메뉴 건너뛰기




Volumn 47, Issue , 2015, Pages 17-26

Repeated exposure to chlorpyrifos leads to prolonged impairments of axonal transport in the living rodent brain

Author keywords

Alzheimer's disease; Gulf War Illness; Manganese enhanced magnetic resonance imaging; Organophosphate; Pesticide

Indexed keywords

ACETYLCHOLINESTERASE; CHLORPYRIFOS; MANGANESE; CONTRAST MEDIUM; INSECTICIDE;

EID: 84936931441     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.01.002     Document Type: Article
Times cited : (51)

References (72)
  • 1
    • 3042688573 scopus 로고    scopus 로고
    • Organophosphorus ester-induced chronic neurotoxicity
    • Abou-Donia M.B. Organophosphorus ester-induced chronic neurotoxicity. Arch Environ Health 2003, 58:484-497.
    • (2003) Arch Environ Health , vol.58 , pp. 484-497
    • Abou-Donia, M.B.1
  • 3
    • 84861191441 scopus 로고    scopus 로고
    • A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation
    • Banks C.N., Lein P.J. A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation. Neurotoxicology 2012, 33:575-584.
    • (2012) Neurotoxicology , vol.33 , pp. 575-584
    • Banks, C.N.1    Lein, P.J.2
  • 4
    • 34547728323 scopus 로고    scopus 로고
    • Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI)
    • Bearer E.L., Falzone T.L., Zhang X., Biris O., Rasin A., Jacobs R.E. Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI). Neuroimage 2007, 37(Suppl. 1):S37-S46.
    • (2007) Neuroimage , vol.37 , pp. S37-S46
    • Bearer, E.L.1    Falzone, T.L.2    Zhang, X.3    Biris, O.4    Rasin, A.5    Jacobs, R.E.6
  • 5
    • 67349129763 scopus 로고    scopus 로고
    • Reward circuitry is perturbed in the absence of the serotonin transporter
    • Bearer E.L., Zhang X., Janvelyan D., Boulat B., Jacobs R.E. Reward circuitry is perturbed in the absence of the serotonin transporter. Neuroimage 2009, 46:1091-1104.
    • (2009) Neuroimage , vol.46 , pp. 1091-1104
    • Bearer, E.L.1    Zhang, X.2    Janvelyan, D.3    Boulat, B.4    Jacobs, R.E.5
  • 6
    • 79957985535 scopus 로고    scopus 로고
    • Organophosphate and carbamate insecticides
    • Elsevier Saunders, St. Louis, M.E. Peterson, P.A. Talcott (Eds.)
    • Blodgett D.J. Organophosphate and carbamate insecticides. Small animal toxicology 2006, 941-947. Elsevier Saunders, St. Louis. 2nd ed. M.E. Peterson, P.A. Talcott (Eds.).
    • (2006) Small animal toxicology , pp. 941-947
    • Blodgett, D.J.1
  • 7
    • 0026024329 scopus 로고
    • Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate
    • Bushnell P.J., Padilla S.S., Ward T., Pope C.N., Olszyk V.B. Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate. J Pharmacol Exp Ther 1991, 256:741-750.
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 741-750
    • Bushnell, P.J.1    Padilla, S.S.2    Ward, T.3    Pope, C.N.4    Olszyk, V.B.5
  • 9
    • 33644664469 scopus 로고    scopus 로고
    • Current issues in organophosphate toxicology
    • Costa L.G. Current issues in organophosphate toxicology. Clin Chim Acta 2006, 366:1-13.
    • (2006) Clin Chim Acta , vol.366 , pp. 1-13
    • Costa, L.G.1
  • 10
    • 37849052251 scopus 로고    scopus 로고
    • Age-related decrease in axonal transport measured by MR imaging in vivo
    • Cross D.J., Flexman J.A., Anzai Y., Maravilla K.R., Minoshima S. Age-related decrease in axonal transport measured by MR imaging in vivo. Neuroimage 2008, 39:915-926.
    • (2008) Neuroimage , vol.39 , pp. 915-926
    • Cross, D.J.1    Flexman, J.A.2    Anzai, Y.3    Maravilla, K.R.4    Minoshima, S.5
  • 12
    • 0021287357 scopus 로고
    • Manganese fluxes and manganese-dependent neurotransmitter release in presynaptic nerve endings isolated from rat brain
    • Drapeau P., Nachshen D.A. Manganese fluxes and manganese-dependent neurotransmitter release in presynaptic nerve endings isolated from rat brain. J Physiol 1984, 348:493-510.
