메뉴 건너뛰기




Volumn 12, Issue 9, 2015, Pages 3105-3118

Taming Cell Penetrating Peptides: Never Too Old to Teach Old Dogs New Tricks

Author keywords

cell penetrating peptides (CPPs); drug delivery systems; improved efficiency; responsive; selectivity

Indexed keywords

ANION; CELL PENETRATING PEPTIDE; GALA PEPTIDE; HISTIDINE; LIPOSOME; PEPTIDE NUCLEIC ACID; PH LOW INSERTION PEPTIDE; UNCLASSIFIED DRUG; NANOPARTICLE;

EID: 84941102169     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00428     Document Type: Article
Times cited : (35)

References (154)
  • 1
    • 0024262589 scopus 로고
    • Cellular uptake of the tat protein from human immunodeficiency virus
    • Frankel, A. D.; Pabo, C. O. Cellular uptake of the tat protein from human immunodeficiency virus Cell 1988, 55, 1189-1193 10.1016/0092-8674(88)90263-2
    • (1988) Cell , vol.55 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 3
    • 0042232110 scopus 로고    scopus 로고
    • Studies on the internalization mechanism of cationic cell-penetrating peptides
    • Drin, G.; Cottin, S.; Blanc, E.; Rees, A. R.; Temsamani, J. Studies on the internalization mechanism of cationic cell-penetrating peptides J. Biol. Chem. 2003, 278 (33) 31192-31201 10.1074/jbc.M303938200
    • (2003) J. Biol. Chem. , vol.278 , Issue.33 , pp. 31192-31201
    • Drin, G.1    Cottin, S.2    Blanc, E.3    Rees, A.R.4    Temsamani, J.5
  • 4
    • 0345275894 scopus 로고    scopus 로고
    • Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential
    • Terrone, D.; Sang, S. L.; Roudaia, L.; Silvius, J. R. Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential Biochemistry 2003, 42 (47) 13787-13799 10.1021/bi035293y
    • (2003) Biochemistry , vol.42 , Issue.47 , pp. 13787-13799
    • Terrone, D.1    Sang, S.L.2    Roudaia, L.3    Silvius, J.R.4
  • 5
    • 34848892144 scopus 로고    scopus 로고
    • Cell penetrating peptides: Intracellular pathways and pharmaceutical perspectives
    • Patel, L. N.; Zaro, J. L.; Shen, W. C. Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives Pharm. Res. 2007, 24 (11) 1977-1992 10.1007/s11095-007-9303-7
    • (2007) Pharm. Res. , vol.24 , Issue.11 , pp. 1977-1992
    • Patel, L.N.1    Zaro, J.L.2    Shen, W.C.3
  • 6
    • 0035204427 scopus 로고    scopus 로고
    • A peptide carrier for the delivery of biologically active proteins into mammalian cells
    • Morris, M. C.; Depollier, J.; Mery, J.; Heitz, F.; Divita, G. A peptide carrier for the delivery of biologically active proteins into mammalian cells Nat. Biotechnol. 2001, 19, 1173-1176 10.1038/nbt1201-1173
    • (2001) Nat. Biotechnol. , vol.19 , pp. 1173-1176
    • Morris, M.C.1    Depollier, J.2    Mery, J.3    Heitz, F.4    Divita, G.5
  • 8
    • 23944483437 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
    • Deshayes, S.; Morris, M. C.; Divita, G.; Heitz, F. Cell-penetrating peptides: tools for intracellular delivery of therapeutics Cell. Mol. Life Sci. 2005, 62 (16) 1839-1849 10.1007/s00018-005-5109-0
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.16 , pp. 1839-1849
    • Deshayes, S.1    Morris, M.C.2    Divita, G.3    Heitz, F.4
  • 9
    • 70449698651 scopus 로고    scopus 로고
    • Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD
    • Watkins, C. L.; Brennan, P.; Fegan, C.; Takayama, K.; Nakase, I.; Futaki, S.; Jones, A. T. Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD J. Controlled Release 2009, 140 (3) 237-244 10.1016/j.jconrel.2009.04.028
    • (2009) J. Controlled Release , vol.140 , Issue.3 , pp. 237-244
    • Watkins, C.L.1    Brennan, P.2    Fegan, C.3    Takayama, K.4    Nakase, I.5    Futaki, S.6    Jones, A.T.7
  • 10
    • 84864631153 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Classes, origin, and current landscape
    • Milletti, F. Cell-penetrating peptides: classes, origin, and current landscape Drug Discovery Today 2012, 17 (15-16) 850-860 10.1016/j.drudis.2012.03.002
    • (2012) Drug Discovery Today , vol.17 , Issue.1516 , pp. 850-860
    • Milletti, F.1
  • 11
    • 13844298046 scopus 로고    scopus 로고
    • Intracellular delivery of large molecules and small particles by cell-penetrating proteins andpeptides
    • Gupta, B.; Levchenko, T. S.; Torchilin, V. P. Intracellular delivery of large molecules and small particles by cell-penetrating proteins andpeptides Adv. Drug Delivery Rev. 2005, 57 (4) 637-651 10.1016/j.addr.2004.10.007
    • (2005) Adv. Drug Delivery Rev. , vol.57 , Issue.4 , pp. 637-651
    • Gupta, B.1    Levchenko, T.S.2    Torchilin, V.P.3
  • 12
    • 45749120326 scopus 로고    scopus 로고
    • Cell-penetrating peptides as delivery vehicles for biology and medicine
    • Stewart, K. M.; Horton, K. L.; Kelley, S. O. Cell-penetrating peptides as delivery vehicles for biology and medicine Org. Biomol. Chem. 2008, 6 (13) 2242-2255 10.1039/b719950c
    • (2008) Org. Biomol. Chem. , vol.6 , Issue.13 , pp. 2242-2255
    • Stewart, K.M.1    Horton, K.L.2    Kelley, S.O.3
  • 13
    • 9644289511 scopus 로고    scopus 로고
    • The use of cell-penetrating peptides for drug delivery
    • Temsamani, J.; Vidal, P. The use of cell-penetrating peptides for drug delivery Drug Discovery Today 2004, 9 (23) 1012-1019 10.1016/S1359-6446(04)03279-9
    • (2004) Drug Discovery Today , vol.9 , Issue.23 , pp. 1012-1019
    • Temsamani, J.1    Vidal, P.2
  • 14
    • 77949890248 scopus 로고    scopus 로고
    • Cell penetrating peptides: Overview and applications to the delivery of oligonucleotides
    • Said Hassane, F.; Saleh, A. F.; Abes, R.; Gait, M. J.; Lebleu, B. Cell penetrating peptides: overview and applications to the delivery of oligonucleotides Cell. Mol. Life Sci. 2010, 67 (5) 715-26 10.1007/s00018-009-0186-0
    • (2010) Cell. Mol. Life Sci. , vol.67 , Issue.5 , pp. 715-726
    • Said Hassane, F.1    Saleh, A.F.2    Abes, R.3    Gait, M.J.4    Lebleu, B.5
  • 15
    • 28444461040 scopus 로고    scopus 로고
    • Present and future of cell-penetrating peptide mediated delivery systems: Is the Trojan horse too wild to go only to Troy?
    • Vives, E. Present and future of cell-penetrating peptide mediated delivery systems: Is the Trojan horse too wild to go only to Troy? J. Controlled Release 2005, 109 (1-3) 77-85 10.1016/j.jconrel.2005.09.032
    • (2005) J. Controlled Release , vol.109 , Issue.13 , pp. 77-85
    • Vives, E.1
  • 16
    • 84885382019 scopus 로고    scopus 로고
    • Curb challenges of the "rojan Horse" approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery
    • Huang, Y.; Jiang, Y.; Wang, H.; Wang, J.; Shin, M. C.; Byun, Y.; He, H.; Liang, Y.; Yang, V. C. Curb challenges of the "rojan Horse" approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery Adv. Drug Delivery Rev. 2013, 65 (10) 1299-1315 10.1016/j.addr.2012.11.007
    • (2013) Adv. Drug Delivery Rev. , vol.65 , Issue.10 , pp. 1299-1315
    • Huang, Y.1    Jiang, Y.2    Wang, H.3    Wang, J.4    Shin, M.C.5    Byun, Y.6    He, H.7    Liang, Y.8    Yang, V.C.9
  • 17
    • 84907207085 scopus 로고    scopus 로고
    • A survey on "rojan Horse" peptides: Opportunities, issues and controlled entry to "roy
    • Shi, N. Q.; Qi, X. R.; Xiang, B.; Zhang, Y. A survey on "rojan Horse" peptides: Opportunities, issues and controlled entry to "roy J. Controlled Release 2014, 194, 53-70 10.1016/j.jconrel.2014.08.014
    • (2014) J. Controlled Release , vol.194 , pp. 53-70
    • Shi, N.Q.1    Qi, X.R.2    Xiang, B.3    Zhang, Y.4
  • 18
    • 84863099046 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Breaking through to the other side
    • Koren, E.; Torchilin, V. P. Cell-penetrating peptides: breaking through to the other side Trends Mol. Med. 2012, 18 (7) 385-393 10.1016/j.molmed.2012.04.012
    • (2012) Trends Mol. Med. , vol.18 , Issue.7 , pp. 385-393
    • Koren, E.1    Torchilin, V.P.2
  • 20
    • 84901343834 scopus 로고    scopus 로고
    • Cell penetrating peptides: Efficient vectors for delivery of nanoparticles, nanocarriers therapeutic and diagnostic molecules
    • Farkhani, S. M.; Valizadeh, A.; Karami, H.; Mohammadi, S.; Sohrabi, N.; Badrzadeh, F. Cell penetrating peptides: Efficient vectors for delivery of nanoparticles, nanocarriers therapeutic and diagnostic molecules Peptides 2014, 57, 78-94 10.1016/j.peptides.2014.04.015
    • (2014) Peptides , vol.57 , pp. 78-94
    • Farkhani, S.M.1    Valizadeh, A.2    Karami, H.3    Mohammadi, S.4    Sohrabi, N.5    Badrzadeh, F.6
  • 21
    • 38949188925 scopus 로고    scopus 로고
    • Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides
    • Nakase, I.; Takeuchi, T.; Tanaka, G.; Futaki, S. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides Adv. Drug Delivery Rev. 2008, 60 (4-5) 598-607 10.1016/j.addr.2007.10.006
    • (2008) Adv. Drug Delivery Rev. , vol.60 , Issue.45 , pp. 598-607
    • Nakase, I.1    Takeuchi, T.2    Tanaka, G.3    Futaki, S.4
  • 22
    • 84873428784 scopus 로고    scopus 로고
    • Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis
    • Bechara, C.; Pallerla, M.; Zaltsman, Y.; Burlina, F.; Alves, I. D.; Lequin, O.; Sagan, S. Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis FASEB J. 2013, 27 (2) 738-749 10.1096/fj.12-216176
    • (2013) FASEB J. , vol.27 , Issue.2 , pp. 738-749
    • Bechara, C.1    Pallerla, M.2    Zaltsman, Y.3    Burlina, F.4    Alves, I.D.5    Lequin, O.6    Sagan, S.7
  • 23
    • 27544478703 scopus 로고    scopus 로고
    • The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine
    • Schröder-Borm, H.; Bakalova, R.; Andrä, J. The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine FEBS Lett. 2005, 579 (27) 6128-6134 10.1016/j.febslet.2005.09.084
    • (2005) FEBS Lett. , vol.579 , Issue.27 , pp. 6128-6134
    • Schröder-Borm, H.1    Bakalova, R.2    Andrä, J.3
  • 24
    • 33744916273 scopus 로고    scopus 로고
    • Inhibition of Tumor Growth and Elimination of Multiple Metastasesi n Human Prostate and Breast Xenografts by Systemic Inoculation of a Host Defense-Like Lytic Peptide
    • Papo, N.; Seger, D.; Makovitzki, A.; Kalchenko, V.; Eshhar, Z.; Degani, H.; Shai, Y. Inhibition of Tumor Growth and Elimination of Multiple Metastasesi n Human Prostate and Breast Xenografts by Systemic Inoculation of a Host Defense-Like Lytic Peptide Cancer Res. 2006, 66 (10) 5371-5378 10.1158/0008-5472.CAN-05-4569
    • (2006) Cancer Res. , vol.66 , Issue.10 , pp. 5371-5378
    • Papo, N.1    Seger, D.2    Makovitzki, A.3    Kalchenko, V.4    Eshhar, Z.5    Degani, H.6    Shai, Y.7
  • 25
    • 84915817769 scopus 로고    scopus 로고
    • On the importance of electrostatic interactions between cell penetrating peptides and membranes: A pathway toward tumor cell selectivity?
