-
1
-
-
50949125411
-
The efficiency of cellular energy transduction and its implications for obesity
-
Harper, M. E., Green, K., and Brand, M. D. (2008) The efficiency of cellular energy transduction and its implications for obesity. Annu. Rev. Nutr. 28, 13-33
-
(2008)
Annu. Rev. Nutr.
, vol.28
, pp. 13-33
-
-
Harper, M.E.1
Green, K.2
Brand, M.D.3
-
2
-
-
33846559121
-
Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo
-
DOI 10.1073/pnas.0610131104
-
Amara, C. E., Shankland, E. G., Jubrias, S. A., Marcinek, D. J., Kushmerick, M. J., and Conley, K. E. (2007) Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo. Proc. Natl. Acad. Sci. U.S.A. 104, 1057-1062 (Pubitemid 46154735)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 1057-1062
-
-
Amara, C.E.1
Shankland, E.G.2
Jubrias, S.A.3
Marcinek, D.J.4
Kushmerick, M.J.5
Conley, K.E.6
-
3
-
-
84455161659
-
Further support to the uncoupling-to-survive theory. The genetic variation of human UCP genes is associated with longevity
-
Rose, G., Crocco, P., De Rango, F., Montesanto, A., and Passarino, G. (2011) Further support to the uncoupling-to-survive theory. The genetic variation of human UCP genes is associated with longevity. PLoS ONE 6, e29650
-
(2011)
PLoS ONE
, vol.6
-
-
Rose, G.1
Crocco, P.2
De Rango, F.3
Montesanto, A.4
Passarino, G.5
-
4
-
-
35748953472
-
Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration
-
DOI 10.1074/jbc.M706129200
-
Anderson, E. J., Yamazaki, H., and Neufer, P. D. (2007) Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration. J. Biol. Chem. 282, 31257-31266 (Pubitemid 350044867)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.43
, pp. 31257-31266
-
-
Anderson, E.J.1
Yamazaki, H.2
Neufer, P.D.3
-
5
-
-
34249941195
-
A fundamental system of cellular energy homeostasis regulated by PGC-1α
-
DOI 10.1073/pnas.0702683104
-
Rohas, L. M., St-Pierre, J., Uldry, M., Jäger, S., Handschin, C., and Spiegelman, B. M. (2007) A fundamental system of cellular energy homeostasis regulated by PGC-1α. Proc. Natl. Acad. Sci. U.S.A. 104, 7933-7938 (Pubitemid 47185854)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.19
, pp. 7933-7938
-
-
Rohas, L.M.1
St-Pierre, J.2
Uldry, M.3
Jager, S.4
Handschin, C.5
Spiegelman, B.M.6
-
6
-
-
84864932595
-
Ablation of PGC1 β prevents mTOR dependent endoplasmic reticulum stress response
-
Camacho, A., Rodriguez-Cuenca, S., Blount, M., Prieur, X., Barbarroja, N., Fuller, M., Hardingham, G. E., and Vidal-Puig, A. (2012) Ablation of PGC1 β prevents mTOR dependent endoplasmic reticulum stress response. Exp. Neurol. 237, 396-406
-
(2012)
Exp. Neurol.
, vol.237
, pp. 396-406
-
-
Camacho, A.1
Rodriguez-Cuenca, S.2
Blount, M.3
Prieur, X.4
Barbarroja, N.5
Fuller, M.6
Hardingham, G.E.7
Vidal-Puig, A.8
-
7
-
-
62349117804
-
Getting the dose-response wrong. Why hormesis became marginalized and the threshold model accepted
-
Calabrese, E. J. (2009) Getting the dose-response wrong. Why hormesis became marginalized and the threshold model accepted. Arch. Toxicol. 83, 227-247
-
(2009)
Arch. Toxicol.
, vol.83
, pp. 227-247
-
-
Calabrese, E.J.1
-
8
-
-
54949139208
-
Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)- sulfoximine. Involvement of Nrf2 activation
-
Lee, H. R., Cho, J. M., Shin, D. H., Yong, C. S., Choi, H. G., Wakabayashi, N., and Kwak, M. K. (2008) Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)-sulfoximine. Involvement of Nrf2 activation. Mol. Cell. Biochem. 318, 23-31
-
(2008)
Mol. Cell. Biochem.
, vol.318
, pp. 23-31
-
-
Lee, H.R.1
Cho, J.M.2
Shin, D.H.3
Yong, C.S.4
Choi, H.G.5
Wakabayashi, N.6
Kwak, M.K.7
-
9
-
-
0033680064
-
Adaptive responses to peroxynitrite. Increased glutathione levels and cystine uptake in vascular cells
-
Buckley, B. J., and Whorton, A. R. (2000) Adaptive responses to peroxynitrite. increased glutathione levels and cystine uptake in vascular cells. Am. J. Physiol. Cell Physiol. 279, C1168-C1176
-
(2000)
Am. J. Physiol. Cell Physiol.
