메뉴 건너뛰기




Volumn 14, Issue 5, 2012, Pages 1198-1209

A functional screen for recovery of 4′-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BIOLOGICAL PRODUCT; PEPTIDE SYNTHASE; PHOSPHOPANTETHEINYL TRANSFERASE; PHOSPHOTRANSFERASE; POLYKETIDE SYNTHASE;

EID: 84859988527     PISSN: 14622912     EISSN: 14622920     Source Type: Journal    
DOI: 10.1111/j.1462-2920.2012.02699.x     Document Type: Article
Times cited : (48)

References (42)
  • 1
    • 0037781843 scopus 로고    scopus 로고
    • Substrate specificity of the nonribosomal peptide synthetase PvdD from Pseudomonas aeruginosa
    • Ackerley, D.F., Caradoc-Davies, T.T., and Lamont, I.L. (2003) Substrate specificity of the nonribosomal peptide synthetase PvdD from Pseudomonas aeruginosa. J Bacteriol 185: 2848-2855.
    • (2003) J Bacteriol , vol.185 , pp. 2848-2855
    • Ackerley, D.F.1    Caradoc-Davies, T.T.2    Lamont, I.L.3
  • 2
    • 58149287683 scopus 로고    scopus 로고
    • In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites
    • Ansari, M.Z., Sharma, J., Gokhale, R.S., and Mohanty, D. (2008) In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites. BMC Bioinformatics 9: 454.
    • (2008) BMC Bioinformatics , vol.9 , pp. 454
    • Ansari, M.Z.1    Sharma, J.2    Gokhale, R.S.3    Mohanty, D.4
  • 3
    • 0036918754 scopus 로고    scopus 로고
    • Combinatorial glycosylation of glycopeptide antibiotics
    • Baltz, R.H. (2002) Combinatorial glycosylation of glycopeptide antibiotics. Chem Biol 9: 1268-1270.
    • (2002) Chem Biol , vol.9 , pp. 1268-1270
    • Baltz, R.H.1
  • 4
    • 77957774503 scopus 로고    scopus 로고
    • Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules
    • Banik, J.J., and Brady, S.F. (2010) Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules. Curr Opin Microbiol 13: 603-609.
    • (2010) Curr Opin Microbiol , vol.13 , pp. 603-609
    • Banik, J.J.1    Brady, S.F.2
  • 5
    • 1942537599 scopus 로고    scopus 로고
    • Genetic characterization of pcpS, encoding the multifunctional phosphopantetheinyl transferase of Pseudomonas aeruginosa
    • Barekzi, N., Joshi, S., Irwin, S., Ontl, T., and Schweizer, H.P. (2004) Genetic characterization of pcpS, encoding the multifunctional phosphopantetheinyl transferase of Pseudomonas aeruginosa. Microbiology 150: 795-803.
    • (2004) Microbiology , vol.150 , pp. 795-803
    • Barekzi, N.1    Joshi, S.2    Irwin, S.3    Ontl, T.4    Schweizer, H.P.5
  • 6
    • 34250220631 scopus 로고    scopus 로고
    • Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules
    • Brady, S.F. (2007) Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules. Nat Prot 2: 1297-1305.
    • (2007) Nat Prot , vol.2 , pp. 1297-1305
    • Brady, S.F.1
  • 7
    • 0035963668 scopus 로고    scopus 로고
    • Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA
    • Brady, S.F., Chao, C.J., Handelsman, J., and Clardy, J. (2001) Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA. Org Lett 28: 1981-1984.
    • (2001) Org Lett , vol.28 , pp. 1981-1984
    • Brady, S.F.1    Chao, C.J.2    Handelsman, J.3    Clardy, J.4
  • 8
    • 0037226538 scopus 로고    scopus 로고
    • Microcystin biosynthesis in planktothrix: genes, evolution, and manipulation
    • Christiansen, G., Fastner, J., Erhard, M., Börner, T., and Dittmann, E. (2003) Microcystin biosynthesis in planktothrix: genes, evolution, and manipulation. J Bacteriol 185: 564-572.
    • (2003) J Bacteriol , vol.185 , pp. 564-572
    • Christiansen, G.1    Fastner, J.2    Erhard, M.3    Börner, T.4    Dittmann, E.5
  • 9
    • 33845708150 scopus 로고    scopus 로고
    • New antibiotics from bacterial natural products
    • Clardy, J., Fischbach, M.A., and Walsh, C.T. (2006) New antibiotics from bacterial natural products. Nat Biotech 24: 1541-1550.