    • Jobin, M. L.; Alves, I. D. On the importance of electrostatic interactions between cell penetrating peptides and membranes: A pathway toward tumor cell selectivity? Biochimie 2014, 107, 154-159 10.1016/j.biochi.2014.07.022
    • (2014) Biochimie , vol.107 , pp. 154-159
    • Jobin, M.L.1    Alves, I.D.2
  • 26
    • 84864062843 scopus 로고    scopus 로고
    • Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans
    • Amand, H. L.; Rydberg, H. A.; Fornander, L. H.; Lincoln, P.; Nordén, B.; Esbjörner, E. K. Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans Biochim. Biophys. Acta, Biomembr. 2012, 1818 (11) 2669-2678 10.1016/j.bbamem.2012.06.006
    • (2012) Biochim. Biophys. Acta, Biomembr. , vol.1818 , Issue.11 , pp. 2669-2678
    • Amand, H.L.1    Rydberg, H.A.2    Fornander, L.H.3    Lincoln, P.4    Nordén, B.5    Esbjörner, E.K.6
  • 27
    • 79958093000 scopus 로고    scopus 로고
    • Contributions of glycosaminoglycan binding and clustering to the biological uptake of the nonamphipathic cell-penetrating peptide WR9
    • Ziegler, A.; Seelig, J. Contributions of glycosaminoglycan binding and clustering to the biological uptake of the nonamphipathic cell-penetrating peptide WR9 Biochemistry 2011, 50 (21) 4650-4664 10.1021/bi1019429
    • (2011) Biochemistry , vol.50 , Issue.21 , pp. 4650-4664
    • Ziegler, A.1    Seelig, J.2
  • 28
    • 84874933223 scopus 로고    scopus 로고
    • The enhanced membrane interaction and perturbation of a cell penetrating peptide in the presence of anionic lipids: Toward an understanding of its selectivity for cancer cells
    • Jobin, M. L.; Bonnafous, P.; Temsamani, H.; Dole, F.; Grélard, A.; Dufourc, E. J.; Alves, I. D. The enhanced membrane interaction and perturbation of a cell penetrating peptide in the presence of anionic lipids: Toward an understanding of its selectivity for cancer cells Biochim. Biophys. Acta, Biomembr. 2013, 1828 (6) 1457-1470 10.1016/j.bbamem.2013.02.008
    • (2013) Biochim. Biophys. Acta, Biomembr. , vol.1828 , Issue.6 , pp. 1457-1470
    • Jobin, M.L.1    Bonnafous, P.2    Temsamani, H.3    Dole, F.4    Grélard, A.5    Dufourc, E.J.6    Alves, I.D.7
  • 29
    • 80053440806 scopus 로고    scopus 로고
    • Membrane-active host defense peptides - Challenges and perspectives for the development of novel anticancer drugs
    • Riedl, S.; Zweytick, D.; Lohner, K. Membrane-active host defense peptides-Challenges and perspectives for the development of novel anticancer drugs Chem. Phys. Lipids 2011, 164 (8) 766-781 10.1016/j.chemphyslip.2011.09.004
    • (2011) Chem. Phys. Lipids , vol.164 , Issue.8 , pp. 766-781
    • Riedl, S.1    Zweytick, D.2    Lohner, K.3
  • 30
    • 52949148197 scopus 로고    scopus 로고
    • Cell penetrating peptides for in vivo molecular imaging applications
    • Kersemans, V.; Kersemans, K.; Cornelissen, B. Cell penetrating peptides for in vivo molecular imaging applications Curr. Pharm. Des. 2008, 14 (24) 2415-2447 10.2174/138161208785777432
    • (2008) Curr. Pharm. Des. , vol.14 , Issue.24 , pp. 2415-2447
    • Kersemans, V.1    Kersemans, K.2    Cornelissen, B.3
  • 31
    • 84919341605 scopus 로고    scopus 로고
    • Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules
    • Herce, H. D.; Garcia, A. E.; Cardoso, M. C. Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules J. Am. Chem. Soc. 2014, 136 (50) 17459-17467 10.1021/ja507790z
    • (2014) J. Am. Chem. Soc. , vol.136 , Issue.50 , pp. 17459-17467
    • Herce, H.D.1    Garcia, A.E.2    Cardoso, M.C.3
  • 32
    • 77955051682 scopus 로고    scopus 로고
    • Design of a dual-ligand system using a specific ligand and cell penetrating peptide, resulting in a synergistic effect on selectivity and cellular uptake
    • Takara, K.; Hatakeyama, H.; Ohga, N.; Hida, K.; Harashima, H. Design of a dual-ligand system using a specific ligand and cell penetrating peptide, resulting in a synergistic effect on selectivity and cellular uptake Int. J. Pharm. 2010, 396 (1-2) 143-148 10.1016/j.ijpharm.2010.05.002
    • (2010) Int. J. Pharm. , vol.396 , Issue.12 , pp. 143-148
    • Takara, K.1    Hatakeyama, H.2    Ohga, N.3    Hida, K.4    Harashima, H.5
  • 33
    • 79960100272 scopus 로고    scopus 로고
    • Dual-ligand modification of PEGylated liposomes shows better cell selectivity and efficient gene delivery
    • Kibria, G.; Hatakeyama, H.; Ohga, N.; Hida, K.; Harashima, H. Dual-ligand modification of PEGylated liposomes shows better cell selectivity and efficient gene delivery J. Controlled Release 2011, 153 (2) 141-148 10.1016/j.jconrel.2011.03.012
    • (2011) J. Controlled Release , vol.153 , Issue.2 , pp. 141-148
    • Kibria, G.1    Hatakeyama, H.2    Ohga, N.3    Hida, K.4    Harashima, H.5
  • 34
    • 84884136525 scopus 로고    scopus 로고
    • Synergistic targeted delivery of payload into tumor cells by dual-ligand liposomes co-modified with cholesterol anchored transferrin and TAT
    • Tang, J.; Zhang, L.; Liu, Y.; Zhang, Q.; Qin, Y.; Yin, Y.; Yuan, W.; Yang, Y.; Xie, Y.; Zhang, Z.; He, Q. Synergistic targeted delivery of payload into tumor cells by dual-ligand liposomes co-modified with cholesterol anchored transferrin and TAT Int. J. Pharm. 2013, 454 (1) 31-40 10.1016/j.ijpharm.2013.06.048
    • (2013) Int. J. Pharm. , vol.454 , Issue.1 , pp. 31-40
    • Tang, J.1    Zhang, L.2    Liu, Y.3    Zhang, Q.4    Qin, Y.5    Yin, Y.6    Yuan, W.7    Yang, Y.8    Xie, Y.9    Zhang, Z.10    He, Q.11
  • 35
    • 84903984711 scopus 로고    scopus 로고
    • Synergistic dual-ligand doxorubicin liposomes improve targeting and therapeutic efficacy of brain glioma in animals
    • Zong, T.; Mei, L.; Gao, H.; Cai, W.; Zhu, P.; Shi, K.; Chen, J.; Wang, Y.; Gao, F.; He, Q. Synergistic dual-ligand doxorubicin liposomes improve targeting and therapeutic efficacy of brain glioma in animals Mol. Pharmaceutics 2014, 11 (7) 2346-2357 10.1021/mp500057n
    • (2014) Mol. Pharmaceutics , vol.11 , Issue.7 , pp. 2346-2357
    • Zong, T.1    Mei, L.2    Gao, H.3    Cai, W.4    Zhu, P.5    Shi, K.6    Chen, J.7    Wang, Y.8    Gao, F.9    He, Q.10
  • 36
    • 84924964682 scopus 로고    scopus 로고
    • Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery
    • Yang, Y.; Yang, Y.; Xie, X.; Wang, Z.; Gong, W.; Zhang, H.; Li, Y.; Yu, F.; Li, Z.; Mei, X. Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery Biomaterials 2015, 48, 84-96 10.1016/j.biomaterials.2015.01.030
    • (2015) Biomaterials , vol.48 , pp. 84-96
    • Yang, Y.1    Yang, Y.2    Xie, X.3    Wang, Z.4    Gong, W.5    Zhang, H.6    Li, Y.7    Yu, F.8    Li, Z.9    Mei, X.10
  • 37
    • 78649315943 scopus 로고    scopus 로고
    • To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
    • Danhier, F.; Feron, O.; Préat, V. To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery J. Controlled Release 2010, 148 (2) 135-146 10.1016/j.jconrel.2010.08.027
    • (2010) J. Controlled Release , vol.148 , Issue.2 , pp. 135-146
    • Danhier, F.1    Feron, O.2    Préat, V.3
  • 38
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail, D. F.; Joyce, J. A. Microenvironmental regulation of tumor progression and metastasis Nat. Med. 2013, 19 (11) 1423-1437 10.1038/nm.3394
    • (2013) Nat. Med. , vol.19 , Issue.11 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 39
    • 77955915567 scopus 로고    scopus 로고
    • Liposomes as "smart"pharmaceutical nanocarriers
    • Sawant, R. R.; Torchilin, V. P. Liposomes as "smart"pharmaceutical nanocarriers Soft Matter 2010, 6, 4026-4044 10.1039/b923535n
    • (2010) Soft Matter , vol.6 , pp. 4026-4044
    • Sawant, R.R.1    Torchilin, V.P.2
  • 40
    • 84861670821 scopus 로고    scopus 로고
    • Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity
