-
1
-
-
0035880229
-
Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
-
Barlogie B., Desikan R., Eddlemon P., Spencer T., Zeldis J., Munshi N., et al. Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood 2001, 98:492-494.
-
(2001)
Blood
, vol.98
, pp. 492-494
-
-
Barlogie, B.1
Desikan, R.2
Eddlemon, P.3
Spencer, T.4
Zeldis, J.5
Munshi, N.6
-
2
-
-
0027477946
-
Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
-
Beal M.F., Hyman B.T., Koroshetz W. Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?. Trends Neurosci 1993, 16:125-131.
-
(1993)
Trends Neurosci
, vol.16
, pp. 125-131
-
-
Beal, M.F.1
Hyman, B.T.2
Koroshetz, W.3
-
3
-
-
73649102801
-
Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science
-
Breier J.M., Gassmann K., Kayser R., Stegeman H., De Groot D., Fritsche E., et al. Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science. Neurotoxicol Teratol 2010, 32:4-15.
-
(2010)
Neurotoxicol Teratol
, vol.32
, pp. 4-15
-
-
Breier, J.M.1
Gassmann, K.2
Kayser, R.3
Stegeman, H.4
De Groot, D.5
Fritsche, E.6
-
4
-
-
49249113004
-
Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
-
Breier J.M., Radio N.M., Mundy W.R., Shafer T.J. Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicol Sci 2008, 105:119-133.
-
(2008)
Toxicol Sci
, vol.105
, pp. 119-133
-
-
Breier, J.M.1
Radio, N.M.2
Mundy, W.R.3
Shafer, T.J.4
-
5
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
Caiazzo M., Dell'Anno M.T., Dvoretskova E., Lazarevic D., Taverna S., Leo D., et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 2011, 476:224-227.
-
(2011)
Nature
, vol.476
, pp. 224-227
-
-
Caiazzo, M.1
Dell'Anno, M.T.2
Dvoretskova, E.3
Lazarevic, D.4
Taverna, S.5
Leo, D.6
-
6
-
-
37549042851
-
Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease
-
Ebert A.D., Beres A.J., Barber A.E., Svendsen C.N. Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease. Exp Neurol 2008, 209:213-223.
-
(2008)
Exp Neurol
, vol.209
, pp. 213-223
-
-
Ebert, A.D.1
Beres, A.J.2
Barber, A.E.3
Svendsen, C.N.4
-
8
-
-
0035129665
-
Prenatal exposure to methylmercury changes dopamine-modulated motor activity during early ontogeny: age and gender-dependent effects
-
Gimenez-Llort L., Ahlbom E., Dare E., Vahter M., Ogren S., Ceccatelli S. Prenatal exposure to methylmercury changes dopamine-modulated motor activity during early ontogeny: age and gender-dependent effects. Environ Toxicol Pharmacol 2001, 9:61-70.
-
(2001)
Environ Toxicol Pharmacol
, vol.9
, pp. 61-70
-
-
Gimenez-Llort, L.1
Ahlbom, E.2
Dare, E.3
Vahter, M.4
Ogren, S.5
Ceccatelli, S.6
-
9
-
-
12844272205
-
Methionine oxidation, alpha-synuclein and Parkinson's disease
-
Glaser C.B., Yamin G., Uversky V.N., Fink A.L. Methionine oxidation, alpha-synuclein and Parkinson's disease. Biochim Biophys Acta 2005, 1703:157-169.
-
(2005)
Biochim Biophys Acta
, vol.1703
, pp. 157-169
-
-
Glaser, C.B.1
Yamin, G.2
Uversky, V.N.3
Fink, A.L.4
-
10
-
-
15244348759
-
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
-
James S.J., Cutler P., Melnyk S., Jernigan S., Janak L., Gaylor D.W., et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr 2004, 80:1611-1617.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 1611-1617
-
-
James, S.J.1
Cutler, P.2
Melnyk, S.3
Jernigan, S.4
Janak, L.5
Gaylor, D.W.6
-
11
-
-
84862231907
-
Selective susceptibility of human dopaminergic neural stem cells to dopamine-induced apoptosis
-
Jeon S.M., Cheon S.M., Bae H.R., Kim J.W., Kim S.U. Selective susceptibility of human dopaminergic neural stem cells to dopamine-induced apoptosis. Exp Neurobiol 2010, 19:155-164.