    • (1984) J Physiol , vol.348 , pp. 493-510
    • Drapeau, P.1    Nachshen, D.A.2
  • 13
    • 33749398995 scopus 로고    scopus 로고
    • The genetics of axonal transport and axonal transport disorders
    • Duncan J.E., Goldstein L.S. The genetics of axonal transport and axonal transport disorders. PLoS Genet 2006, 2(9):e124.
    • (2006) PLoS Genet , vol.2 , Issue.9 , pp. e124
    • Duncan, J.E.1    Goldstein, L.S.2
  • 14
    • 0034760772 scopus 로고    scopus 로고
    • Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality
    • Duysen E.G., Li B., Xie W., Schopfer L.M., Anderson R.S., Broomfield C.A., et al. Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther 2001, 299:528-535.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 528-535
    • Duysen, E.G.1    Li, B.2    Xie, W.3    Schopfer, L.M.4    Anderson, R.S.5    Broomfield, C.A.6
  • 15
  • 16
    • 0035819856 scopus 로고    scopus 로고
    • Pesticide use in developing countries
    • Ecobichon D.J. Pesticide use in developing countries. Toxicology 2001, 160(1-3):27-33.
    • (2001) Toxicology , vol.160 , Issue.1-3 , pp. 27-33
    • Ecobichon, D.J.1
  • 17
    • 38949115211 scopus 로고    scopus 로고
    • Management of acute organophosphorus pesticide poisoning
    • Eddleston M., Buckley N.A., Eyer P., Dawson A.H. Management of acute organophosphorus pesticide poisoning. Lancet 2008, 371(9612):597-607.
    • (2008) Lancet , vol.371 , Issue.9612 , pp. 597-607
    • Eddleston, M.1    Buckley, N.A.2    Eyer, P.3    Dawson, A.H.4
  • 18
    • 84862789332 scopus 로고    scopus 로고
    • Deficits in axonal transport in hippocampal-based circuitry and the visual pathway in APP knock-out animals witnessed by manganese enhanced MRI
    • Gallagher J.J., Zhang X., Ziomek G.J., Jacobs R.E., Bearer E.L. Deficits in axonal transport in hippocampal-based circuitry and the visual pathway in APP knock-out animals witnessed by manganese enhanced MRI. Neuroimage 2012, 60(3):1856-1866.
    • (2012) Neuroimage , vol.60 , Issue.3 , pp. 1856-1866
    • Gallagher, J.J.1    Zhang, X.2    Ziomek, G.J.3    Jacobs, R.E.4    Bearer, E.L.5
  • 19
    • 33846025142 scopus 로고    scopus 로고
    • Chlorpyrifos, chlorpyrifos-oxon, and diisopropylfluorophosphate inhibit kinesin-dependent microtubule motility
    • Gearhart D.A., Sickles D.W., Buccafusco J.J., Prendergast M.A., Terry A.V. Chlorpyrifos, chlorpyrifos-oxon, and diisopropylfluorophosphate inhibit kinesin-dependent microtubule motility. Toxicol Appl Pharmacol 2007, 218:20-29.
    • (2007) Toxicol Appl Pharmacol , vol.218 , pp. 20-29
    • Gearhart, D.A.1    Sickles, D.W.2    Buccafusco, J.J.3    Prendergast, M.A.4    Terry, A.V.5
  • 20
    • 69249221265 scopus 로고    scopus 로고
    • Mass spectral characterization of organophosphate-labeled lysine in peptides
    • Grigoryan H., Li B., Xue W., Grigoryan M., Schopfer L.M., Lockridge O. Mass spectral characterization of organophosphate-labeled lysine in peptides. Anal Biochem 2009, 394(1):92-100.
    • (2009) Anal Biochem , vol.394 , Issue.1 , pp. 92-100
    • Grigoryan, H.1    Li, B.2    Xue, W.3    Grigoryan, M.4    Schopfer, L.M.5    Lockridge, O.6
  • 21
    • 70349247706 scopus 로고    scopus 로고
    • Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity
    • Grigoryan H., Lockridge O. Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity. Toxicol Appl Pharmacol 2009, 240(2):143-148.
