Chronic stimulation of alpha-2A-adrenoceptors with guanfacine protects rodent prefrontal cortex dendritic spines and cognition from the effects of chronic stress

Neurobiology of Stress

Volumn 2, Issue , 2015, Pages 1-9

  Hains, Avis Brennan ^a,b   Yabe, Yoko ^a,c   Arnsten, Amy F T ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b 713 Bayview Way ^*  (United States)

^c Columbia University College of Physicians and Surgeons Office ^*  (United States)

Author keywords

Attention deficit hyperactivity disorder; Norepinephrine; Post traumatic stress disorder; Working memory

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CYCLIC AMP; GUANFACINE; POTASSIUM CHANNEL;

ACUTE STRESS; ACUTE STRESS DISORDER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BODY WEIGHT; BRAIN CORTEX ATROPHY; CALCIUM SIGNALING; CELL DENSITY; CHRONIC STRESS; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; EXPERIMENTAL REWARD ADDICTION TEST; GRAY MATTER; MALE; MEMORY DISORDER; MENTAL DISEASE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; REVIEW; SPATIAL MEMORY; SPATIAL MEMORY TEST; STIMULATION; T-MAZE TEST; WORKING MEMORY;

EID: 84925633561     PISSN: None     EISSN: 23522895     Source Type: Journal    
DOI: 10.1016/j.ynstr.2015.01.001     Document Type: Article

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