-
(2010)
Exp Neurobiol
, vol.19
, pp. 155-164
-
-
Jeon, S.M.1
Cheon, S.M.2
Bae, H.R.3
Kim, J.W.4
Kim, S.U.5
-
12
-
-
33750608892
-
The pharmacokinetics of low-dose thalidomide in Japanese patients with refractory multiple myeloma
-
Kamikawa R., Ikawa K., Morikawa N., Asaoku H., Iwato K., Sasaki A. The pharmacokinetics of low-dose thalidomide in Japanese patients with refractory multiple myeloma. Biol Pharm Bull 2006, 29:2331-2334.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 2331-2334
-
-
Kamikawa, R.1
Ikawa, K.2
Morikawa, N.3
Asaoku, H.4
Iwato, K.5
Sasaki, A.6
-
13
-
-
79960983975
-
Thalidomide: the tragedy of birth defects and the effective treatment of disease
-
Kim J.H., Scialli A.R. Thalidomide: the tragedy of birth defects and the effective treatment of disease. Toxicol Sci 2011, 122:1-6.
-
(2011)
Toxicol Sci
, vol.122
, pp. 1-6
-
-
Kim, J.H.1
Scialli, A.R.2
-
14
-
-
84856279659
-
BDNF-, IGF-1- and GDNF-secreting human neural progenitor cells rescue amyloid beta-induced toxicity in cultured rat septal neurons
-
Kitiyanant N., Kitiyanant Y., Svendsen C.N., Thangnipon W. BDNF-, IGF-1- and GDNF-secreting human neural progenitor cells rescue amyloid beta-induced toxicity in cultured rat septal neurons. Neurochem Res 2011, 37:143-152.
-
(2011)
Neurochem Res
, vol.37
, pp. 143-152
-
-
Kitiyanant, N.1
Kitiyanant, Y.2
Svendsen, C.N.3
Thangnipon, W.4
-
15
-
-
61349192318
-
Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense
-
Knobloch J., Reimann K., Klotz L.O., Ruther U. Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense. Mol Pharm 2008, 5:1138-1144.
-
(2008)
Mol Pharm
, vol.5
, pp. 1138-1144
-
-
Knobloch, J.1
Reimann, K.2
Klotz, L.O.3
Ruther, U.4
-
16
-
-
37849052222
-
Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death
-
Knobloch J., Schmitz I., Gotz K., Schulze-Osthoff K., Ruther U. Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death. Mol Cell Biol 2008, 28:529-538.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 529-538
-
-
Knobloch, J.1
Schmitz, I.2
Gotz, K.3
Schulze-Osthoff, K.4
Ruther, U.5
-
17
-
-
67650770354
-
Capillary electrophoresis with electrospray ionization mass spectrometric detection for single-cell metabolomics
-
Lapainis T., Rubakhin S.S., Sweedler J.V. Capillary electrophoresis with electrospray ionization mass spectrometric detection for single-cell metabolomics. Anal Chem 2009, 81:5858-5864.
-
(2009)
Anal Chem
, vol.81
, pp. 5858-5864
-
-
Lapainis, T.1
Rubakhin, S.S.2
Sweedler, J.V.3
-
18
-
-
0023789803
-
A short history of thalidomide embryopathy
-
Lenz W. A short history of thalidomide embryopathy. Teratology 1988, 38:203-215.
-
(1988)
Teratology
, vol.38
, pp. 203-215
-
-
Lenz, W.1
-
19
-
-
80052579667
-
Stem cell technology for neurodegenerative diseases
-
Lunn J.S., Sakowski S.A., Hur J., Feldman E.L. Stem cell technology for neurodegenerative diseases. Ann Neurol 2011, 70:353-361.
-
(2011)
Ann Neurol
, vol.70
, pp. 353-361
-
-
Lunn, J.S.1
Sakowski, S.A.2
Hur, J.3
Feldman, E.L.4
-
20
-
-
83255189653
-
Dopamine cell transplantation in Parkinson's disease: challenge and perspective
-
Ma Y., Peng S., Dhawan V., Eidelberg D. Dopamine cell transplantation in Parkinson's disease: challenge and perspective. Br Med Bull 2011, 100:173-189.
