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Volumn 69, Issue 8, 2009, Pages 3458-3463

Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; LEUCYLHISTIDYLLEUCYLLEUCYLHISTIDYLHISTIDYLLEUCYLLEUCYLHISTIDYL HISTIDYLLEUCYLLEUCYLHISTIDYLLEUCYLLEUCINE; LEUCYLHISTIDYLLEUCYLLEUCYLHISTIDYLLYSYLLEUCYLLEUCYLLYSYL HISTIDYLLEUCYLLEUCYLLYSYLLEUCYLLEUCINE; LEUCYLLYSYLLEUCYLLEUCYLLYSYLLYSYLLEUCYLLEUCYLLYSYLLYSYLLEUCYLL EUCYLLYSYLLEUCYLLEUCINE; LYSINE; PEPTIDE DERIVATIVE; PROSTATE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

EID: 65949122547     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-3021     Document Type: Article
Times cited : (95)

References (52)
  • 1
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 1989; 49: 6449-65. (Pubitemid 20008770)
    • (1989) Cancer Research , vol.49 , Issue.23 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 2
    • 34648876684 scopus 로고    scopus 로고
    • Metabolic targeting as an anticancer strategy: Dawn of a new era?
    • Pan JG, Mak TW. Metabolic targeting as an anticancer strategy: dawn of a new era? Sci STKE 2007; 2007: pl4.
    • (2007) Sci STKE , vol.2007
    • Pan, J.G.1    Mak, T.W.2
  • 3
    • 0024379967 scopus 로고
    • Acid pH in tumors and its potential for therpeutic exploitation
    • Tannock IF, Kotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989; 49: 4373-84. (Pubitemid 19208329)
    • (1989) Cancer Research , vol.49 , Issue.16 , pp. 4373-4384
    • Tannock, I.F.1    Rotin, D.2
  • 4
    • 0020049348 scopus 로고
    • pH distributions in transplanted neural tumors and normal tissues of BDIX rats as measured with pH mieroelectrodes
    • Jahde E, Rajewsky MF, Baumgartl H, pH distributions in transplanted neural tumors and normal tissues of BDIX rats as measured with pH mieroelectrodes. Cancer Res 1982; 42: 1498-504.
    • (1982) Cancer Res. , vol.42 , pp. 1498-1504
    • Jahde, E.1    Rajewsky, M.F.2    Baumgartl, H.3
  • 5
    • 0028072842 scopus 로고
    • Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy
    • Martin GR, Jain RK. Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Cancer Res 1994; 54: 5670-4. (Pubitemid 24346265)
    • (1994) Cancer Research , vol.54 , Issue.21 , pp. 5670-5674
    • Martin, G.R.1    Jain, R.K.2
  • 7
    • 0021732164 scopus 로고
    • The relevance of tumour pH to the treatment of malignant disease
    • Wike-Hooley JL, Haveman J, Reinhold HS. The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 1984; 2: 343-66. (Pubitemid 15166545)
    • (1984) Radiotherapy and Oncology , vol.2 , Issue.4 , pp. 343-366
    • Wike-Hooley, J.L.1    Haveman, J.2    Reinhold, H.S.3
  • 8
    • 0842304934 scopus 로고    scopus 로고
    • A Prominent Low-pH Methotrexate Transport Activity in Human Solid Tumors: Contribution to the Preservation of Methotrexate Pharmacologic Activity in HeLa Cells Lacking the Reduced Folate Carrier
    • DOI 10.1158/1078-0432.CCR-1066-03
    • Zhao R, Gao F, Hanseorn M, Goldman ID. A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier. Clin. Cancer Res 2004; 10: 718-27. (Pubitemid 38180440)
    • (2004) Clinical Cancer Research , vol.10 , Issue.2 , pp. 718-727
    • Zhao, R.1    Gao, F.2    Hanscom, M.3    Goldman, I.D.4
  • 9
    • 4644224936 scopus 로고    scopus 로고
    • Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier
    • DOI 10.1158/1078-0432.CCR-04-0645
    • Wang Y, Zhao R, Goldman ID. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier. Clin. Cancer Res 2004; 10: 6256-64. (Pubitemid 39287534)
    • (2004) Clinical Cancer Research , vol.10 , Issue.18 , pp. 6256-6264
    • Wang, Y.1    Zhao, R.2    Goldman, I.D.3
  • 10
    • 0032788570 scopus 로고    scopus 로고
    • Acidic environment causes apoptosis by increasing caspase activity
    • DOI 10.1038/sj.bjc.6690617
    • Park HJ, Lyons JC, Ohtsubo T, Song CW. Acidic environment causes apoptosis by increasing caspase activity. Br J. Cancer 1999; 80: 1892-7. (Pubitemid 29391271)
    • (1999) British Journal of Cancer , vol.80 , Issue.12 , pp. 1892-1897
    • Park, H.J.1    Lyons, J.C.2    Ohtsubo, T.3    Song, C.W.4
  • 11
  • 12
    • 14644433029 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle
    • Lee ES, Na K, Bae YH. Super pH-sensitive multifunctional polymeric micelle. Nano Lett 2005; 5: 325-9.
