Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles

Journal of Controlled Release

Volumn 152, Issue 1, 2011, Pages 84-89

  Gao, Zhong Gao ^a,b   Tian, Li ^a   Hu, Jun ^a   Park, In Suh ^c   Bae, You Han ^a,d  

^a UNIVERSITY OF UTAH   (United States)

^b PEKING UNION MEDICAL COLLEGE   (China)

^c Inha University School of Medicine   (South Korea)

^d Utah Inha DDS and Advanced Theapeutics Research Center   (South Korea)

Author keywords

4T1 mammary carcinoma; Breast cancer; Folate; Metastasis model; pH sensitive micelle; Poly(l histidine b PEG)

Indexed keywords

BREAST CANCER; FOLATE; MAMMARY CARCINOMA; METASTASIS MODEL; PH SENSITIVE; POLY(L-HISTIDINE-B-PEG);

AMINO ACIDS; BIOLOGICAL ORGANS; BLOCK COPOLYMERS; CELL CULTURE; CONJUGATED POLYMERS; DISEASES; ENZYME INHIBITION; ETHYLENE; GLYCOLS; MAMMALS; MANGANESE; MICELLES; PATHOLOGY; POLYETHYLENE GLYCOLS; TUMORS;

POLYMERS;

DOXORUBICIN; FOLIC ACID; MACROGOL; PHOSPHATE BUFFERED SALINE; POLYHISTIDINE; POLYLACTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CARCINOGENESIS; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFICACY; FEMALE; HEART METASTASIS; LUNG METASTASIS; METASTASIS; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; TUMOR VOLUME; WEIGHT CHANGE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL PROLIFERATION; DOXORUBICIN; DRUG CARRIERS; FEMALE; FOLIC ACID; HYDROGEN-ION CONCENTRATION; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICELLES; NEOPLASM METASTASIS; POLYMERS;

EID: 79958164983     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.01.021     Document Type: Article

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