Xanthohumol improves diet-induced obesity and fatty liver by suppressing Sterol Regulatory Element-binding Protein (SREBP) activation

Journal of Biological Chemistry

Volumn 290, Issue 33, 2015, Pages 20565-20579

  Miyata, Shingo ^a   Inoue, Jun ^a   Shimizu, Makoto ^a   Sato, Ryuichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOCHEMISTRY; CELL MEMBRANES; CHEMICAL ACTIVATION; CHOLESTEROL; GENE EXPRESSION; GENES; NUTRITION; PLANTS (BOTANY); PROTEINS; TRANSCRIPTION;

DIET-INDUCED OBESITY; ENDOPLASMIC RETICULUM; HEPATIC STEATOSIS; METABOLIC SYNDROMES; PHARMACOLOGICAL AGENTS; PRENYLATED FLAVONOIDS; STEROL REGULATORY ELEMENT-BINDING PROTEINS; TARGET GENE EXPRESSION;

FATTY ACIDS;

NUTRACEUTICAL; STEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; UNCLASSIFIED DRUG; XANTHOHUMOL; FLAVONOID; PROPIOPHENONE DERIVATIVE; SREBF1 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DIET INDUCED OBESITY; DIET THERAPY; DRUG MECHANISM; ENDOPLASMIC RETICULUM; FATTY ACID SYNTHESIS; FATTY LIVER; GENE EXPRESSION; GOLGI COMPLEX; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INACTIVATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHO CELL LINE; CRICETULUS; DIET; HAMSTER; METABOLISM; OBESITY; TUMOR CELL LINE;

HUMULUS; MUS;

ANIMALS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; DIET; FATTY LIVER; FLAVONOIDS; HUMANS; MICE; MICE, INBRED C57BL; OBESITY; PROPIOPHENONES; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84939632900     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.656975     Document Type: Article

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