Altered Cortical CDC42 Signaling Pathways in Schizophrenia: Implications for Dendritic Spine Deficits

Biological Psychiatry

Volumn 68, Issue 1, 2010, Pages 25-32

  Ide, Masayuki ^a   Lewis, David A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

CDC42; dendritic spine; mRNA; prefrontal cortex; schizophrenia; septin

Indexed keywords

ACTIN; BIOLOGICAL MARKER; CELL DIVISION CYCLE 42 EFFECTOR PROTEIN 3; CELL DIVISION CYCLE 42 EFFECTOR PROTEIN 4; CELL DIVISION CYCLE 42 PROTEIN; HALOPERIDOL; MESSENGER RNA; OLANZAPINE; POSTSYNAPTIC DENSITY PROTEIN 95; REGULATOR PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SEPTIN; SEPTIN 11; SEPTIN 2; SEPTIN 3; SEPTIN 5; SEPTIN 6; SEPTIN 7; SEPTIN 8; SPINOPHILIN; SYNAPTOPODIN; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; ANILLIN; CDC42EP3 PROTEIN, HUMAN; CONTRACTILE PROTEIN; CYTOSKELETON PROTEIN; DLG4 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; NEURABIN; NEUROLEPTIC AGENT; PROTEIN CDC42; SIGNAL PEPTIDE; SYNAPTOPHYSIN; SYNPR PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DENDRITIC SPINE; DRUG BLOOD LEVEL; HUMAN; HUMAN TISSUE; MACACA; MALE; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; ADULT; ANALYSIS OF VARIANCE; ANIMAL; CASE CONTROL STUDY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MACACA FASCICULARIS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY;

ADULT; ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; CASE-CONTROL STUDIES; CDC42 GTP-BINDING PROTEIN; CONTRACTILE PROTEINS; CYTOSKELETAL PROTEINS; DENDRITIC SPINES; FEMALE; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN REGULATORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACACA FASCICULARIS; MALE; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; PREFRONTAL CORTEX; PYRAMIDAL CELLS; RNA, MESSENGER; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SYNAPTOPHYSIN;

EID: 77953615507     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.02.016     Document Type: Article

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