    • Koren, E.; Apte, A.; Jani, A.; Torchilin, V. P. Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity J. Controlled Release 2012, 160 (2) 264-273 10.1016/j.jconrel.2011.12.002
    • (2012) J. Controlled Release , vol.160 , Issue.2 , pp. 264-273
    • Koren, E.1    Apte, A.2    Jani, A.3    Torchilin, V.P.4
  • 41
    • 82955240708 scopus 로고    scopus 로고
    • Targeted Delivery of Cargoes into a Murine Solid Tumor by a Cell-Penetrating Peptide and Cleavable Poly(ethylene glycol) Comodified Liposomal Delivery System via Systemic Administration
    • Kuai, R.; Yuan, W.; Li, W.; Qin, Y.; Tang, J.; Yuan, M.; Fu, L.; Ran, R.; Zhang, Z.; He, Q. Targeted Delivery of Cargoes into a Murine Solid Tumor by a Cell-Penetrating Peptide and Cleavable Poly(ethylene glycol) Comodified Liposomal Delivery System via Systemic Administration Mol. Pharmaceutics 2011, 8 (6) 2151-2161 10.1021/mp200100f
    • (2011) Mol. Pharmaceutics , vol.8 , Issue.6 , pp. 2151-2161
    • Kuai, R.1    Yuan, W.2    Li, W.3    Qin, Y.4    Tang, J.5    Yuan, M.6    Fu, L.7    Ran, R.8    Zhang, Z.9    He, Q.10
  • 42
    • 79953066932 scopus 로고    scopus 로고
    • A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
    • Hatakeyama, H.; Akita, H.; Harashima, H. A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma Adv. Drug Delivery Rev. 2011, 63 (3) 152-160 10.1016/j.addr.2010.09.001
    • (2011) Adv. Drug Delivery Rev. , vol.63 , Issue.3 , pp. 152-160
    • Hatakeyama, H.1    Akita, H.2    Harashima, H.3
  • 43
    • 84860365171 scopus 로고    scopus 로고
    • Matrix metalloprotease 2-responsive multifunctional liposomal nanocarrier for enhanced tumor targeting
    • Zhu, L.; Kate, P.; Torchilin, V. P. Matrix metalloprotease 2-responsive multifunctional liposomal nanocarrier for enhanced tumor targeting ACS Nano 2012, 6 (4) 3491-3498 10.1021/nn300524f
    • (2012) ACS Nano , vol.6 , Issue.4 , pp. 3491-3498
    • Zhu, L.1    Kate, P.2    Torchilin, V.P.3
  • 44
    • 84924911894 scopus 로고    scopus 로고
    • Efficient delivery of payload into tumor cells in a controlled manner by TAT and thiolytic cleavable PEG co-modified liposomes
    • He, L.; Lai, H.; Chen, T. Efficient delivery of payload into tumor cells in a controlled manner by TAT and thiolytic cleavable PEG co-modified liposomes Biomaterials 2015, 51, 30-42 10.1016/j.biomaterials.2015.01.063
    • (2015) Biomaterials , vol.51 , pp. 30-42
    • He, L.1    Lai, H.2    Chen, T.3
  • 45
    • 14644433029 scopus 로고    scopus 로고
    • Super pH-Sensitive Multifunctional Polymeric Micelle
    • Lee, E. S.; Na, K.; Bae, Y. H. Super pH-Sensitive Multifunctional Polymeric Micelle Nano Lett. 2005, 5 (2) 325-329 10.1021/nl0479987
    • (2005) Nano Lett. , vol.5 , Issue.2 , pp. 325-329
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 46
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle for tumor pHespecific TAT exposure and multidrug resistance
    • Lee, E. S.; Gao, Z.; Kim, D.; Park, K.; Kwon, I. C.; Bae, Y. H. Super pH-sensitive multifunctional polymeric micelle for tumor pHespecific TAT exposure and multidrug resistance J. Controlled Release 2008, 129 (3) 228-326 10.1016/j.jconrel.2008.04.024
    • (2008) J. Controlled Release , vol.129 , Issue.3 , pp. 228-326
    • Lee, E.S.1    Gao, Z.2    Kim, D.3    Park, K.4    Kwon, I.C.5    Bae, Y.H.6
  • 47
    • 79958164983 scopus 로고    scopus 로고
    • Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles
    • Gao, Z. G.; Tian, L.; Hu, J.; Park, I. S.; Bae, Y. H. Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles J. Controlled Release 2011, 152 (1) 84-89 10.1016/j.jconrel.2011.01.021
    • (2011) J. Controlled Release , vol.152 , Issue.1 , pp. 84-89
    • Gao, Z.G.1    Tian, L.2    Hu, J.3    Park, I.S.4    Bae, Y.H.5
  • 48
    • 84868546970 scopus 로고    scopus 로고
    • Constrained and UV-activatable cell-penetrating peptides for intracellular delivery of liposomes
    • Hansen, M. B.; van Gaal, E.; Minten, I.; Storm, G.; van Hest, J. C.; Löwik, D. W. Constrained and UV-activatable cell-penetrating peptides for intracellular delivery of liposomes J. Controlled Release 2012, 164 (1) 87-94 10.1016/j.jconrel.2012.10.008
    • (2012) J. Controlled Release , vol.164 , Issue.1 , pp. 87-94
    • Hansen, M.B.1    Van Gaal, E.2    Minten, I.3    Storm, G.4    Van Hest, J.C.5    Löwik, D.W.6
  • 49
    • 30344451098 scopus 로고    scopus 로고
    • Two-dimensional separation of peptides using RP-RP-HPLC system with different pH in first and second separation dimensions
    • Gilar, M.; Olivova, P.; Daly, A. E.; Gebler, J. C. Two-dimensional separation of peptides using RP-RP-HPLC system with different pH in first and second separation dimensions J. Sep. Sci. 2005, 28 (14) 1694-1703 10.1002/jssc.200500116
    • (2005) J. Sep. Sci. , vol.28 , Issue.14 , pp. 1694-1703
    • Gilar, M.1    Olivova, P.2    Daly, A.E.3    Gebler, J.C.4
  • 51
    • 84906809118 scopus 로고    scopus 로고
    • Stepwise-Acid-Active Multifunctional Mesoporous Silica Nanoparticles for Tumor-Specific Nucleus-Targeted Drug Delivery
    • Li, Z. Y.; Liu, Y.; Hu, J. J.; Xu, Q.; Liu, L. H.; Jia, H. Z.; Chen, W. H.; Lei, Q.; Rong, L.; Zhang, X. Z. Stepwise-Acid-Active Multifunctional Mesoporous Silica Nanoparticles for Tumor-Specific Nucleus-Targeted Drug Delivery ACS Appl. Mater. Interfaces 2014, 6 (16) 14568-14575 10.1021/am503846p
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , Issue.16 , pp. 14568-14575
    • Li, Z.Y.1    Liu, Y.2    Hu, J.J.3    Xu, Q.4    Liu, L.H.5    Jia, H.Z.6    Chen, W.H.7    Lei, Q.8    Rong, L.9    Zhang, X.Z.10
  • 52
    • 84903625230 scopus 로고    scopus 로고
    • Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment
    • Liu, Z.; Xiong, M.; Gong, J.; Zhang, Y.; Bai, N.; Luo, Y.; Li, L.; Wei, Y.; Liu, Y.; Tan, X.; Xiang, R. Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment Nat. Commun. 2014, 5, 4280 10.1038/ncomms5280
    • (2014) Nat. Commun. , vol.5 , pp. 4280
    • Liu, Z.1    Xiong, M.2    Gong, J.3    Zhang, Y.4    Bai, N.5    Luo, Y.6    Li, L.7    Wei, Y.8    Liu, Y.9    Tan, X.10    Xiang, R.11
  • 53
    • 84921466125 scopus 로고    scopus 로고
    • Activatable Cell Penetrating Peptide-Peptide Nucleic Acid Conjugate via Reduction of Azobenzene PEG Chains
    • Lee, S. H.; Moroz, E.; Castagner, B.; Leroux, J. C. Activatable Cell Penetrating Peptide-Peptide Nucleic Acid Conjugate via Reduction of Azobenzene PEG Chains J. Am. Chem. Soc. 2014, 136 (37) 12868-12871 10.1021/ja507547w
    • (2014) J. Am. Chem. Soc. , vol.136 , Issue.37 , pp. 12868-12871
    • Lee, S.H.1    Moroz, E.2    Castagner, B.3    Leroux, J.C.4
  • 54
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • Wender, P. A.; Mitchell, D. J.; Pattabiraman, K.; Pelkey, E. T.; Steinman, L.; Rothbard, J. B. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters Proc. Natl. Acad. Sci. U. S. A. 2000, 97 (24) 13003-13008 10.1073/pnas.97.24.13003
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.24 , pp. 13003-13008
    • Wender, P.A.1    Mitchell, D.J.2    Pattabiraman, K.3    Pelkey, E.T.4    Steinman, L.5    Rothbard, J.B.6
  • 56
    • 44149128392 scopus 로고    scopus 로고
    • Stimulated endocytosis in penetratin uptake: Effect of arginine and lysine
    • Amand, H. L.; Fant, K.; Nordén, B.; Esbjörner, E. K. Stimulated endocytosis in penetratin uptake: effect of arginine and lysine Biochem. Biophys. Res. Commun. 2008, 371 (4) 621-625 10.1016/j.bbrc.2008.04.039
    • (2008) Biochem. Biophys. Res. Commun. , vol.371 , Issue.4 , pp. 621-625
    • Amand, H.L.1    Fant, K.2    Nordén, B.3    Esbjörner, E.K.4
  • 57
    • 70549109798 scopus 로고    scopus 로고
