysis. Biol. Psychiatry 73, 70-74 (2013)
    • (2013) Biol. Psychiatry , vol.73 , pp. 70-74
    • Kühn, S.1    Gallinat, J.2
  • 9
    • 30344476947 scopus 로고    scopus 로고
    • Specializations of the granular prefrontal cortex of primates: Implications for cognitive processing
    • Elston, G.N. et al. Specializations of the granular prefrontal cortex of primates: implications for cognitive processing. Anat. Rec. A Discov. Mol. Cell. Evol. Biol. 288, 26-35 (2006)
    • (2006) Anat. Rec. A Discov. Mol. Cell. Evol. Biol , vol.288 , pp. 26-35
    • Elston, G.N.1
  • 10
    • 84874286656 scopus 로고    scopus 로고
    • NMDA receptors subserve working memory persistent neuronal firing in dorsolateral prefrontal cortex
    • Wang, M. et al. NMDA receptors subserve working memory persistent neuronal firing In dorsolateral prefrontal cortex. Neuron 77, 736-749 (2013)
    • (2013) Neuron , vol.77 , pp. 736-749
    • Wang, M.1
  • 11
    • 84880344454 scopus 로고    scopus 로고
    • Nicotinic and alpha;7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
    • Yang, Y. et al. Nicotinic and alpha;7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. Proc. Natl. Acad. Sci. USA 110, 12078-12083 (2013)
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 12078-12083
    • Yang, Y.1
  • 12
    • 84938614616 scopus 로고    scopus 로고
    • Developmental expression patterns of GABAA receptor subunits in layer 3 and 5 pyramidal cells of monkey prefrontal cortex
    • Datta, D., Arion, D. &Lewis, D.A. Developmental expression patterns of GABAA receptor subunits in layer 3 and 5 pyramidal cells of monkey prefrontal cortex. Cereb. Cortex 25, 2295-2305 (2015)
    • (2015) Cereb. Cortex , vol.25 , pp. 2295-2305
    • Datta, D.1    Arion, D.2    Lewis, D.A.3
  • 13
    • 84867125875 scopus 로고    scopus 로고
    • Neuromodulation of thought: Flexibilities and vulnerabilities in prefrontal cortical network synapses
    • Arnsten, A.F.T., Wang, M. &Paspalas, C.D. Neuromodulation of thought: Flexibilities and vulnerabilities in prefrontal cortical network synapses. Neuron 76, 223-239 (2012)
    • (2012) Neuron , vol.76 , pp. 223-239
    • Arnsten, A.F.T.1    Wang, M.2    Paspalas, C.D.3
  • 14
    • 84897499934 scopus 로고    scopus 로고
    • CAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex
    • Carlyle, B.C. et al. cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. Proc. Natl. Acad. Sci. USA 111, 5036-5041 (2014)
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 5036-5041
    • Carlyle, B.C.1
  • 15
    • 84863276777 scopus 로고    scopus 로고
    • Lost in transition: Aging-related changes in executive control by the medial prefrontal cortex
    • Caetano, M.S. et al. Lost in transition: Aging-related changes in executive control by the medial prefrontal cortex. J. Neurosci. 32, 3765-3777 (2012)
    • (2012) J. Neurosci , vol.32 , pp. 3765-3777
    • Caetano, M.S.1
  • 16
    • 66249129704 scopus 로고    scopus 로고
    • Stress signaling pathways that impair prefrontal cortex structure and function
    • Arnsten, A.F.T. Stress signaling pathways that impair prefrontal cortex structure and function. Nat. Rev. Neurosci. 10, 410-422 (2009)
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 410-422
    • Arnsten, A.F.T.1
  • 17
    • 0001422526 scopus 로고
    • Behavioral consequences of adaptation to controllable and uncontrollable noise
    • Glass, D.C., Reim, B. &Singer, J.E. Behavioral consequences of adaptation to controllable and uncontrollable noise. J. Exp. Soc. Psychol. 7, 244-257 (1971)
    • (1971) J. Exp. Soc. Psychol , vol.7 , pp. 244-257
    • Glass, D.C.1    Reim, B.2    Singer, J.E.3
  • 18
    • 0021507304 scopus 로고
    • Effects of task-irrelevant cues and reinforcement delay on choice-escape learning following inescapable shock: Evidence for a deficit in selective attention
    • Minor, T.R., Jackson, R.L. &Maier, S.F. Effects of task-irrelevant cues and reinforcement delay on choice-escape learning following inescapable shock: evidence for a deficit in selective attention. J. Exp. Psychol. Anim. Behav. Process. 10, 543-556 (1984)
    • (1984) J. Exp. Psychol. Anim. Behav. Process , vol.10 , pp. 543-556
    • Minor, T.R.1    Jackson, R.L.2    Maier, S.F.3
  • 19
    • 0030033256 scopus 로고    scopus 로고
    • Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys
    • Murphy, B.L., Arnsten, A.F.T., Goldman-Rakic, P.S. &Roth, R.H. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc. Natl. Acad. Sci. USA 93, 1325-1329 (1996)
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1325-1329
    • Murphy, B.L.1    Arnsten, A.F.T.2    Goldman-Rakic, P.S.3    Roth, R.H.4
  • 20
    • 0031945083 scopus 로고    scopus 로고
    • Noise stress impairs prefrontal cortical cognitive function in monkeys: Evidence for a hyperdopaminergic mechanism
    • Arnsten, A.F.T. &Goldman-Rakic, P.S. Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch. Gen. Psychiatry 55, 362-368 (1998)
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 362-368
    • Arnsten, A.F.T.1    Goldman-Rakic, P.S.2
  • 21
    • 55149087247 scopus 로고    scopus 로고
    • Intra-amygdala anxiogenic drug infusion prior to retrieval biases rats towards the use of habit memory
    • Elliott, A.E. &Packard, M.G. Intra-amygdala anxiogenic drug infusion prior to retrieval biases rats towards the use of habit memory. Neurobiol. Learn. Mem. 90, 616-623 (2008)
    • (2008) Neurobiol. Learn. Mem , vol.90 , pp. 616-623
    • Elliott, A.E.1    Packard, M.G.2
  • 23
    • 0041410156 scopus 로고    scopus 로고
    • Site and time dependent effects of acute stress on hippocampal long-term potentiation in freely behaving rats
    • Yamada, K., McEwen, B.S. &Pavlides, C. Site and time dependent effects of acute stress on hippocampal long-term potentiation in freely behaving rats. Exp. Brain Res. 152, 52-59 (2003)
    • (2003) Exp. Brain Res , vol.152 , pp. 52-59
    • Yamada, K.1    McEwen, B.S.2    Pavlides, C.3
  • 24
    • 0029999315 scopus 로고    scopus 로고
    • Role of the amygdala in the coordination of behavioral, neuroendocrine and prefrontal cortical monoamine responses to psychological stress in the rat
    • Goldstein, L.E., Rasmusson, A.M., Bunney, S.B. &Roth, R.H. Role of the amygdala in the coordination of behavioral, neuroendocrine and prefrontal cortical monoamine responses to psychological stress in the rat. J. Neurosci. 16, 4787-4798 (1996)
    • (1996) J. Neurosci , vol.16 , pp. 4787-4798
    • Goldstein, L.E.1    Rasmusson, A.M.2    Bunney, S.B.3    Roth, R.H.4
  • 25
    • 0032510998 scopus 로고    scopus 로고
    • The biology of feeling frazzled
    • Arnsten, A.F.T. The biology of feeling frazzled. Science 280, 1711-1712 (1998)
