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Volumn 34, Issue 5, 2012, Pages 505-512

Chlorpyrifos developmental neurotoxicity: Interaction with glucocorticoids in PC12 cells

Author keywords

Chlorpyrifos; Dexamethasone; Glucocorticoids; Organophosphate pesticides; PC12 cells; Preterm delivery

Indexed keywords

CHLORPYRIFOS; DEXAMETHASONE; GLUCOCORTICOID;

EID: 84864487311     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2012.07.002     Document Type: Article
Times cited : (22)

References (62)
  • 1
    • 0034820215 scopus 로고    scopus 로고
    • Action of glucocorticoids on survival of nerve cells: promoting neurodegeneration or neuroprotection?
    • Abraham I.M., Harkany T., Horvath K.M., Luiten P.G.M. Action of glucocorticoids on survival of nerve cells: promoting neurodegeneration or neuroprotection?. J Neuroendocrinol 2001, 13:749-760.
    • (2001) J Neuroendocrinol , vol.13 , pp. 749-760
    • Abraham, I.M.1    Harkany, T.2    Horvath, K.M.3    Luiten, P.G.M.4
  • 2
    • 0034687836 scopus 로고    scopus 로고
    • Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death
    • Ahlbom E., Gogvadze V., Chen M., Celsi G., Ceccatelli S. Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death. Proc Natl Acad Sci 2000, 97:14726-14730.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 14726-14730
    • Ahlbom, E.1    Gogvadze, V.2    Chen, M.3    Celsi, G.4    Ceccatelli, S.5
  • 3
    • 70349835809 scopus 로고    scopus 로고
    • Neonatal stress affects vulnerability of cholinergic neurons and cognition in the rat: involvement of the HPA axis
    • Aisa B., Gil-Bea F.J., Marcos B., Tordera R., Lasheras B., Del Rio J., et al. Neonatal stress affects vulnerability of cholinergic neurons and cognition in the rat: involvement of the HPA axis. Psychoneuroendocrinology 2009, 34:1495-1505.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 1495-1505
    • Aisa, B.1    Gil-Bea, F.J.2    Marcos, B.3    Tordera, R.4    Lasheras, B.5    Del Rio, J.6
  • 4
    • 13844275027 scopus 로고    scopus 로고
    • Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions
    • Aldridge J.E., Meyer A., Seidler F.J., Slotkin T.A. Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions. Toxicol Appl Pharmacol 2005, 203:134-144.
    • (2005) Toxicol Appl Pharmacol , vol.203 , pp. 134-144
    • Aldridge, J.E.1    Meyer, A.2    Seidler, F.J.3    Slotkin, T.A.4
  • 5
    • 0029610549 scopus 로고
    • In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides
    • Bagchi D., Bagchi M., Hassoun E.A., Stohs S.J. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 1995, 104:129-140.
    • (1995) Toxicology , vol.104 , pp. 129-140
    • Bagchi, D.1    Bagchi, M.2    Hassoun, E.A.3    Stohs, S.J.4
  • 6
    • 84859330815 scopus 로고    scopus 로고
    • A strategy for comparing the contributions of environmental chemicals and other risk factors to neurodevelopment of children
    • Bellinger D.C. A strategy for comparing the contributions of environmental chemicals and other risk factors to neurodevelopment of children. Environ Health Perspect 2012, 120:501-507.
    • (2012) Environ Health Perspect , vol.120 , pp. 501-507
    • Bellinger, D.C.1
  • 7
    • 4243148518 scopus 로고    scopus 로고
    • Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets
    • Casida J.E., Quistad G.B. Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets. Chem Res Toxicol 2004, 17:983-998.
    • (2004) Chem Res Toxicol , vol.17 , pp. 983-998
    • Casida, J.E.1    Quistad, G.B.2
  • 8
    • 33745081870 scopus 로고    scopus 로고
    • Antenatal steroid therapy: have we undervalued the risks?
    • Cavalieri R.L., Cohen W.R. Antenatal steroid therapy: have we undervalued the risks?. J Matern Fetal Neonatal Med 2006, 19:265-269.
    • (2006) J Matern Fetal Neonatal Med , vol.19 , pp. 265-269
    • Cavalieri, R.L.1    Cohen, W.R.2
  • 9
    • 0027755967 scopus 로고
    • Pharmacokinetics of dexamethasone following single-dose intravenous administration to extremely low birth weight infants
    • Charles B., Schild P., Steer P., Cartwright D., Donovan T. Pharmacokinetics of dexamethasone following single-dose intravenous administration to extremely low birth weight infants. Dev Pharmacol Ther 1993, 20:205-210.
