Single-base pair genome editing in human cells by using site-specific endonucleases

International Journal of Molecular Sciences

Volumn 16, Issue 9, 2015, Pages 21128-21137

  Ochiai, Hiroshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

CRISPR; Gene therapy; Genome editing; Programmable nucleases; Single base pair editing; Single nucleotide polymorphisms; TALEN; Zinc finger nuclease

Indexed keywords

CRISPR ASSOCIATED PROTEIN; OLIGODEOXYNUCLEOTIDE; RESTRICTION ENDONUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE; ENDONUCLEASE;

BASE MISPAIRING; DNA END JOINING REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; EXCISION; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ENGINEERING; GENOME EDITING; HUMAN; HUMAN CELL; NUCLEIC ACID BASE SUBSTITUTION; PLASMID; POLYMERASE CHAIN REACTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPOSON; BASE PAIRING; GENETIC PREDISPOSITION; GENOME-WIDE ASSOCIATION STUDY; HUMAN GENOME; METABOLISM; PROCEDURES;

BASE PAIRING; ENDONUCLEASES; GENETIC ENGINEERING; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84940994861     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160921128     Document Type: Review

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