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Volumn 586, Issue 13, 2012, Pages 1778-1782

4′-Hydroxyflavanone suppresses activation of sterol regulatory element-binding proteins and de novo lipid synthesis

Author keywords

Cholesterol; Fatty acid; Flavanone; SREBP

Indexed keywords

2' HYDROXYFLAVANONE; 3' HYDROXYFLAVANONE; 4' HYDROXYFLAVANONE; CHOLESTEROL; FATTY ACID; FATTY ACID SYNTHASE; FLAVANONE; FLAVANONE DERIVATIVE; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; 4'-HYDROXYFLAVANONE; FASN PROTEIN, HUMAN;

EID: 84862506071     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.04.060     Document Type: Article
Times cited : (13)

References (22)
  • 1
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • Cohen, J.C., Horton, J.D. and Hobbs, H.H. (2011) Human fatty liver disease: old questions and new insights. Science 332, 1519-1523.
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 4
    • 0034859111 scopus 로고    scopus 로고
    • Sterol-regulatory-element-binding protein 1c mediates insulin action on hepatic gene expression
    • DOI 10.1042/BST0290547
    • Ferre, P., Foretz, M., Azzout-Marniche, D., Becard, D. and Foufelle, F. (2001) Sterol-regulatory-element-binding protein 1c mediates insulin action on hepatic gene expression. Biochem. Soc. Trans. 29, 547-552. (Pubitemid 32783655)
    • (2001) Biochemical Society Transactions , vol.29 , Issue.4 , pp. 547-552
    • Ferre, P.1    Foretz, M.2    Azzout-Marniche, D.3    Becard, D.4    Foufelle, F.5
  • 6
    • 38649116056 scopus 로고    scopus 로고
    • Selective versus Total Insulin Resistance: A Pathogenic Paradox
    • DOI 10.1016/j.cmet.2007.12.009, PII S1550413107003828
    • Brown, M.S. and Goldstein, J.L. (2008) Selective versus total insulin resistance. a pathogenic paradox. Cell Metab. 7, 95-96. (Pubitemid 351168559)
    • (2008) Cell Metabolism , vol.7 , Issue.2 , pp. 95-96
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 34347406521 scopus 로고    scopus 로고
    • SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
    • DOI 10.1159/000100426
    • Ferre, P. and Foufelle, F. (2007) SREBP-1c transcription factor and lipid homeostasis: clinical perspective. Horm. Res. 68, 72-82. (Pubitemid 47026704)
    • (2007) Hormone Research , vol.68 , Issue.2 , pp. 72-82
    • Ferre, P.1    Foufelle, F.2
  • 8
    • 39849083646 scopus 로고    scopus 로고
    • SREBPs: The crossroads of physiological and pathological lipid homeostasis
    • DOI 10.1016/j.tem.2007.10.009, PII S1043276008000040
    • Raghow, R., Yellaturu, C., Deng, X., Park, E.A. and Elam, M.B. (2008) SREBPs: the crossroads of physiological and pathological lipid homeostasis. Trends Endocrinol. Metab. 19, 65-73. (Pubitemid 351317897)
    • (2008) Trends in Endocrinology and Metabolism , vol.19 , Issue.2 , pp. 65-73
    • Raghow, R.1    Yellaturu, C.2    Deng, X.3    Park, E.A.4    Elam, M.B.5
  • 9
    • 0028072097 scopus 로고
    • Blasticidin S deaminase gene from Aspergillus terreus (BSD): A new drug resistance gene for transfection of mammalian cells
    • DOI 10.1016/0167-4781(94)90224-0
    • Kimura, M., Takatsuki, A. and Yamaguchi, I. (1994) Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells. Biochim. Biophys. Acta 1219, 653-659. (Pubitemid 24353383)
    • (1994) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1219 , Issue.3 , pp. 653-659
    • Kimura, M.1    Takatsuki, A.2    Yamaguchi, I.3
  • 10
    • 0029958652 scopus 로고    scopus 로고
    • Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2
