-
1
-
-
34249949775
-
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo
-
Andreev OA, et al. (2007) Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo. Proc Natl Acad Sci USA 104(19):7893-7898.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.19
, pp. 7893-7898
-
-
Andreev, O.A.1
-
2
-
-
34848885103
-
A monomeric membrane peptide that lives in three worlds: In solution, attached to, and inserted across lipid bilayers
-
Reshetnyak YK, Segala M, Andreev OA, Engelman DM (2007) A monomeric membrane peptide that lives in three worlds: In solution, attached to, and inserted across lipid bilayers. Biophys J 93(7):2363-2372.
-
(2007)
Biophys J
, vol.93
, Issue.7
, pp. 2363-2372
-
-
Reshetnyak, Y.K.1
Segala, M.2
Andreev, O.A.3
Engelman, D.M.4
-
3
-
-
80054741747
-
Roles of carboxyl groups in the transmembrane insertion of peptides
-
Barrera FN, et al. (2011) Roles of carboxyl groups in the transmembrane insertion of peptides. J Mol Biol 413(2):359-371.
-
(2011)
J Mol Biol
, vol.413
, Issue.2
, pp. 359-371
-
-
Barrera, F.N.1
-
4
-
-
84855683946
-
Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP
-
Reshetnyak YK, et al. (2011) Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP. Mol Imaging Biol 13(6):1146-1156.
-
(2011)
Mol Imaging Biol
, vol.13
, Issue.6
, pp. 1146-1156
-
-
Reshetnyak, Y.K.1
-
5
-
-
66249099231
-
A novel technology for the imaging of acidic prostate tumors by positron emission tomography
-
Vavere AL, et al. (2009) A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer Res 69(10):4510-4516.
-
(2009)
Cancer Res
, vol.69
, Issue.10
, pp. 4510-4516
-
-
Vavere, A.L.1
-
6
-
-
84870434595
-
In vivo pH imaging with (99m) Tc-pHLIP
-
Macholl S, et al. (2012) In vivo pH imaging with (99m) Tc-pHLIP. Imaging 14(6):725-734.
-
(2012)
Imaging
, vol.14
, Issue.6
, pp. 725-734
-
-
Macholl, S.1
-
7
-
-
33646272211
-
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix
-
Reshetnyak YK, Andreev OA, Lehnert U, Engelman DM (2006) Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix. Proc Natl Acad Sci USA 103(17):6460-6465.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.17
, pp. 6460-6465
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Lehnert, U.3
Engelman, D.M.4
-
8
-
-
78650553199
-
PH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation
-
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM (2010) pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation. Proc Natl Acad Sci USA 107(47):20246-20250.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.47
, pp. 20246-20250
-
-
An, M.1
Wijesinghe, D.2
Andreev, O.A.3
Reshetnyak, Y.K.4
Engelman, D.M.5
-
9
-
-
81855190867
-
Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide
-
Wijesinghe D, Engelman DM, Andreev OA, Reshetnyak YK (2011) Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide. Biochemistry 50(47):10215-10222.
-
(2011)
Biochemistry
, vol.50
, Issue.47
, pp. 10215-10222
-
-
Wijesinghe, D.1
Engelman, D.M.2
Andreev, O.A.3
Reshetnyak, Y.K.4
-
10
-
-
84865125806
-
Efficient (18) F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation
-
Daumar P, et al. (2012) Efficient (18) F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjug Chem 23(8):1557-1566.
-
(2012)
Bioconjug Chem
, vol.23
, Issue.8
, pp. 1557-1566
-
-
Daumar, P.1
-
11
-
-
84872198010
-
PHLIP peptide targets nanogold particles to tumors
-
Yao L, et al. (2012) pHLIP peptide targets nanogold particles to tumors. Proc Natl Acad Sci USA 110(2):465-470.
-
(2012)
Proc Natl Acad Sci USA
, vol.110
, Issue.2
, pp. 465-470
-
-
Yao, L.1
-
12
-
-
77749233798
-
PH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path
-
Andreev OA, et al. (2010) pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path. Proc Natl Acad Sci USA 107(9):4081-4086.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.9
, pp. 4081-4086
-
-
Andreev, O.A.1
-
13
-
-
84859901776
-
Modulation of the pHLIP transmembrane helix insertion pathway
-
Karabadzhak AG, et al. (2012) Modulation of the pHLIP transmembrane helix insertion pathway. Biophys J 102(8):1846-1855.
-
(2012)
Biophys J
, vol.102
, Issue.8
, pp. 1846-1855
-
-
Karabadzhak, A.G.1
-
14
-
-
33144478298
-
Peptide hairpins with strand segments containing alpha-and beta-amino acid residues: Cross-strand aromatic interactions of facing Phe residues
-
Roy RS, et al. (2005) Peptide hairpins with strand segments containing alpha-and beta-amino acid residues: Cross-strand aromatic interactions of facing Phe residues. Biopolymers 80(6):787-799.
-
(2005)
Biopolymers
, vol.80
, Issue.6
, pp. 787-799
-
-
Roy, R.S.1
-
15
-
-
77953935500
-
Tumour hypoxia induces a metabolic shift causing acidosis: A common feature in cancer
-
Chiche J, Brahimi-Horn MC, Pouysségur J (2010) Tumour hypoxia induces a metabolic shift causing acidosis: A common feature in cancer. J Cell Mol Med 14(4):771-794.
-
(2010)
J Cell Mol Med
, vol.14
, Issue.4
, pp. 771-794
-
-
Chiche, J.1
Brahimi-Horn, M.C.2
Pouysségur, J.3
-
16
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg O, Wind F, Negelein E (1927) The metabolism of tumors in the body. J Gen Physiol 8(6):519-530.
-
(1927)
J Gen Physiol
, vol.8
, Issue.6
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
17
-
-
79952084540
-
The spatial organization of proton and lactate transport in a rat brain tumor
-
Grillon E, et al. (2011) The spatial organization of proton and lactate transport in a rat brain tumor. PLoS ONE 6(2):e17416.
-
(2011)
PLoS ONE
, vol.6
, Issue.2
-
-
Grillon, E.1
-
18
-
-
0022004281
-
Brain acidosis
-
Rehncrona S (1985) Brain acidosis. Ann Emerg Med 14(8):770-776.
-
(1985)
Ann Emerg Med
, vol.14
, Issue.8
, pp. 770-776
-
-
Rehncrona, S.1
-
20
-
-
33846562017
-
Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia
-
Ihnatko R, et al. (2006) Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia. Int J Oncol 29(4):1025-1033.
-
(2006)
Int J Oncol
, vol.29
, Issue.4
, pp. 1025-1033
-
-
Ihnatko, R.1
-
21
-
-
0029971428
-
Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer
-
Gerweck LE, Seetharaman K (1996) Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer. Cancer Res 56(6):1194-1198.
-
(1996)
Cancer Res
, vol.56
, Issue.6
, pp. 1194-1198
-
-
Gerweck, L.E.1
Seetharaman, K.2
-
22
-
-
0035874951
-
The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics
-
Kozin SV, Shkarin P, Gerweck LE (2001) The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics. Cancer Res 61(12):4740-4743.
-
(2001)
Cancer Res
, vol.61
, Issue.12
, pp. 4740-4743
-
-
Kozin, S.V.1
Shkarin, P.2
Gerweck, L.E.3
|