, vol.279
-
-
Buckley, B.J.1
Whorton, A.R.2
-
10
-
-
36349020163
-
Sites of Alkylation of Human Keap1 by Natural Chemoprevention Agents
-
DOI 10.1016/j.jasms.2007.09.015, PII S1044030507008483
-
Luo, Y., Eggler, A. L., Liu, D., Liu, G., Mesecar, A. D., and van Breemen, R. B. (2007) Sites of alkylation of human Keap1 by natural chemoprevention agents. J. Am. Soc. Mass Spectrom. 18, 2226-2232 (Pubitemid 350161332)
-
(2007)
Journal of the American Society for Mass Spectrometry
, vol.18
, Issue.12
, pp. 2226-2232
-
-
Luo, Y.1
Eggler, A.L.2
Liu, D.3
Liu, G.4
Mesecar, A.D.5
Van Breemen, R.B.6
-
11
-
-
81855166609
-
Glutathione depletion prevents diet-induced obesity and enhances insulin sensitivity
-
Findeisen, H. M., Gizard, F., Zhao, Y., Qing, H., Jones, K. L., Cohn, D., Heywood, E. B., and Bruemmer, D. (2011) Glutathione depletion prevents diet-induced obesity and enhances insulin sensitivity. Obesity 19, 2429-2432
-
(2011)
Obesity
, vol.19
, pp. 2429-2432
-
-
Findeisen, H.M.1
Gizard, F.2
Zhao, Y.3
Qing, H.4
Jones, K.L.5
Cohn, D.6
Heywood, E.B.7
Bruemmer, D.8
-
12
-
-
84859475161
-
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
-
Zarse, K., Schmeisser, S., Groth, M., Priebe, S., Beuster, G., Kuhlow, D., Guthke, R., Platzer, M., Kahn, C. R., and Ristow, M. (2012) Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal. Cell Metab. 15, 451-465
-
(2012)
Cell Metab.
, vol.15
, pp. 451-465
-
-
Zarse, K.1
Schmeisser, S.2
Groth, M.3
Priebe, S.4
Beuster, G.5
Kuhlow, D.6
Guthke, R.7
Platzer, M.8
Kahn, C.R.9
Ristow, M.10
-
13
-
-
70349512259
-
Reactive oxygen species enhance insulin sensitivity
-
Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N., Wu, B., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S., and Tiganis, T. (2009) Reactive oxygen species enhance insulin sensitivity. Cell Metab. 10, 260-272
-
(2009)
Cell Metab.
, vol.10
, pp. 260-272
-
-
Loh, K.1
Deng, H.2
Fukushima, A.3
Cai, X.4
Boivin, B.5
Galic, S.6
Bruce, C.7
Shields, B.J.8
Skiba, B.9
Ooms, L.M.10
Stepto, N.11
Wu, B.12
Mitchell, C.A.13
Tonks, N.K.14
Watt, M.J.15
Febbraio, M.A.16
Crack, P.J.17
Andrikopoulos, S.18
Tiganis, T.19
-
14
-
-
77956987110
-
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducingH2O2 and superoxide dismutase activity
-
Mesquita, A., Weinberger, M., Silva, A., Sampaio-Marques, B., Almeida, B., Leão, C., Costa, V., Rodrigues, F., Burhans, W. C., Ludovico, P. (2010) Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducingH2O2 and superoxide dismutase activity. Proc. Natl. Acad. Sci. U.S.A. 107, 15123-15128
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15123-15128
-
-
Mesquita, A.1
Weinberger, M.2
Silva, A.3
Sampaio-Marques, B.4
Almeida, B.5
Leão, C.6
Costa, V.7
Rodrigues, F.8
Burhans, W.C.9
Ludovico, P.10
-
15
-
-
23844553151
-
Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase
-
DOI 10.1021/tx050058x
-
Dietz, B. M., Kang, Y. H., Liu, G., Eggler, A. L., Yao, P., Chadwick, L. R., Pauli, G. F., Farnsworth, N. R., Mesecar, A. D., van Breemen, R. B., and Bolton, J. L. (2005) Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. Chem. Res. Toxicol. 18, 1296-1305 (Pubitemid 41170254)
-
(2005)
Chemical Research in Toxicology
, vol.18
, Issue.8
, pp. 1296-1305
-
-
Dietz, B.M.1
Kang, Y.-H.2
Liu, G.3
Eggler, A.L.4
Yao, P.5
Chadwick, L.R.6
Pauli, G.F.7
Farnsworth, N.R.8
Mesecar, A.D.9
Van Breemen, R.B.10
Bolton, J.L.11
-
16
-
-
84855214883
-
Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways
-
Festa, M., Capasso, A., D'Acunto, C. W., Masullo, M., Rossi, A. G., Pizza, C., and Piacente, S. (2011) Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways. J. Nat. Prod. 74, 2505-2513
-
(2011)
