HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter

Genome Research

Volumn 22, Issue 3, 2012, Pages 446-455

  Visser, Mijke ^a   Kayser, Manfred ^a   Palstra, Robert Jan ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOID ENHANCER FACTOR 1; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PROTEIN; PROTEIN HERC2; PROTEIN OCA2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HLTF; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENE LOCUS; GENETIC CONSERVATION; HETEROZYGOTE; HUMAN; HUMAN CELL; MELANOCYTE; PHENOTYPE; PIGMENTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REGULATORY SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SPECIES; TRANSCRIPTION REGULATION;

ALLELES; CELL LINE; CHROMATIN; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MELANOCYTES; MEMBRANE TRANSPORT PROTEINS; ORGAN SPECIFICITY; PIGMENTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 84857192750     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.128652.111     Document Type: Article

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