    • (2006) Nat Biotech , vol.24 , pp. 1541-1550
    • Clardy, J.1    Fischbach, M.A.2    Walsh, C.T.3
  • 10
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko, K.A., and Wanner, B.L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97: 6640-6645.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 11
    • 63849314526 scopus 로고    scopus 로고
    • A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans
    • von Döhren, H. (2009) A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans. Fungal Genet Biol 46: S45-S52.
    • (2009) Fungal Genet Biol , vol.46
    • von Döhren, H.1
  • 13
  • 14
    • 67650281479 scopus 로고    scopus 로고
    • Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting
    • Fisch, K.M., Gurgui, C., Heycke, N., van der Sar, S.A., Anderson, S.A., Webb, V.L., etal. (2009) Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting. Nat Chem Biol 5: 494-501.
    • (2009) Nat Chem Biol , vol.5 , pp. 494-501
    • Fisch, K.M.1    Gurgui, C.2    Heycke, N.3    van der Sar, S.A.4    Anderson, S.A.5    Webb, V.L.6
  • 15
    • 55849150893 scopus 로고    scopus 로고
    • A computational screen for type I polyketide synthases in metagenomics shotgun data
    • Foerstner, K.U., Doerks, T., Creevey, C.J., Doerks, A., and Bork, P. (2008) A computational screen for type I polyketide synthases in metagenomics shotgun data. PLoS ONE 3: e3515.
    • (2008) PLoS ONE , vol.3
    • Foerstner, K.U.1    Doerks, T.2    Creevey, C.J.3    Doerks, A.4    Bork, P.5
  • 17
    • 0030738431 scopus 로고    scopus 로고
    • Enterobactin biosynthesis in Escherichia coli: isochorismate lyase (EntB) is a bifunctional enzyme that is phosphopantetheinylated by EntD and then acylated by EntE using ATP and 2,3-dihydroxybenzoate
    • Gehring, A.M., Bradley, K.A., and Walsh, C.T. (1997) Enterobactin biosynthesis in Escherichia coli: isochorismate lyase (EntB) is a bifunctional enzyme that is phosphopantetheinylated by EntD and then acylated by EntE using ATP and 2, 3-dihydroxybenzoate. Biochemistry 36: 8495-8503.
    • (1997) Biochemistry , vol.36 , pp. 8495-8503
    • Gehring, A.M.1    Bradley, K.A.2    Walsh, C.T.3
  • 19
    • 37449031390 scopus 로고    scopus 로고
    • Comparative genomics of Streptomyces avermitilis, Streptomyces cattleya, Streptomyces maritimus and Kitasatospora aureofaciens using a Streptomyces coelicolor microarray system
    • Hsiao, N.H., and Kirby, R. (2008) Comparative genomics of Streptomyces avermitilis, Streptomyces cattleya, Streptomyces maritimus and Kitasatospora aureofaciens using a Streptomyces coelicolor microarray system. Antonie Van Leeuwenhoek 93: 1-25.
    • (2008) Antonie Van Leeuwenhoek , vol.93 , pp. 1-25
    • Hsiao, N.H.1    Kirby, R.2
  • 20
    • 0032849859 scopus 로고    scopus 로고
    • CAP3: a DNA sequence assembly program
    • Huang, X., and Madan, A. (1999) CAP3: a DNA sequence assembly program. Genome Res 9: 868-877.
    • (1999) Genome Res , vol.9 , pp. 868-877
    • Huang, X.1    Madan, A.2
  • 21
    • 0031662188 scopus 로고    scopus 로고
    • Impact of culture-independent studies on the emerging phylogenetic view of bacterial diversity
    • Hugenholtz, P., Goebel, B.M., and Pace, N.R. (1998) Impact of culture-independent studies on the emerging phylogenetic view of bacterial diversity. J Bacteriol 180: 4765-4774.
    • (1998) J Bacteriol , vol.180 , pp. 4765-4774
    • Hugenholtz, P.1    Goebel, B.M.2    Pace, N.R.3
  • 22
    • 1842560595 scopus 로고    scopus 로고
    • Tapping into microbial diversity
    • Keller, M., and Zengler, K. (2004) Tapping into microbial diversity. Nat Rev Microbiol 2: 141-150.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 141-150
    • Keller, M.1    Zengler, K.2
  • 23
    • 77954630177 scopus 로고    scopus 로고
    • Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR
    • Kim, J.H., Feng, Z., Bauer, J.D., Kallifidas, D., Calle, P.Y., and Brady, S.F. (2010) Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR. Biopolymers 93: 833-844.