    • (1998) Science , vol.280 , pp. 1711-1712
    • Arnsten, A.F.T.1
  • 26
    • 33646411282 scopus 로고    scopus 로고
    • The effects of sex and hormonal status on restraint-stress-induced working memory impairment
    • Shansky, R.M., Rubinow, K., Brennan, A. &Arnsten, A.F. The effects of sex and hormonal status on restraint-stress-induced working memory impairment. Behav. Brain Funct. 2, 8 (2006)
    • (2006) Behav. Brain Funct , vol.2 , pp. 8
    • Shansky, R.M.1    Rubinow, K.2    Brennan, A.3    Arnsten, A.F.4
  • 27
    • 85027919793 scopus 로고    scopus 로고
    • Impairments of spatial working memory and attention following acute psychosocial stress
    • Olver, J.S., Pinney, M., Maruff, P. &Norman, T.R. Impairments of spatial working memory and attention following acute psychosocial stress. Stress Health 31, 115-123 (2015)
    • (2015) Stress Health , vol.31 , pp. 115-123
    • Olver, J.S.1    Pinney, M.2    Maruff, P.3    Norman, T.R.4
  • 28
    • 0036593119 scopus 로고    scopus 로고
    • The stressed hippocampus, synaptic plasticity and lost memories
    • Kim, J.J. &Diamond, D.M. The stressed hippocampus, synaptic plasticity and lost memories. Nat. Rev. Neurosci. 3, 453-462 (2002)
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 453-462
    • Kim, J.J.1    Diamond, D.M.2
  • 29
    • 79960188563 scopus 로고    scopus 로고
    • Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse
    • Spyrka, J., Danielewicz, J. &Hess, G. Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse. Brain Res. Bull. 85, 363-367 (2011)
    • (2011) Brain Res. Bull , vol.85 , pp. 363-367
    • Spyrka, J.1    Danielewicz, J.2    Hess, G.3
  • 31
    • 67349098525 scopus 로고    scopus 로고
    • Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex
    • Qin, S., Hermans, E.J., van Marle, H.J.F., Lou, J. &Fernandez, G. Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex. Biol. Psychiatry 66, 25-32 (2009)
    • (2009) Biol. Psychiatry , vol.66 , pp. 25-32
    • Qin, S.1    Hermans, E.J.2    Van Marle, H.J.F.3    Lou, J.4    Fernandez, G.5
  • 32
    • 84864446489 scopus 로고    scopus 로고
    • The effect of moderate acute psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans
    • Qin, S. et al. The effect of moderate acute psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans. Front. Integr. Neurosci. 6, 16 (2012)
    • (2012) Front. Integr. Neurosci , vol.6 , pp. 16
    • Qin, S.1
  • 33
    • 84897400208 scopus 로고    scopus 로고
    • Working memory-related frontal theta activity is decreased under acute stress
    • Gärtner, M., Rohde-Liebenau, L., Grimm, S. &Bajbouj, M. Working memory-related frontal theta activity is decreased under acute stress. Psychoneuroendocrinology 43, 105-113 (2014)
    • (2014) Psychoneuroendocrinology , vol.43 , pp. 105-113
    • Gärtner, M.1    Rohde-Liebenau, L.2    Grimm, S.3    Bajbouj, M.4
  • 35
    • 0028172570 scopus 로고
    • Beta-adrenergic activation and memory for emotional events
    • Cahill, L., Prins, B., Weber, M. &McGaugh, J.L. Beta-adrenergic activation and memory for emotional events. Nature 371, 702-704 (1994)
    • (1994) Nature , vol.371 , pp. 702-704
    • Cahill, L.1    Prins, B.2    Weber, M.3    McGaugh, J.L.4
  • 37
    • 75549083020 scopus 로고    scopus 로고
    • Stressful and intrusive life events preceding first episode psychosis
    • Raune, D., Kuipers, E. &Bebbington, P. Stressful and intrusive life events preceding first episode psychosis. Epidemiol. Psichiatr. Soc. 18, 221-228 (2009)
    • (2009) Epidemiol. Psichiatr. Soc , vol.18 , pp. 221-228
    • Raune, D.1    Kuipers, E.2    Bebbington, P.3
  • 38
    • 0030918345 scopus 로고    scopus 로고
    • Stress reactivity in bipolar patients and its relation to prior history of disorder
    • Hammen, C. &Gitlin, M. Stress reactivity in bipolar patients and its relation to prior history of disorder. Am. J. Psychiatry 154, 856-857 (1997)
    • (1997) Am. J. Psychiatry , vol.154 , pp. 856-857
    • Hammen, C.1    Gitlin, M.2
  • 39
    • 0004878466 scopus 로고    scopus 로고
    • Cross-national epidemiology of major depression and bipolar disorder
    • Weissman, M.M. et al. Cross-national epidemiology of major depression and bipolar disorder. J. Am. Med. Assoc. 276, 293-299 (1996)
    • (1996) J. Am. Med. Assoc , vol.276 , pp. 293-299
    • Weissman, M.M.1
  • 40
    • 69949143121 scopus 로고    scopus 로고
    • The epidemiology of trauma, PTSD, and other posttrauma disorders
    • Breslau, N. The epidemiology of trauma, PTSD, and other posttrauma disorders. Trauma Violence Abuse 10, 198-210 (2009)
    • (2009) Trauma Violence Abuse , vol.10 , pp. 198-210
    • Breslau, N.1
  • 41
    • 3142552351 scopus 로고    scopus 로고
    • Estrogen mediates sex differences in stress-induced prefrontal cortex dysfunction
    • Shansky, R.M. et al. Estrogen mediates sex differences in stress-induced prefrontal cortex dysfunction. Mol. Psychiatry 9, 531-538 (2004)
    • (2004) Mol. Psychiatry , vol.9 , pp. 531-538
    • Shansky, R.M.1
  • 42
    • 0031962557 scopus 로고    scopus 로고
    • The influence of age and sex on the prevalence of depressive conditions: Report from the National Survey of Psychiatric Morbidity
    • Bebbington, P.E. et al. The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Psychol. Med. 28, 9-19 (1998)
    • (1998) Psychol. Med , vol.28 , pp. 9-19
    • Bebbington, P.E.1
  • 43
    • 84885354428 scopus 로고    scopus 로고
    • Common psychosocial stressors in middle-aged women related to longstanding distress and increased risk of Alzheimer's disease: A 38-year longitudinal population study
    • Johansson, L. et al. Common psychosocial stressors in middle-aged women related to longstanding distress and increased risk of Alzheimer's disease: a 38-year longitudinal population study. BMJ Open 3, e003142 (2013)
    • (2013) BMJ Open , vol.3 , pp. e003142
    • Johansson, L.1
  • 44
    • 33749528834 scopus 로고    scopus 로고
    • Chronic psychological distress and risk of Alzheimer's disease in old age
    • Wilson, R.S. et al. Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology 27, 143-153 (2006)
    • (2006) Neuroepidemiology , vol.27 , pp. 143-153
    • Wilson, R.S.1
  • 45
    • 0025672802 scopus 로고
    • The determinants of stress-induced activation of the prefrontal cortical dopamine system
    • Deutch, A.Y. &Roth, R.H. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog. Brain Res. 85, 367-402 (1990)
    • (1990) Prog. Brain Res , vol.85 , pp. 367-402
    • Deutch, A.Y.1    Roth, R.H.2
  • 46
    • 78649966665 scopus 로고    scopus 로고
    • Dopamine in motivational control: Rewarding, aversive, and alerting