    • (2009) Toxicol Appl Pharmacol , vol.240 , Issue.2 , pp. 143-148
    • Grigoryan, H.1    Lockridge, O.2
  • 22
    • 0032510714 scopus 로고    scopus 로고
    • Distances between the paxitaxel, colchicine and exchangeable GTP binding sites on tubulin
    • Han Y., Malak H., Chaudhary A.G., Chordia M.D., Kingston D.G.I., Bane S. Distances between the paxitaxel, colchicine and exchangeable GTP binding sites on tubulin. Biochemistry 1998, 37:6636-6644.
    • (1998) Biochemistry , vol.37 , pp. 6636-6644
    • Han, Y.1    Malak, H.2    Chaudhary, A.G.3    Chordia, M.D.4    Kingston, D.G.I.5    Bane, S.6
  • 23
  • 24
    • 0026328348 scopus 로고
    • Interactions of colchicine with tubulin
    • Hastie S.B. Interactions of colchicine with tubulin. Pharmacol Ther 1991, 51(3):377-401.
    • (1991) Pharmacol Ther , vol.51 , Issue.3 , pp. 377-401
    • Hastie, S.B.1
  • 25
    • 77952226981 scopus 로고    scopus 로고
    • Occupational exposure to pesticides increases the risk of incident AD: the Cache County study
    • Hayden K.M., Norton M.C., Darcey D., Ostbye T., Zandi P.P., Breitner J.C., et al. Occupational exposure to pesticides increases the risk of incident AD: the Cache County study. Neurology 2010, 74:1524-1530.
    • (2010) Neurology , vol.74 , pp. 1524-1530
    • Hayden, K.M.1    Norton, M.C.2    Darcey, D.3    Ostbye, T.4    Zandi, P.P.5    Breitner, J.C.6
  • 26
    • 33847174004 scopus 로고    scopus 로고
    • Non-cholinesterase mechanisms of central and peripheral neurotoxicity: muscarinic receptors and other targets
    • Elsevier, San Diego, CA, R.C. Gupta (Ed.)
    • Jett D.A., Lein P.J. Non-cholinesterase mechanisms of central and peripheral neurotoxicity: muscarinic receptors and other targets. Toxicology of organophosphate and carbamate compounds 2006, 233-246. Elsevier, San Diego, CA. R.C. Gupta (Ed.).
    • (2006) Toxicology of organophosphate and carbamate compounds , pp. 233-246
    • Jett, D.A.1    Lein, P.J.2
  • 27
    • 79551685829 scopus 로고    scopus 로고
    • Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents
    • Jiang W., Duysen E.G., Hansen H., Shlyakhtenko L., Schopfer L.M., Lockridge O. Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents. Toxicol Sci 2010, 115(1):183-193.
    • (2010) Toxicol Sci , vol.115 , Issue.1 , pp. 183-193
    • Jiang, W.1    Duysen, E.G.2    Hansen, H.3    Shlyakhtenko, L.4    Schopfer, L.M.5    Lockridge, O.6
  • 28
    • 3142781649 scopus 로고    scopus 로고
    • Association of pesticide exposure with neurologic dysfunction and disease
    • Kamel F., Hoppin J.A. Association of pesticide exposure with neurologic dysfunction and disease. Environ Health Perspect 2004, 112(9):950-958.
    • (2004) Environ Health Perspect , vol.112 , Issue.9 , pp. 950-958
    • Kamel, F.1    Hoppin, J.A.2
  • 29
    • 0014985780 scopus 로고
    • Effect of colchicine on axonal transport and morphology of retinal ganglion cells
    • Karlsson J.O., Hansson H.A., Sjöstrand J. Effect of colchicine on axonal transport and morphology of retinal ganglion cells. Z Zellforsch Mikrosk Anat 1971, 115(2):265-283.
    • (1971) Z Zellforsch Mikrosk Anat , vol.115 , Issue.2 , pp. 265-283
    • Karlsson, J.O.1    Hansson, H.A.2    Sjöstrand, J.3
  • 30
    • 79955481136 scopus 로고    scopus 로고
    • Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI
    • Kim J., Choi I.Y., Michaelis M.L., Lee P. Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI. Neuroimage 2011, 56:1286-1292.
