Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice

Atherosclerosis

Volumn 222, Issue 2, 2012, Pages 329-336

  Shemesh, Shay ^a,b   Kamari, Yehuda ^a,c   Shaish, Aviv ^a   Olteanu, Sarita ^a,c   Kandel Kfir, Michal ^a   Almog, Tal ^a   Grosskopf, Itamar ^a   Apte, Ron N ^d   Harats, Dror ^a,c  

^a SHEBA MEDICAL CENTER   (Israel)

^b BAR ILAN UNIVERSITY   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Apolipoprotein E; Atherosclerosis; IL 1 receptor; Inflammation; Mice

Indexed keywords

APOLIPOPROTEIN E; CD68 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPID; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; AORTA SINUS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD VESSEL WALL; BONE MARROW; CONTROLLED STUDY; CYTOKINE PRODUCTION; KNOCKOUT MOUSE; LIPID BLOOD LEVEL; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN TARGETING;

ANIMALS; AORTA; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BODY WEIGHT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1; LIPIDS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RADIATION CHIMERA; RECEPTORS, INTERLEUKIN-1 TYPE I; RNA, MESSENGER; TIME FACTORS;

EID: 84858701880     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.12.010     Document Type: Article

References (30)

1. Kleemann R., Zadelaar S., Kooistra T. Cytokines and atherosclerosis: a comprehensive review of studies in mice. Cardiovasc Res 2008, 79:360-376.
2. Bernhagen J., Krohn R., Lue H., et al. MIF is a non-cognate ligand of cxc chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med 2007, 13:587-596.
3. Bevilacqua M.P., Pober J.S., Majeau G.R., Cotran R.S., Gimbrone M.A. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J Exp Med 1984, 160:618-623.
4. Libby P., Ordovas J.M., Birinyi L.K., Auger K.R., Dinarello C.A. Inducible interleukin-1 gene expression in human vascular smooth muscle cells. J Clin Invest 1986, 78:1432-1438.
5. Fantuzzi G., Zheng H., Faggioni R., et al. Effect of endotoxin in IL-1beta-deficient mice. J Immunol 1996, 157:291-296.
6. Dinarello C.A. Historical insights into cytokines. Eur J Immunol 2007, 37(Suppl. 1):S34-S45.
7. Dinarello C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009, 27:519-550.
8. Colotta F., Re F., Muzio M., et al. Interleukin-1 type 2 receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993, 261:472-475.
9. Moyer C.F., Sajuthi D., Tulli H., Williams J.K. Synthesis of IL-1alpha and IL-1beta by arterial cells in atherosclerosis. Am J Pathol 1991, 138:951-960.
10. Tipping P.G., Hancock W.W. Production of tumor necrosis factor and interleukin-1 by macrophages from human atheromatous plaques. Am J Pathol 1993, 142:1721-1728.
11. Galea J., Armstrong J., Gadsdon P., et al. Interleukin-1beta in coronary arteries of patients with ischemic heart disease. Arterioscler Thromb Vasc Biol 1996, 16:1000-1006.
12. Kirii H., Niwa T., Yamada Y., et al. Lack of interleukin-1beta decreases the severity of atherosclerosis in apoe-deficient mice. Arterioscler Thromb Vasc Biol 2003, 23:656-660.
13. Isoda K., Sawada S., Ishigami N., et al. Lack of interleukin-1 receptor antagonist modulates plaque composition in apolipoprotein e-deficient mice. Arterioscler Thromb Vasc Biol 2004, 24:1068-1073.
14. Chamberlain J., Francis S., Brookes Z., et al. Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PloS One 2009, 4:e5073.
15. Chi H., Messas E., Levine R.A., Graves D.T., Amar S. Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein e heterozygote model: pharmacotherapeutic implications. Circulation 2004, 110:1678-1685.
16. Elhage R., Maret A., Pieraggi M.T., et al. Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein e-deficient mice. Circulation 1998, 97:242-244.
17. Devlin C.M., Kuriakose G., Hirsch E., Tabas I. Genetic alterations of IL-1 receptor antagonist in mice affect plasma cholesterol level and foam cell lesion size. Proc Natl Acad Sci U S A 2002, 99:6280-6285.
18. Duewell P., Kono H., Rayner K.J., et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010, 464:1357-1361.
19. Kamari Y., Shaish A., Shemesh S., et al. Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-e-deficient mice lacking bone marrow-derived interleukin-1alpha. Biochem Biophys Res Commun 2011, 405:197-203.
20. Kamari Y., Werman-Venkert R., Shaish A., et al. Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis 2007, 195:31-38.
21. Garcia M.C., Wernstedt I., Berndtsson A., et al. Mature-onset obesity in interleukin-1 receptor I knockout mice. Diabetes 2006, 55:1205-1213.
22. Getz G.S., Reardon C.A. Diet and murine atherosclerosis. Arterioscler Thromb Vasc Biol 2006, 26:242-249.
23. Fettelschoss A., Kistowska M., Leibundgut-Landmann S., et al. Inflammasome activation and IL-1beta target IL-1alpha for secretion as opposed to surface expression. Proc Natl Acad Sci U S A 2011, 108:18055-18060.
24. Isoda K., Shiigai M., Ishigami N., et al. Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury. Circulation 2003, 108:516-518.
25. Kamari Y., Shaish A., Vax E., et al. Lack of interleukin-1alpha or interleukin-1beta inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J Hepatol 2011, 55:1086-1094.
26. Cybulsky M.I., Gimbrone M.A. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 1991, 251:788-791.
27. Gu L., Okada Y., Clinton S.K., et al. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 1998, 2:275-281.
28. Collins R.G., Velji R., Guevara N.V., et al. P-selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein e-deficient mice. J Exp Med 2000, 191:189-194.
29. Cha J.K., Jeong M.H., Bae H.R., et al. Activated platelets induce secretion of interleukin-1beta, monocyte chemotactic protein-1, and macrophage inflammatory protein-1alpha and surface expression of intercellular adhesion molecule-1 on cultured endothelial cells. J Korean Med Sci 2000, 15:273-278.
30. Thornton P., McColl B.W., Greenhalgh A., et al. Platelet interleukin-1alpha drives cerebrovascular inflammation. Blood 2010, 115:3632-3639.