    • Isolation of novel cell-penetrating peptides from a random peptide library using in vitro virus and their modifications
    • Kamide, K.; Nakakubo, H.; Uno, S.; Fukamizu, A. Isolation of novel cell-penetrating peptides from a random peptide library using in vitro virus and their modifications Int. J. Mol. Med. 2010, 25 (1) 41-51 10.3892/ijmm-00000311
    • (2010) Int. J. Mol. Med. , vol.25 , Issue.1 , pp. 41-51
    • Kamide, K.1    Nakakubo, H.2    Uno, S.3    Fukamizu, A.4
  • 58
    • 80052748271 scopus 로고    scopus 로고
    • Cellular uptake of transportan 10 and its analogs in live cells: Selectivity and structure-activity relationship studies
    • Song, J.; Kai, M.; Zhang, W.; Zhang, J.; Liu, L.; Zhang, B.; Liu, X.; Wang, R. Cellular uptake of transportan 10 and its analogs in live cells: Selectivity and structure-activity relationship studies Peptides 2011, 32 (9) 1934-1941 10.1016/j.peptides.2011.07.018
    • (2011) Peptides , vol.32 , Issue.9 , pp. 1934-1941
    • Song, J.1    Kai, M.2    Zhang, W.3    Zhang, J.4    Liu, L.5    Zhang, B.6    Liu, X.7    Wang, R.8
  • 59
    • 84922469442 scopus 로고    scopus 로고
    • Therapeutic applications of the cell-penetrating HIV-1 Tat peptide
    • Rizzuti, M.; Nizzardo, M.; Zanetta, C.; Ramirez, A.; Corti, S. Therapeutic applications of the cell-penetrating HIV-1 Tat peptide Drug Discovery Today 2015, 20 (1) 76-85 10.1016/j.drudis.2014.09.017
    • (2015) Drug Discovery Today , vol.20 , Issue.1 , pp. 76-85
    • Rizzuti, M.1    Nizzardo, M.2    Zanetta, C.3    Ramirez, A.4    Corti, S.5
  • 60
  • 61
    • 0038743278 scopus 로고    scopus 로고
    • In vitro uptake and stability study of pVEC and its all-D analog
    • Elmquist, A.; Langel, U. In vitro uptake and stability study of pVEC and its all-D analog Biol. Chem. 2003, 384 (3) 387-393 10.1515/BC.2003.044
    • (2003) Biol. Chem. , vol.384 , Issue.3 , pp. 387-393
    • Elmquist, A.1    Langel, U.2
  • 62
    • 34548162419 scopus 로고    scopus 로고
    • All-D proline-rich cellpenetrating peptides: A preliminary in vivo internalization study
    • Pujals, S.; Sabidó, E.; Tarragó, T.; Giralt, E. All-D proline-rich cellpenetrating peptides: a preliminary in vivo internalization study Biochem. Soc. Trans. 2007, 35 (4) 794-796 10.1042/BST0350794
    • (2007) Biochem. Soc. Trans. , vol.35 , Issue.4 , pp. 794-796
    • Pujals, S.1    Sabidó, E.2    Tarragó, T.3    Giralt, E.4
  • 63
    • 80052152968 scopus 로고    scopus 로고
    • Preferential Uptake of L- versus D-Amino Acid Cell-Penetrating Peptides in a Cell Type-Dependent Manner
    • Verdurmen, W. P.; Bovee-Geurts, P. H.; Wadhwani, P.; Ulrich, A. S.; Hällbrink, M.; van Kuppevelt, T. H.; Brock, R. Preferential Uptake of L- versus D-Amino Acid Cell-Penetrating Peptides in a Cell Type-Dependent Manner Chem. Biol. 2011, 18 (8) 1000-1010 10.1016/j.chembiol.2011.06.006
    • (2011) Chem. Biol. , vol.18 , Issue.8 , pp. 1000-1010
    • Verdurmen, W.P.1    Bovee-Geurts, P.H.2    Wadhwani, P.3    Ulrich, A.S.4    Hällbrink, M.5    Van Kuppevelt, T.H.6    Brock, R.7
  • 64
    • 84876536009 scopus 로고    scopus 로고
    • Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs
    • Montrose, K.; Yang, Y.; Sun, X.; Wiles, S.; Krissansen, G. W. Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs Sci. Rep. 2013, 3, 1661 10.1038/srep01661
    • (2013) Sci. Rep. , vol.3 , pp. 1661
    • Montrose, K.1    Yang, Y.2    Sun, X.3    Wiles, S.4    Krissansen, G.W.5
  • 65
    • 84861057424 scopus 로고    scopus 로고
    • Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug deliveryin vivo
    • Nakase, I.; Konishi, Y.; Ueda, M.; Saji, H.; Futaki, S. Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug deliveryin vivo J. Controlled Release 2012, 159 (2) 181-188 10.1016/j.jconrel.2012.01.016
    • (2012) J. Controlled Release , vol.159 , Issue.2 , pp. 181-188
    • Nakase, I.1    Konishi, Y.2    Ueda, M.3    Saji, H.4    Futaki, S.5
  • 66
    • 84902494466 scopus 로고    scopus 로고
    • Intercellular pH-responsive histidine modified dextran-g-cholesterol micelle for anticancer drug delivery
    • Yao, X.; Chen, L.; Chen, X.; He, C.; Zheng, H.; Chen, X. Intercellular pH-responsive histidine modified dextran-g-cholesterol micelle for anticancer drug delivery Colloids Surf., B 2014, 121, 36-43 10.1016/j.colsurfb.2014.05.032
    • (2014) Colloids Surf., B , vol.121 , pp. 36-43
    • Yao, X.1    Chen, L.2    Chen, X.3    He, C.4    Zheng, H.5    Chen, X.6
  • 67
    • 84870345946 scopus 로고    scopus 로고
    • The transfection activity of R8-modified nanoparticles and siRNA condensation using pH sensitive stearylated-octa histidine
    • Toriyabe, N.; Hayashi, Y.; Harashima, H. The transfection activity of R8-modified nanoparticles and siRNA condensation using pH sensitive stearylated-octa histidine Biomaterials 2013, 34, 1337-1343 10.1016/j.biomaterials.2012.10.043
    • (2013) Biomaterials , vol.34 , pp. 1337-1343
    • Toriyabe, N.1    Hayashi, Y.2    Harashima, H.3
  • 68
    • 84870354356 scopus 로고    scopus 로고
    • PH-sensitive poly(histidine)-PEG/DSPE-PEG co polymer micelles for cytosolic drug delivery
    • Wu, H.; Zhu, L.; Torchilin, V. P. pH-sensitive poly(histidine)-PEG/DSPE-PEG co polymer micelles for cytosolic drug delivery Biomaterials 2013, 34, 1213-1222 10.1016/j.biomaterials.2012.08.072
    • (2013) Biomaterials , vol.34 , pp. 1213-1222
    • Wu, H.1    Zhu, L.2    Torchilin, V.P.3
  • 69
    • 84863868920 scopus 로고    scopus 로고
    • Cancer nanomedicines targeting tumor extracellular pH
    • Tian, L.; Bae, Y. H. Cancer nanomedicines targeting tumor extracellular pH Colloids Surf., B 2012, 99, 116-126 10.1016/j.colsurfb.2011.10.039
    • (2012) Colloids Surf., B , vol.99 , pp. 116-126
    • Tian, L.1    Bae, Y.H.2
  • 70
    • 84865540257 scopus 로고    scopus 로고
    • Serum tolerance and endosomal escape capacity of histidine-modified pDNA-loaded complexes based on polyamidoamine dendrimer derivatives
    • Wen, Y.; Guo, Z.; Du, Z.; Fang, R.; Wu, H.; Zeng, X.; Wang, C.; Feng, M.; Pan, S. Serum tolerance and endosomal escape capacity of histidine-modified pDNA-loaded complexes based on polyamidoamine dendrimer derivatives Biomaterials 2012, 33 (32) 8111-8121 10.1016/j.biomaterials.2012.07.032
    • (2012) Biomaterials , vol.33 , Issue.32 , pp. 8111-8121
    • Wen, Y.1    Guo, Z.2    Du, Z.3    Fang, R.4    Wu, H.5    Zeng, X.6    Wang, C.7    Feng, M.8    Pan, S.9
  • 71
    • 84923312148 scopus 로고    scopus 로고
    • Suppression of VEGF by reversible-PEGylated histidylated polylysine in cancer therapy
    • Cai, X.; Zhu, H.; Dong, H.; Li, Y.; Su, J.; Shi, D. Suppression of VEGF by reversible-PEGylated histidylated polylysine in cancer therapy Adv. Healthcare Mater. 2014, 3 (11) 1818-1827 10.1002/adhm.201400063
    • (2014) Adv. Healthcare Mater. , vol.3 , Issue.11 , pp. 1818-1827
    • Cai, X.1    Zhu, H.2    Dong, H.3    Li, Y.4    Su, J.5    Shi, D.6
  • 72
    • 79960598683 scopus 로고    scopus 로고
    • Design of acid-activated cell penetrating peptide for delivery of active molecules into cancer cells
    • Zhang, W.; Song, J.; Zhang, B.; Liu, L.; Wang, K.; Wang, R. Design of acid-activated cell penetrating peptide for delivery of active molecules into cancer cells Bioconjugate Chem. 2011, 22, 1410-1415 10.1021/bc200138d
    • (2011) Bioconjugate Chem. , vol.22 , pp. 1410-1415
    • Zhang, W.1    Song, J.2    Zhang, B.3    Liu, L.4    Wang, K.5    Wang, R.6
  • 73
    • 84881026474 scopus 로고    scopus 로고
    • A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system
    • Zhang, Q.; Tang, J.; Fu, L.; Ran, R.; Liu, Y.; Yuan, M.; He, Q. A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system Biomaterials 2013, 34, 7980-7993 10.1016/j.biomaterials.2013.07.014