    • (2005) Nano Lett , vol.5 , pp. 325-329
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 14
    • 0141921483 scopus 로고    scopus 로고
    • Polymeric micelle for tumor pH and folate-mediated targeting
    • DOI 10.1016/S0168-3659(03)00239-6
    • Lee ES, Na K, Bae YH. Polymeric micelle for tumor pH and folate-mediated targeting, J. Control Release 2003; 91: 103-13. (Pubitemid 37288881)
    • (2003) Journal of Controlled Release , vol.91 , Issue.1-2 , pp. 103-113
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 15
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • DOI 10.1038/415389a
    • Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002; 415: 389-95. (Pubitemid 34100944)
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1
  • 16
    • 33845699790 scopus 로고    scopus 로고
    • Antimicrobial and hostdefense peptides as new anti-infective therapeutic strategies
    • Hancock RE, Sahl HG. Antimicrobial and hostdefense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 2006; 24: 1551-7.
    • (2006) Nat Biotechnol , vol.24 , pp. 1551-1557
    • Hancock, R.E.1    Sahl, H.G.2
  • 17
    • 33746842648 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment
    • DOI 10.1517/13543784.15.8.933
    • Mader JS, Hoskin DW. Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment. Expert Opin Investig Drugs 2006; 15: 933-46. (Pubitemid 44177845)
    • (2006) Expert Opinion on Investigational Drugs , vol.15 , Issue.8 , pp. 933-946
    • Mader, J.S.1    Hoskin, D.W.2
  • 19
    • 36248993535 scopus 로고    scopus 로고
    • Antimicrobial peptides in oral cancer
    • DOI 10.2174/138161207782110372
    • Meyer JE, Harder J. Antimicrobial peptides in oral cancer. Curr Pharm Des 2007; 13: 3119-30. (Pubitemid 350130961)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.30 , pp. 3119-3130
    • Meyer, J.E.1    Harder, J.2
  • 20
    • 38349009178 scopus 로고    scopus 로고
    • Studies on anticancer activities of antimicrobial peptides
    • Hoskin DW, Ramamoorthy A. Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta 2008; 1778: 357-75.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 357-375
    • Hoskin, D.W.1    Ramamoorthy, A.2
  • 21
    • 18544366816 scopus 로고    scopus 로고
    • Host defense peptides as new weapons in cancer treatment
    • DOI 10.1007/s00018-005-4560-2
    • Papo N, Shai Y. Host defense peptides as new weapons in cancer treatment. Cell Mol. Life Sci 2005; 62: 784-90. (Pubitemid 40655628)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.7-8 , pp. 784-790
    • Papo, N.1    Shai, Y.2
  • 22
    • 4143110396 scopus 로고    scopus 로고
    • Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: Membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion
    • DOI 10.1158/0008-5472.CAN-04-1438
    • Papo N, Braunstein A, Eshhar Z, Shai Y. Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion. Cancer Res 2004; 64: 5779-86. (Pubitemid 39095578)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5779-5786
    • Papo, N.1    Braunstein, A.2    Eshhar, Z.3    Shai, Y.4
  • 23
    • 33744916273 scopus 로고    scopus 로고
    • Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide
    • DOI 10.1158/0008-5472.CAN-05-4569
    • Papo N, Seger D, Makovitzki A. et al. Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide. Cancer Res 2006; 66: 5371-8. (Pubitemid 43844963)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5371-5378
    • Papo, N.1    Seger, D.2    Makovitzki, A.3    Kalchenko, V.4    Eshhar, Z.5    Degani, H.6    Shai, Y.7
  • 24
    • 0033822710 scopus 로고    scopus 로고
    • CL1-GFP: An androgen independent metastatic tumor model for prostate cancer
    • Patel BJ, Pantuck AJ, Zisman A. et al. CL1-GFP: an androgen independent metastatic tumor model for prostate cancer. J. Urol 2000; 164: 1420-5.