J. Nat. Prod.
, vol.74
, pp. 2505-2513
-
-
Festa, M.1
Capasso, A.2
D'Acunto, C.W.3
Masullo, M.4
Rossi, A.G.5
Pizza, C.6
Piacente, S.7
-
17
-
-
77955839687
-
Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism
-
Strathmann, J., Klimo, K., Sauer, S. W., Okun, J. G., Prehn, J. H., Gerhäuser, C. (2010) Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. FASEB J. 24, 2938-2950
-
(2010)
FASEB J.
, vol.24
, pp. 2938-2950
-
-
Strathmann, J.1
Klimo, K.2
Sauer, S.W.3
Okun, J.G.4
Prehn, J.H.5
Gerhäuser, C.6
-
18
-
-
84878890534
-
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats
-
Legette, L. L., Moreno Luna, A. Y., Reed, R. L., Miranda, C. L., Bobe, G., Proteau, R. R., and Stevens, J. F. (2013) Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats. Phytochemistry 91, 236-241
-
(2013)
Phytochemistry
, vol.91
, pp. 236-241
-
-
Legette, L.L.1
Moreno Luna, A.Y.2
Reed, R.L.3
Miranda, C.L.4
Bobe, G.5
Proteau, R.R.6
Stevens, J.F.7
-
19
-
-
77956094483
-
Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity
-
Mihalik, S. J., Goodpaster, B. H., Kelley, D. E., Chace, D. H., Vockley, J., Toledo, F. G., and DeLany, J. P. (2010) Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity. Obesity 18, 1695-1700
-
(2010)
Obesity
, vol.18
, pp. 1695-1700
-
-
Mihalik, S.J.1
Goodpaster, B.H.2
Kelley, D.E.3
Chace, D.H.4
Vockley, J.5
Toledo, F.G.6
DeLany, J.P.7
-
20
-
-
0017782874
-
Studies on fatty acid omega-oxidation. Antiketogenic effect and gluconeogenicity of dicarboxylic acids
-
Wada, F., and Usami, M. (1977) Studies on fatty acid omega-oxidation. Antiketogenic effect and gluconeogenicity of dicarboxylic acids. Biochim. Biophys. Acta 487, 361-368
-
(1977)
Biochim. Biophys. Acta
, vol.487
, pp. 361-368
-
-
Wada, F.1
Usami, M.2
-
21
-
-
0031128260
-
Prenylflavonoids from Humulus lupulus
-
DOI 10.1016/S0031-9422(96)00744-3, PII S0031942296007443
-
Stevens, J. F., Ivancic, M., Hsu, V. L., and Deinzer, M. L. (1997) Prenylflavonoids from Humulus lupulus. Phytochemistry 44, 1575-1585 (Pubitemid 27142313)
-
(1997)
Phytochemistry
, vol.44
, Issue.8
, pp. 1575-1585
-
-
Stevens, J.F.1
Ivancic, M.2
Hsu, V.L.3
Deinzer, M.L.4
-
22
-
-
0033964084
-
Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells
-
DOI 10.1016/S0304-3835(99)00328-6, PII S0304383599003286
-
Miranda, C. L., Aponso, G. L., Stevens, J. F., Deinzer, M. L., and Buhler, D. R. (2000) Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells. Cancer Lett. 149, 21-29 (Pubitemid 30100556)
-
(2000)
Cancer Letters
, vol.149
, Issue.1-2
, pp. 21-29
-
-
Miranda, C.L.1
Aponso, G.L.M.2
Stevens, J.F.3
Deinzer, M.L.4
Buhler, D.R.5
-
23
-
-
0032765279
-
Fate of xanthohumol and related prenylflavonoids from hops to beer
-
DOI 10.1021/jf990101k
-
Stevens, J. F., Taylor, A. W., Clawson, J. E., and Deinzer, M. L. (1999) Fate of xanthohumol and related prenylflavonoids from hops to beer. J. Agric. Food Chem. 47, 2421-2428 (Pubitemid 29325134)
-
(1999)
Journal of Agricultural and Food Chemistry
, vol.47
, Issue.6
, pp. 2421-2428
-
-
Stevens, J.F.1
Taylor, A.W.2
Clawson, J.E.3
Deinzer, M.L.4
-
24
-
-
84856759577
-
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish
-
Kirkwood, J. S., Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M. G., and Stevens, J. F. (2012) Vitamin C deficiency activates the purine nucleotide cycle in zebrafish. J. Biol. Chem. 287, 3833-3841
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 3833-3841
-
-
Kirkwood, J.S.1
Lebold, K.M.2
Miranda, C.L.3
Wright, C.L.4
Miller, G.W.5
Tanguay, R.L.6
Barton, C.L.7
Traber, M.G.8
Stevens, J.F.9
-
25
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry, M., Yang, W., St-Pierre, J., Lin, J., Seale, P., and Spiegelman, B. M. (2006) Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 3, 333-341
-
(2006)
Cell Metab.
