Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models

Journal of Biomolecular Screening

Volumn 18, Issue 5, 2013, Pages 522-533

  Peng, Jun ^a   Liu, Qiuyue ^a   Rao, Mahendra S ^a   Zeng, Xianmin ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

dopaminergic neurons; neuroprotective; parkinsonism; stem cells

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 AMINOBENZAMIDE; 7 NITROINDAZOLE; ACETYLCYSTEINE; AMANTADINE; EPIGALLOCATECHIN GALLATE; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NEUROPROTECTIVE AGENT; NEUROTROPHIC FACTOR; NICOTINE; PHENANTHRIDONE; RESVERATROL; ROLIPRAM; ROTENONE; SELEGILINE; TAURINE; THIOCTIC ACID; TOPIRAMATE; UNCLASSIFIED DRUG; ZONISAMIDE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

DOPAMINERGIC NEURONS; NEUROPROTECTIVE; PARKINSONISM; STEM CELLS;

1-METHYL-4-PHENYLPYRIDINIUM; ANTIPARKINSON AGENTS; CELL DIFFERENTIATION; CELLS, CULTURED; DOPAMINERGIC NEURONS; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICROARRAY ANALYSIS; MODELS, THEORETICAL; NEUROGENESIS; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE, SECONDARY; PLURIPOTENT STEM CELLS; ROTENONE;

EID: 84878205912     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112474468     Document Type: Article

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