    • Bromberg-Martin, E.S., Matsumoto, M. &Hikosaka, O. Dopamine in motivational control: rewarding, aversive, and alerting. Neuron 68, 815-834 (2010)
    • (2010) Neuron , vol.68 , pp. 815-834
    • Bromberg-Martin, E.S.1    Matsumoto, M.2    Hikosaka, O.3
  • 47
    • 84896445637 scopus 로고    scopus 로고
    • Higher dopamine release induced by less rather than more preferred reward during a working memory task in the primate prefrontal cortex
    • Kodama, T., Hikosaka, K., Honda, Y., Kojima, T. &Watanabe, M. Higher dopamine release induced by less rather than more preferred reward during a working memory task in the primate prefrontal cortex. Behav. Brain Res. 266, 104-107 (2014)
    • (2014) Behav. Brain Res , vol.266 , pp. 104-107
    • Kodama, T.1    Hikosaka, K.2    Honda, Y.3    Kojima, T.4    Watanabe, M.5
  • 48
    • 0031668878 scopus 로고    scopus 로고
    • Amygdaloid corticotropin-releasing factor targets locus coeruleus dendrites: Substrate for the co-ordination of emotional and cognitive limbs of the stress response
    • Van Bockstaele, E.J., Colago, E.E. &Valentino, R.J. Amygdaloid corticotropin-releasing factor targets locus coeruleus dendrites: substrate for the co-ordination of emotional and cognitive limbs of the stress response. J. Neuroendocrinol. 10, 743-757 (1998)
    • (1998) J. Neuroendocrinol , vol.10 , pp. 743-757
    • Van Bockstaele, E.J.1    Colago, E.E.2    Valentino, R.J.3
  • 49
    • 0028567707 scopus 로고
    • Stress-induced norepinephrine release in the rat prefrontal cortex measured by microdialysis
    • Nakane, H., Shimizu, N. &Hori, T. Stress-induced norepinephrine release in the rat prefrontal cortex measured by microdialysis. Am. J. Physiol. 267, R1559-R1566 (1994)
    • (1994) Am. J. Physiol , vol.267 , pp. R1559-R1566
    • Nakane, H.1    Shimizu, N.2    Hori, T.3
  • 50
    • 84899813827 scopus 로고    scopus 로고
    • Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices
    • Chandler, D.J., Gao, W.J. &Waterhouse, B.D. Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices. Proc. Natl. Acad. Sci. USA 111, 6816-6821 (2014)
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 6816-6821
    • Chandler, D.J.1    Gao, W.J.2    Waterhouse, B.D.3
  • 51
    • 0032150876 scopus 로고    scopus 로고
    • Molecular identification of the cortisone-sensitive extraneuronal catecholamine transporter
    • Gründemann, D., Schechinger, B., Rappold, G.A. &Schomig, E. Molecular identification of the cortisone-sensitive extraneuronal catecholamine transporter. Nat. Neurosci. 1, 349-351 (1998)
    • (1998) Nat. Neurosci , vol.1 , pp. 349-351
    • Gründemann, D.1    Schechinger, B.2    Rappold, G.A.3    Schomig, E.4
  • 52
    • 84864668288 scopus 로고    scopus 로고
    • Sex differences in molecular and cellular substrates of stress
    • Bangasser, D.A. &Valentino, R.J. Sex differences in molecular and cellular substrates of stress. Cell. Mol. Neurobiol. 32, 709-723 (2012)
    • (2012) Cell. Mol. Neurobiol , vol.32 , pp. 709-723
    • Bangasser, D.A.1    Valentino, R.J.2
  • 53
    • 0032565761 scopus 로고    scopus 로고
    • Ovarian hormones influence morphology, distribution and density of tyrosine hydroxylase immunoreactive axons in the dorsolateral prefrontal cortex of adult rhesus monkeys
    • Kritzer, M.F. &Kohama, S.G. Ovarian hormones influence morphology, distribution and density of tyrosine hydroxylase immunoreactive axons in the dorsolateral prefrontal cortex of adult rhesus monkeys. J. Comp. Neurol. 395, 1-17 (1998)
    • (1998) J. Comp. Neurol , vol.395 , pp. 1-17
    • Kritzer, M.F.1    Kohama, S.G.2
  • 54
    • 0033232469 scopus 로고    scopus 로고
    • A role for norepinephrine in stress-induced cognitive deficits and alpha-1-adrenoceptor mediation in prefrontal cortex
    • Birnbaum, S., Gobeske, K.T., Auerbach, J., Taylor, J.R. &Arnsten, A.F.T. A role for norepinephrine in stress-induced cognitive deficits: and alpha;-1-adrenoceptor mediation in prefrontal cortex. Biol. Psychiatry 46, 1266-1274 (1999)
    • (1999) Biol. Psychiatry , vol.46 , pp. 1266-1274
    • Birnbaum, S.1    Gobeske, K.T.2    Auerbach, J.3    Taylor, J.R.4    Arnsten, A.F.T.5
  • 55
    • 0030612013 scopus 로고    scopus 로고
    • Supranormal stimulation of dopamine D1 receptors in the rodent prefrontal cortex impairs spatial working memory performance
    • Zahrt, J., Taylor, J.R., Mathew, R.G. &Arnsten, A.F.T. Supranormal stimulation of dopamine D1 receptors in the rodent prefrontal cortex impairs spatial working memory performance. J. Neurosci. 17, 8528-8535 (1997)
    • (1997) J. Neurosci , vol.17 , pp. 8528-8535
    • Zahrt, J.1    Taylor, J.R.2    Mathew, R.G.3    Arnsten, A.F.T.4
  • 56
    • 0033004430 scopus 로고    scopus 로고
    • Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function
    • Arnsten, A.F.T., Mathew, R., Ubriani, R., Taylor, J.R. &Li, B.-M. Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function. Biol. Psychiatry 45, 26-31 (1999)
    • (1999) Biol. Psychiatry , vol.45 , pp. 26-31
    • Arnsten, A.F.T.1    Mathew, R.2    Ubriani, R.3    Taylor, J.R.4    Li, B.-M.5
  • 57
    • 7444256727 scopus 로고    scopus 로고
    • Protein kinase C overactivity impairs prefrontal cortical regulation of working memory
    • Birnbaum, S.G. et al. Protein kinase C overactivity impairs prefrontal cortical regulation of working memory. Science 306, 882-884 (2004)
    • (2004) Science , vol.306 , pp. 882-884
    • Birnbaum, S.G.1
  • 58
    • 82255195523 scopus 로고    scopus 로고
    • Stress-related noradrenergic activity prompts large-scale neural network reconfiguration
    • Hermans, E.J. et al. Stress-related noradrenergic activity prompts large-scale neural network reconfiguration. Science 334, 1151-1153 (2011)
    • (2011) Science , vol.334 , pp. 1151-1153
    • Hermans, E.J.1
  • 59
    • 84864258460 scopus 로고    scopus 로고
    • Simultaneous glucocorticoid and noradrenergic activity disrupts the neural basis of goal-directed action in the human brain
    • Schwabe, L., Tegenthoff, M., Höffken, O. &Wolf, O.T. Simultaneous glucocorticoid and noradrenergic activity disrupts the neural basis of goal-directed action in the human brain. J. Neurosci. 32, 10146-10155 (2012)
    • (2012) J. Neurosci , vol.32 , pp. 10146-10155
    • Schwabe, L.1    Tegenthoff, M.2    Höffken, O.3    Wolf, O.T.4
  • 60
    • 33847191328 scopus 로고    scopus 로고
    • Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory
    • Vijayraghavan, S. et al. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat. Neurosci. 10, 376-384 (2007)
    • (2007) Nat. Neurosci , vol.10 , pp. 376-384
    • Vijayraghavan, S.1
  • 61
    • 29044438717 scopus 로고    scopus 로고