    • (2000) J. Urol , vol.164 , pp. 1420-1425
    • Patel, B.J.1    Pantuck, A.J.2    Zisman, A.3
  • 26
    • 0018899158 scopus 로고
    • Serum-induced leakage of liposome contents
    • Allen TM, Cleland LG. Serum-induced leakage of liposome contents. Biochim Biophys Acta 1980; 597: 418-26. (Pubitemid 10066496)
    • (1980) Biochimica et Biophysica Acta , vol.597 , Issue.2 , pp. 418-426
    • Allen, T.M.1    Cleland, L.G.2
  • 28
    • 0031043059 scopus 로고    scopus 로고
    • Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
    • Zwaal RF, Schroit AJ. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood 1997; 89: 1121-32. (Pubitemid 27079974)
    • (1997) Blood , vol.89 , Issue.4 , pp. 1121-1132
    • Zwaal, R.F.A.1    Schroit, A.J.2
  • 29
    • 0042573730 scopus 로고    scopus 로고
    • New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells
    • DOI 10.1021/bi027212o
    • Papo N, Shai Y. New lytic peptides based on the d, L amphipathic helix motif preferentially kill tumor cells compared with normal cells. Biochemistry 2003; 42: 9346-54. (Pubitemid 36959242)
    • (2003) Biochemistry , vol.42 , Issue.31 , pp. 9346-9354
    • Papo, N.1    Shai, Y.2
  • 30
    • 0027179487 scopus 로고
    • Phospholipids in animal eukaryotic membranes: Transverse asymmetry and movement
    • Zachowski A. Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochem J. 1993; 294: 1-14. (Pubitemid 23251903)
    • (1993) Biochemical Journal , vol.294 , Issue.1 , pp. 1-14
    • Zachowski, A.1
  • 31
    • 33845373254 scopus 로고    scopus 로고
    • Anticancer α-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes
    • Dennison SR, Whittaker M, Harris F, Phoenix DA. Anticancer α-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes. Curr Protein Pept Sci 2006; 7: 487-99.
    • (2006) Curr Protein Pept Sci , vol.7 , pp. 487-499
    • Dennison, S.R.1    Whittaker, M.2    Harris, F.3    Phoenix, D.A.4
  • 32
    • 0025743796 scopus 로고
    • Elevated expression of phosphatidyl serine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes
    • Utsugi T, Schroit AJ, Connor J, Bueana CD, Fidler IJ. Elevated expression of phosphatidyl serine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes. Cancer Res 1991; 51: 3062-6.
