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Volumn 2, Issue 34, 2010, Pages

Tumor-penetrating peptides: A shift from magic bullets to magic guns

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOTENSIN II; ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; BRADYKININ; CD51 ANTIGEN; ENDOTHELIN; MONOCLONAL ANTIBODY; NANOPARTICLE; NEUROPILIN 1; NITRIC OXIDE; VASCULOTROPIN; VITRONECTIN RECEPTOR; ARGINYL-GLYCYL-ASPARTIC ACID; INTEGRIN; OLIGOPEPTIDE;

EID: 77955632888     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3001174     Document Type: Review
Times cited : (40)

References (37)
  • 2
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • J. S. Desgrosellier, D. A. Cheresh, Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer 10, 9-22 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 922
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 4
    • 0005306564 scopus 로고
    • Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor
    • D. A. Cheresh, Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. Proc. Natl. Acad. Sci. U.S.A. 84, 6471-6475 (1987).
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 6471-6475
    • Cheresh, D.A.1
  • 5
    • 0023609864 scopus 로고
    • Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion
    • M. D. Pierschbacher, E. Ruoslahti, Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion. J. Biol. Chem. 262, 17294-17298 (1987).
    • (1987) J. Biol. Chem. , vol.262 , pp. 17294-17298
    • Pierschbacher, M.D.1    Ruoslahti, E.2
  • 8
    • 70349482671 scopus 로고    scopus 로고
    • C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    • T. Teesalu, K. N. Sugahara, V. R. Kotamraju, E. Ruoslahti, C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc. Natl. Acad. Sci. U.S.A. 106, 16157-16162 (2009).
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 16157-16162
    • Teesalu, T.1    Sugahara, K.N.2    Kotamraju, V.R.3    Ruoslahti, E.4
  • 9
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • S. Soker, S. Takashima, H. Q. Miao, G. Neufeld, M. Klagsbrun, Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745 (1998).
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 10
    • 0034678343 scopus 로고    scopus 로고
    • Semaphorin3A enhances endocytosis at sites of receptor-F-actin colocalization during growth cone collapse
    • A. E. Fournier, F. Nakamura, S. Kawamoto, Y. Goshima, R. G. Kalb, S. M. Strittmatter, Semaphorin3A enhances endocytosis at sites of receptor-F-actin colocalization during growth cone collapse. J. Cell Biol. 149, 411-422 (2000).
    • (2000) J. Cell Biol. , vol.149 , pp. 411-422
    • Fournier, A.E.1    Nakamura, F.2    Kawamoto, S.3    Goshima, Y.4    Kalb, R.G.5    Strittmatter, S.M.6
  • 11
    • 33646552427 scopus 로고    scopus 로고
    • Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A
    • M. Narazaki, G. Tosato, Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood 107, 3892-3901 (2006).
    • (2006) Blood , vol.107 , pp. 3892-3901
    • Narazaki, M.1    Tosato, G.2
  • 13
    • 77955610033 scopus 로고    scopus 로고
    • note
    • Single-letter abbreviations for the amino acid residues are as follows: A, Ala; C, Cys; D, Asp; G, Gly; K, Lys; P, Pro; R, Arg.
  • 15
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Y. Matsumura, H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 46, 6387-6392 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 16
    • 34447103275 scopus 로고    scopus 로고
    • Targeting tumor stroma and exploiting mature tumor vasculature to improve anti-cancer drug delivery
    • C. Bouzin, O. Feron, Targeting tumor stroma and exploiting mature tumor vasculature to improve anti-cancer drug delivery. Drug Resist. Updat. 10, 109-120 (2007).
    • (2007) Drug Resist. Updat. , vol.10 , pp. 109-120
    • Bouzin, C.1    Feron, O.2
  • 18
    • 33746086723 scopus 로고    scopus 로고
    • Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery
    • P. Martinive, J. De Wever, C. Bouzin, C. Baudelet, P. Sonveaux, V. Grégoire, B. Gallez, O. Feron, Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery. Mol. Cancer Ther. 5, 1620-1627 (2006).
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1620-1627
    • Martinive, P.1    De Wever, J.2    Bouzin, C.3    Baudelet, C.4    Sonveaux, P.5    Grégoire, V.6    Gallez, B.7    Feron, O.8
  • 20
    • 0035146475 scopus 로고    scopus 로고
    • Bradykinin modulation of tumor vasculature: II. activation of nitric oxide and phospholipase A2/prostaglandin signaling pathways synergistically modifies vascular physiology and morphology to enhance delivery of chemotherapeutic agents to tumors
