Interleukin-1α deficiency attenuates endoplasmic reticulum stress-induced liver damage and CHOP expression in mice

Journal of Hepatology

Volumn 63, Issue 4, 2015, Pages 926-933

  Kandel Kfir, Michal ^a   Almog, Tal ^a   Shaish, Aviv ^a   Shlomai, Gadi ^a   Anafi, Liat ^a   Avivi, Camila ^a   Barshack, Iris ^a,b   Grosskopf, Itamar ^a   Harats, Dror ^a,b   Kamari, Yehuda ^a,b  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Apoptosis; CHOP; ER stress; IL 1 ; Necrosis; Steatohepatitis

Indexed keywords

CASPASE 3; CHOLESTEROL; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; DDIT3 PROTEIN, MOUSE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROGENIC DIET; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; INFLAMMATION; INTERLEUKIN 1ALPHA DEFICIENCY; LIVER CELL; LIVER INJURY; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DEFICIENCY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LIVER DISEASE; MALE; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; INTERLEUKIN-1ALPHA; LIVER DISEASES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTOR CHOP;

EID: 84941935794     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.05.012     Document Type: Article

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