    • (2013) Biomaterials , vol.34 , pp. 7980-7993
    • Zhang, Q.1    Tang, J.2    Fu, L.3    Ran, R.4    Liu, Y.5    Yuan, M.6    He, Q.7
  • 74
    • 67650501109 scopus 로고    scopus 로고
    • Constructing bioactive peptides with pH dependent activities
    • Tu, Z.; Volk, M.; Shah, K.; Clerkin, K.; Liang, J. F. Constructing bioactive peptides with pH dependent activities Peptides 2009, 30, 1523-1528 10.1016/j.peptides.2009.05.009
    • (2009) Peptides , vol.30 , pp. 1523-1528
    • Tu, Z.1    Volk, M.2    Shah, K.3    Clerkin, K.4    Liang, J.F.5
  • 75
    • 71449112958 scopus 로고    scopus 로고
    • Design and characterization of an acid-activated antimicrobial peptide
    • Li, L.; He, J.; Eckert, R.; Yarbrough, D.; Lux, R.; Anderson, M.; Shi, W. Design and characterization of an acid-activated antimicrobial peptide Chem. Biol. Drug Des. 2010, 75, 127-132 10.1111/j.1747-0285.2009.00904.x
    • (2010) Chem. Biol. Drug Des. , vol.75 , pp. 127-132
    • Li, L.1    He, J.2    Eckert, R.3    Yarbrough, D.4    Lux, R.5    Anderson, M.6    Shi, W.7
  • 76
    • 65949122547 scopus 로고    scopus 로고
    • Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides
    • Makovitzki, A.; Fink, A.; Shai, Y. Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides Cancer Res. 2009, 69, 3458-3463 10.1158/0008-5472.CAN-08-3021
    • (2009) Cancer Res. , vol.69 , pp. 3458-3463
    • Makovitzki, A.1    Fink, A.2    Shai, Y.3
  • 77
    • 0032032440 scopus 로고    scopus 로고
    • Membrane permeabilization and efficient gene transfer by a peptide containing several histidines
    • Midoux, P.; Kichler, A.; Boutin, V.; Maurizot, J. C.; Monsigny, M. Membrane permeabilization and efficient gene transfer by a peptide containing several histidines Bioconjugate Chem. 1998, 9 (2) 260-267 10.1021/bc9701611
    • (1998) Bioconjugate Chem. , vol.9 , Issue.2 , pp. 260-267
    • Midoux, P.1    Kichler, A.2    Boutin, V.3    Maurizot, J.C.4    Monsigny, M.5
  • 78
    • 33646507124 scopus 로고    scopus 로고
    • Cationic amphipathic histidine-rich peptides for gene delivery
    • Kichler, A.; Mason, A. J.; Bechinger, B. Cationic amphipathic histidine-rich peptides for gene delivery Biochim. Biophys. Acta, Biomembr. 2006, 1758 (3) 301-317 10.1016/j.bbamem.2006.02.005
    • (2006) Biochim. Biophys. Acta, Biomembr. , vol.1758 , Issue.3 , pp. 301-317
    • Kichler, A.1    Mason, A.J.2    Bechinger, B.3
  • 79
    • 84884131045 scopus 로고    scopus 로고
    • Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery
    • Tanaka, K.; Kanazawa, T.; Horiuchi, S.; Ando, T.; Sugawara, K.; Takashima, Y.; Seta, Y.; Okada, H. Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery Int. J. Pharm. 2013, 455 (1-2) 40-47 10.1016/j.ijpharm.2013.07.069
    • (2013) Int. J. Pharm. , vol.455 , Issue.12 , pp. 40-47
    • Tanaka, K.1    Kanazawa, T.2    Horiuchi, S.3    Ando, T.4    Sugawara, K.5    Takashima, Y.6    Seta, Y.7    Okada, H.8
  • 80
    • 84867402736 scopus 로고    scopus 로고
    • Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery
    • Jiang, T.; Zhang, Z.; Zhang, Y.; Lv, H.; Zhou, J.; Li, C.; Hou, L.; Zhang, Q. Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery Biomaterials 2012, 33, 9246-9258 10.1016/j.biomaterials.2012.09.027
    • (2012) Biomaterials , vol.33 , pp. 9246-9258
    • Jiang, T.1    Zhang, Z.2    Zhang, Y.3    Lv, H.4    Zhou, J.5    Li, C.6    Hou, L.7    Zhang, Q.8
  • 81
    • 84855822879 scopus 로고    scopus 로고
    • The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel
    • Zhao, B. X.; Zhao, Y.; Huang, Y.; Luo, L. M.; Song, P.; Wang, X.; Chen, S.; Yu, K. F.; Zhang, X.; Zhang, Q. The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel Biomaterials 2012, 33, 2508-2520 10.1016/j.biomaterials.2011.11.078
    • (2012) Biomaterials , vol.33 , pp. 2508-2520
    • Zhao, B.X.1    Zhao, Y.2    Huang, Y.3    Luo, L.M.4    Song, P.5    Wang, X.6    Chen, S.7    Yu, K.F.8    Zhang, X.9    Zhang, Q.10
  • 82
    • 11144229887 scopus 로고    scopus 로고
    • Tumor imaging by means of proteolytic activation of cell-penetrating peptides
    • Jiang, T.; Olson, E. S.; Nguyen, Q. T.; Roy, M.; Jennings, P. A.; Tsien, R. Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides Proc. Natl. Acad. Sci. U. S. A. 2004, 101 (51) 17867-17872 10.1073/pnas.0408191101
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , Issue.51 , pp. 17867-17872
    • Jiang, T.1    Olson, E.S.2    Nguyen, Q.T.3    Roy, M.4    Jennings, P.A.5    Tsien, R.Y.6
  • 83
    • 77749335904 scopus 로고    scopus 로고
    • Systemic in vivo distribution of activatable cell penetrating peptides is superior to cell penetrating peptides
    • Aguilera, T. A.; Olson, E. S.; Timmers, M. M.; Jiang, T.; Tsien, R. Y. Systemic in vivo distribution of activatable cell penetrating peptides is superior to cell penetrating peptides Integr Biol. (Camb). 2009, 1 (5-6) 371-381 10.1039/b904878b
    • (2009) Integr Biol. (Camb). , vol.1 , Issue.56 , pp. 371-381
    • Aguilera, T.A.1    Olson, E.S.2    Timmers, M.M.3    Jiang, T.4    Tsien, R.Y.5
  • 84
    • 75949098347 scopus 로고    scopus 로고
    • In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer
    • Olson, E. S.; Aguilera, T. A.; Jiang, T.; Ellies, L. G.; Nguyen, Q. T.; Wong, E. H.; Gross, L. A.; Tsien, R. Y. In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer Integr Biol. (Camb). 2009, 1 (5-6) 382-393 10.1039/b904890a
    • (2009) Integr Biol. (Camb). , vol.1 , Issue.56 , pp. 382-393
    • Olson, E.S.1    Aguilera, T.A.2    Jiang, T.3    Ellies, L.G.4    Nguyen, Q.T.5    Wong, E.H.6    Gross, L.A.7    Tsien, R.Y.8
  • 85
    • 77749297971 scopus 로고    scopus 로고
    • Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
    • Olson, E. S.; Jiang, T.; Aguilera, T. A.; Nguyen, Q. T.; Ellies, L. G.; Scadeng, M.; Tsien, R. Y. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases Proc. Natl. Acad. Sci. U. S. A. 2010, 107 (9) 4311-4316 10.1073/pnas.0910283107
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , Issue.9 , pp. 4311-4316
    • Olson, E.S.1    Jiang, T.2    Aguilera, T.A.3    Nguyen, Q.T.4    Ellies, L.G.5    Scadeng, M.6    Tsien, R.Y.7
  • 86
    • 84875648834 scopus 로고    scopus 로고
    • Tumor-Targeting and Microenvironment-Responsive Smart Nanoparticles for Combination Therapy of Antiangiogenesis and Apoptosis
    • Huang, S.; Shao, K.; Liu, Y.; Kuang, Y.; Li, J.; An, S.; Guo, Y.; Ma, H.; Jiang, C. Tumor-Targeting and Microenvironment-Responsive Smart Nanoparticles for Combination Therapy of Antiangiogenesis and Apoptosis ACS Nano 2013, 7 (3) 2860-2871 10.1021/nn400548g
    • (2013) ACS Nano , vol.7 , Issue.3 , pp. 2860-2871
    • Huang, S.1    Shao, K.2    Liu, Y.3    Kuang, Y.4    Li, J.5    An, S.6    Guo, Y.7    Ma, H.8    Jiang, C.9
  • 87
    • 84905494071 scopus 로고    scopus 로고
    • Angiopep-2 and Activatable Cell-Penetrating Peptide DualFunctionalized Nanoparticles for Systemic Glioma-Targeting Delivery
    • Gao, H.; Zhang, S.; Cao, S.; Yang, Z.; Pang, Z.; Jiang, X. Angiopep-2 and Activatable Cell-Penetrating Peptide DualFunctionalized Nanoparticles for Systemic Glioma-Targeting Delivery Mol. Pharmaceutics 2014, 11 (8) 2755-2763 10.1021/mp500113p
    • (2014) Mol. Pharmaceutics , vol.11 , Issue.8 , pp. 2755-2763
    • Gao, H.1    Zhang, S.2    Cao, S.3    Yang, Z.4    Pang, Z.5    Jiang, X.6
  • 88
    • 84899893785 scopus 로고    scopus 로고
    • Imaging of MMP Activity in Postischemic Cardiac Remodeling Using Radiolabeled MMP-2/9 Activatable Peptide Probes