    • D. F. Emerich, R. L. Dean, P. Snodgrass, D. Lafreniere, M. Agostino, T. Wiens, H. Xiong, B. Hasler, J. Marsh, M. Pink, B. S. Kim, B. Perdomo, R. T. Bartus, Bradykinin modulation of tumor vasculature: II. activation of nitric oxide and phospholipase A2/prostaglandin signaling pathways synergistically modifies vascular physiology and morphology to enhance delivery of chemotherapeutic agents to tumors. J. Pharmacol. Exp. Ther. 296, 632-641 (2001).
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 632-641
    • Emerich, D.F.1    Dean, R.L.2    Snodgrass, P.3    Lafreniere, D.4    Agostino, M.5    Wiens, T.6    Xiong, H.7    Hasler, B.8    Marsh, J.9    Pink, M.10    Kim, B.S.11    Perdomo, B.12    Bartus, R.T.13
  • 21
    • 0027299899 scopus 로고
    • Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure
    • C. J. Li, Y. Miyamoto, Y. Kojima, H. Maeda, Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure. Br. J. Cancer 67, 975-980 (1993).
    • (1993) Br. J. Cancer , vol.67 , pp. 975-980
    • Li, C.J.1    Miyamoto, Y.2    Kojima, Y.3    Maeda, H.4
  • 22
    • 0019478990 scopus 로고
    • A new approach to cancer chemotherapy: Selective enhancement of tumor blood flow with angiotensin II
    • M. Suzuki, K. Hori, I. Abe, S. Saito, H. Sato, A new approach to cancer chemotherapy: Selective enhancement of tumor blood flow with angiotensin II. J. Natl. Cancer Inst. 67, 663-669 (1981).
    • (1981) J. Natl. Cancer Inst. , vol.67 , pp. 663-669
    • Suzuki, M.1    Hori, K.2    Abe, I.3    Saito, S.4    Sato, H.5
  • 25
    • 0032487348 scopus 로고    scopus 로고
    • Control of tumour vascular permeability
    • D. F. Baban, L. W. Seymour, Control of tumour vascular permeability. Adv. Drug Deliv. Rev. 34, 109-119 (1998).
    • (1998) Adv. Drug Deliv. Rev. , vol.34 , pp. 109-119
    • Baban, D.F.1    Seymour, L.W.2
  • 26
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • D. R. Senger, S. J. Galli, A. M. Dvorak, C. A. Perruzzi, V. S. Harvey, H. F. Dvorak, Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219, 983-985 (1983).
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 27
    • 0035074497 scopus 로고    scopus 로고
    • The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle
    • A. M. Dvorak, D. Feng, The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle. J. Histochem. Cytochem. 49, 419-432 (2001).
    • (2001) J. Histochem. Cytochem. , vol.49 , pp. 419-432
    • Dvorak, A.M.1    Feng, D.2
  • 28
    • 41949129114 scopus 로고    scopus 로고
    • Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor
    • L. M. Acevedo, S. Barillas, S. M. Weis, J. R. Göthert, D. A. Cheresh, Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood 111, 2674-2680 (2008).
    • (2008) Blood , vol.111 , pp. 2674-2680
    • Acevedo, L.M.1    Barillas, S.2    Weis, S.M.3    Göthert, J.R.4    Cheresh, D.A.5
  • 30
    • 0026334978 scopus 로고
    • Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells
    • C. L. Gladson, D. A. Cheresh, Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. J. Clin. Invest. 88, 1924-1932 (1991).
    • (1991) J. Clin. Invest. , vol.88 , pp. 1924-1932
    • Gladson, C.L.1    Cheresh, D.A.2
  • 31
    • 40249108222 scopus 로고    scopus 로고
    • Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition
    • M. Sarris, K. G. Andersen, F. Randow, L. Mayr, A. G. Betz, Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition. Immunity 28, 402-413 (2008).
    • (2008) Immunity , vol.28 , pp. 402-413
    • Sarris, M.1    Andersen, K.G.2    Randow, F.3    Mayr, L.4    Betz, A.G.5
  • 33
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • R. K. Jain, Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 307, 58-62 (2005).
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 34
    • 4544333732 scopus 로고    scopus 로고
    • Targeting the tumor vascular compartment to improve conventional cancer therapy
    • O. Feron, Targeting the tumor vascular compartment to improve conventional cancer therapy. Trends Pharmacol. Sci. 25, 536-542 (2004).
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 536-542
    • Feron, O.1
  • 36
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • J. M. Ebos, C. R. Lee, W. Cruz-Munoz, G. A. Bjarnason, J. G. Christensen, R. S. Kerbel, Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239 (2009).
    • (2009) Cancer Cell , vol.15 , pp. 232-239
    • Ebos, J.M.1    Lee, C.R.2    Cruz-Munoz, W.3    Bjarnason, G.A.4    Christensen, J.G.5    Kerbel, R.S.6
  • 37
    • 77955643345 scopus 로고    scopus 로고
    • note
    • Funding: O.F. is professor at the Université catholique de Louvain and Research Director of the Fonds de la Recherche Scientifi que (FRS-FNRS). His work is supported by grants from the FRS-FNRS, the Télévie, the Belgian Fundation Against Cancer, the J. Maisin Foundation, an Action de Recherche Concertée (ARC 09/14-020) from the Communauté Française de Belgique, the Région Bruxelles-Capitale, and the Région Wallonne. Competing interests: The author has no competing interests.


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