Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation

Cytotherapy

Volumn 15, Issue 8, 2013, Pages 999-1010

  Liu, Qiuyue ^a   Pedersen, Oliver Z ^a   Peng, Jun ^a   Couture, Larry A ^b   Rao, Mahendra S ^c   Zeng, Xianmin ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b Bechman Research Institute   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Cell therapy; Dopaminergic neuron; GMP; Human pluripotent stem cells

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN 2; DOPAMINE; HEPATOCYTE NUCLEAR FACTOR 3BETA; PROTEIN; PROTEIN LMX1A; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; BMP2 PROTEIN, HUMAN; FOXA2 PROTEIN, HUMAN; LIM HOMEODOMAIN PROTEIN; LMX1A PROTEIN, HUMAN; SHH PROTEIN, HUMAN; TRANSCRIPTION FACTOR; GUANOSINE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL SURVIVAL; CELL TRANSPLANTATION; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FREEZE THAWING; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PLURIPOTENT STEM CELL; ANIMAL; BIOLOGICAL THERAPY; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CRYOPRESERVATION; CULTURE TECHNIQUE; CYTOLOGY; DRUG DEVELOPMENT; IMMUNOLOGY; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PROCEDURES; TRANSPLANTATION; CELL THERAPY; HUMAN PLURIPOTENT STEM CELLS; METHODOLOGY;

ACTIVINS; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; CRYOPRESERVATION; DOPAMINE; DOPAMINERGIC NEURONS; DRUG DISCOVERY; HEDGEHOG PROTEINS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LIM-HOMEODOMAIN PROTEINS; MALE; MICE; MICE, INBRED C57BL; NEUROGENESIS; PLURIPOTENT STEM CELLS; TRANSCRIPTION FACTORS;

CELL THERAPY; DOPAMINERGIC NEURON; GMP; HUMAN PLURIPOTENT STEM CELLS;

EID: 84893505433     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2013.03.006     Document Type: Article

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