    • van Duijnhoven, S. M.; Robillard, M. S.; Hermann, S.; Kuhlmann, M. T.; Schäfers, M.; Nicolay, K.; Grüll, H. Imaging of MMP Activity in Postischemic Cardiac Remodeling Using Radiolabeled MMP-2/9 Activatable Peptide Probes Mol. Pharmaceutics 2014, 11 (5) 1415-1423 10.1021/mp400569k
    • (2014) Mol. Pharmaceutics , vol.11 , Issue.5 , pp. 1415-1423
    • Van Duijnhoven, S.M.1    Robillard, M.S.2    Hermann, S.3    Kuhlmann, M.T.4    Schäfers, M.5    Nicolay, K.6    Grüll, H.7
  • 89
    • 79851486239 scopus 로고    scopus 로고
    • Tumor targeting of MMP-2/9 activatable cell-penetrating imaging probes is caused by tumor-independent activation
    • van Duijnhoven, S. M.; Robillard, M. S.; Nicolay, K.; Grüll, H. Tumor targeting of MMP-2/9 activatable cell-penetrating imaging probes is caused by tumor-independent activation J. Nucl. Med. 2011, 52 (2) 279-286 10.2967/jnumed.110.082503
    • (2011) J. Nucl. Med. , vol.52 , Issue.2 , pp. 279-286
    • Van Duijnhoven, S.M.1    Robillard, M.S.2    Nicolay, K.3    Grüll, H.4
  • 90
    • 77749254873 scopus 로고    scopus 로고
    • Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
    • Nguyen, Q. T.; Olson, E. S.; Aguilera, T. A.; Jiang, T.; Scadeng, M.; Ellies, L. G.; Tsien, R. Y. Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival Proc. Natl. Acad. Sci. U. S. A. 2010, 107 (9) 4317-4322 10.1073/pnas.0910261107
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , Issue.9 , pp. 4317-4322
    • Nguyen, Q.T.1    Olson, E.S.2    Aguilera, T.A.3    Jiang, T.4    Scadeng, M.5    Ellies, L.G.6    Tsien, R.Y.7
  • 91
    • 84934959251 scopus 로고    scopus 로고
    • Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models
    • Metildi, C. A.; Felsen, C. N.; Savariar, E. N.; Nguyen, Q. T.; Kaushal, S.; Hoffman, R. M.; Tsien, R. Y.; Bouvet, M. Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models Ann. Surg Oncol. 2015, 22 (6) 2082-2087 10.1245/s10434-014-4144-1
    • (2015) Ann. Surg Oncol. , vol.22 , Issue.6 , pp. 2082-2087
    • Metildi, C.A.1    Felsen, C.N.2    Savariar, E.N.3    Nguyen, Q.T.4    Kaushal, S.5    Hoffman, R.M.6    Tsien, R.Y.7    Bouvet, M.8
  • 92
    • 84872560827 scopus 로고    scopus 로고
    • Real-time in Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides
    • Savariar, E. N.; Felsen, C. N.; Nashi, N.; Jiang, T.; Ellies, L. G.; Steinbach, P.; Tsien, R. Y.; Nguyen, Q. T. Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides Cancer Res. 2013, 73 (2) 855-864 10.1158/0008-5472.CAN-12-2969
    • (2013) Cancer Res. , vol.73 , Issue.2 , pp. 855-864
    • Savariar, E.N.1    Felsen, C.N.2    Nashi, N.3    Jiang, T.4    Ellies, L.G.5    Steinbach, P.6    Tsien, R.Y.7    Nguyen, Q.T.8
  • 93
    • 84867795473 scopus 로고    scopus 로고
    • Identification and Characterization of Receptor-Specific Peptides for siRNA Delivery
    • Ren, Y.; Hauert, S.; Lo, J. H.; Bhatia, S. N. Identification and Characterization of Receptor-Specific Peptides for siRNA Delivery ACS Nano 2012, 6 (10) 8620-8631 10.1021/nn301975s
    • (2012) ACS Nano , vol.6 , Issue.10 , pp. 8620-8631
    • Ren, Y.1    Hauert, S.2    Lo, J.H.3    Bhatia, S.N.4
  • 94
    • 84867751685 scopus 로고    scopus 로고
    • Rationally Designed Tumor-Penetrating Nanocomplexes
    • Karagiannis, E. D.; Alabi, C. A.; Anderson, D. G. Rationally Designed Tumor-Penetrating Nanocomplexes ACS Nano 2012, 6 (10) 8484-8487 10.1021/nn304707b
    • (2012) ACS Nano , vol.6 , Issue.10 , pp. 8484-8487
    • Karagiannis, E.D.1    Alabi, C.A.2    Anderson, D.G.3
  • 95
    • 84862807323 scopus 로고    scopus 로고
    • Target delivery of a gene into the brain using the RVG29-oligoarginine peptide
    • Gong, C.; Li, X.; Xu, L.; Zhang, Y. H. Target delivery of a gene into the brain using the RVG29-oligoarginine peptide Biomaterials 2012, 33 (12) 3456-3463 10.1016/j.biomaterials.2011.12.017
    • (2012) Biomaterials , vol.33 , Issue.12 , pp. 3456-3463
    • Gong, C.1    Li, X.2    Xu, L.3    Zhang, Y.H.4
  • 96
    • 84893229394 scopus 로고    scopus 로고
    • A Myristoylated Cell-Penetrating Peptide Bearing a Transferrin Receptor-Targeting Sequence for Neuro-Targeted siRNA Delivery
    • Youn, P.; Chen, Y.; Furgeson, D. Y. A Myristoylated Cell-Penetrating Peptide Bearing a Transferrin Receptor-Targeting Sequence for Neuro-Targeted siRNA Delivery Mol. Pharmaceutics 2014, 11 (2) 486-495 10.1021/mp400446v
    • (2014) Mol. Pharmaceutics , vol.11 , Issue.2 , pp. 486-495
    • Youn, P.1    Chen, Y.2    Furgeson, D.Y.3
  • 97
    • 84859439673 scopus 로고    scopus 로고
    • Peptides for cell-selective drug delivery
    • Svensen, N.; Walton, J. G.; Bradley, M. Peptides for cell-selective drug delivery Trends Pharmacol. Sci. 2012, 33 (4) 186-192 10.1016/j.tips.2012.02.002
    • (2012) Trends Pharmacol. Sci. , vol.33 , Issue.4 , pp. 186-192
    • Svensen, N.1    Walton, J.G.2    Bradley, M.3
  • 98
    • 38949104405 scopus 로고    scopus 로고
    • Design of a Tumor-Homing Cell-Penetrating Peptide
    • Myrberg, H.; Zhang, L.; Mäe, M.; Langel, U. Design of a Tumor-Homing Cell-Penetrating Peptide Bioconjugate Chem. 2008, 19 (1) 70-75 10.1021/bc0701139
    • (2008) Bioconjugate Chem. , vol.19 , Issue.1 , pp. 70-75
    • Myrberg, H.1    Zhang, L.2    Mäe, M.3    Langel, U.4
  • 99
    • 84896493907 scopus 로고    scopus 로고
    • Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting
    • Liu, Y.; Ran, R.; Chen, J.; Kuang, Q.; Tang, J.; Mei, L.; Zhang, Q.; Gao, H.; Zhang, Z.; He, Q. Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting Biomaterials 2014, 35 (17) 4835-4847 10.1016/j.biomaterials.2014.02.031
    • (2014) Biomaterials , vol.35 , Issue.17 , pp. 4835-4847
    • Liu, Y.1    Ran, R.2    Chen, J.3    Kuang, Q.4    Tang, J.5    Mei, L.6    Zhang, Q.7    Gao, H.8    Zhang, Z.9    He, Q.10
  • 100
    • 84904263868 scopus 로고    scopus 로고
    • RIPL peptide (IPLVVPLRRRRRRRRC)-conjugated liposomes for enhanced intracellular drug delivery to hepsin-expressing cancer cells
    • Kang, M. H.; Park, M. J.; Yoo, H. J.; Hyuk, K. Y.; Lee, S. G.; Kim, S. R.; Yeom, D. W.; Kang, M. J.; Choi, Y. W. RIPL peptide (IPLVVPLRRRRRRRRC)-conjugated liposomes for enhanced intracellular drug delivery to hepsin-expressing cancer cells Eur. J. Pharm. Biopharm. 2014, 87 (3) 489-499 10.1016/j.ejpb.2014.03.016
    • (2014) Eur. J. Pharm. Biopharm. , vol.87 , Issue.3 , pp. 489-499
    • Kang, M.H.1    Park, M.J.2    Yoo, H.J.3    Hyuk, K.Y.4    Lee, S.G.5    Kim, S.R.6    Yeom, D.W.7    Kang, M.J.8    Choi, Y.W.9
  • 101
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia, J. S.; Stan, R. V.; Dowdy, S. F. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis Nat. Med. 2004, 10, 310-315 10.1038/nm996
    • (2004) Nat. Med. , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 102
    • 84864114057 scopus 로고    scopus 로고
    • Synergistic effects of cell-penetrating peptide Tat and fusogenic peptide HA2-enhanced cellular internalization and gene transduction of organosilica nanoparticles
    • Ye, S. F.; Tian, M. M.; Wang, T. X.; Ren, L.; Wang, D.; Shen, L. H.; Shang, T. Synergistic effects of cell-penetrating peptide Tat and fusogenic peptide HA2-enhanced cellular internalization and gene transduction of organosilica nanoparticles Nanomedicine 2012, 8 (6) 833-841 10.1016/j.nano.2011.10.003
    • (2012) Nanomedicine , vol.8 , Issue.6 , pp. 833-841
    • Ye, S.F.1    Tian, M.M.2    Wang, T.X.3    Ren, L.4    Wang, D.5    Shen, L.H.6    Shang, T.7
  • 104
    • 65549133368 scopus 로고    scopus 로고
    • Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment
    • El-Sayed, A.; Futaki, S.; Harashima, H. Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment AAPS J. 2009, 11 (1) 13-22 10.1208/s12248-008-9071-2
    • (2009) AAPS J. , vol.11 , Issue.1 , pp. 13-22