    • The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys
    • Ramos, B.P. et al. The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys. Biol. Psychiatry 58, 894-900 (2005)
    • (2005) Biol. Psychiatry , vol.58 , pp. 894-900
    • Ramos, B.P.1
  • 62
    • 84942452285 scopus 로고    scopus 로고
    • Stress impairs prefrontal cortical function via D1 dopamine receptor interactions with HCN channels
    • 4 February
    • Gamo, N.J. et al. Stress impairs prefrontal cortical function via D1 dopamine receptor interactions with HCN channels. Biol. Psychiatry doi:10.1016/j.biopsych.2015.01.009 (4 February 2015)
    • (2015) Biol. Psychiatry
    • Gamo, N.J.1
  • 63
    • 0842309863 scopus 로고    scopus 로고
    • Selective D2 receptor actions on the functional circuitry of working memory
    • Wang, M., Vijayraghavan, S. &Goldman-Rakic, P.S. Selective D2 receptor actions on the functional circuitry of working memory. Science 303, 853-856 (2004)
    • (2004) Science , vol.303 , pp. 853-856
    • Wang, M.1    Vijayraghavan, S.2    Goldman-Rakic, P.S.3
  • 64
    • 0033564774 scopus 로고    scopus 로고
    • Basolateral amygdala noradrenergic influences on memory storage are mediated by an interaction between β-and and alpha;1-adrenoceptors
    • Ferry, B., Roozendaal, B. &McGaugh, J.L. Basolateral amygdala noradrenergic influences on memory storage are mediated by an interaction between β-and and alpha;1-adrenoceptors. J. Neurosci. 19, 5119-5123 (1999)
    • (1999) J. Neurosci , vol.19 , pp. 5119-5123
    • Ferry, B.1    Roozendaal, B.2    McGaugh, J.L.3
  • 65
    • 51449122303 scopus 로고    scopus 로고
    • Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
    • Everitt, B.J. et al. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Phil. Trans. R. Soc. Lond. B 363, 3125-3135 (2008)
    • (2008) Phil. Trans. R. Soc. Lond. B , vol.363 , pp. 3125-3135
    • Everitt, B.J.1
  • 66
    • 0018880206 scopus 로고
    • Noradrenergic modulation of somatosensory cortical neuronal responses to iontophoretically applied putative transmitters
    • Waterhouse, B.D., Moises, H.C. &Woodward, D.J. Noradrenergic modulation of somatosensory cortical neuronal responses to iontophoretically applied putative transmitters. Exp. Neurol. 69, 30-49 (1980)
    • (1980) Exp. Neurol , vol.69 , pp. 30-49
    • Waterhouse, B.D.1    Moises, H.C.2    Woodward, D.J.3
  • 67
    • 0025854475 scopus 로고
    • Noradrenergic potentiation of excitatory transmitter action in cerebrocortical slices: Evidence of mediation by an alpha1-receptor-linked second messenger pathway
    • Mouradian, R.D., Seller, F.M. &Waterhouse, B.D. Noradrenergic potentiation of excitatory transmitter action in cerebrocortical slices: evidence of mediation by an alpha1-receptor-linked second messenger pathway. Brain Res. 546, 83-95 (1991)
    • (1991) Brain Res , vol.546 , pp. 83-95
    • Mouradian, R.D.1    Seller, F.M.2    Waterhouse, B.D.3
  • 68
    • 12344303526 scopus 로고    scopus 로고
    • Inhibition of PKC in basolateral amygdala and posterior parietal cortex impairs consolidation of inhibitory avoidance memory
    • Bonini, J.S., Cammarota, M., Kerr, D.S., Bevilaqua, L.R. &Izquierdo, I. Inhibition of PKC in basolateral amygdala and posterior parietal cortex impairs consolidation of inhibitory avoidance memory. Pharmacol. Biochem. Behav. 80, 63-67 (2005)
    • (2005) Pharmacol. Biochem. Behav , vol.80 , pp. 63-67
    • Bonini, J.S.1    Cammarota, M.2    Kerr, D.S.3    Bevilaqua, L.R.4    Izquierdo, I.5
  • 69
    • 78049271284 scopus 로고    scopus 로고
    • Glucocorticoids in the prefrontal cortex enhance memory consolidation and impair working memory by a common neural mechanism
    • Barsegyan, A., Mackenzie, S.M., Kurose, B.D., McGaugh, J.L. &Roozendaal, B. Glucocorticoids in the prefrontal cortex enhance memory consolidation and impair working memory by a common neural mechanism. Proc. Natl. Acad. Sci. USA 107, 16655-16660 (2010)
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 16655-16660
    • Barsegyan, A.1    Mackenzie, S.M.2    Kurose, B.D.3    McGaugh, J.L.4    Roozendaal, B.5
  • 70
    • 0037472343 scopus 로고    scopus 로고
    • Daily injections alter spine density in rat medial prefrontal cortex
    • Seib, L.M. &Wellman, C.L. Daily injections alter spine density in rat medial prefrontal cortex. Neurosci. Lett. 337, 29-32 (2003)
    • (2003) Neurosci. Lett , vol.337 , pp. 29-32
    • Seib, L.M.1    Wellman, C.L.2
  • 71
    • 33747070540 scopus 로고    scopus 로고
    • Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    • Liston, C. et al. Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J. Neurosci. 26, 7870-7874 (2006)
    • (2006) J. Neurosci , vol.26 , pp. 7870-7874
    • Liston, C.1
  • 72
    • 23444432520 scopus 로고    scopus 로고
    • Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    • Radley, J.J. et al. Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp. Neurol. 196, 199-203 (2005)
    • (2005) Exp. Neurol , vol.196 , pp. 199-203
    • Radley, J.J.1
  • 73
    • 66249120082 scopus 로고    scopus 로고
    • Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific
    • Shansky, R.M., Hamo, C., Hof, P.R., McEwen, B.S. &Morrison, J.H. Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific. Cereb. Cortex 19, 2479-2484 (2009)
    • (2009) Cereb. Cortex , vol.19 , pp. 2479-2484
    • Shansky, R.M.1    Hamo, C.2    Hof, P.R.3    McEwen, B.S.4    Morrison, J.H.5
  • 74
    • 84902997661 scopus 로고    scopus 로고
    • REDD1 is essential for stress-induced synaptic loss and depressive behavior
    • Ota, K.T. et al. REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nat. Med. 20, 531-535 (2014)
    • (2014) Nat. Med , vol.20 , pp. 531-535
    • Ota, K.T.1
  • 75
    • 70449584553 scopus 로고    scopus 로고
    • Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress
    • Hains, A.B. et al. Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proc. Natl. Acad. Sci. USA 106, 17957-17962 (2009)
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17957-17962
    • Hains, A.B.1
  • 76
    • 79957651404 scopus 로고    scopus 로고
    • Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex
    • Bloss, E.B. et al. Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex. J. Neurosci. 31, 7831-7839 (2011)
    • (2011) J. Neurosci , vol.31 , pp. 7831-7839
    • Bloss, E.B.1
  • 77
    • 0036703905 scopus 로고    scopus 로고
    • Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons
    • Vyas, A., Mitra, R., Shankaranarayana Rao, B.S. &Chattarji, S. Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J. Neurosci. 22, 6810-6818 (2002)
    • (2002) J. Neurosci , vol.22 , pp. 6810-6818
