Metagenomic gene discovery: How far have we moved into novel sequence space?

Biotechnology Journal

Volumn 4, Issue 12, 2009, Pages 1671-1683

  Tuffin, Marla ^a   Anderson, Dominique ^a   Heath, Cal ^a   Cowan, Don A ^a  

^a UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Community; Expression libraries; High throughput screening; Metagenomics

Indexed keywords

BIOCATALYTIC ACTIVITY; COMMUNITY; COMMUNITY EXPRESSION; GENE DISCOVERY; GENETIC DIVERSITY; GENETIC MATERIALS; GLYCOSYL HYDROLASES; HIGH-THROUGHPUT SCREENING; METAGENOMICS; NEW DIMENSIONS; NEW OPPORTUNITIES; NOVEL PROTEINS; PROTEIN SEQUENCES; PROTEIN STRUCTURES; SEQUENCE SPACE;

LIBRARIES;

PROTEINS;

ALCOHOL DEHYDROGENASE; AMYLASE; ANTIBIOTIC AGENT; CARBOXYLESTERASE; CELLULASE; ESTERASE; GENOMIC DNA; GLYCOSIDASE; INDIRUBIN; PALMITOYLPUTRESCINE; PROTEIN AMYM; PROTEIN ECX21941; TRIACYLGLYCEROL LIPASE; TURBOMYCIN; UNCLASSIFIED DRUG; VIOLACEIN; VIRUS PROTEIN; XYLAN ENDO 1,3 BETA XYLOSIDASE;

ANTIMICROBIAL ACTIVITY; BACTERIAL GENE; BIOINFORMATICS; CRYSTAL STRUCTURE; DATA MINING; DNA LIBRARY; DNA SEQUENCE; DRUG SCREENING; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE CLUSTER; GENE EXPRESSION; GENE ISOLATION; GENETIC MANIPULATION; METAGENOMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; UNINDEXED SEQUENCE;

BACTERIA; BACTERIAL PROTEINS; ENZYMES; ESCHERICHIA COLI; GENETIC ASSOCIATION STUDIES; GENOMIC LIBRARY; GENOMICS; METAGENOME; PHYLOGENY;

EID: 73849152593     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200900235     Document Type: Review

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