    • (1991) Cancer Res. , vol.51 , pp. 3062-3066
    • Utsugi, T.1    Schroit, A.J.2    Connor, J.3    Bueana, C.D.4    Fidler, I.J.5
  • 34
    • 0032929589 scopus 로고    scopus 로고
    • I marcatori tumorali nella diagnosi del carcinoma pancreatico
    • Cappelli G, Paladini S, DAgata A. [Tumor markers in the diagnosis of pancreatic cancer], Tumori 1999; 85: S19-21. (Pubitemid 29213967)
    • (1999) Tumori , vol.85 , Issue.1 SUPPL. 1
    • Cappelli, G.1    Paladini, S.2    D'Agata, A.3
  • 35
    • 0030827120 scopus 로고    scopus 로고
    • Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell lines
    • DOI 10.1074/jbc.272.39.24198
    • Burdick MD, Harris A, Reid CJ, Iwamura T, Hollingsworth MA. Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell lines. J. Biol. Chem 1997: 272: 24198-202. (Pubitemid 27418619)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.39 , pp. 24198-24202
    • Burdick, M.D.1    Harris, A.2    Reid, C.J.3    Iwamura, T.4    Hollingsworth, M.A.5
  • 37
    • 0035967521 scopus 로고    scopus 로고
    • Membrane activity of the peptide antibiotic clavanin and the importance of its glycine residues
    • DOI 10.1021/bi0028136
    • van Kan EJ, van der Bent A, Demel RA, de Kruijff B. Membrane activity of the peptide antibiotic clavanin and the importance of its glycine residues. Biochemistry 2001; 40: 6398-405. (Pubitemid 32472729)
    • (2001) Biochemistry , vol.40 , Issue.21 , pp. 6398-6405
    • Van Kan, E.J.M.1    Van Der Bent, A.2    Demel, R.A.3    De Kruijff, B.4
  • 39
    • 9444251086 scopus 로고    scopus 로고
    • A new type of antimicrobial protein with multiple histidines from the hard tick
    • Lai R, Takeuchi H, Lomas LO. et al. A new type of antimicrobial protein with multiple histidines from the hard tick, Ambtyomma hebraeum. FASEB J. 2004; 18: 1447-9.
    • (2004) Ambtyomma hebraeum. FASEB J , vol.18 , pp. 1447-1449
    • Lai, R.1    Takeuchi, H.2    Lomas, L.O.3
  • 41
    • 0042510131 scopus 로고    scopus 로고
    • The role of the abundant phenylalanines in the mode of action of the antimicrobial peptide clavanin
    • DOI 10.1016/S0005-2736(03)00233-5
    • van Kan EJ, Demel RA, van der Bent A, de Kruijff B. The role of the abundant phenylalanines in the mode of action of the antimicrobial peptide clavanin. Biochim Biophys Acta 2003; 1615: 84-92. (Pubitemid 37013470)
    • (2003) Biochimica et Biophysica Acta - Biomembranes , vol.1615 , Issue.1-2 , pp. 84-92
    • Van Kan, E.J.M.1    Demel, R.A.2    Van Der Bent, A.3    De Kruijff, B.4
  • 42
    • 0037129944 scopus 로고    scopus 로고
    • Clavanin permeabilizes target membranes via two distinctly different pH-dependent mechanisms
    • DOI 10.1021/bi012162t
    • van Kan EJ, Demel RA, Breukink E, van der Bent A, de Kruijff B. Clavanin permeabilizes target membranes via two distinctly different pH-dependent mechanisms. Biochemistry 2002; 41: 7529-39. (Pubitemid 34627779)
    • (2002) Biochemistry , vol.41 , Issue.24 , pp. 7529-7539
    • Van Kan, E.J.M.1    Demel, R.A.2    Breukink, E.3    Van Der Bent, A.4    De Kruijff, B.5
  • 43
    • 33847051295 scopus 로고    scopus 로고
    • Effects of topology, length, and charge on the activity of a kininogen-derived peptide on lipid membranes and bacteria
    • DOI 10.1016/j.bbamem.2006.11.016, PII S0005273606004731
    • Ringstad L, Kacprzyk L, Schmidtchen A, Malmsten M. Effects of topology, length, and charge on the activity of a kininogen-derived peptide on lipid membranes and bacteria. Biochim Biophys Acta 2007; 1768: 715-27. (Pubitemid 46275597)
    • (2007) Biochimica et Biophysica Acta - Biomembranes , vol.1768 , Issue.3 , pp. 715-727