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
26
-
-
0003535936
-
-
3rd Ed., John Wiley & Sons, Inc., New York
-
Agresti, A. (2012) Categorical Data Analysis, 3rd Ed., pp. 274-282, John Wiley & Sons, Inc., New York
-
(2012)
Categorical Data Analysis
, pp. 274-282
-
-
Agresti, A.1
-
28
-
-
3543008400
-
Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols
-
DOI 10.1016/j.bbabio.2004.03.016, PII S0005272804001318
-
Brown, G. C., and Borutaite, V. (2004) Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite, and S-nitrosothiols. Biochim. Biophys. Acta 1658, 44-49 (Pubitemid 39013232)
-
(2004)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1658
, Issue.1-2
, pp. 44-49
-
-
Brown, G.C.1
Borutaite, V.2
-
29
-
-
29144515671
-
The basal proton conductance of mitochondria depends on adenine nucleotide translocase content
-
DOI 10.1042/BJ20050890
-
Brand, M. D., Pakay, J. L., Ocloo, A., Kokoszka, J., Wallace, D. C., Brookes, P. S., and Cornwall, E. J. (2005) The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. Biochem. J. 392, 353-362 (Pubitemid 41796524)
-
(2005)
Biochemical Journal
, vol.392
, Issue.2
, pp. 353-362
-
-
Brand, M.D.1
Pakay, J.L.2
Ocloo, A.3
Kokoszka, J.4
Wallace, D.C.5
Brookes, P.S.6
Cornwall, E.J.7
-
30
-
-
0037109064
-
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
-
DOI 10.1042/BJ20011672
-
McStay, G. P., Clarke, S. J., and Halestrap, A. P. (2002) Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. Biochem. J. 367, 541-548 (Pubitemid 35216831)
-
(2002)
Biochemical Journal
, vol.367
, Issue.2
, pp. 541-548
-
-
McStay, G.P.1
Clarke, S.J.2
Halestrap, A.P.3
-
31
-
-
79958735550
-
Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3
-
Mailloux, R. J., Seifert, E. L., Bouillaud, F., Aguer, C., Collins, S., and Harper, M. E. (2011) Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3. J. Biol. Chem. 286, 21865-21875
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 21865-21875
-
-
Mailloux, R.J.1
Seifert, E.L.2
Bouillaud, F.3
Aguer, C.4
Collins, S.5
Harper, M.E.6
-
32
-
-
0041465009
-
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
-
DOI 10.1093/emboj/cdg412
-
Echtay, K. S., Esteves, T. C., Pakay, J. L., Jekabsons, M. B., Lambert, A. J., Portero-Otín, M., Pamplona, R., Vidal-Puig, A. J., Wang, S., Roebuck, S. J., and Brand, M. D. (2003) A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. EMBO J. 22, 4103-4110 (Pubitemid 37021739)
-
(2003)
EMBO Journal
, vol.22
, Issue.16
, pp. 4103-4110
-
-
Echtay, K.S.1
Esteves, T.C.2
Pakay, J.L.3
Jekabsons, M.B.4
Lambert, A.J.5
Portero-Otin, M.6
Pamplona, R.7
Vidal-Puig, A.J.8
Wang, S.9
Roebuck, S.J.10
Brand, M.D.11
-
33
-
-
37049042842
-
Reduction of dehydroasorbic acid by animal tissues
-
Hughes, R. E. (1964) Reduction of dehydroasorbic acid by animal tissues. Nature 203, 1068-1069
-
(1964)
Nature
, vol.203
, pp. 1068-1069
-
-
Hughes, R.E.1
-
34
-
-
46449090664
-
Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults
-
Ashfaq, S., Abramson, J. L., Jones, D. P., Rhodes, S. D., Weintraub, W. S., Hooper, W. C., Vaccarino, V., Alexander, R. W., Harrison, D. G., and Quyyumi, A. A. (2008) Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults. Hypertension 52, 80-85
-
(2008)
Hypertension
, vol.52
, pp. 80-85
-
-
Ashfaq, S.1
Abramson, J.L.2
Jones, D.P.3
Rhodes, S.D.4
Weintraub, W.S.5
Hooper, W.C.6
Vaccarino, V.7
Alexander, R.W.8
Harrison, D.G.9
Quyyumi, A.A.10
-
35
-
-
0038324477
-
Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione
-
DOI 10.1002/jbt.10069
-
Berkeley, L. I., Cohen, J. F., Crankshaw, D. L., Shirota, F. N., and Nagasawa, H. T. (2003) Hepatoprotection by L-cysteine-glutathione-mixed disulfide, a sulfhydryl-modified prodrug of glutathione. J. Biochem. Mol. Toxicol. 17, 95-97 (Pubitemid 36575812)
-
(2003)
Journal of Biochemical and Molecular Toxicology
, vol.17
, Issue.2
, pp. 95-97
-
-
Berkeley, L.I.1
Cohen, J.F.2
Crankshaw, D.L.3
Shirota, F.N.4
Nagasawa, H.T.5
-
36
-
-
78651227092
-
The biological significance of methionine sulfoxide stereochemistry
-
Lee, B. C., and Gladyshev, V. N. (2011) The biological significance of methionine sulfoxide stereochemistry. Free Radic. Biol. Med. 50, 221-227
-
(2011)
Free Radic. Biol. Med.