    • (2010) Biopolymers , vol.93 , pp. 833-844
    • Kim, J.H.1    Feng, Z.2    Bauer, J.D.3    Kallifidas, D.4    Calle, P.Y.5    Brady, S.F.6
  • 25
    • 67650436176 scopus 로고    scopus 로고
    • Drug discovery and natural products: end of an era or an endless frontier?
    • Li, J.W.H., and Vederas, J.C. (2009) Drug discovery and natural products: end of an era or an endless frontier? Science 325: 161-165.
    • (2009) Science , vol.325 , pp. 161-165
    • Li, J.W.H.1    Vederas, J.C.2
  • 26
    • 64249155091 scopus 로고    scopus 로고
    • Nonribosomal peptide synthetases: mechanistic and structural aspects of essential domains
    • Marahiel, M.A., and Essen, L.O. (2009) Nonribosomal peptide synthetases: mechanistic and structural aspects of essential domains. Methods Enzymol 458: 337-351.
    • (2009) Methods Enzymol , vol.458 , pp. 337-351
    • Marahiel, M.A.1    Essen, L.O.2
  • 27
    • 13944259584 scopus 로고    scopus 로고
    • Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts
    • Martinez, A., Kolvek, S.J., Yip, C.L.T., Hopke, J., Brown, K.A., MacNeil, I.A., and Osburne, M.S. (2004) Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts. Appl Environ Microb 70: 2452-2463.
    • (2004) Appl Environ Microb , vol.70 , pp. 2452-2463
    • Martinez, A.1    Kolvek, S.J.2    Yip, C.L.T.3    Hopke, J.4    Brown, K.A.5    MacNeil, I.A.6    Osburne, M.S.7
  • 28
    • 0035868628 scopus 로고    scopus 로고
    • On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia
    • Moffitt, M.C., and Neilan, B.A. (2001) On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia. FEMS Microbiol Lett 196: 207-214.
    • (2001) FEMS Microbiol Lett , vol.196 , pp. 207-214
    • Moffitt, M.C.1    Neilan, B.A.2
  • 29
    • 0037118621 scopus 로고    scopus 로고
    • Functional characterization of 4′-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5
    • Mootz, H.D., Schörgendorfer, K., and Marahiel, M.A. (2002) Functional characterization of 4′-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. FEMS Microbiol Lett 213: 51-57.
    • (2002) FEMS Microbiol Lett , vol.213 , pp. 51-57
    • Mootz, H.D.1    Schörgendorfer, K.2    Marahiel, M.A.3
  • 30
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman, D.J., and Cragg, G.M. (2007) Natural products as sources of new drugs over the last 25 years. J Nat Prod 70: 461-477.
    • (2007) J Nat Prod , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 31
    • 77956767424 scopus 로고    scopus 로고
    • Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation
    • Osbourn, A. (2010) Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation. Trends Genet 26: 449-457.
    • (2010) Trends Genet , vol.26 , pp. 449-457
    • Osbourn, A.1
  • 32
    • 79957747744 scopus 로고    scopus 로고
    • Rapid and flexible biochemical assays for evaluating 4′-phosphopantetheinyl transferase activity
    • Owen, J.G., Copp, J.N., and Ackerley, D.F. (2011) Rapid and flexible biochemical assays for evaluating 4′-phosphopantetheinyl transferase activity. Biochem J 436: 709-717.
    • (2011) Biochem J , vol.436 , pp. 709-717
    • Owen, J.G.1    Copp, J.N.2    Ackerley, D.F.3
  • 33
    • 79955563999 scopus 로고    scopus 로고
    • Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic library
    • Parachin, N.S., and Gorwa-Grauslund, M.F. (2011) Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic library. Biotechnol Biofuels 4: 9.
    • (2011) Biotechnol Biofuels , vol.4 , pp. 9
    • Parachin, N.S.1    Gorwa-Grauslund, M.F.2
  • 34
    • 0242523909 scopus 로고    scopus 로고
    • The uncultured microbial majority
    • Rappé, M.S., and Giovannoni, S.J. (2003) The uncultured microbial majority. Ann Rev Microbiol 57: 369-394.