    • Vyas, A.1    Mitra, R.2    Shankaranarayana, R.B.S.3    Chattarji, S.4
  • 78
  • 79
    • 84861999740 scopus 로고    scopus 로고
    • Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions
    • Ansell, E.B., Rando, K., Tuit, K., Guarnaccia, J. &Sinha, R. Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions. Biol. Psychiatry 72, 57-64 (2012)
    • (2012) Biol. Psychiatry , vol.72 , pp. 57-64
    • Ansell, E.B.1    Rando, K.2    Tuit, K.3    Guarnaccia, J.4    Sinha, R.5
  • 80
    • 58849162391 scopus 로고    scopus 로고
    • Psychosocial stress reversibly disrupts prefrontal processing and attentional control
    • Liston, C., McEwen, B.S. &Casey, B.J. Psychosocial stress reversibly disrupts prefrontal processing and attentional control. Proc. Natl. Acad. Sci. USA 106, 912-917 (2009)
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 912-917
    • Liston, C.1    McEwen, B.S.2    Casey, B.J.3
  • 81
    • 84887430648 scopus 로고    scopus 로고
    • Effects of childhood poverty and chronic stress on emotion regulatory brain function in adulthood
    • Kim, P. et al. Effects of childhood poverty and chronic stress on emotion regulatory brain function in adulthood. Proc. Natl. Acad. Sci. USA 110, 18442-18447 (2013)
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 18442-18447
    • Kim, P.1
  • 82
    • 84863738913 scopus 로고    scopus 로고
    • Stress-induced changes in human decision-making are reversible
    • Soares, J.M. et al. Stress-induced changes in human decision-making are reversible. Transl. Psychiatry 2, e131 (2012)
    • (2012) Transl. Psychiatry , vol.2 , pp. e131
    • Soares, J.M.1
  • 83
    • 0026598924 scopus 로고
    • Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: Effects of chronic stress and drug treatments
    • Melia, K.R. et al. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: effects of chronic stress and drug treatments. J. Neurochem. 58, 494-502 (1992)
    • (1992) J. Neurochem , vol.58 , pp. 494-502
    • Melia, K.R.1
  • 84
    • 32544452050 scopus 로고    scopus 로고
    • Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex
    • Miner, L.H. et al. Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex. J. Neurosci. 26, 1571-1578 (2006)
    • (2006) J. Neurosci , vol.26 , pp. 1571-1578
    • Miner, L.H.1
  • 85
    • 84876423156 scopus 로고    scopus 로고
    • Effects of chronic social defeat on expression of dopamine β-hydroxylase in rat brains
    • Fan, Y., Chen, P., Li, Y. &Zhu, M.Y. Effects of chronic social defeat on expression of dopamine β-hydroxylase in rat brains. Synapse 67, 300-312 (2013)
    • (2013) Synapse , vol.67 , pp. 300-312
    • Fan, Y.1    Chen, P.2    Li, Y.3    Zhu, M.Y.4
  • 86
    • 84868468411 scopus 로고    scopus 로고
    • Function and innervation of the locus ceruleus in a macaque model of functional hypothalamic amenorrhea
    • Bethea, C.L., Kim, A. &Cameron, J.L. Function and innervation of the locus ceruleus in a macaque model of functional hypothalamic amenorrhea. Neurobiol. Dis. 50, 96-106 (2013)
    • (2013) Neurobiol. Dis , vol.50 , pp. 96-106
    • Bethea, C.L.1    Kim, A.2    Cameron, J.L.3
  • 87
    • 0033232479 scopus 로고    scopus 로고
    • Molecular control of locus coeruleus neurotransmission
    • Nestler, E.J., Alreja, M. &Aghajanian, G.K. Molecular control of locus coeruleus neurotransmission. Biol. Psychiatry 46, 1131-1139 (1999)
    • (1999) Biol. Psychiatry , vol.46 , pp. 1131-1139
    • Nestler, E.J.1    Alreja, M.2    Aghajanian, G.K.3
  • 88
    • 0042423405 scopus 로고    scopus 로고
    • Elevated concentrations of CRF in the locus coeruleus of depressed subjects
    • Bissette, G., Klimek, V., Pan, J., Stockmeier, C. &Ordway, G. Elevated concentrations of CRF in the locus coeruleus of depressed subjects. Neuropsychopharmacology 28, 1328-1335 (2003)
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1328-1335
    • Bissette, G.1    Klimek, V.2    Pan, J.3    Stockmeier, C.4    Ordway, G.5
  • 89
    • 84908179208 scopus 로고    scopus 로고
    • Galanin mediates features of neural and behavioral stress resilience afforded by exercise
    • Sciolino, N.R. et al. Galanin mediates features of neural and behavioral stress resilience afforded by exercise. Neuropharmacology 89, 255-264 (2015)
    • (2015) Neuropharmacology , vol.89 , pp. 255-264
    • Sciolino, N.R.1
  • 90
    • 0034652088 scopus 로고    scopus 로고
    • Chronic stress induces impairment of spatial working memory due to prefrontal dopaminergic dysfunction
    • Mizoguchi, K. et al. Chronic stress induces impairment of spatial working memory due to prefrontal dopaminergic dysfunction. J. Neurosci. 20, 1568-1574 (2000)
    • (2000) J. Neurosci , vol.20 , pp. 1568-1574
    • Mizoguchi, K.1
  • 91
    • 84906086338 scopus 로고    scopus 로고
    • Neurochemical and behavioral effects of chronic unpredictable stress
    • Matuszewich, L., McFadden, L.M., Friedman, R.D. &Frye, C.A. Neurochemical and behavioral effects of chronic unpredictable stress. Behav. Pharmacol. 25, 557-566 (2014)
    • (2014) Behav. Pharmacol , vol.25 , pp. 557-566
    • Matuszewich, L.1    McFadden, L.M.2    Friedman, R.D.3    Frye, C.A.4
  • 92
    • 84920626140 scopus 로고    scopus 로고
    • D1 receptors regulate dendritic morphology in normal and stressed prelimbic cortex
    • Lin, G.L., Borders, C.B., Lundewall, L.J. &Wellman, C.L. D1 receptors regulate dendritic morphology in normal and stressed prelimbic cortex. Psychoneuroendocrinology 51, 101-111 (2015)
    • (2015) Psychoneuroendocrinology , vol.51 , pp. 101-111
    • Lin, G.L.1    Borders, C.B.2    Lundewall, L.J.3    Wellman, C.L.4
  • 93
    • 0028114577 scopus 로고
    • Synaptic development of the cerebral cortex: Implications for learning, memory, and mental illness
    • Rakic, P., Bourgeois, J.P. &Goldman-Rakic, P.S. Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness. Prog. Brain Res. 102, 227-243 (1994)
    • (1994) Prog. Brain Res , vol.102 , pp. 227-243
    • Rakic, P.1    Bourgeois, J.P.2    Goldman-Rakic, P.S.3
  • 94
    • 77953189368 scopus 로고    scopus 로고
    • Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment
    • Dumitriu, D. et al. Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment. J. Neurosci. 30, 7507-7515 (2010)
    • (2010) J. Neurosci , vol.30 , pp. 7507-7515
    • Dumitriu, D.1
  • 95
    • 84890547494 scopus 로고    scopus 로고
    • Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
    • Chung, W.S. et al. Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways. Nature 504, 394-400 (2013)
    • (2013) Nature , vol.504 , pp. 394-400
    • Chung, W.S.1
  • 96
    • 25644436461 scopus 로고    scopus 로고