    • (1993) Dev Pharmacol Ther , vol.20 , pp. 205-210
    • Charles, B.1    Schild, P.2    Steer, P.3    Cartwright, D.4    Donovan, T.5
  • 10
    • 0027223872 scopus 로고
    • A comparison of the protective effect of dexamethasone to other potential prophylactic agents in a neonatal rat model of cerebral hypoxia-ischemia
    • Chumas P.D., Del Bigio M.R., Drake J.M., Tuor U.I. A comparison of the protective effect of dexamethasone to other potential prophylactic agents in a neonatal rat model of cerebral hypoxia-ischemia. J Neurosurg 1993, 79:414-420.
    • (1993) J Neurosurg , vol.79 , pp. 414-420
    • Chumas, P.D.1    Del Bigio, M.R.2    Drake, J.M.3    Tuor, U.I.4
  • 11
    • 30344433298 scopus 로고    scopus 로고
    • A case for revisiting the safety of pesticides: a closer look at neurodevelopment
    • Colborn T. A case for revisiting the safety of pesticides: a closer look at neurodevelopment. Environ Health Perspect 2006, 114:10-17.
    • (2006) Environ Health Perspect , vol.114 , pp. 10-17
    • Colborn, T.1
  • 12
    • 0028884527 scopus 로고
    • Effects of maternal stress on methylmercury-induced developmental toxicity in mice
    • Colomina M.T., Albina M.L., Domingo J.L., Corbella J. Effects of maternal stress on methylmercury-induced developmental toxicity in mice. Physiol Behav 1995, 58:979-983.
    • (1995) Physiol Behav , vol.58 , pp. 979-983
    • Colomina, M.T.1    Albina, M.L.2    Domingo, J.L.3    Corbella, J.4
  • 13
    • 0031859987 scopus 로고    scopus 로고
    • Neurotoxicity testing: a discussion of in vitro alternatives
    • Costa L.G. Neurotoxicity testing: a discussion of in vitro alternatives. Environ Health Perspect 1998, 106(Suppl. 2):505-510.
    • (1998) Environ Health Perspect , vol.106 , Issue.SUPPL. 2 , pp. 505-510
    • Costa, L.G.1
  • 14
    • 0037285397 scopus 로고    scopus 로고
    • Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates
    • Costa L.G., Cole T.B., Furlong C.E. Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. J Toxicol Clin Toxicol 2003, 41:37-45.
    • (2003) J Toxicol Clin Toxicol , vol.41 , pp. 37-45
    • Costa, L.G.1    Cole, T.B.2    Furlong, C.E.3
  • 15
    • 0034733973 scopus 로고    scopus 로고
    • Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?
    • Crumpton T.L., Seidler F.J., Slotkin T.A. Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?. Dev Brain Res 2000, 121:189-195.
    • (2000) Dev Brain Res , vol.121 , pp. 189-195
    • Crumpton, T.L.1    Seidler, F.J.2    Slotkin, T.A.3
  • 16
    • 0033230460 scopus 로고    scopus 로고
    • Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?
    • Das K.P., Barone S. Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?. Toxicol Appl Pharmacol 1999, 160:217-230.
    • (1999) Toxicol Appl Pharmacol , vol.160 , pp. 217-230
    • Das, K.P.1    Barone, S.2
  • 17
    • 34548508434 scopus 로고    scopus 로고
    • Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease
    • Drake A.J., Tang J.I., Nyirenda M.J. Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease. Clin Sci 2007, 113:219-232.
    • (2007) Clin Sci , vol.113 , pp. 219-232
    • Drake, A.J.1    Tang, J.I.2    Nyirenda, M.J.3
  • 18
    • 0030974286 scopus 로고    scopus 로고
    • Adrenergic differentiation potential in PC12 cells: influence of sodium butyrate and dexamethasone
    • Ebert S.N., Lindley S.E., Bengoechea T.G., Bain D., Wong D.L. Adrenergic differentiation potential in PC12 cells: influence of sodium butyrate and dexamethasone. Mol Brain Res 1997, 47:24-30.
    • (1997) Mol Brain Res , vol.47 , pp. 24-30
    • Ebert, S.N.1    Lindley, S.E.2    Bengoechea, T.G.3    Bain, D.4    Wong, D.L.5
  • 19
    • 0024550673 scopus 로고
    • Regulation of the differentiation of PC12 pheochromocytoma cells
    • Fujita K., Lazarovici P., Guroff G. Regulation of the differentiation of PC12 pheochromocytoma cells. Environ Health Perspect 1989, 80:127-142.