    • El-Sayed, A.1    Futaki, S.2    Harashima, H.3
  • 105
    • 40649085520 scopus 로고    scopus 로고
    • An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection
    • Lo, S. L.; Wang, S. An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection Biomaterials 2008, 29 (15) 2408-2414 10.1016/j.biomaterials.2008.01.031
    • (2008) Biomaterials , vol.29 , Issue.15 , pp. 2408-2414
    • Lo, S.L.1    Wang, S.2
  • 108
    • 84912571365 scopus 로고    scopus 로고
    • Tumor homing cell penetrating peptide decorated nanoparticles used for enhancing tumor targeting delivery and therapy
    • Gao, H.; Zhang, Q.; Yang, Y.; Jiang, X.; He, Q. Tumor homing cell penetrating peptide decorated nanoparticles used for enhancing tumor targeting delivery and therapy Int. J. Pharm. 2015, 478 (1) 240-250 10.1016/j.ijpharm.2014.11.029
    • (2015) Int. J. Pharm. , vol.478 , Issue.1 , pp. 240-250
    • Gao, H.1    Zhang, Q.2    Yang, Y.3    Jiang, X.4    He, Q.5
  • 109
    • 84862674370 scopus 로고    scopus 로고
    • Cell entry of cell penetrating peptides: Tales of tails wagging dogs
    • Jones, A. T.; Sayers, E. J. Cell entry of cell penetrating peptides: tales of tails wagging dogs J. Controlled Release 2012, 161 (2) 582-591 10.1016/j.jconrel.2012.04.003
    • (2012) J. Controlled Release , vol.161 , Issue.2 , pp. 582-591
    • Jones, A.T.1    Sayers, E.J.2
  • 110
    • 34447282684 scopus 로고    scopus 로고
    • Melittin: A membrane-active peptide with diverse functions
    • Raghuraman, H.; Chattopadhyay, A. Melittin: a membrane-active peptide with diverse functions Biosci. Rep. 2007, 27 (4-5) 189-223 10.1007/s10540-006-9030-z
    • (2007) Biosci. Rep. , vol.27 , Issue.45 , pp. 189-223
    • Raghuraman, H.1    Chattopadhyay, A.2
  • 111
  • 112
    • 42149121346 scopus 로고    scopus 로고
    • Membrane-active peptides for non-viral gene therapy: Making the safest easier
    • Ferrer-Miralles, N.; Vázquez, E.; Villaverde, A. Membrane-active peptides for non-viral gene therapy: making the safest easier Trends Biotechnol. 2008, 26 (5) 267-275 10.1016/j.tibtech.2008.02.003
    • (2008) Trends Biotechnol. , vol.26 , Issue.5 , pp. 267-275
    • Ferrer-Miralles, N.1    Vázquez, E.2    Villaverde, A.3
  • 113
    • 33749385780 scopus 로고    scopus 로고
    • Cell-penetrating peptides and antimicrobial peptides: How different are they?
    • Henriques, S. T.; Melo, M. N.; Castanho, M. A. Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem. J. 2006, 399 (1) 1-7 10.1042/BJ20061100
    • (2006) Biochem. J. , vol.399 , Issue.1 , pp. 1-7
    • Henriques, S.T.1    Melo, M.N.2    Castanho, M.A.3
  • 114
    • 84857371360 scopus 로고    scopus 로고
    • Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation
    • Wadhwani, P.; Reichert, J.; Bürck, J.; Ulrich, A. S. Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation Eur. Biophys. J. 2012, 41 (2) 177-187 10.1007/s00249-011-0771-7
    • (2012) Eur. Biophys. J. , vol.41 , Issue.2 , pp. 177-187
    • Wadhwani, P.1    Reichert, J.2    Bürck, J.3    Ulrich, A.S.4
  • 115
    • 84919387496 scopus 로고    scopus 로고
    • Simultaneous delivery of therapeutic antagomirs with paclitaxel for the management of metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal delivery system
    • Zhang, Q.; Ran, R.; Zhang, L.; Liu, Y.; Mei, L.; Zhang, Z.; Gao, H.; He, Q. Simultaneous delivery of therapeutic antagomirs with paclitaxel for the management of metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal delivery system J. Controlled Release 2015, 197, 208-218 10.1016/j.jconrel.2014.11.010
    • (2015) J. Controlled Release , vol.197 , pp. 208-218
    • Zhang, Q.1    Ran, R.2    Zhang, L.3    Liu, Y.4    Mei, L.5    Zhang, Z.6    Gao, H.7    He, Q.8
  • 116
    • 84940784503 scopus 로고    scopus 로고
    • Development of an anti-microbial peptide-mediated liposomal delivery system: A novel approach towards pH-responsive anti-microbial peptides
    • Zhang, Q.; Tang, J.; Ran, R.; Liu, Y.; Zhang, Z.; Gao, H.; He, Q. Development of an anti-microbial peptide-mediated liposomal delivery system: a novel approach towards pH-responsive anti-microbial peptides Drug Delivery 2015, 19, 1-8 10.3109/10717544.2014.1003665
    • (2015) Drug Delivery , vol.19 , pp. 1-8
    • Zhang, Q.1    Tang, J.2    Ran, R.3    Liu, Y.4    Zhang, Z.5    Gao, H.6    He, Q.7
  • 117
    • 0023642299 scopus 로고
    • PH-dependent bilayer destabilization by an amphipathic peptide
    • Subbarao, N. K.; Parente, R. A.; Szoka, F. C., Jr.; Nadasdi, L.; Pongracz, K. pH-dependent bilayer destabilization by an amphipathic peptide Biochemistry 1987, 26 (11) 2964-2972 10.1021/bi00385a002
    • (1987) Biochemistry , vol.26 , Issue.11 , pp. 2964-2972
    • Subbarao, N.K.1    Parente, R.A.2    Szoka, Jr.F.C.3    Nadasdi, L.4    Pongracz, K.5
  • 118
    • 0023883581 scopus 로고
    • PH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide
    • Parente, R. A.; Nir, S.; Szoka, F. C., Jr. pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide J. Biol. Chem. 1988, 263 (10) 4724-4730
    • (1988) J. Biol. Chem. , vol.263 , Issue.10 , pp. 4724-4730
    • Parente, R.A.1    Nir, S.2    Szoka, Jr.F.C.3
  • 119
    • 1942438703 scopus 로고    scopus 로고
    • GALA: A designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery
    • Li, W.; Nicol, F.; Szoka, F. C., Jr. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery Adv. Drug Delivery Rev. 2004, 56 (7) 967-985 10.1016/j.addr.2003.10.041
    • (2004) Adv. Drug Delivery Rev. , vol.56 , Issue.7 , pp. 967-985
    • Li, W.1    Nicol, F.2    Szoka, Jr.F.C.3
  • 120
    • 2442421428 scopus 로고    scopus 로고
    • Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: An artificial viral-like delivery system
    • Kakudo, T.; Chaki, S.; Futaki, S.; Nakase, I.; Akaji, K.; Kawakami, T.; Maruyama, K.; Kamiya, H.; Harashima, H. Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system Biochemistry 2004, 43 (19) 5618-5628 10.1021/bi035802w
    • (2004) Biochemistry , vol.43 , Issue.19 , pp. 5618-5628
    • Kakudo, T.1    Chaki, S.2    Futaki, S.3    Nakase, I.4    Akaji, K.5    Kawakami, T.6    Maruyama, K.7    Kamiya, H.8    Harashima, H.9
  • 121
    • 49049118656 scopus 로고    scopus 로고
    • An artificial virus-like nano carrier system: Enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives
    • Sasaki, K.; Kogure, K.; Chaki, S.; Nakamura, Y.; Moriguchi, R.; Hamada, H.; Danev, R.; Nagayama, K.; Futaki, S.; Harashima, H. An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives Anal. Bioanal. Chem. 2008, 391 (8) 2717-2727 10.1007/s00216-008-2012-1
    • (2008) Anal. Bioanal. Chem. , vol.391 , Issue.8 , pp. 2717-2727
    • Sasaki, K.1    Kogure, K.2    Chaki, S.3    Nakamura, Y.4    Moriguchi, R.5    Hamada, H.6    Danev, R.7    Nagayama, K.8    Futaki, S.9    Harashima, H.10
  • 122
    • 69949155656 scopus 로고    scopus 로고
    • A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo
    • Hatakeyama, H.; Ito, E.; Akita, H.; Oishi, M.; Nagasaki, Y.; Futaki, S.; Harashima, H. A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo J. Controlled Release 2009, 139 (2) 127-132 10.1016/j.jconrel.2009.06.008
    • (2009) J. Controlled Release , vol.139 , Issue.2 , pp. 127-132
    • Hatakeyama, H.1    Ito, E.2    Akita, H.3    Oishi, M.4    Nagasaki, Y.5    Futaki, S.6    Harashima, H.7
  • 124
    • 79959900553 scopus 로고    scopus 로고
    • KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine
    • Shaheen, S. M.; Akita, H.; Nakamura, T.; Takayama, S.; Futaki, S.; Yamashita, A.; Katoono, R.; Yui, N.; Harashima, H. KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine Biomaterials 2011, 32 (26) 6342-6350 10.1016/j.biomaterials.2011.05.014
