Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles

Cell

Volumn 114, Issue 4, 2003, Pages 497-509

  Miller, Elizabeth A ^a   Beilharz, Traude H ^a   Malkus, Per N ^a   Lee, Marcus C S ^a   Hamamoto, Susan ^a   Orci, Lelio ^b   Schekman, Randy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BET1P PROTEIN; MEMBRANE PROTEIN; PROTEIN; PROTEIN SUBUNIT; SEC24P PROTEIN; SNARE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; MOLECULAR MECHANICS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0041526467     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00609-3     Document Type: Article

References (39)

1. Antonny B., Madden D., Hamamoto S., Orci L., Schekman R. Dynamics of the COPII coat with GTP and stable analogues. Nat. Cell Biol. 3:2001;531-537.
2. Aridor M., Traub L. Cargo selection in vesicular transport. the making and breaking of a coat Traffic. 3:2002;537-546. Erratum: Traffic 3(10), 762.
3. Aridor M., Weissman J., Bannykh S., Nuoffer C., Balch W.E. Cargo selection by the COPII budding machinery during export from the ER. J. Cell Biol. 141:1998;61-70.
4. Aridor M., Fish K.N., Bannykh S., Weissman J., Roberts T.H., Lippincott-Schwartz J., Balch W.E. The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J. Cell Biol. 152:2001;213-229.
5. Barlowe C., Orci L., Yeung T., Hosobuchi M., Hamamoto S., Salama N., Rexach M.F., Ravazzola M., Amherdt M., Schekman R. Copii. A membrane coat formed by sec proteins that drive vesicle budding from the endoplasmic reticulum Cell. 77:1994;895-907.
6. Belden W.J., Barlowe C. Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complex. J. Biol. Chem. 276:2001;43040-43048. a.
7. Belden W.J., Barlowe C. Role of Erv29p in collecting soluble secretory proteins into ER-derived transport vesicles. Science. 294:2001;1528-1531. b.
8. Bi X., Corpina R.A., Goldberg J. Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat. Nature. 419:2002;271-277.
9. Kappeler F., Klopfenstein D.R., Foguet M., Paccaud J.P., Hauri H.P. The recycling of ERGIC-53 in the early secretory pathway. ERGIC-53 carries a cytosolic endoplasmic reticulum-exit determinant interacting with COPII. J. Biol. Chem. 272:1997;31801-31808.
10. Kuehn M.J., Schekman R., Ljungdahl P.O. Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. J. Cell Biol. 135:1996;585-595.
11. Kuehn M.J., Herrmann J.M., Schekman R. COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature. 391:1998;187-190.
12. Kurihara T., Hamamoto S., Gimeno R.E., Kaiser C.A., Schekman R., Yoshihisa T. Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae. Mol. Biol. Cell. 11:2000;983-998.
13. Malkus P., Jiang F., Schekman R. Concentrative sorting of secretory cargo proteins into COPII-coated vesicles. J. Cell Biol. 159:2002;915-921.
14. Miller E., Antonny B., Hamamoto S., Schekman R. Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J. 21:2002;6105-6113.
15. Misra S., Puertollano R., Kato Y., Bonifacino J.S., Hurley J.H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature. 415:2002;933-937.
16. Mossessova E., Bickford L.C., Goldberg J. SNARE selectivity of the COPII coat. Cell. 114:2003;483-495. this issue.
17. Mumberg D., Muller R., Funk M. Regulatable promoters of Saccharomyces cerevisiae. comparison of transcriptional activity and their use for heterologous expression Nucleic Acids Res. 22:1994;5767-5768.
18. Muniz M., Nuoffer C., Hauri H.P., Riezman H. The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles. J. Cell Biol. 148:2000;925-930.
19. Nakamura N., Yamazaki S., Sato K., Nakano A., Sakaguchi M., Mihara K. Identification of potential regulatory elements for the transport of Emp24p. Mol. Biol. Cell. 9:1998;3493-3503.
20. Nishimura N., Balch W.E. A di-acidic signal required for selective export from the endoplasmic reticulum. Science. 277:1997;556-558.
21. Nishimura N., Bannykh S., Slabough S., Matteson J., Altschuler Y., Hahn K., Balch W.E. A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum. J. Biol. Chem. 274:1999;15937-15946.
22. Nufer O., Guldbrandsen S., Degen M., Kappeler F., Paccaud J.P., Tani K., Hauri H.P. Role of cytoplasmic C-terminal amino acids of membrane proteins in ER export. J. Cell Sci. 115:2002;619-628.
23. Otte S., Barlowe C. The Erv41p-Erv46p complex. multiple export signals are required in trans for COPII-dependent transport from the ER EMBO J. 21:2002;6095-6104.
24. Owen D.J., Evans P.R. A structural explanation for the recognition of tyrosine-based endocytotic signals. Science. 282:1998;1327-1332.
25. Owen D.J., Setiadi H., Evans P.R., McEver R.P., Green S.A. A third specificity-determining site in mu 2 adaptin for sequences upstream of Yxx phi sorting motifs. Traffic. 2:2001;105-110.
26. Peng R., Grabowski R., De Antoni A., Gallwitz D. Specific interaction of the yeast cis-Golgi syntaxin Sed5p and the coat protein complex II component Sec24p of endoplasmic reticulum-derived transport vesicles. Proc. Natl. Acad. Sci. USA. 96:1999;3751-3756.
27. Roberg K.J., Crotwell M., Espenshade P., Gimeno R., Kaiser C.A. LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J. Cell Biol. 145:1999;659-672.
28. Sato K., Nakano A. Emp47p and its close homolog Emp46p have a tyrosine-containing endoplasmic reticulum exit signal and function in glycoprotein secretion in Saccharomyces cerevisiae. Mol. Biol. Cell. 13:2002;2518-2532.
29. Schekman R., Orci L. Coat proteins and vesicle budding. Science. 271:1996;1526-1533.
30. Sevier C.S., Weisz O.A., Davis M., Machamer C.E. Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs. Mol. Biol. Cell. 11:2000;13-22.
31. Shiba T., Takatsu H., Nogi T., Matsugaki N., Kawasaki M., Igarashi N., Suzuki M., Kato R., Earnest T., Nakayama K., Wakatsuki S. Structural basis for recognition of acidic-cluster dileucine sequence by GGA1. Nature. 415:2002;937-941.
32. Shimoni Y., Kurihara T., Ravazzola M., Amherdt M., Orci L., Schekman R. Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J. Cell Biol. 151:2000;973-984.
33. Sikorski R.S., Hieter P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:1989;19-27.
34. Springer S., Schekman R. Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. Science. 281:1998;698-700.
35. Stockklausner C., Ludwig J., Ruppersberg J.P., Klocker N. A sequence motif responsible for ER export and surface expression of Kir2.0 inward rectifier K(+) channels. FEBS Lett. 493:2001;129-133.
36. Trilla J.A., Duran A., Roncero C. Chs7p, a new protein involved in the control of protein export from the endoplasmic reticulum that is specifically engaged in the regulation of chitin synthesis in Saccharomyces cerevisiae. J. Cell Biol. 145:1999;1153-1163.
37. Votsmeier C., Gallwitz D. An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export. EMBO J. 20:2001;6742-6750.
38. Wickner W., Haas A. Yeast homotypic vacuole fusion. a window on organelle trafficking mechanisms Annu. Rev. Biochem. 69:2000;247-275.
39. Wuestehube L.J., Schekman R.W. Reconstitution of transport from endoplasmic reticulum to Golgi complex using endoplasmic reticulum-enriched membrane fraction from yeast. Methods Enzymol. 219:1992;124-136.