    • (1989) Environ Health Perspect , vol.80 , pp. 127-142
    • Fujita, K.1    Lazarovici, P.2    Guroff, G.3
  • 21
    • 1942437974 scopus 로고    scopus 로고
    • Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates
    • Gupta R.C. Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates. Toxicol Mech Methods 2004, 14:103-143.
    • (2004) Toxicol Mech Methods , vol.14 , pp. 103-143
    • Gupta, R.C.1
  • 22
    • 0030198949 scopus 로고    scopus 로고
    • Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone
    • Hassan A.H.S., von Rosenstiel P., Patchev V.K., Holsboer F., Almeida O.F.X. Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone. Exp Neurol 1996, 140:43-52.
    • (1996) Exp Neurol , vol.140 , pp. 43-52
    • Hassan, A.H.S.1    von Rosenstiel, P.2    Patchev, V.K.3    Holsboer, F.4    Almeida, O.F.X.5
  • 23
    • 23744456959 scopus 로고    scopus 로고
    • Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures
    • Howard A.S., Bucelli R., Jett D.A., Bruun D., Yang D.R. Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures. Toxicol Appl Pharmacol 2005, 207:112-124.
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 112-124
    • Howard, A.S.1    Bucelli, R.2    Jett, D.A.3    Bruun, D.4    Yang, D.R.5
  • 24
    • 33646361039 scopus 로고    scopus 로고
    • Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells
    • Jameson R.R., Seidler F.J., Qiao D., Slotkin T.A. Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells. Environ Health Perspect 2006, 114:667-672.
    • (2006) Environ Health Perspect , vol.114 , pp. 667-672
    • Jameson, R.R.1    Seidler, F.J.2    Qiao, D.3    Slotkin, T.A.4
  • 25
    • 33746288626 scopus 로고    scopus 로고
    • Adverse neurodevelopmental effects of dexamethasone modeled in PC12 cells: identifying the critical stages and concentration thresholds for the targeting of cell acquisition, differentiation and viability
    • Jameson R.R., Seidler F.J., Qiao D., Slotkin T.A. Adverse neurodevelopmental effects of dexamethasone modeled in PC12 cells: identifying the critical stages and concentration thresholds for the targeting of cell acquisition, differentiation and viability. Neuropsychopharmacology 2006, 31:1647-1658.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1647-1658
    • Jameson, R.R.1    Seidler, F.J.2    Qiao, D.3    Slotkin, T.A.4
  • 26
    • 0032079018 scopus 로고    scopus 로고
    • Cell death and associated c-jun induction in perinatal hypoxia-ischemia: effect of the neuroprotective drug dexamethasone
    • Macaya A., Munell F., Ferrer I., DeTorres C., Reventos J. Cell death and associated c-jun induction in perinatal hypoxia-ischemia: effect of the neuroprotective drug dexamethasone. Mol Brain Res 1998, 56:29-37.
    • (1998) Mol Brain Res , vol.56 , pp. 29-37
    • Macaya, A.1    Munell, F.2    Ferrer, I.3    DeTorres, C.4    Reventos, J.5
  • 27
    • 0036941158 scopus 로고    scopus 로고
    • Glucocorticoids, hypothalamo-pituitary-adrenal (HPA) development, and life after birth
    • Matthews S.G., Owen D., Banjanin S., Andrews M.H. Glucocorticoids, hypothalamo-pituitary-adrenal (HPA) development, and life after birth. Endocr Res 2002, 28:709-718.
    • (2002) Endocr Res , vol.28 , pp. 709-718
    • Matthews, S.G.1    Owen, D.2    Banjanin, S.3    Andrews, M.H.4
  • 28
    • 0022374001 scopus 로고
    • Biochemical effects of corticosteroids on neural tissues
    • Meyer J.S. Biochemical effects of corticosteroids on neural tissues. Physiol Rev 1985, 65:946-1020.
    • (1985) Physiol Rev , vol.65 , pp. 946-1020
    • Meyer, J.S.1
  • 29
    • 13844262784 scopus 로고    scopus 로고
    • Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide, chlorpyrifos
    • Meyer A., Seidler F.J., Aldridge J.E., Slotkin T.A. Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide, chlorpyrifos. Toxicol Appl Pharmacol 2005, 203:154-166.
