Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates

Frontiers in Microbiology

Volumn 6, Issue AUG, 2015, Pages

  Trindade, Marla ^a   van Zyl, Leonardo Joaquim ^a   Navarro Fernández, José ^a,b   Elrazak, Ahmed Abd ^a,c  

^a UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^b UNIVERSITY OF MURCIA   (Spain)

^c Mansoura University   (Egypt)

Author keywords

Drug discovery; Functional screening; Marine natural products; Metagenomics; Symbionts; Uncultured microbes

Indexed keywords

BRYOSTATIN; CALYCULIN A; POLYKETIDE; TERPENOID; TRABECTEDIN;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; BIOCATALYST; BIODIVERSITY; BIOFILM; BIOINFORMATICS; CELL DENSITY; ENZYME ACTIVITY; GENE CLUSTER; GENE LIBRARY; GENE SEQUENCE; GENETIC SCREENING; METAGENOMICS; MICROBIAL DIVERSITY; NONHUMAN; POLYMERASE CHAIN REACTION; PSEUDOMONAS FLUORESCENS; REVIEW;

EID: 84941002573     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00890     Document Type: Review

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