Supranormal stimulation of D1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance

Journal of Neuroscience

Volumn 17, Issue 21, 1997, Pages 8528-8535

  Zahrt, Justin ^a   Taylor, Jane R ^a   Mathew, Rex G ^a   Arnsten, Amy F T ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

D1 receptor; Dopamine; Prefrontal cortex; Schizophrenia; Stress; Working memory

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE; DOPAMINE 1 RECEPTOR; BENZAZEPINE DERIVATIVE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SK&F 81297;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MALE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; REGULATORY MECHANISM; SCHIZOPHRENIA; STRESS; WORKING MEMORY; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; INFUSION; MAZE TEST; MEMORY; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL MODEL; PSYCHOMOTOR PERFORMANCE; SPRAGUE DAWLEY RAT;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; BENZAZEPINES; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; INFUSIONS, PARENTERAL; MALE; MAZE LEARNING; MEMORY; MODELS, NEUROLOGICAL; MODELS, PSYCHOLOGICAL; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, N-METHYL-D-ASPARTATE; SPATIAL BEHAVIOR; STRESS, PSYCHOLOGICAL;

EID: 0030612013     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-21-08528.1997     Document Type: Article

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