    • (2003) Ann Rev Microbiol , vol.57 , pp. 369-394
    • Rappé, M.S.1    Giovannoni, S.J.2
  • 35
    • 36649038371 scopus 로고    scopus 로고
    • Comparison of cyanopeptolin genes in Planktothrix, Microcystis, and Anabaena strains: evidence for independent evolution within each genus
    • Rounge, T.B., Rohrlack, T., Tooming-Klunderud, A., Kristensen, T., and Jakobsen, K.S. (2007) Comparison of cyanopeptolin genes in Planktothrix, Microcystis, and Anabaena strains: evidence for independent evolution within each genus. Appl Environ Microbiol 73: 7322-7330.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 7322-7330
    • Rounge, T.B.1    Rohrlack, T.2    Tooming-Klunderud, A.3    Kristensen, T.4    Jakobsen, K.S.5
  • 36
    • 0025863049 scopus 로고
    • Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine
    • Rusnak, F., Sakaitani, M., Drueckhammer, D., Reichert, J., and Walsh, C.T. (1991) Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine. Biochemistry 30: 2916-2927.
    • (1991) Biochemistry , vol.30 , pp. 2916-2927
    • Rusnak, F.1    Sakaitani, M.2    Drueckhammer, D.3    Reichert, J.4    Walsh, C.T.5
  • 37
    • 18744382447 scopus 로고    scopus 로고
    • Cultivation of globally distributed soil bacteria from phylogenetic lineages previously only detected in cultivation-independent surveys
    • Sait, M., Hugenholtz, P., and Janssen, P.H. (2002) Cultivation of globally distributed soil bacteria from phylogenetic lineages previously only detected in cultivation-independent surveys. Environ Microbiol 4: 654-666.
    • (2002) Environ Microbiol , vol.4 , pp. 654-666
    • Sait, M.1    Hugenholtz, P.2    Janssen, P.H.3
  • 38
    • 23744472955 scopus 로고    scopus 로고
    • Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissolute
    • Schirmer, A., Gadkari, R., Reeves, C.D., Ibrahim, F., DeLong, E.F., and Hutchinson, C.R. (2005) Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissolute. Appl Environ Microbiol 71: 4840-4849.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 4840-4849
    • Schirmer, A.1    Gadkari, R.2    Reeves, C.D.3    Ibrahim, F.4    DeLong, E.F.5    Hutchinson, C.R.6
  • 39
    • 34247881849 scopus 로고    scopus 로고
    • Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis
    • Takahashi, H., Kumagai, T., Kitani, K., Mori, M., Matoba, Y., and Sugiyama, M. (2007) Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis. J Biol Chem 282: 9073-9081.
    • (2007) J Biol Chem , vol.282 , pp. 9073-9081
    • Takahashi, H.1    Kumagai, T.2    Kitani, K.3    Mori, M.4    Matoba, Y.5    Sugiyama, M.6
  • 40
    • 70449727646 scopus 로고    scopus 로고
    • Functional metagenomics for enzyme discovery: challenges to efficient screening
    • Uchiyama, T., and Miyazaki, K. (2009) Functional metagenomics for enzyme discovery: challenges to efficient screening. Curr Opin Biotechnol 20: 616-622.
    • (2009) Curr Opin Biotechnol , vol.20 , pp. 616-622
    • Uchiyama, T.1    Miyazaki, K.2
  • 41
    • 27644508250 scopus 로고    scopus 로고
    • Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase
    • Yin, J., Straight, P.D., McLoughlin, S.M., Zhou, Z.A., Lin, J., Golan, D.E., etal. (2005) Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase. Proc Natl Acad Sci USA 102: 15815-15820.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15815-15820
    • Yin, J.1    Straight, P.D.2    McLoughlin, S.M.3    Zhou, Z.A.4    Lin, J.5    Golan, D.E.6
  • 42
    • 34347368946 scopus 로고    scopus 로고
    • Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases
    • Zhou, Z., Cironi, P., Lin, A.J., Xu, Y., Hrvatin, S., Golan, D.E., etal. (2007) Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases. ACS Chem Biol 2: 337-246.
    • (2007) ACS Chem Biol , vol.2 , pp. 337-246
    • Zhou, Z.1    Cironi, P.2    Lin, A.J.3    Xu, Y.4    Hrvatin, S.5    Golan, D.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.