TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice

Journal of Clinical Investigation

Volumn 114, Issue 11, 2004, Pages 1603-1611

  Horai, Reiko ^a,b   Nakajima, Akiko ^a   Habiro, Katsuyoshi ^c   Kotani, Motoko ^c   Nakae, Susumu ^a,f   Matsuki, Taizo ^a,g   Nambu, Aya ^a   Saijo, Shinobu ^a   Kotaki, Hayato ^a   Sudo, Katsuko ^a,h   Okahara, Akihiko ^d   Tanioka, Hidetoshi ^d   Ikuse, Toshimi ^d   Ishii, Naoto ^e   Schwartzberg, Pamela L ^b   Abe, Ryo ^c   Iwakura, Yoichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d SANTEN PHARMACEUTICAL CO LTD   (Japan)

^e TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^h TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD134 ANTIGEN; CD40 LIGAND; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; ANTIRHEUMATIC AGENT; CD40 ANTIGEN; CYTOKINE; IL1RN PROTEIN, MOUSE; SIALOGLYCOPROTEIN; TNFRSF4 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE EXPRESSION; GENE INDUCTION; HOMEOSTASIS; IMMUNE SYSTEM; MOUSE STRAIN; NONHUMAN; OX40 GENE; PRIORITY JOURNAL; PROTEIN INTERACTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL TRANSPLANTATION; CYTOLOGY; DRUG ANTAGONISM; GENETICS; IMMUNOLOGY; JOINT; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; MOUSE MUTANT; NUDE MOUSE; PATHOLOGY; RHEUMATOID ARTHRITIS;

ANIMALS; ANTIGENS, CD40; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL TRANSPLANTATION; CYTOKINES; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; JOINTS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NUDE; MICE, SCID; RECEPTORS, INTERLEUKIN-1; RECEPTORS, OX40; RECEPTORS, TUMOR NECROSIS FACTOR; SIALOGLYCOPROTEINS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85047693264     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI20742     Document Type: Article

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