    • Essential role for the PKC target MARCKS in maintaining dendritic spine morphology
    • Calabrese, B. &Halpain, S. Essential role for the PKC target MARCKS in maintaining dendritic spine morphology. Neuron 48, 77-90 (2005)
    • (2005) Neuron , vol.48 , pp. 77-90
    • Calabrese, B.1    Halpain, S.2
  • 97
    • 84925633561 scopus 로고    scopus 로고
    • Chronic stimulation of alpha-2A-adrenoceptors with guanfacine protects rodent prefrontal cortex dendritic spines and cognition from the effects of chronic stress
    • Hains, A.B., Yabe, Y. &Arnsten, A.F.T. Chronic stimulation of alpha-2A-adrenoceptors with guanfacine protects rodent prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Neurobiol. Stress 2, 1-9 (2015)
    • (2015) Neurobiol. Stress , vol.2 , pp. 1-9
    • Hains, A.B.1    Yabe, Y.2    Arnsten, A.F.T.3
  • 98
    • 34147105096 scopus 로고    scopus 로고
    • 2A-adrenoceptor stimulation strengthens working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex
    • Wang, M. et al. 2A-adrenoceptor stimulation strengthens working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129, 397-410 (2007)
    • (2007) Cell , vol.129 , pp. 397-410
    • Wang, M.1
  • 99
    • 0037691848 scopus 로고    scopus 로고
    • 2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: Involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD
    • DeBock, F. et al. 2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD. Eur. J. Neurosci. 17, 1411-1424 (2003)
    • (2003) Eur. J. Neurosci , vol.17 , pp. 1411-1424
    • DeBock, F.1
  • 100
    • 5644286647 scopus 로고    scopus 로고
    • Noradrenergic and alpha;-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry
    • Morrow, B.A., George, T.P. &Roth, R.H. Noradrenergic and alpha;-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry. Brain Res. 1027, 173-178 (2004)
    • (2004) Brain Res , vol.1027 , pp. 173-178
    • Morrow, B.A.1    George, T.P.2    Roth, R.H.3
  • 101
    • 0025896714 scopus 로고
    • Effects of alpha 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats
    • Engberg, G. &Eriksson, E. Effects of alpha 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats. Naunyn Schmiedebergs Arch. Pharmacol. 343, 472-477 (1991)
    • (1991) Naunyn Schmiedebergs Arch. Pharmacol , vol.343 , pp. 472-477
    • Engberg, G.1    Eriksson, E.2
  • 102
    • 84878255569 scopus 로고    scopus 로고
    • Norepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors
    • Gyoneva, S. &Traynelis, S.F. Norepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors. J. Biol. Chem. 288, 15291-15302 (2013)
    • (2013) J. Biol. Chem , vol.288 , pp. 15291-15302
    • Gyoneva, S.1    Traynelis, S.F.2
  • 103
    • 84856748892 scopus 로고    scopus 로고
    • Pharmacotherapy of attention-deficit hyperactivity disorder in adolescents
    • Childress, A.C. &Berry, S.A. Pharmacotherapy of attention-deficit hyperactivity disorder in adolescents. Drugs 72, 309-325 (2012)
    • (2012) Drugs , vol.72 , pp. 309-325
    • Childress, A.C.1    Berry, S.A.2
  • 104
    • 84891898331 scopus 로고    scopus 로고
    • Rapid induction of REDD1 gene expression in macrophages in response to stress-related catecholamines
    • Yanagawa, Y., Hiraide, S., Matsumoto, M. &Togashi, H. Rapid induction of REDD1 gene expression in macrophages in response to stress-related catecholamines. Immunol. Lett. 158, 109-115 (2014)
    • (2014) Immunol Lett , vol.158 , pp. 109-115
    • Yanagawa, Y.1    Hiraide, S.2    Matsumoto, M.3    Togashi, H.4
  • 105
    • 68249104457 scopus 로고    scopus 로고
    • REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase
    • Katiyar, S. et al. REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase. EMBO Rep. 10, 866-872 (2009)
    • (2009) EMBO Rep , vol.10 , pp. 866-872
    • Katiyar, S.1
  • 106
    • 84885392284 scopus 로고    scopus 로고
    • Guanfacine is an effective countermeasure for hypobaric hypoxia-induced cognitive decline
    • Kauser, H., Sahu, S., Kumar, S. &Panjwani, U. Guanfacine is an effective countermeasure for hypobaric hypoxia-induced cognitive decline. Neuroscience 254, 110-119 (2013)
    • (2013) Neuroscience , vol.254 , pp. 110-119
    • Kauser, H.1    Sahu, S.2    Kumar, S.3    Panjwani, U.4
  • 107
    • 33746696008 scopus 로고    scopus 로고
    • Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: Implications for prefrontal dysfunction
    • Kobori, N., Clifton, G.L. &Dash, P.K. Enhanced catecholamine synthesis in the prefrontal cortex after traumatic brain injury: implications for prefrontal dysfunction. J. Neurotrauma 23, 1094-1102 (2006)
    • (2006) J. Neurotrauma , vol.23 , pp. 1094-1102
    • Kobori, N.1    Clifton, G.L.2    Dash, P.K.3
  • 108
    • 78650723389 scopus 로고    scopus 로고
    • Altered adrenergic receptor signaling following traumatic brain injury contributes to working memory dysfunction
    • Kobori, N., Hu, B. &Dash, P.K. Altered adrenergic receptor signaling following traumatic brain injury contributes to working memory dysfunction. Neuroscience 172, 293-302 (2011)
    • (2011) Neuroscience , vol.172 , pp. 293-302
    • Kobori, N.1    Hu, B.2    Dash, P.K.3
  • 109
    • 82255162372 scopus 로고    scopus 로고
    • Post-traumatic stress disorder vs traumatic brain injury
    • Bryant, R. Post-traumatic stress disorder vs traumatic brain injury. Dialogues Clin. Neurosci. 13, 251-262 (2011)
    • (2011) Dialogues Clin. Neurosci , vol.13 , pp. 251-262
    • Bryant, R.1
  • 110
    • 84858742061 scopus 로고    scopus 로고
    • Traumatic brain injury: A risk factor for Alzheimer's disease
    • Sivanandam, T.M. &Thakur, M.K. Traumatic brain injury: a risk factor for Alzheimer's disease. Neurosci. Biobehav. Rev. 36, 1376-1381 (2012)
    • (2012) Neurosci. Biobehav. Rev , vol.36 , pp. 1376-1381
    • Sivanandam, T.M.1    Thakur, M.K.2
  • 111
    • 84921928728 scopus 로고    scopus 로고
    • The effects of stress exposure on prefrontal cortex: Translating basic research into successful treatments for post-traumatic stress disorder
    • This paper reviews how studies of stress effects in animals have led to successful treatments for PTSD in humans
    • Arnsten, A.F.T., Raskind, M., Taylor, F.B. &Connor, D.F. The effects of stress exposure on prefrontal cortex: translating basic research into successful treatments for post-traumatic stress disorder. Neurobiol. Stress 1, 89-99 (2015). This paper reviews how studies of stress effects in animals have led to successful treatments for PTSD in humans
    • (2015) Neurobiol. Stress , vol.1 , pp. 89-99
    • Arnsten, A.F.T.1    Raskind, M.2    Taylor, F.B.3    Connor, D.F.4
  • 112
    • 84924664636 scopus 로고    scopus 로고
    • A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation
    • McKee, S. et al. A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation. J. Psychopharmacol. 29, 300-311 (2015)
    • (2015) J. Psychopharmacol , vol.29 , pp. 300-311
    • McKee, S.1
  • 113
    • 84924696573 scopus 로고    scopus 로고
    • Guanfacine enhances inhibitory control and attentional shifting in early abstinent cocaine-dependent individuals
    • 7 January
    • Fox, H., Sofuoglu, M. &Sinha, R. Guanfacine enhances inhibitory control and attentional shifting in early abstinent cocaine-dependent individuals. J. Psychopharmacol. 29, 312-323 (7 January 2015)
    • (2015) J. Psychopharmacol , vol.29 , pp. 312-323
    • Fox, H.1    Sofuoglu, M.2    Sinha, R.3
  • 114
    • 84878025227 scopus 로고    scopus 로고
    • An open-label study of guanfacine extended release for traumatic stress related symptoms in children and adolescents
    • Connor, D.F., Grasso, D.J., Slivinsky, M.D., Pearson, G.S. &Banga, A. An open-label study of guanfacine extended release for traumatic stress related symptoms in children and adolescents. J. Child Adolesc. Psychopharmacol. 23, 244-251 (2013)
    • (2013) J. Child Adolesc. Psychopharmacol , vol.23 , pp. 244-251
    • Connor, D.F.1    Grasso, D.J.2    Slivinsky, M.D.3    Pearson, G.S.4    Banga, A.5
  • 115
    • 84884285513 scopus 로고    scopus 로고
    • Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression
    • Licznerski, P. &Duman, R.S. Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression. Neuroscience 251, 33-50 (2013)
    • (2013) Neuroscience , vol.251 , pp. 33-50
    • Licznerski, P.1    Duman, R.S.2
  • 116
    • 84896029352 scopus 로고    scopus 로고
    • Neuropathological and neuromorphometric abnormalities in bipolar disorder: View from the medial prefrontal cortical network
    • Savitz, J.B., Price, J.L. &Drevets, W.C. Neuropathological and neuromorphometric abnormalities in bipolar disorder: view from the medial prefrontal cortical network. Neurosci. Biobehav. Rev. 42, 132-147 (2014)
    • (2014) Neurosci. Biobehav. Rev , vol.42 , pp. 132-147
    • Savitz, J.B.1    Price, J.L.2    Drevets, W.C.3
  • 117
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz, L.A. &Lewis, D.A. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch. Gen. Psychiatry 57, 65-73 (2000)
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 118
    • 1842428190 scopus 로고    scopus 로고
    • Pathology of layer v pyramidal neurons in the prefrontal cortex of patients with schizophrenia
    • Black, J.E. et al. Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia. Am. J. Psychiatry 161, 742-744 (2004)
    • (2004) Am. J. Psychiatry , vol.161 , pp. 742-744
    • Black, J.E.1
  • 119
    • 84946494256 scopus 로고    scopus 로고
    • Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
    • 6 January
    • Arion, D. et al. Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder. Mol. Psychiatry doi:10.1038/mp.2014.171 (6 January 2015)
    • (2015) Mol. Psychiatry
    • Arion, D.1
  • 121
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • Millar, J.K. et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310, 1187-1191 (2005)
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1
  • 122
    • 27744554247 scopus 로고    scopus 로고
    • Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short-and long-term memory
    • Cannon, T.D. et al. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short-and long-term memory. Arch. Gen. Psychiatry 62, 1205-1213 (2005)
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1
  • 123
    • 47949105098 scopus 로고    scopus 로고
    • DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia
    • Szeszko, P.R. et al. DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biol. Psychol. 79, 103-110 (2008)
    • (2008) Biol. Psychol , vol.79 , pp. 103-110
    • Szeszko, P.R.1
  • 124
    • 33845748185 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 interactome: Evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
    • Camargo, L.M. et al. Disrupted in Schizophrenia 1 interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Mol. Psychiatry 12, 74-86 (2007)
    • (2007) Mol. Psychiatry , vol.12 , pp. 74-86
    • Camargo, L.M.1
  • 125
    • 79954527672 scopus 로고    scopus 로고
    • Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation
    • MacKenzie, K.F. et al. Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation. Biochem. J. 435, 755-769 (2011)
    • (2011) Biochem. J , vol.435 , pp. 755-769
    • MacKenzie, K.F.1
  • 126
    • 33744985583 scopus 로고    scopus 로고
    • DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
    • Kirkpatrick, B. et al. DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J. Comp. Neurol. 497, 436-450 (2006)
    • (2006) J. Comp. Neurol , vol.497 , pp. 436-450
    • Kirkpatrick, B.1
  • 127
    • 84878888401 scopus 로고    scopus 로고
    • Constellation of HCN channels and cAMP regulating proteins in dendritic spines of the primate prefrontal cortex-potential substrate for working memory deficits in schizophrenia
    • Paspalas, C.D., Min Wang, M. &Arnsten, A.F.T. Constellation of HCN channels and cAMP regulating proteins in dendritic spines of the primate prefrontal cortex-potential substrate for working memory deficits in schizophrenia. Cereb. Cortex 23, 1643-1654 (2013)
    • (2013) Cereb. Cortex , vol.23 , pp. 1643-1654
    • Paspalas, C.D.1    Min Wang, M.2    Arnsten, A.F.T.3
  • 128
    • 80052491357 scopus 로고    scopus 로고
    • Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia
    • Deng, X. et al. Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 156, 850-858 (2011)
    • (2011) Am. J. Med. Genet. B. Neuropsychiatr. Genet , vol.156 , pp. 850-858
    • Deng, X.1
  • 129
    • 84907598135 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels
    • El-Hassar, L. et al. Disrupted in Schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels. Biol. Psychiatry 76, 476-485 (2014)
    • (2014) Biol. Psychiatry , vol.76 , pp. 476-485
    • El-Hassar, L.1
  • 130
    • 84890213480 scopus 로고    scopus 로고
    • Role of Disrupted in Schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction
    • Gamo, N.J. et al. Role of Disrupted in Schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction. Transl. Psychiatry 3, e328 (2013)
    • (2013) Transl. Psychiatry , vol.3 , pp. e328
    • Gamo, N.J.1
  • 131
    • 77649192502 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
    • Hayashi-Takagi, A. et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat. Neurosci. 13, 327-332 (2010)
    • (2010) Nat. Neurosci , vol.13 , pp. 327-332
    • Hayashi-Takagi, A.1
  • 132
    • 84899630780 scopus 로고    scopus 로고
    • PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence
    • Hayashi-Takagi, A. et al. PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence. Proc. Natl. Acad. Sci. USA 111, 6461-6466 (2014)
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 6461-6466
    • Hayashi-Takagi, A.1
  • 133
    • 84899450687 scopus 로고    scopus 로고
    • Interplay of pka and rac: Fine-tuning of rac localization and signaling
    • Bachmann, V.A., Bister, K. &Stefan, E. Interplay of PKA and Rac: fine-tuning of Rac localization and signaling. Small GTPases 4, 247-251 (2013)
    • (2013) Small GTPases , vol.4 , pp. 247-251
    • Bachmann, V.A.1    Bister, K.2    Stefan, E.3
  • 134
    • 33745698814 scopus 로고    scopus 로고
    • Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia
    • Hill, J.J., Hashimoto, T. &Lewis, D.A. Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol. Psychiatry 11, 557-566 (2006)
    • (2006) Mol. Psychiatry , vol.11 , pp. 557-566
    • Hill, J.J.1    Hashimoto, T.2    Lewis, D.A.3
  • 135
    • 77953615507 scopus 로고    scopus 로고
    • Altered cortical CDC42 signaling pathways in schizophrenia: Implications for dendritic spine deficits
    • Ide, M. &Lewis, D.A. Altered cortical CDC42 signaling pathways in schizophrenia: implications for dendritic spine deficits. Biol. Psychiatry 68, 25-32 (2010)
    • (2010) Biol. Psychiatry , vol.68 , pp. 25-32
    • Ide, M.1    Lewis, D.A.2
  • 136
    • 0037847431 scopus 로고    scopus 로고
    • IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton
    • Briggs, M.W. &Sacks, D.B. IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton. FEBS Lett. 542, 7-11 (2003)
    • (2003) FEBS Lett , vol.542 , pp. 7-11
    • Briggs, M.W.1    Sacks, D.B.2
  • 137
    • 0038708285 scopus 로고    scopus 로고
    • Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
    • Giannakopoulos, P. et al. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology 60, 1495-1500 (2003)
    • (2003) Neurology , vol.60 , pp. 1495-1500
    • Giannakopoulos, P.1
  • 138
    • 0345512210 scopus 로고
    • Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease
    • Pearson, R.C.A., Esiri, M.M., Hiorns, R.W., Wilcock, G.K. &Powell, T.P.S. Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proc. Natl. Acad. Sci. USA 82, 4531-4534 (1985)
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4531-4534
    • Pearson, R.C.A.1    Esiri, M.M.2    Hiorns, R.W.3    Wilcock, G.K.4    Powell, T.P.S.5
  • 139
    • 0023222380 scopus 로고
    • Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices
    • Lewis, D.A., Campbell, M.J., Terry, R.D. &Morrison, J.H. Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices. J. Neurosci. 7, 1799-1808 (1987)
    • (1987) J. Neurosci , vol.7 , pp. 1799-1808
    • Lewis, D.A.1    Campbell, M.J.2    Terry, R.D.3    Morrison, J.H.4
  • 140
    • 0034724427 scopus 로고    scopus 로고
    • Head injury and the risk of AD in the MIRAGE study
    • Guo, Z. et al. Head injury and the risk of AD in the MIRAGE study. Neurology 54, 1316-1323 (2000)
    • (2000) Neurology , vol.54 , pp. 1316-1323
    • Guo, Z.1
  • 141
    • 84899917388 scopus 로고    scopus 로고
    • Sex modifies the APOE-related risk of developing Alzheimer disease
    • Alzheimer's Disease Neuroimaging Initiative Investigators
    • Altmann, A., Tian, L., Henderson, V.W., Greicius, M.D. &Alzheimer's Disease Neuroimaging Initiative Investigators. Sex modifies the APOE-related risk of developing Alzheimer disease. Ann. Neurol. 75, 563-573 (2014)
    • (2014) Ann. Neurol , vol.75 , pp. 563-573
    • Altmann, A.1    Tian, L.2    Henderson, V.W.3    Greicius, M.D.4
  • 142
    • 0037472631 scopus 로고    scopus 로고
    • Stress-induced hyperphosphorylation of tau in the mouse brain
    • Okawa, Y., Ishiguro, K. &Fujita, S.C. Stress-induced hyperphosphorylation of tau in the mouse brain. FEBS Lett. 535, 183-189 (2003)
    • (2003) FEBS Lett , vol.535 , pp. 183-189
    • Okawa, Y.1    Ishiguro, K.2    Fujita, S.C.3
  • 143
    • 84861230374 scopus 로고    scopus 로고
    • The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport
    • Bhalla, A. et al. The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. Neurobiol. Dis. 47, 126-134 (2012)
    • (2012) Neurobiol. Dis , vol.47 , pp. 126-134
    • Bhalla, A.1
  • 144
    • 34248202513 scopus 로고    scopus 로고
    • Modulation of β-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family
    • Cam, J.A. &Bu, G. Modulation of β-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family. Mol. Neurodegener. 1, 8 (2006)
    • (2006) Mol. Neurodegener , vol.1 , pp. 8
    • Cam, J.A.1    Bu, G.2
  • 145
    • 84919627574 scopus 로고    scopus 로고
    • ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA
    • Yajima, R. et al. ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA. Biochem. Biophys. Res. Commun. 456, 482-488 (2015)
    • (2015) Biochem. Biophys. Res. Commun , vol.456 , pp. 482-488
    • Yajima, R.1
  • 146
    • 77953658771 scopus 로고    scopus 로고
    • Deleterious effects of amyloid β oligomers acting as an extracellular scaffold for mGluR5
    • Renner, M. et al. Deleterious effects of amyloid β oligomers acting as an extracellular scaffold for mGluR5. Neuron 66, 739-754 (2010)
    • (2010) Neuron , vol.66 , pp. 739-754
    • Renner, M.1
  • 147
    • 84884200967 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein
    • Um, J.W. et al. Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. Neuron 79, 887-902 (2013)
    • (2013) Neuron , vol.79 , pp. 887-902
    • Um, J.W.1
  • 148
    • 84897935089 scopus 로고    scopus 로고
    • Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis
    • Doens, D. &Fernández, P.L. Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis. J. Neuroinflammation 11, 48 (2014)
    • (2014) J. Neuroinflammation , vol.11 , pp. 48
    • Doens, D.1    Fernández, P.L.2
  • 149
    • 79958034385 scopus 로고    scopus 로고
    • Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: Coupled mechanisms of energy metabolism regulation
    • Acin-Perez, R., Gatti, D.L., Bai, Y. &Manfredi, G. Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: coupled mechanisms of energy metabolism regulation. Cell Metab. 13, 712-719 (2011)
    • (2011) Cell Metab , vol.13 , pp. 712-719
    • Acin-Perez, R.1    Gatti, D.L.2    Bai, Y.3    Manfredi, G.4
  • 150
    • 38849150935 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress causes hyperphosphorylation of tau
    • Melov, S. et al. Mitochondrial oxidative stress causes hyperphosphorylation of tau. PLoS ONE 2, e536 (2007)
    • (2007) PLoS ONE , vol.2 , pp. e536
    • Melov, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.