, vol.50
, pp. 221-227
-
-
Lee, B.C.1
Gladyshev, V.N.2
-
37
-
-
33745209659
-
Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption
-
Soga, T., Baran, R., Suematsu, M., Ueno, Y., Ikeda, S., Sakurakawa, T., Kakazu, Y., Ishikawa, T., Robert, M., Nishioka, T., and Tomita, M. (2006) Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption. J. Biol. Chem. 281, 16768-16776
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16768-16776
-
-
Soga, T.1
Baran, R.2
Suematsu, M.3
Ueno, Y.4
Ikeda, S.5
Sakurakawa, T.6
Kakazu, Y.7
Ishikawa, T.8
Robert, M.9
Nishioka, T.10
Tomita, M.11
-
38
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves, T. R., Ussher, J. R., Noland, R. C., Slentz, D., Mosedale, M., Ilkayeva, O., Bain, J., Stevens, R., Dyck, J. R., Newgard, C. B., Lopaschuk, G. D., and Muoio, D. M. (2008) Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab. 7, 45-56
-
(2008)
Cell Metab.
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
Bain, J.7
Stevens, R.8
Dyck, J.R.9
Newgard, C.B.10
Lopaschuk, G.D.11
Muoio, D.M.12
-
39
-
-
0013964986
-
Hormone-fuel interrelationships during fasting
-
Cahill, G. F., Jr., Herrera, M. G., Morgan, A. P., Soeldner, J. S., Steinke, J., Levy, P. L., Reichard, G. A., Jr., and Kipnis, D. M. (1966) Hormone-fuel interrelationships during fasting. J. Clin. Invest. 45, 1751-1769
-
(1966)
J. Clin. Invest.
, vol.45
, pp. 1751-1769
-
-
Cahill Jr., G.F.1
Herrera, M.G.2
Morgan, A.P.3
Soeldner, J.S.4
Steinke, J.5
Levy, P.L.6
Reichard Jr., G.A.7
Kipnis, D.M.8
-
40
-
-
0014216476
-
Skeletal muscle lipids. 3. Analysis of the functioning of skeletal muscle lipids during fasting
-
Masoro, E. J. (1967) Skeletal muscle lipids. 3. Analysis of the functioning of skeletal muscle lipids during fasting. J. Biol. Chem. 242, 1111-1114
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 1111-1114
-
-
Masoro, E.J.1
-
41
-
-
77954905826
-
Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells. Effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression
-
Bell, J. A., Reed, M. A., Consitt, L. A., Martin, O. J., Haynie, K. R., Hulver, M. W., Muoio, D. M., and Dohm, G. L. (2010) Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells. Effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression. J. Clin. Endocrinol. Metab. 95, 3400-3410
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, pp. 3400-3410
-
-
Bell, J.A.1
Reed, M.A.2
Consitt, L.A.3
Martin, O.J.4
Haynie, K.R.5
Hulver, M.W.6
Muoio, D.M.7
Dohm, G.L.8
-
42
-
-
0029897973
-
Distinction of dicarboxylic aciduria due to medium-chain triglyceride feeding from that due to abnormal fatty acid oxidation and fasting in children
-
DOI 10.1016/S0026-0495(96)90047-5
-
Tserng, K. Y., Griffin, R. L., and Kerr, D. S. (1996) Distinction of dicarboxylic aciduria due to medium-chain triglyceride feeding from that due to abnormal fatty acid oxidation and fasting in children. Metabolism 45, 162-167 (Pubitemid 26102610)
-
(1996)
Metabolism: Clinical and Experimental
, vol.45
, Issue.2
, pp. 162-167
-
-
Tserng, K.-Y.1
Griffin, R.L.2
Kerr, D.S.3
-
43
-
-
0029012926
-
Dicarboxylic acids, an alternate fuel substrate in parenteral nutrition. An update
-
Grego, A. V., and Mingrone, G. (1995) Dicarboxylic acids, an alternate fuel substrate in parenteral nutrition. An update. Clin. Nutr. 14, 143-148
-
(1995)
Clin. Nutr.