-
(2011)
Br Med Bull
, vol.100
, pp. 173-189
-
-
Ma, Y.1
Peng, S.2
Dhawan, V.3
Eidelberg, D.4
-
21
-
-
68549089160
-
Metabolomics of neural progenitor cells: a novel approach to biomarker discovery
-
Maletic-Savatic M., Vingara L.K., Manganas L.N., Li Y., Zhang S., Sierra A., et al. Metabolomics of neural progenitor cells: a novel approach to biomarker discovery. Cold Spring Harb Symp Quant Biol 2008, 73:389-401.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 389-401
-
-
Maletic-Savatic, M.1
Vingara, L.K.2
Manganas, L.N.3
Li, Y.4
Zhang, S.5
Sierra, A.6
-
22
-
-
0037291745
-
Thalidomide: a review of approved and investigational uses
-
Matthews S.J., McCoy C. Thalidomide: a review of approved and investigational uses. Clin Ther 2003, 25:342-395.
-
(2003)
Clin Ther
, vol.25
, pp. 342-395
-
-
Matthews, S.J.1
McCoy, C.2
-
23
-
-
38349189124
-
Depiction of metabolome changes in histidine-starved Escherichia coli by CE-TOFMS
-
Ohashi Y., Hirayama A., Ishikawa T., Nakamura S., Shimizu K., Ueno Y., et al. Depiction of metabolome changes in histidine-starved Escherichia coli by CE-TOFMS. Mol Biosyst 2008, 4:135-147.
-
(2008)
Mol Biosyst
, vol.4
, pp. 135-147
-
-
Ohashi, Y.1
Hirayama, A.2
Ishikawa, T.3
Nakamura, S.4
Shimizu, K.5
Ueno, Y.6
-
24
-
-
84863229519
-
Effects of bisphenol A exposure on the proliferation and senescence of normal human mammary epithelial cells
-
Qin X.Y., Fukuda T., Yang L., Zaha H., Akanuma H., Zeng Q., et al. Effects of bisphenol A exposure on the proliferation and senescence of normal human mammary epithelial cells. Cancer Biol Ther 2012, 13:296-306.
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 296-306
-
-
Qin, X.Y.1
Fukuda, T.2
Yang, L.3
Zaha, H.4
Akanuma, H.5
Zeng, Q.6
-
25
-
-
84860534831
-
Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients
-
Qin X.Y., Kojima Y., Mizuno K., Ueoka K., Muroya K., Miyado M., et al. Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients. PLoS One 2012, 7:e36711.
-
(2012)
PLoS One
, vol.7
-
-
Qin, X.Y.1
Kojima, Y.2
Mizuno, K.3
Ueoka, K.4
Muroya, K.5
Miyado, M.6
-
26
-
-
80054072674
-
SiRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells
-
Qin X.Y., Wei F., Yoshinaga J., Yonemoto J., Tanokura M., Sone H. siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells. FEBS Lett 2011, 585:3310-3315.
-
(2011)
FEBS Lett
, vol.585
, pp. 3310-3315
-
-
Qin, X.Y.1
Wei, F.2
Yoshinaga, J.3
Yonemoto, J.4
Tanokura, M.5
Sone, H.6
-
27
-
-
74549156242
-
Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed AD brain
-
Ryu J.K., Cho T., Wang Y.T., McLarnon J.G. Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed AD brain. J Neuroinflamm 2009, 6:39.
-
(2009)
J Neuroinflamm
, vol.6
, pp. 39
-
-
Ryu, J.K.1
Cho, T.2
Wang, Y.T.3
McLarnon, J.G.4
-
28
-
-
49449109011
-
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease
-
Sanchez-Pernaute R., Lee H., Patterson M., Reske-Nielsen C., Yoshizaki T., Sonntag K.C., et al. Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain 2008, 131:2127-2139.
-
(2008)
Brain
, vol.131
, pp. 2127-2139
-
-
Sanchez-Pernaute, R.1
Lee, H.2
Patterson, M.3
Reske-Nielsen, C.4
Yoshizaki, T.5
Sonntag, K.C.6
-
29
-
-
84883833410
-
Thalidomide in the treatment of lepra reactions
-
Sheskin J. Thalidomide in the treatment of lepra reactions. Clin Pharmacol Ther 1965, 6:303-306.
-
(1965)
Clin Pharmacol Ther
, vol.6
, pp. 303-306
-
-
Sheskin, J.1
-
30
-
-
21244485072
-
Human motor neuron differentiation from human embryonic stem cells
-
Shin S., Dalton S., Stice S.L. Human motor neuron differentiation from human embryonic stem cells. Stem Cells Dev 2005, 14:266-269.
-
(2005)
Stem Cells Dev
, vol.14
, pp. 266-269
-
-
Shin, S.1
Dalton, S.2
Stice, S.L.3
-
31
-
-
0037093109
-
Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry
-
Soga T., Ueno Y., Naraoka H., Ohashi Y., Tomita M., Nishioka T. Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry. Anal Chem 2002, 74:2233-2239.