    • (2011) Neuroimage , vol.56 , pp. 1286-1292
    • Kim, J.1    Choi, I.Y.2    Michaelis, M.L.3    Lee, P.4
  • 32
    • 84903994766 scopus 로고    scopus 로고
    • Axonal transport rate decreased at the onset of optic neuritis in EAE mice
    • Lin T.H., Kim J.H., Perez-Torres C., Chiang C.W., Trinkaus K., Cross A.H., et al. Axonal transport rate decreased at the onset of optic neuritis in EAE mice. Neuroimage 2014, 15(100):244-253.
    • (2014) Neuroimage , vol.15 , Issue.100 , pp. 244-253
    • Lin, T.H.1    Kim, J.H.2    Perez-Torres, C.3    Chiang, C.W.4    Trinkaus, K.5    Cross, A.H.6
  • 33
    • 0030963695 scopus 로고    scopus 로고
    • Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function
    • Lin Y.J., Koretsky A.P. Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function. Magn Reson Med 1997, 38:378-388.
    • (1997) Magn Reson Med , vol.38 , pp. 378-388
    • Lin, Y.J.1    Koretsky, A.P.2
  • 34
    • 33847786566 scopus 로고    scopus 로고
    • Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI)
    • Lu H., Xi Z.X., Gitajn L., Rea W., Yang Y., Stein E.A. Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI). Proc Natl Acad Sci U S A 2007, 104:2489-2494.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 2489-2494
    • Lu, H.1    Xi, Z.X.2    Gitajn, L.3    Rea, W.4    Yang, Y.5    Stein, E.A.6
  • 36
    • 0024599906 scopus 로고
    • Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils
    • Merritt J.E., Jacob R., Hallam T.J. Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils. J Biol Chem 1989, 264:1522-1527.
    • (1989) J Biol Chem , vol.264 , pp. 1522-1527
    • Merritt, J.E.1    Jacob, R.2    Hallam, T.J.3
  • 37
    • 77953026873 scopus 로고    scopus 로고
    • Repeated exposures to low-level chlorpyrifos results in impairments in sustained attention and increased impulsivity in rats
    • Middlemore-Risher M.L., Buccafusco J.J., Terry A.V. Repeated exposures to low-level chlorpyrifos results in impairments in sustained attention and increased impulsivity in rats. Neurotoxicol Teratol 2010, 32:415-424.
    • (2010) Neurotoxicol Teratol , vol.32 , pp. 415-424
    • Middlemore-Risher, M.L.1    Buccafusco, J.J.2    Terry, A.V.3
  • 38
    • 0027533281 scopus 로고
    • Automated detection of the intercommissural line for stereotactic localization of functional brain images
    • Minoshima S., Koeppe R.A., Mintun M.A., Berger K.L., Taylor S.F., Frey K.A., et al. Automated detection of the intercommissural line for stereotactic localization of functional brain images. J Nucl Med 1993, 34(2):322-329.
    • (1993) J Nucl Med , vol.34 , Issue.2 , pp. 322-329
    • Minoshima, S.1    Koeppe, R.A.2    Mintun, M.A.3    Berger, K.L.4    Taylor, S.F.5    Frey, K.A.6
  • 39
    • 0025210047 scopus 로고
    • Mn and Mg influxes through Ca channels of motor nerve terminals are prevented by verapamil in frogs
    • Narita K., Kawasaki F., Kita H. Mn and Mg influxes through Ca channels of motor nerve terminals are prevented by verapamil in frogs. Brain Res 1990, 510:289-295.
    • (1990) Brain Res , vol.510 , pp. 289-295
    • Narita, K.1    Kawasaki, F.2    Kita, H.3
  • 40
    • 0031784528 scopus 로고    scopus 로고
    • In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging
    • Pautler R.G., Silva A.C., Koretsky A.P. In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging. Magn Reson Med 1998, 40:740-748.
    • (1998) Magn Reson Med , vol.40 , pp. 740-748
    • Pautler, R.G.1    Silva, A.C.2    Koretsky, A.P.3
  • 41
    • 0036338284 scopus 로고    scopus 로고
    • Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging
    • Pautler R.G., Koretsky A.P. Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging. Neuroimage 2002, 16:441-448.