, vol.14
, pp. 143-148
-
-
Grego, A.V.1
Mingrone, G.2
-
44
-
-
0026543758
-
Formation and degradation of dicarboxylic acids in relation to alterations in fatty acid oxidation in rats
-
Mortensen, P. B. (1992) Formation and degradation of dicarboxylic acids in relation to alterations in fatty acid oxidation in rats. Biochim. Biophys. Acta 1124, 71-79
-
(1992)
Biochim. Biophys. Acta
, vol.1124
, pp. 71-79
-
-
Mortensen, P.B.1
-
45
-
-
74349103322
-
Activation of oxidative stress response by hydroxyl substituted chalcones and cyclic chalcone analogues in mitochondria
-
Guzy, J., Vasková-Kubálková, J., Rozmer, Z., Fodor, K., Mareková, M., Poskrobová, M., and Perjési, P. (2010) Activation of oxidative stress response by hydroxyl substituted chalcones and cyclic chalcone analogues in mitochondria. FEBS Lett. 584, 567-570
-
(2010)
FEBS Lett.
, vol.584
, pp. 567-570
-
-
Guzy, J.1
Vasková-Kubálková, J.2
Rozmer, Z.3
Fodor, K.4
Mareková, M.5
Poskrobová, M.6
Perjési, P.7
-
46
-
-
84859175244
-
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration
-
Legette, L., Ma, L., Reed, R. L., Miranda, C. L., Christensen, J. M., Rodriguez-Proteau, R., and Stevens, J. F. (2012) Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration. Mol. Nutr. Food Res. 56, 466-474
-
(2012)
Mol. Nutr. Food Res.
, vol.56
, pp. 466-474
-
-
Legette, L.1
Ma, L.2
Reed, R.L.3
Miranda, C.L.4
Christensen, J.M.5
Rodriguez-Proteau, R.6
Stevens, J.F.7
-
47
-
-
78650068036
-
Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates
-
Garcia, J., Han, D., Sancheti, H., Yap, L. P., Kaplowitz, N., and Cadenas, E. (2010) Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates. J. Biol. Chem. 285, 39646-39654
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 39646-39654
-
-
Garcia, J.1
Han, D.2
Sancheti, H.3
Yap, L.P.4
Kaplowitz, N.5
Cadenas, E.6
-
48
-
-
77958501463
-
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase
-
Zmijewski, J. W., Banerjee, S., Bae, H., Friggeri, A., Lazarowski, E. R., and Abraham, E. (2010) Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase. J. Biol. Chem. 285, 33154-33164
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 33154-33164
-
-
Zmijewski, J.W.1
Banerjee, S.2
Bae, H.3
Friggeri, A.4
Lazarowski, E.R.5
Abraham, E.6
-
49
-
-
40149108041
-
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist
-
Mailloux, R. J., Bériault, R., Lemire, J., Singh, R., Chénier, D. R., Hamel, R. D., and Appanna, V. D. (2007) The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. PLoS ONE 2, e690
-
(2007)
PLoS ONE
, vol.2
-
-
Mailloux, R.J.1
Bériault, R.2
Lemire, J.3
Singh, R.4
Chénier, D.R.5
Hamel, R.D.6
Appanna, V.D.7
-
50
-
-
82755166890
-
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
-
Anastasiou, D., Poulogiannis, G., Asara, J. M., Boxer, M. B., Jiang, J. K., Shen, M., Bellinger, G., Sasaki, A. T., Locasale, J. W., Auld, D. S., Thomas, C. J., Vander Heiden, M. G., and Cantley, L. C. (2011) Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science 334, 1278-1283
-
(2011)
Science
, vol.334
, pp. 1278-1283
-
-
Anastasiou, D.1
Poulogiannis, G.2
Asara, J.M.3
Boxer, M.B.4
Jiang, J.K.5
Shen, M.6
Bellinger, G.7
Sasaki, A.T.8
Locasale, J.W.9
Auld, D.S.10
Thomas, C.J.11
Vander Heiden, M.G.12
Cantley, L.C.13
-
51
-
-
84858790233
-
Innovation. Metabolomics. The apogee of the omics trilogy
-
Patti, G. J., Yanes, O., and Siuzdak, G. (2012) Innovation. Metabolomics. The apogee of the omics trilogy. Nat. Rev. Mol. Cell Biol. 13, 263-269
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 263-269
-
-
Patti, G.J.1
Yanes, O.2
Siuzdak, G.3
-
52
-
-
58649100237
-
Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
-
Harvey, C. J., Thimmulappa, R. K., Singh, A., Blake, D. J., Ling, G., Wakabayashi, N., Fujii, J., Myers, A., and Biswal, S. (2009) Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress. Free Radic Biol. Med. 46, 443-453
-
(2009)
Free Radic Biol. Med.