    • (2005) Toxicol Appl Pharmacol , vol.203 , pp. 154-166
    • Meyer, A.1    Seidler, F.J.2    Aldridge, J.E.3    Slotkin, T.A.4
  • 30
  • 31
    • 26944487265 scopus 로고    scopus 로고
    • Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures
    • Mulholland P.J., Stepanyan T.D., Self R.L., Hensley A.K., Harris B.R., Kowalski A., et al. Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures. Neuroscience 2005, 136:259-267.
    • (2005) Neuroscience , vol.136 , pp. 259-267
    • Mulholland, P.J.1    Stepanyan, T.D.2    Self, R.L.3    Hensley, A.K.4    Harris, B.R.5    Kowalski, A.6
  • 33
    • 0036746131 scopus 로고    scopus 로고
    • Prevalence of fetal exposure to environmental toxins as determined by meconium analysis
    • Ostrea E.M., Morales V., Ngoumgna E., Prescilla R., Tan E., Hernandez E., et al. Prevalence of fetal exposure to environmental toxins as determined by meconium analysis. Neurotoxicology 2002, 23:329-339.
    • (2002) Neurotoxicology , vol.23 , pp. 329-339
    • Ostrea, E.M.1    Morales, V.2    Ngoumgna, E.3    Prescilla, R.4    Tan, E.5    Hernandez, E.6
  • 34
    • 78649726020 scopus 로고    scopus 로고
    • Gene-environmental interactions and organophosphate toxicity
    • Povey A.C. Gene-environmental interactions and organophosphate toxicity. Toxicology 2010, 278:294-304.
    • (2010) Toxicology , vol.278 , pp. 294-304
    • Povey, A.C.1
  • 36
    • 79952280670 scopus 로고    scopus 로고
    • The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring: studies in rhesus macaque and common marmoset
    • Pryce C.R., Aubert Y., Maier C., Pearce P.C., Fuchs E. The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring: studies in rhesus macaque and common marmoset. Psychopharmacology 2011, 214:33-53.
    • (2011) Psychopharmacology , vol.214 , pp. 33-53
    • Pryce, C.R.1    Aubert, Y.2    Maier, C.3    Pearce, P.C.4    Fuchs, E.5
  • 37
    • 33644699533 scopus 로고    scopus 로고
    • Examination of concurrent exposure to repeated stress and chlorpyrifos on cholinergic, glutamatergic, and monoamine neurotransmitter systems in rat forebrain regions
    • Pung T., Klein B., Blodgett D., Jortner B., Ehrich M. Examination of concurrent exposure to repeated stress and chlorpyrifos on cholinergic, glutamatergic, and monoamine neurotransmitter systems in rat forebrain regions. Int J Toxicol 2006, 25:65-80.
    • (2006) Int J Toxicol , vol.25 , pp. 65-80
    • Pung, T.1    Klein, B.2    Blodgett, D.3    Jortner, B.4    Ehrich, M.5
  • 38
    • 0034775369 scopus 로고    scopus 로고
    • Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells
    • Qiao D., Seidler F.J., Slotkin T.A. Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. Environ Health Perspect 2001, 109:909-913.
    • (2001) Environ Health Perspect , vol.109 , pp. 909-913
    • Qiao, D.1    Seidler, F.J.2    Slotkin, T.A.3
  • 39
    • 1642493774 scopus 로고    scopus 로고
    • Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos
    • Qiao D., Seidler F.J., Violin J.D., Slotkin T.A. Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos. Dev Brain Res 2003, 147:183-190.
    • (2003) Dev Brain Res , vol.147 , pp. 183-190
    • Qiao, D.1    Seidler, F.J.2    Violin, J.D.3    Slotkin, T.A.4
  • 40
    • 20444404601 scopus 로고    scopus 로고
    • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos
    • Qiao D., Seidler F.J., Slotkin T.A. Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. Toxicol Appl Pharmacol 2005, 206:17-26.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 17-26
    • Qiao, D.1    Seidler, F.J.2    Slotkin, T.A.3
  • 41
    • 49249116936 scopus 로고    scopus 로고
    • Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening
    • Radio N.M., Breier J.M., Shafer T.J., Mundy W.R. Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening. Toxicol Sci 2008, 105:106-118.