    • Ringstad, L.1    Kacprzyk, L.2    Schmidtchen, A.3    Malmsten, M.4
  • 44
    • 1842373858 scopus 로고    scopus 로고
    • Effects of pH and salinity on the antimicrobial properties of clavanins
    • Lee IH, Cho Y, Lehrer RI. Effects of pH and salinity on the antimicrobial properties of clavanins. Infect Immun 1997; 65: 2898-903. (Pubitemid 27264123)
    • (1997) Infection and Immunity , vol.65 , Issue.7 , pp. 2898-2903
    • Hee Lee, I.N.1    Cho, Y.2    Lehrer, R.I.3
  • 46
    • 22244489401 scopus 로고    scopus 로고
    • pH-dependent antifungal lipopeptides and their plausible mode of action
    • DOI 10.1021/bi0502386
    • Makovitzki A, Shai Y. pH-dependent antifungal lipopeptides and their plausible mode of action. Biochemistry 2005; 44: 9775-84. (Pubitemid 40994371)
    • (2005) Biochemistry , vol.44 , Issue.28 , pp. 9775-9784
    • Makovitzki, A.1    Shai, Y.2
  • 47
    • 0032849898 scopus 로고    scopus 로고
    • The interactions of histidine-containing amphipathic helical peptide antibiotics with lipid bilayers. The effects of charges and pH
    • DOI 10.1074/jbc.274.41.29115
    • Vogt TC, Bechinger B. The interactions of histidinecontaining amphipathic helical peptide antibiotics with lipid bilayers. The effects of charges and pH. J. Biol. Chem 1999; 274: 29115-21. (Pubitemid 29477075)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.41 , pp. 29115-29121
    • Vogt, T.C.B.1    Bechinger, B.2
  • 48
    • 0035858327 scopus 로고    scopus 로고
    • N-isopropylacrylamide copolymers for the preparation of pH-sensitive liposomes and polymeric micelles
    • DOI 10.1016/S0168-3659(01)00263-2, PII S0168365901002632
    • Leroux J, Roux E, Le Garrec D, Hong K, Drummond DC. N-isopropylaerylamide copolymers for the preparation of pH-sensitive liposomes and polymeric micelles. J. Control Release 2001; 72: 71-84. (Pubitemid 32522345)
    • (2001) Journal of Controlled Release , vol.72 , Issue.1-3 , pp. 71-84
    • Leroux, J.-C.1    Roux, E.2    Le Garrec, D.3    Hong, K.4    Drummond, D.C.5
  • 49
    • 33646507124 scopus 로고    scopus 로고
    • Cationic amphipathic histidine-rich peptides for gene delivery
    • Kichler A, Mason AJ, Bechinger B. Cationic amphipathic histidine-rich peptides for gene delivery. Biochim Biophys Acta 2006; 1758: 301-7.
    • (2006) Biochim Biophys Acta , vol.1758 , pp. 301-307
    • Kichler, A.1    Mason, A.J.2    Bechinger, B.3
  • 50
    • 0028933794 scopus 로고
    • Peptide antibiotics and their role in innate immunity
    • Boman HG. Peptide antibiotics and their role in innate immunity. Annu Rev Immunol 1995; 13: 61-92.
    • (1995) Annu Rev Immunol , vol.13 , pp. 61-92
    • Boman, H.G.1
  • 51
    • 0036829110 scopus 로고    scopus 로고
    • Increased exposure of anionic phospholipids on the surface of tumor blood vessels
    • Ran S, Downes A, Thorpe PE. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res 2002; 62: 6132-40. (Pubitemid 35244462)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6132-6140
    • Ran, S.1    Downes, A.2    Thorpe, P.E.3
  • 52
    • 0036891466 scopus 로고    scopus 로고
    • Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy
    • DOI 10.1016/S0360-3016(02)03928-7, PII S0360301602039287
    • Ran S, Thorpe PE. Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy. Int J. Radiat Oncol Biol. Phys 2002; 54: 1479-84. (Pubitemid 35380052)
    • (2002) International Journal of Radiation Oncology Biology Physics , vol.54 , Issue.5 , pp. 1479-1484
    • Ran, S.1    Thorpe, P.E.2


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