Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 3, 1996, Pages 1325-1329

  Murphy, B L ^a   Arnsten, A F T ^a   Goldman Rakic, P S ^a   Roth, R H ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

clozapine; FG7142; haloperidol; RO15 1788; SCH23390

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; BETA CARBOLINE DERIVATIVE; CLOZAPINE; DOPAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; FLUMAZENIL; HALOPERIDOL; N METHYL BETA CARBOLINE 3 CARBOXAMIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN FUNCTION; COGNITIVE DEFECT; CONTROLLED STUDY; DOPAMINE METABOLISM; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MONKEY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; STRESS; TASK PERFORMANCE;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANALYSIS OF VARIANCE; ANIMALS; CARBOLINES; CLOZAPINE; DOPAMINE; DOPAMINE ANTAGONISTS; FEMALE; FLUMAZENIL; GABA MODULATORS; HALOPERIDOL; MACACA MULATTA; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SPACE PERCEPTION; STRESS, PSYCHOLOGICAL;

ANIMALIA;

EID: 0030033256     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.3.1325     Document Type: Article

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