Expression alterations of genes on both neuronal and glial development in rats after developmental exposure to 6-propyl-2-thiouracil

Toxicology Letters

Volumn 228, Issue 3, 2014, Pages 225-234

  Shiraki, Ayako ^a,c   Saito, Fumiyo ^b   Akane, Hirotoshi ^a   Takeyoshi, Masahiro ^b   Imatanaka, Nobuya ^b   Itahashi, Megu ^a,c   Yoshida, Toshinori ^a   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

^c GIFU UNIVERSITY   (Japan)

Author keywords

Developmental neurotoxicity; Glial development; Hypothyroidism; Microarray; Myelination; Neurogenesis

Indexed keywords

CALRETININ; CYCLOOXYGENASE 2; DOUBLECORTIN; DRINKING WATER; EPHRIN; EPHRIN RECEPTOR B1; EPHRIN RECEPTOR B2; EPHRIN RECEPTOR B3; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MYELIN BASIC PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PARVALBUMIN; PROPYLTHIOURACIL; PROTEOLIPID PROTEIN; REELIN; SYNDECAN 2; TRANSCRIPTION FACTOR PAX6; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL LINEAGE; CELL MIGRATION; CELLULAR DISTRIBUTION; CEREBELLUM; CEREBELLUM VERMIS; CONTROLLED STUDY; CORPUS CALLOSUM; DENTATE GYRUS; DEVELOPMENTAL NEUROTOXICITY; DOWN REGULATION; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE TARGETING; GESTATIONAL AGE; GLIA CELL; HIGH THROUGHPUT SCREENING; HIPPOCAMPUS; HYPOTHYROIDISM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIMBIC SYSTEM; MALE; MICROARRAY ANALYSIS; MYELINATION; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WHITE MATTER;

DEVELOPMENTAL NEUROTOXICITY; GLIAL DEVELOPMENT; HYPOTHYROIDISM; MICROARRAY; MYELINATION; NEUROGENESIS;

AGE FACTORS; ANIMALS; BRAIN; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOTHYROIDISM; MALE; NEUROGENESIS; NEUROGLIA; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; THYROID HORMONES;

EID: 84901806441     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.04.018     Document Type: Article

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