-
(2002)
Anal Chem
, vol.74
, pp. 2233-2239
-
-
Soga, T.1
Ueno, Y.2
Naraoka, H.3
Ohashi, Y.4
Tomita, M.5
Nishioka, T.6
-
32
-
-
77954744279
-
Prediction of metabolite identity from accurate mass, migration time prediction and isotopic pattern information in CE-TOFMS data
-
Sugimoto M., Hirayama A., Robert M., Abe S., Soga T., Tomita M. Prediction of metabolite identity from accurate mass, migration time prediction and isotopic pattern information in CE-TOFMS data. Electrophoresis 2010, 31:2311-2318.
-
(2010)
Electrophoresis
, vol.31
, pp. 2311-2318
-
-
Sugimoto, M.1
Hirayama, A.2
Robert, M.3
Abe, S.4
Soga, T.5
Tomita, M.6
-
33
-
-
77949297718
-
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles
-
Sugimoto M., Wong D.T., Hirayama A., Soga T., Tomita M. Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 2010, 6:78-95.
-
(2010)
Metabolomics
, vol.6
, pp. 78-95
-
-
Sugimoto, M.1
Wong, D.T.2
Hirayama, A.3
Soga, T.4
Tomita, M.5
-
34
-
-
79961209466
-
Protective effect of thalidomide against N-methyl-d-aspartate-induced retinal neurotoxicity
-
Takada K., Munemasa Y., Kuribayashi J., Fujino H., Kitaoka Y. Protective effect of thalidomide against N-methyl-d-aspartate-induced retinal neurotoxicity. J Neurosci Res 2011, 89:1596-1604.
-
(2011)
J Neurosci Res
, vol.89
, pp. 1596-1604
-
-
Takada, K.1
Munemasa, Y.2
Kuribayashi, J.3
Fujino, H.4
Kitaoka, Y.5
-
35
-
-
13844256192
-
Thalidomide as a novel therapeutic agent: new uses for an old product
-
Teo S.K., Stirling D.I., Zeldis J.B. Thalidomide as a novel therapeutic agent: new uses for an old product. Drug Discov Today 2005, 10:107-114.
-
(2005)
Drug Discov Today
, vol.10
, pp. 107-114
-
-
Teo, S.K.1
Stirling, D.I.2
Zeldis, J.B.3
-
36
-
-
33645469813
-
Thalidomide use in the US: experience with pregnancy testing in the S.T.E.P.S. programme
-
Uhl K., Cox E., Rogan R., Zeldis J.B., Hixon D., Furlong L.A., et al. Thalidomide use in the US: experience with pregnancy testing in the S.T.E.P.S. programme. Drug Saf 2006, 29:321-329.
-
(2006)
Drug Saf
, vol.29
, pp. 321-329
-
-
Uhl, K.1
Cox, E.2
Rogan, R.3
Zeldis, J.B.4
Hixon, D.5
Furlong, L.A.6
-
37
-
-
79959934105
-
Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil
-
Vianna F.S., Lopez-Camelo J.S., Leite J.C., Sanseverino M.T., Dutra Mda G., Castilla E.E., et al. Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil. PLoS One 2011, 6:e21735.
-
(2011)
PLoS One
, vol.6
-
-
Vianna, F.S.1
Lopez-Camelo, J.S.2
Leite, J.C.3
Sanseverino, M.T.4
Dutra Mda, G.5
Castilla, E.E.6
-
38
-
-
24644492970
-
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species
-
Wells P.G., Bhuller Y., Chen C.S., Jeng W., Kasapinovic S., Kennedy J.C., et al. Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species. Toxicol Appl Pharmacol 2005, 207:354-366.
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, pp. 354-366
-
-
Wells, P.G.1
Bhuller, Y.2
Chen, C.S.3
Jeng, W.4
Kasapinovic, S.5
Kennedy, J.C.6
-
39
-
-
79957868414
-
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure
-
Zimmer B., Schildknecht S., Kuegler P.B., Tanavde V., Kadereit S., Leist M. Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure. Toxicol Sci 2011, 121:357-367.
-
(2011)
Toxicol Sci
, vol.121
, pp. 357-367
-
-
Zimmer, B.1
Schildknecht, S.2
Kuegler, P.B.3
Tanavde, V.4
Kadereit, S.5
Leist, M.6
|