    • (2008) Toxicol Sci , vol.105 , pp. 106-118
    • Radio, N.M.1    Breier, J.M.2    Shafer, T.J.3    Mundy, W.R.4
  • 42
    • 79961050803 scopus 로고    scopus 로고
    • 7-Year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide
    • Rauh V., Arunajadai S., Horton M., Perera F., Hoepner L., Barr D.B., et al. 7-Year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide. Environ Health Perspect 2011, 10.1289/ehp.1003160.
    • (2011) Environ Health Perspect
    • Rauh, V.1    Arunajadai, S.2    Horton, M.3    Perera, F.4    Hoepner, L.5    Barr, D.B.6
  • 43
  • 44
    • 1442299469 scopus 로고    scopus 로고
    • Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats
    • Rhodes M.C., Seidler F.J., Qiao D., Tate C.A., Cousins M.M., Slotkin T.A. Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. Toxicol Appl Pharmacol 2004, 195:203-217.
    • (2004) Toxicol Appl Pharmacol , vol.195 , pp. 203-217
    • Rhodes, M.C.1    Seidler, F.J.2    Qiao, D.3    Tate, C.A.4    Cousins, M.M.5    Slotkin, T.A.6
  • 45
    • 45849085353 scopus 로고    scopus 로고
    • Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development
    • Rokyta R., Yamamotova A., Slamberova R., Franek M., Vaculin S., Hruba L., et al. Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development. Physiol Res 2008, 57(Suppl. 3):S79-S88.
    • (2008) Physiol Res , vol.57 , Issue.SUPPL. 3
    • Rokyta, R.1    Yamamotova, A.2    Slamberova, R.3    Franek, M.4    Vaculin, S.5    Hruba, L.6
  • 46
    • 40549097766 scopus 로고    scopus 로고
    • Pesticides and child neurodevelopment
    • Rosas L.G., Eskenazi B. Pesticides and child neurodevelopment. Curr Opin Pediatr 2008, 20:191-197.
    • (2008) Curr Opin Pediatr , vol.20 , pp. 191-197
    • Rosas, L.G.1    Eskenazi, B.2
  • 47
    • 14844314463 scopus 로고    scopus 로고
    • Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats
    • Roy T.S., Sharma V., Seidler F.J., Slotkin T.A. Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats. Dev Brain Res 2005, 155:71-80.
    • (2005) Dev Brain Res , vol.155 , pp. 71-80
    • Roy, T.S.1    Sharma, V.2    Seidler, F.J.3    Slotkin, T.A.4
  • 48
    • 77249099731 scopus 로고    scopus 로고
    • Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture
    • Rush T., Liu X.Q., Hjelmhaug J., Lobner D. Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture. Neuroscience 2010, 166:899-906.
    • (2010) Neuroscience , vol.166 , pp. 899-906
    • Rush, T.1    Liu, X.Q.2    Hjelmhaug, J.3    Lobner, D.4
  • 49
    • 44749094910 scopus 로고    scopus 로고
    • Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: effects on microtubule proteins
    • Sachana M., Flaskos J., Sidiropoulou E., Yavari C.A., Hargreaves A.J. Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: effects on microtubule proteins. Toxicol in Vitro 2008, 22:1387-1391.
    • (2008) Toxicol in Vitro , vol.22 , pp. 1387-1391
    • Sachana, M.1    Flaskos, J.2    Sidiropoulou, E.3    Yavari, C.A.4    Hargreaves, A.J.5
  • 50
    • 0242636645 scopus 로고    scopus 로고
    • Effects of daily stress or repeated paraoxon exposures on subacute pyridostigmine toxicity in rats
    • Shaikh J., Karanth S., Chakraborty D., Pruett S., Pope C.N. Effects of daily stress or repeated paraoxon exposures on subacute pyridostigmine toxicity in rats. Arch Toxicol 2003, 77:576-583.
    • (2003) Arch Toxicol , vol.77 , pp. 576-583
    • Shaikh, J.1    Karanth, S.2    Chakraborty, D.3    Pruett, S.4    Pope, C.N.5
  • 51
    • 0032908419 scopus 로고    scopus 로고
    • Developmental cholinotoxicants: nicotine and chlorpyrifos
    • Slotkin T.A. Developmental cholinotoxicants: nicotine and chlorpyrifos. Environ Health Perspect 1999, 107(Suppl. 1):71-80.
    • (1999) Environ Health Perspect , vol.107 , Issue.SUPPL. 1 , pp. 71-80
    • Slotkin, T.A.1
  • 52
    • 0842342126 scopus 로고    scopus 로고
    • Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates
    • Slotkin T.A. Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. Toxicol Appl Pharmacol 2004, 198:132-151.