    • (2011) Biomaterials , vol.32 , Issue.26 , pp. 6342-6350
    • Shaheen, S.M.1    Akita, H.2    Nakamura, T.3    Takayama, S.4    Futaki, S.5    Yamashita, A.6    Katoono, R.7    Yui, N.8    Harashima, H.9
  • 125
    • 84878828057 scopus 로고    scopus 로고
    • A Recombinant Biopolymeric Platform for Reliable Evaluation of the Activity of pH-Responsive Amphiphile Fusogenic Peptides
    • Nouri, F. S.; Wang, X.; Dorrani, M.; Karjoo, Z.; Hatefi, A. A Recombinant Biopolymeric Platform for Reliable Evaluation of the Activity of pH-Responsive Amphiphile Fusogenic Peptides Biomacromolecules 2013, 14 (6) 2033-2040 10.1021/bm400380s
    • (2013) Biomacromolecules , vol.14 , Issue.6 , pp. 2033-2040
    • Nouri, F.S.1    Wang, X.2    Dorrani, M.3    Karjoo, Z.4    Hatefi, A.5
  • 127
    • 0030723767 scopus 로고    scopus 로고
    • Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix
    • Hunt, J. F.; Rath, P.; Rothschild, K. J.; Engelman, D. M. Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix Biochemistry 1997, 36 (49) 15177-15192 10.1021/bi970147b
    • (1997) Biochemistry , vol.36 , Issue.49 , pp. 15177-15192
    • Hunt, J.F.1    Rath, P.2    Rothschild, K.J.3    Engelman, D.M.4
  • 128
    • 78049333901 scopus 로고    scopus 로고
    • PH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents
    • Andreev, O. A.; Engelman, D. M.; Reshetnyak, Y. K. pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents Mol. Membr. Biol. 2010, 27 (7) 341-352 10.3109/09687688.2010.509285
    • (2010) Mol. Membr. Biol. , vol.27 , Issue.7 , pp. 341-352
    • Andreev, O.A.1    Engelman, D.M.2    Reshetnyak, Y.K.3
  • 134
    • 77749313553 scopus 로고    scopus 로고
    • Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP)
    • Andreev, O. A.; Engelman, D. M.; Reshetnyak, Y. K. Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP) Chim. Oggi 2009, 27 (2) 34-37
    • (2009) Chim. Oggi , vol.27 , Issue.2 , pp. 34-37
    • Andreev, O.A.1    Engelman, D.M.2    Reshetnyak, Y.K.3
  • 135
    • 84874933955 scopus 로고    scopus 로고
    • PHLIP®-mediated delivery of PEGylated liposomes to cancer cells
    • Yao, L.; Daniels, J.; Wijesinghe, D.; Andreev, O. A.; Reshetnyak, Y. K. pHLIP®-mediated delivery of PEGylated liposomes to cancer cells J. Controlled Release 2013, 167 (3) 228-237 10.1016/j.jconrel.2013.01.037
    • (2013) J. Controlled Release , vol.167 , Issue.3 , pp. 228-237
    • Yao, L.1    Daniels, J.2    Wijesinghe, D.3    Andreev, O.A.4    Reshetnyak, Y.K.5
  • 136
    • 84918781909 scopus 로고    scopus 로고
    • Targeting acidity in diseased tissues: Mechanism and applications of the membrane-inserting peptide, pHLIP
    • Deacon, J. C.; Engelman, D. M.; Barrera, F. N. Targeting acidity in diseased tissues: Mechanism and applications of the membrane-inserting peptide, pHLIP Arch. Biochem. Biophys. 2015, 565, 40-48 10.1016/j.abb.2014.11.002
    • (2015) Arch. Biochem. Biophys. , vol.565 , pp. 40-48
    • Deacon, J.C.1    Engelman, D.M.2    Barrera, F.N.3
  • 137
    • 70349482671 scopus 로고    scopus 로고
    • C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    • Teesalu, T.; Sugahara, K. N.; Kotamraju, V. R.; Ruoslahti, E. C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration Proc. Natl. Acad. Sci. U. S. A. 2009, 106 (38) 16157-16162 10.1073/pnas.0908201106
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , Issue.38 , pp. 16157-16162
    • Teesalu, T.1    Sugahara, K.N.2    Kotamraju, V.R.3    Ruoslahti, E.4
  • 138
    • 77955632888 scopus 로고    scopus 로고
    • Tumor-penetrating peptides: A shift from magic bullets to magic guns
    • Feron, O. Tumor-penetrating peptides: a shift from magic bullets to magic guns Sci. Transl. Med. 2010, 2 (34) 34ps26 10.1126/scitranslmed.3001174
    • (2010) Sci. Transl. Med. , vol.2 , Issue.34 , pp. 34ps26
    • Feron, O.1
  • 139
    • 77952901022 scopus 로고    scopus 로고
    • Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    • Sugahara, K. N.; Teesalu, T.; Karmali, P. P.; Kotamraju, V. R.; Agemy, L.; Greenwald, D. R.; Ruoslahti, E. Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs Science 2010, 328 (5981) 1031-1035 10.1126/science.1183057
    • (2010) Science , vol.328 , Issue.5981 , pp. 1031-1035
    • Sugahara, K.N.1    Teesalu, T.2    Karmali, P.P.3    Kotamraju, V.R.4    Agemy, L.5    Greenwald, D.R.6    Ruoslahti, E.7
  • 143
    • 84904727941 scopus 로고    scopus 로고
    • Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates
    • Wang, K.; Zhang, X.; Liu, Y.; Liu, C.; Jiang, B.; Jiang, Y. Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates Biomaterials 2014, 35 (30) 8735-8747 10.1016/j.biomaterials.2014.06.042
    • (2014) Biomaterials , vol.35 , Issue.30 , pp. 8735-8747
    • Wang, K.1    Zhang, X.2    Liu, Y.3    Liu, C.4    Jiang, B.5    Jiang, Y.6
  • 145
    • 84915792850 scopus 로고    scopus 로고
    • Targeting peptide iRGD-conjugated amphiphilic chitosan-co-PLA/DPPE drug delivery system for ennced tumor therapy
    • Zhao, C.; Liu, X.; Liu, J.; Yang, Z.; Rong, X.; Li, M.; Liang, X.; Wu, Y. Targeting peptide iRGD-conjugated amphiphilic chitosan-co-PLA/DPPE drug delivery system for ennced tumor therapy Colloids Surf., B 2014, 123, 787-796 10.1016/j.colsurfb.2014.10.024
    • (2014) Colloids Surf., B , vol.123 , pp. 787-796
    • Zhao, C.1    Liu, X.2    Liu, J.3    Yang, Z.4    Rong, X.5    Li, M.6    Liang, X.7    Wu, Y.8
  • 146
    • 84924857502 scopus 로고    scopus 로고
    • Doxorubicin-loaded polysaccharide nanoparticles suppress the growth of murine colorectal carcinoma and inhibit the metastasis of murine mammary carcinoma in rodent models
    • Li, M.; Tang, Z.; Zhang, D.; Sun, H.; Liu, H.; Zhang, Y.; Zhang, Y.; Chen, X. Doxorubicin-loaded polysaccharide nanoparticles suppress the growth of murine colorectal carcinoma and inhibit the metastasis of murine mammary carcinoma in rodent models Biomaterials 2015, 51, 161-172 10.1016/j.biomaterials.2015.02.002
    • (2015) Biomaterials , vol.51 , pp. 161-172
    • Li, M.1    Tang, Z.2    Zhang, D.3    Sun, H.4    Liu, H.5    Zhang, Y.6    Zhang, Y.7    Chen, X.8
  • 149
    • 84894428768 scopus 로고    scopus 로고
    • Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy
    • Wang, J.; Lei, Y.; Xie, C.; Lu, W.; Wagner, E.; Xie, Z.; Gao, J.; Zhang, X.; Yan, Z.; Liu, M. Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy Bioconjugate Chem. 2014, 25 (2) 414-423 10.1021/bc400552t
    • (2014) Bioconjugate Chem. , vol.25 , Issue.2 , pp. 414-423
    • Wang, J.1    Lei, Y.2    Xie, C.3    Lu, W.4    Wagner, E.5    Xie, Z.6    Gao, J.7    Zhang, X.8    Yan, Z.9    Liu, M.10
  • 151
  • 152
    • 84888319041 scopus 로고    scopus 로고
    • Targeted gene delivery to glioblastoma using a C-end rule RGERPPR peptide-functionalised polyethylenimine complex
    • Wang, J.; Lei, Y.; Xie, C.; Lu, W.; Yan, Z.; Gao, J.; Xie, Z.; Zhang, X.; Liu, M. Targeted gene delivery to glioblastoma using a C-end rule RGERPPR peptide-functionalised polyethylenimine complex Int. J. Pharm. 2013, 458 (1) 48-56 10.1016/j.ijpharm.2013.10.017
    • (2013) Int. J. Pharm. , vol.458 , Issue.1 , pp. 48-56
    • Wang, J.1    Lei, Y.2    Xie, C.3    Lu, W.4    Yan, Z.5    Gao, J.6    Xie, Z.7    Zhang, X.8    Liu, M.9
  • 154
    • 84877671384 scopus 로고    scopus 로고
    • Therapeutic potential of cell-penetrating peptides
    • Vasconcelos, L.; Pärn, K.; Langel, U. Therapeutic potential of cell-penetrating peptides Ther. Delivery 2013, 4 (5) 573-591 10.4155/tde.13.22
    • (2013) Ther. Delivery , vol.4 , Issue.5 , pp. 573-591
    • Vasconcelos, L.1    Pärn, K.2    Langel, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.