    • (2002) Neuroimage , vol.16 , pp. 441-448
    • Pautler, R.G.1    Koretsky, A.P.2
  • 42
    • 84905049627 scopus 로고    scopus 로고
    • Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds
    • Pereira E.F., Aracava Y., DeTolla L.J., Beecham E.J., Basinger G.W., Wakayama E.J., et al. Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds. J Pharmacol Exp Ther 2014, 350(2):313-321.
    • (2014) J Pharmacol Exp Ther , vol.350 , Issue.2 , pp. 313-321
    • Pereira, E.F.1    Aracava, Y.2    DeTolla, L.J.3    Beecham, E.J.4    Basinger, G.W.5    Wakayama, E.J.6
  • 43
    • 0033369584 scopus 로고    scopus 로고
    • Organophosphorus pesticides: do they all have the same mechanism of toxicity?
    • Pope C.N. Organophosphorus pesticides: do they all have the same mechanism of toxicity?. J Toxicol Environ Health B Crit Rev 1999, 2:161-181.
    • (1999) J Toxicol Environ Health B Crit Rev , vol.2 , pp. 161-181
    • Pope, C.N.1
  • 44
    • 17044371595 scopus 로고    scopus 로고
    • Pharmacology and toxicology of cholinesterase inhibitors: uses and misuses of a common mechanism of action
    • Pope C., Karanth S., Liu J. Pharmacology and toxicology of cholinesterase inhibitors: uses and misuses of a common mechanism of action. Environ Toxicol Pharmacol 2005, 12:433-446.
    • (2005) Environ Toxicol Pharmacol , vol.12 , pp. 433-446
    • Pope, C.1    Karanth, S.2    Liu, J.3
  • 46
    • 0018907346 scopus 로고
    • Inhibition of fast axoplasmic transport by delayed neurotoxic organophosphorus esters: a possible mode of action
    • Reichart B.L., Abou-Donia M.B. Inhibition of fast axoplasmic transport by delayed neurotoxic organophosphorus esters: a possible mode of action. Mol Pharmacol 1980, 17:56-60.
    • (1980) Mol Pharmacol , vol.17 , pp. 56-60
    • Reichart, B.L.1    Abou-Donia, M.B.2
  • 48
    • 0028946275 scopus 로고
    • Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature
    • Richardson R.J. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature. J Toxicol Environ Health 1995, 44:135-165.
    • (1995) J Toxicol Environ Health , vol.44 , pp. 135-165
    • Richardson, R.J.1
  • 49
    • 79952102339 scopus 로고    scopus 로고
    • Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure
    • Rohlman D.S., Anger W.K., Lein P.J. Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure. Neurotoxicology 2011, 32:268-276.
    • (2011) Neurotoxicology , vol.32 , pp. 268-276
    • Rohlman, D.S.1    Anger, W.K.2    Lein, P.J.3
  • 50
    • 84871307986 scopus 로고    scopus 로고
    • Neurobehavioral problems following low-level exposure to organophosphate pesticides: a systematic and meta-analytic review
    • Ross S.M., McManus I.C., Harrison V., Mason O. Neurobehavioral problems following low-level exposure to organophosphate pesticides: a systematic and meta-analytic review. Crit Rev Toxicol 2013, 43(1):21-44.
    • (2013) Crit Rev Toxicol , vol.43 , Issue.1 , pp. 21-44
    • Ross, S.M.1    McManus, I.C.2    Harrison, V.3    Mason, O.4
  • 51
    • 3242795972 scopus 로고    scopus 로고
    • Organophosphate poisoning
    • Rusyniak D.E., Nanagas K.A. Organophosphate poisoning. Sem Neurol 2004, 24:197-204.
    • (2004) Sem Neurol , vol.24 , pp. 197-204
    • Rusyniak, D.E.1    Nanagas, K.A.2
  • 52
    • 12344296675 scopus 로고    scopus 로고
    • Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations
    • Silva A.C., Lee J.H., Aoki I., Koretsky A.P. Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations. NMR Biomed 2004, 17:532-543.
    • (2004) NMR Biomed , vol.17 , pp. 532-543
    • Silva, A.C.1    Lee, J.H.2    Aoki, I.3    Koretsky, A.P.4
  • 53
    • 0028142012 scopus 로고
    • Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia
    • Sloot W.N., Gramsbergen J.B. Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia. Brain Res 1994, 657:124-132.