    • (2004) Toxicol Appl Pharmacol , vol.198 , pp. 132-151
    • Slotkin, T.A.1
  • 53
    • 80855125087 scopus 로고    scopus 로고
    • Developmental neurotoxicity of organophosphates: a case study of chlorpyrifos
    • Elsevier Academic Press, San Diego, R.C. Gupta (Ed.)
    • Slotkin T.A. Developmental neurotoxicity of organophosphates: a case study of chlorpyrifos. Toxicity of organophosphate and carbamate pesticides 2005, 293-314. Elsevier Academic Press, San Diego. R.C. Gupta (Ed.).
    • (2005) Toxicity of organophosphate and carbamate pesticides , pp. 293-314
    • Slotkin, T.A.1
  • 54
    • 34249935494 scopus 로고    scopus 로고
    • Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats
    • Slotkin T.A., Seidler F.J. Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats. Brain Res Bull 2007, 73:301-309.
    • (2007) Brain Res Bull , vol.73 , pp. 301-309
    • Slotkin, T.A.1    Seidler, F.J.2
  • 55
    • 84856456273 scopus 로고    scopus 로고
    • Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro
    • Slotkin T.A., Seidler F.J. Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro. Neurotoxicol Teratol 2012, 34:232-241.
    • (2012) Neurotoxicol Teratol , vol.34 , pp. 232-241
    • Slotkin, T.A.1    Seidler, F.J.2
  • 56
    • 33845982947 scopus 로고    scopus 로고
    • Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine and divalent nickel
    • Slotkin T.A., MacKillop E.A., Ryde I.T., Tate C.A., Seidler F.J. Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine and divalent nickel. Environ Health Perspect 2007, 115:93-101.
    • (2007) Environ Health Perspect , vol.115 , pp. 93-101
    • Slotkin, T.A.1    MacKillop, E.A.2    Ryde, I.T.3    Tate, C.A.4    Seidler, F.J.5
  • 57
    • 0031722618 scopus 로고    scopus 로고
    • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells
    • Song X., Violin J.D., Seidler F.J., Slotkin T.A. Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. Toxicol Appl Pharmacol 1998, 151:182-191.
    • (1998) Toxicol Appl Pharmacol , vol.151 , pp. 182-191
    • Song, X.1    Violin, J.D.2    Seidler, F.J.3    Slotkin, T.A.4
  • 58
    • 70349952318 scopus 로고    scopus 로고
    • Chlorpyrifos induces delayed cytotoxicity after withdrawal in primary hippocampal neurons through extracellular signal-regulated kinase inhibition
    • Tan D.H., Peng S.Q., Wu Y.L., Wang Y.M., Lu C.F., Ding W., et al. Chlorpyrifos induces delayed cytotoxicity after withdrawal in primary hippocampal neurons through extracellular signal-regulated kinase inhibition. Biol Pharm Bull 2009, 32:1649-1655.
    • (2009) Biol Pharm Bull , vol.32 , pp. 1649-1655
    • Tan, D.H.1    Peng, S.Q.2    Wu, Y.L.3    Wang, Y.M.4    Lu, C.F.5    Ding, W.6
  • 59
    • 73249150364 scopus 로고    scopus 로고
    • Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review
    • Tegethoff M., Pryce C.R., Meinlschmidt G. Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review. Endocr Rev 2009, 30:753-789.
    • (2009) Endocr Rev , vol.30 , pp. 753-789
    • Tegethoff, M.1    Pryce, C.R.2    Meinlschmidt, G.3
  • 60
    • 0001073039 scopus 로고
    • Cultured PC12 cells: a model for neuronal function and differentiation
    • Academic Press, San Diego, J.E. Celis (Ed.)
    • Teng K.K., Greene L.A. Cultured PC12 cells: a model for neuronal function and differentiation. Cell biology: a laboratory handbook 1994, 218-224. Academic Press, San Diego. J.E. Celis (Ed.).
    • (1994) Cell biology: a laboratory handbook , pp. 218-224
    • Teng, K.K.1    Greene, L.A.2
  • 62
    • 0013836151 scopus 로고
    • Quantitative changes in DNA, RNA and protein during prenatal and postnatal growth in the rat
    • Winick M., Noble A. Quantitative changes in DNA, RNA and protein during prenatal and postnatal growth in the rat. Dev Biol 1965, 12:451-466.
    • (1965) Dev Biol , vol.12 , pp. 451-466
    • Winick, M.1    Noble, A.2


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