    • DOI 10.1074/jbc.271.43.26461
    • Sato, R., Inoue, J., Kawabe, Y., Kodama, T., Takano, T. and Maeda, M. (1996) Sterol-dependent transcriptional regulation of sterol regulatory elementbinding protein-2. J. Biol. Chem. 271, 26461-26464. (Pubitemid 26359040)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.43 , pp. 26461-26464
    • Sato, R.1    Inoue, J.2    Kawabe, Y.3    Kodama, T.4    Takano, T.5    Maeda, M.6
  • 11
    • 0033609775 scopus 로고    scopus 로고
    • Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription
    • Sato, R., Miyamoto, W., Inoue, J., Terada, T., Imanaka, T. and Maeda, M. (1999) Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription. J. Biol. Chem. 274, 24714-24720.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24714-24720
    • Sato, R.1    Miyamoto, W.2    Inoue, J.3    Terada, T.4    Imanaka, T.5    Maeda, M.6
  • 14
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • Goldstein, J.L., DeBose-Boyd, R.A. and Brown, M.S. (2006) Protein sensors for membrane sterols. Cell 124, 35-46.
    • (2006) Cell , vol.124 , pp. 35-46
    • Goldstein, J.L.1    DeBose-Boyd, R.A.2    Brown, M.S.3
  • 15
    • 78650861117 scopus 로고    scopus 로고
    • Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques
    • Tang, J.J., Li, J.G., Qi, W., Qiu, W.W., Li, P.S., Li, B.L. and Song, B.L. (2011) Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Cell Metab. 13, 44-56.
    • (2011) Cell Metab. , vol.13 , pp. 44-56
    • Tang, J.J.1    Li, J.G.2    Qi, W.3    Qiu, W.W.4    Li, P.S.5    Li, B.L.6    Song, B.L.7
  • 16
    • 77951218102 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit
    • Takeuchi, Y. et al. (2010) Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit. J. Biol. Chem. 285, 11681-11691.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11681-11691
    • Takeuchi, Y.1
  • 17
    • 69049116165 scopus 로고    scopus 로고
    • A small molecule that blocks fat synthesis by inhibiting the activation of SREBP
    • Kamisuki, S. et al. (2009) A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chem. Biol. 16, 882-892.
    • (2009) Chem. Biol. , vol.16 , pp. 882-892
    • Kamisuki, S.1
  • 18
    • 79953755370 scopus 로고    scopus 로고
    • AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulinresistant mice
    • Li, Y. et al. (2011) AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulinresistant mice. Cell Metab. 13, 376-388.
    • (2011) Cell Metab. , vol.13 , pp. 376-388
    • Li, Y.1
  • 19
    • 33746003938 scopus 로고    scopus 로고
    • Effect of different flavonoids on collagen synthesis in human fibroblasts
    • DOI 10.1007/s11130-006-0006-8
    • Stipcevic, T., Piljac, J. and Vanden Berghe, D. (2006) Effect of different flavonoids on collagen synthesis in human fibroblasts. Plant Foods Hum. Nutr. 61, 29-34. (Pubitemid 44065547)
    • (2006) Plant Foods for Human Nutrition , vol.61 , Issue.1 , pp. 29-34
    • Stipcevic, T.1    Piljac, J.2    Berghe, D.V.3
  • 22
    • 77953485038 scopus 로고    scopus 로고
    • Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells
    • Weedon-Fekjaer, M.S., Dalen, K.T., Solaas, K., Staff, A.C., Duttaroy, A.K. and Nebb, H.I. (2010) Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells. J. Lipid Res. 51, 1886-1896.
    • (2010) J. Lipid Res. , vol.51 , pp. 1886-1896
    • Weedon-Fekjaer, M.S.1    Dalen, K.T.2    Solaas, K.3    Staff, A.C.4    Duttaroy, A.K.5    Nebb, H.I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.