, vol.46
, pp. 443-453
-
-
Harvey, C.J.1
Thimmulappa, R.K.2
Singh, A.3
Blake, D.J.4
Ling, G.5
Wakabayashi, N.6
Fujii, J.7
Myers, A.8
Biswal, S.9
-
53
-
-
0037294091
-
Quantitative and qualitative adaptation of skeletal muscle mitochondria to increased physical activity
-
DOI 10.1002/jcp.10224
-
Zoll, J., Koulmann, N., Bahi, L., Ventura-Clapier, R., and Bigard, A. X. (2003) Quantitative and qualitative adaptation of skeletal muscle mitochondria to increased physical activity. J. Cell Physiol. 194, 186-193 (Pubitemid 36043633)
-
(2003)
Journal of Cellular Physiology
, vol.194
, Issue.2
, pp. 186-193
-
-
Zoll, J.1
Koulmann, N.2
Bahi, L.3
Ventura-Clapier, R.4
Bigard, A.-X.5
-
54
-
-
0026585611
-
Intracellular compartmentation, structure, and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands. The "phosphocreatine circuit" for cellular energy homeostasis
-
Wallimann, T., Wyss, M., Brdiczka, D., Nicolay, K., and Eppenberger, H. M. (1992) Intracellular compartmentation, structure, and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands. The "phosphocreatine circuit" for cellular energy homeostasis. Biochem. J. 281, 21-40
-
(1992)
Biochem. J.
, vol.281
, pp. 21-40
-
-
Wallimann, T.1
Wyss, M.2
Brdiczka, D.3
Nicolay, K.4
Eppenberger, H.M.5
-
55
-
-
0036197545
-
Glutamine. An anaplerotic precursor
-
Bowtell, J. L., and Bruce, M. (2002) Glutamine. An anaplerotic precursor. Nutrition 18, 222-224
-
(2002)
Nutrition
, vol.18
, pp. 222-224
-
-
Bowtell, J.L.1
Bruce, M.2
-
56
-
-
0016220406
-
Intracellular free amino acid concentration in human muscle tissue
-
Bergström, J., Fürst, P., Norée, L. O., and Vinnars, E. (1974) Intracellular free amino acid concentration in human muscle tissue. J. Appl. Physiol. 36, 693-697
-
(1974)
J. Appl. Physiol.
, vol.36
, pp. 693-697
-
-
Bergström, J.1
Fürst, P.2
Norée, L.O.3
Vinnars, E.4
-
57
-
-
77955399279
-
Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation
-
Lehmann, R., Zhao, X., Weigert, C., Simon, P., Fehrenbach, E., Fritsche, J., Machann, J., Schick, F., Wang, J., Hoene, M., Schleicher, E. D., Häring, H. U., Xu, G., and Niess, A. M. (2010) Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation. PLoS ONE 5, e11519
-
(2010)
PLoS ONE
, vol.5
-
-
Lehmann, R.1
Zhao, X.2
Weigert, C.3
Simon, P.4
Fehrenbach, E.5
Fritsche, J.6
Machann, J.7
Schick, F.8
Wang, J.9
Hoene, M.10
Schleicher, E.D.11
Häring, H.U.12
Xu, G.13
Niess, A.M.14
-
58
-
-
79955947558
-
Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways
-
Li, L., Hossain, M. A., Sadat, S., Hager, L., Liu, L., Tam, L., Schroer, S., Huogen, L., Fantus, I. G., Connelly, P. W., Woo, M., and Ng, D. S. (2011) Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways. J. Biol. Chem. 286, 17809-17820
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17809-17820
-
-
Li, L.1
Hossain, M.A.2
Sadat, S.3
Hager, L.4
Liu, L.5
Tam, L.6
Schroer, S.7
Huogen, L.8
Fantus, I.G.9
Connelly, P.W.10
Woo, M.11
Ng, D.S.12
-
59
-
-
0035459640
-
Sex-dependent dietary obesity, induction of UCPs, and leptin expression in rat adipose tissues
-
Rodríguez, A. M., Quevedo-Coli, S., Roca, P., and Palou, A. (2001) Sex-dependent dietary obesity, induction of UCPs, and leptin expression in rat adipose tissues. Obes. Res. 9, 579-588
-
(2001)
Obes. Res.