    • (1994) Brain Res , vol.657 , pp. 124-132
    • Sloot, W.N.1    Gramsbergen, J.B.2
  • 54
    • 34147161245 scopus 로고    scopus 로고
    • In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease
    • Smith K.D., Kallhoff V., Zheng H., Pautler R.G. In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease. Neuroimage 2007, 35:1401-1408.
    • (2007) Neuroimage , vol.35 , pp. 1401-1408
    • Smith, K.D.1    Kallhoff, V.2    Zheng, H.3    Pautler, R.G.4
  • 55
    • 79954583620 scopus 로고    scopus 로고
    • R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI
    • Smith K.D., Paylor R., Pautler R.G. R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI. Magn Reson Med 2011, 65:1423-1429.
    • (2011) Magn Reson Med , vol.65 , pp. 1423-1429
    • Smith, K.D.1    Paylor, R.2    Pautler, R.G.3
  • 56
    • 65349132962 scopus 로고    scopus 로고
    • Current opinion on the science of organophosphate pesticides and toxic stress: a systematic review
    • Soltaninejad K., Abdollahi M. Current opinion on the science of organophosphate pesticides and toxic stress: a systematic review. Med Sci Monit 2009, 15:RA75-RA90.
    • (2009) Med Sci Monit , vol.15 , pp. RA75-RA90
    • Soltaninejad, K.1    Abdollahi, M.2
  • 57
    • 33746355958 scopus 로고    scopus 로고
    • Axonal transport and Alzheimer's disease
    • Stokin G.B., Goldstein L.S. Axonal transport and Alzheimer's disease. Annu Rev Biochem 2006, 75:607-627.
    • (2006) Annu Rev Biochem , vol.75 , pp. 607-627
    • Stokin, G.B.1    Goldstein, L.S.2
  • 58
    • 33645965246 scopus 로고    scopus 로고
    • Evaluation of several clinical scoring tools in organophosphate poisoned patients
    • Sungurtekin H., Gurses E., Balci C. Evaluation of several clinical scoring tools in organophosphate poisoned patients. Clin Toxicol (Phila) 2006, 44:121-126.
    • (2006) Clin Toxicol (Phila) , vol.44 , pp. 121-126
    • Sungurtekin, H.1    Gurses, E.2    Balci, C.3
  • 59
    • 0031975292 scopus 로고    scopus 로고
    • Manganese transport in the neural circuit of rat CNS
    • Takeda A., Kodama Y., Ishiwatari S., Okada S. Manganese transport in the neural circuit of rat CNS. Brain Res Bull 1998, 45:149-152.
    • (1998) Brain Res Bull , vol.45 , pp. 149-152
    • Takeda, A.1    Kodama, Y.2    Ishiwatari, S.3    Okada, S.4
  • 60
    • 0037379972 scopus 로고    scopus 로고
    • Repeated, subthreshold exposures to chlorpyrifos in rats: hippocampal damage, impaired axonal transport and deficits in spatial learning
    • Terry A.V., Stone J.D., Buccafusco J.J., Sickles D.W., Prendergast M.A. Repeated, subthreshold exposures to chlorpyrifos in rats: hippocampal damage, impaired axonal transport and deficits in spatial learning. J Pharmacol Exp Ther 2003, 305:375-384.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 375-384
    • Terry, A.V.1    Stone, J.D.2    Buccafusco, J.J.3    Sickles, D.W.4    Prendergast, M.A.5
  • 61
    • 34548098919 scopus 로고    scopus 로고
    • Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing
    • Terry A.V., Gearhart D.A., Beck W.D., Truan J.N., Middlemore M.L., Williamson L.N., et al. Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing. J Pharmacol Exp Ther 2007, 322:1117-1128.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 1117-1128
    • Terry, A.V.1    Gearhart, D.A.2    Beck, W.D.3    Truan, J.N.4    Middlemore, M.L.5    Williamson, L.N.6
  • 62
    • 79851511497 scopus 로고    scopus 로고
    • Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function
    • Terry A.V., Buccafusco J.J., Gearhart D.A., Beck W.D., Middlemore-Risher M.L., Truan J.N., et al. Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function. Neuroscience 2011, 10(176):237-253.
