Compounds with species and cell type specific toxicity identified in a 2000 compound drug screen of neural stem cells and rat mixed cortical neurons

NeuroToxicology

Volumn 45, Issue , 2014, Pages 192-200

  Malik, Nasir ^a   Efthymiou, Anastasia G ^a   Mather, Karly ^b   Chester, Nathaniel ^b   Wang, Xiantao ^a   Nath, Avindra ^b   Rao, Mahendra S ^a,c,d   Steiner, Joseph P ^b  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Q Therapeutics   (United States)

Author keywords

Cardiac glycosides; Neural stem cells; Neurotoxicity screening

Indexed keywords

ACRIFLAVINE; ACTINONIN; AMIODARONE; ASTEMIZOLE; BENZALKONIUM; BENZETHONIUM CHLORIDE; CELASTROL; CHLORHEXIDINE; CHLORMETHINE; CINCHONIDINE; COLCHICINE; DEQUALINIUM; DIGOXIN; EMBELIN; KYNURENIC ACID; LANATOSIDE; MYRICETIN; NEOSTIGMINE; NILUTAMIDE; NORCANTHARIDIN; PENTOSALEN; PIPERINE; PYRITHIONE; QUINIDINE; QUININE SULFATE; SANGUINARINE; THIOMERSAL; THYROXINE; TRIPTOLIDE; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL STRUCTURE; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SCREENING; FEASIBILITY STUDY; FETUS; HIGH THROUGHPUT SCREENING; NERVE CELL CULTURE; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; PLURIPOTENT STEM CELL; RAT; STEM CELL CULTURE; TOXICITY TESTING; ANIMAL; BRAIN CORTEX; CELL CULTURE; CELL DEATH; DOSE RESPONSE; DRUG EFFECTS; HUMAN; PROCEDURES;

RATTUS;

ANIMALS; ASTROCYTES; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NEURAL STEM CELLS; RATS; TOXICITY TESTS;

EID: 84909645730     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.10.007     Document Type: Article

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