, vol.9
, pp. 579-588
-
-
Rodríguez, A.M.1
Quevedo-Coli, S.2
Roca, P.3
Palou, A.4
-
60
-
-
0032998265
-
UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells
-
DOI 10.1016/S0014-5793(98)01713-X, PII S001457939801713X
-
Mao, W., Yu, X. X., Zhong, A., Li, W., Brush, J., Sherwood, S. W., Adams, S. H., and Pan, G. (1999) UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells. FEBS Lett. 443, 326-330 (Pubitemid 29080820)
-
(1999)
FEBS Letters
, vol.443
, Issue.3
, pp. 326-330
-
-
Mao, W.1
Yu, X.X.2
Zhong, A.3
Li, W.4
Brush, J.5
Sherwood, S.W.6
Adams, S.H.7
Pan, G.8
-
61
-
-
0035128672
-
UCP2 muscle gene transfer modifies mitochondrial membrane potential
-
DOI 10.1038/sj.ijo.0801484
-
Marti, A., Larrarte, E., Novo, F. J., Garcia, M., and Martinez, J. A. (2001) UCP2 muscle gene transfer modifies mitochondrial membrane potential. Int. J. Obes. Relat. Metab. Disord. 25, 68-74 (Pubitemid 32142386)
-
(2001)
International Journal of Obesity
, vol.25
, Issue.1
, pp. 68-74
-
-
Marti, A.1
Larrarte, E.2
Novo, F.J.3
Garcia, M.4
Martinez, J.A.5
-
62
-
-
47949110159
-
Electrochemical elucidation on the mechanism of uncoupling caused by hydrophobic weak acids
-
Ozaki, S., Kano, K., and Shirai, O. (2008) Electrochemical elucidation on the mechanism of uncoupling caused by hydrophobic weak acids. Phys. Chem. Chem. Phys. 10, 4449-4455
-
(2008)
Phys. Chem. Chem. Phys.
, vol.10
, pp. 4449-4455
-
-
Ozaki, S.1
Kano, K.2
Shirai, O.3
-
63
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
DOI 10.1038/nature04330, PII NATURE04330
-
Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., Schoonjans, K., Bianco, A. C., and Auwerx, J. (2006) Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439, 484-489 (Pubitemid 43152840)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Bianco, A.C.12
Auwerx, J.13
-
64
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
Thomas, C., Gioiello, A., Noriega, L., Strehle, A., Oury, J., Rizzo, G., Macchiarulo, A., Yamamoto, H., Mataki, C., Pruzanski, M., Pellicciari, R., Auwerx, J., and Schoonjans, K. (2009) TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 10, 167-177
-
(2009)
Cell Metab.
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
Macchiarulo, A.7
Yamamoto, H.8
Mataki, C.9
Pruzanski, M.10
Pellicciari, R.11
Auwerx, J.12
Schoonjans, K.13
-
65
-
-
25144446897
-
Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice
-
Nozawa, H. (2005) Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice. Biochem. Biophys. Res. Commun. 336, 754-761
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 754-761
-
-
Nozawa, H.1
-
66
-
-
84869232518
-
Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice
-
Hirata, H., Yimin, Segawa, S., Ozaki, M., Kobayashi, N., Shigyo, T., and Chiba, H. (2012) Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice. PLoS ONE 7, e49415
-
(2012)
PLoS ONE
, vol.7
-
-
Hirata, H.1
Yimin2
Segawa, S.3
Ozaki, M.4
Kobayashi, N.5
Shigyo, T.6
Chiba, H.7
-
67
-
-
81155153943
-
Bile acid metabolites in serum. Intraindividual variation and associations with coronary heart disease, metabolic syndrome, and diabetes mellitus
-
Steiner, C., Othman, A., Saely, C. H., Rein, P., Drexel, H., von Eckardstein, A., and Rentsch, K. M. (2011) Bile acid metabolites in serum. Intraindividual variation and associations with coronary heart disease, metabolic syndrome, and diabetes mellitus. PLoS ONE 6, e25006
-
(2011)
PLoS ONE
, vol.6
-
-
Steiner, C.1
Othman, A.2
Saely, C.H.3
Rein, P.4
Drexel, H.5
Von Eckardstein, A.6
Rentsch, K.M.7
|