    • (2011) Neuroscience , vol.10 , Issue.176 , pp. 237-253
    • Terry, A.V.1    Buccafusco, J.J.2    Gearhart, D.A.3    Beck, W.D.4    Middlemore-Risher, M.L.5    Truan, J.N.6
  • 63
    • 84859788265 scopus 로고    scopus 로고
    • Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms
    • Terry A.V. Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms. Pharmacol Ther 2012, 134:355-365.
    • (2012) Pharmacol Ther , vol.134 , pp. 355-365
    • Terry, A.V.1
  • 64
    • 84901440385 scopus 로고    scopus 로고
    • Repeated exposures to diisopropylfluorophosphate result in impairments of sustained attention and persistent alterations of inhibitory response control in rats
    • Terry A.V., Callahan P.M., Beck W.D., Vandenhuerk L., Sinha S., Bouchard K., et al. Repeated exposures to diisopropylfluorophosphate result in impairments of sustained attention and persistent alterations of inhibitory response control in rats. Neurotoxicol Teratol 2014, 44:18-29.
    • (2014) Neurotoxicol Teratol , vol.44 , pp. 18-29
    • Terry, A.V.1    Callahan, P.M.2    Beck, W.D.3    Vandenhuerk, L.4    Sinha, S.5    Bouchard, K.6
  • 66
    • 53549113613 scopus 로고    scopus 로고
    • Manganese-enhanced MRI of the rat visual pathway: Acute neural toxicity, contrast enhancement, axon resolution, axonal transport, and clearance of Mn2+
    • Thuen M., Berry M., Pedersen T.B., Goa P.E., Summerfield M., Haraldseth O., et al. Manganese-enhanced MRI of the rat visual pathway: Acute neural toxicity, contrast enhancement, axon resolution, axonal transport, and clearance of Mn2+. J Magn Reson Imaging 2008, 28:855-865.
    • (2008) J Magn Reson Imaging , vol.28 , pp. 855-865
    • Thuen, M.1    Berry, M.2    Pedersen, T.B.3    Goa, P.E.4    Summerfield, M.5    Haraldseth, O.6
  • 68
    • 84936964394 scopus 로고    scopus 로고
    • United Nations Mission to Investigate Allegations of the Use of Chemical Weapons in the Syrian Arab Republic. Report on the Alleged Use of Chemical Weapons in the Ghouta Area of Damascus on 21 August 2013.
    • United Nations Mission to Investigate Allegations of the Use of Chemical Weapons in the Syrian Arab Republic. Report on the Alleged Use of Chemical Weapons in the Ghouta Area of Damascus on 21 August 2013.
  • 69
    • 0034845549 scopus 로고    scopus 로고
    • Mapping of retinal projections in the living rat using high-resolution 3D gradient-echo MRI with Mn2+-induced contrast
    • Watanabe T., Michaelis T., Frahm J. Mapping of retinal projections in the living rat using high-resolution 3D gradient-echo MRI with Mn2+-induced contrast. Magn Reson Med 2001, 46:424-429.
    • (2001) Magn Reson Med , vol.46 , pp. 424-429
    • Watanabe, T.1    Michaelis, T.2    Frahm, J.3
  • 70
    • 84862627475 scopus 로고    scopus 로고
    • Repeated exposures to chlorpyrifos lead to spatial memory retrieval impairment and motor activity alteration
    • Yan C., Jiao L., Zhao J., Yang H., Peng S. Repeated exposures to chlorpyrifos lead to spatial memory retrieval impairment and motor activity alteration. Neurotoxicol Teratol 2012, 34(4):442-449.
    • (2012) Neurotoxicol Teratol , vol.34 , Issue.4 , pp. 442-449
    • Yan, C.1    Jiao, L.2    Zhao, J.3    Yang, H.4    Peng, S.5
  • 72
    • 77955401360 scopus 로고    scopus 로고
    • Altered neurocircuitry in the dopamine transporter knockout mouse brain
    • Zhang X., Bearer E.L., Boulat B., Hall F.S., Uhl G.R., Jacobs R.E. Altered neurocircuitry in the dopamine transporter knockout mouse brain. PLoS ONE 2010, 5:e11506.
    • (2010) PLoS ONE , vol.5 , pp. e11506
    • Zhang, X.1    Bearer, E.L.2    Boulat, B.3    Hall, F.S.4    Uhl, G.R.5    Jacobs, R.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.