In Vitro Blood-Brain Barrier Models - An Overview of Established Models and New Microfluidic Approaches

Journal of Pharmaceutical Sciences

Volumn 104, Issue 9, 2015, Pages 2727-2746

  Wolff, Anette ^a   Antfolk, Maria ^a   Brodin, Birger ^b   Tenje, Maria ^a,c  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

BBB; BBB on a chip; blood brain barrier; cell culture; CNS; in vitro models; membranes

Indexed keywords

CLAUDIN; CLAUDIN 5; JUNCTIONAL ADHESION MOLECULE; OCCLUDIN; PROTEIN ZO1;

ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN CORTEX; BRAIN MICROCIRCULATION; COCULTURE; ELECTRIC RESISTANCE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; IN VITRO STUDY; MEMBRANE RESISTANCE; MICROFLUIDICS; MICROGLIA; NONHUMAN; PERICYTE; PHENOTYPE; PRIMARY CELL CULTURE; PROTEIN EXPRESSION; REVIEW; TIGHT JUNCTION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; METABOLISM; PHYSIOLOGY; PROCEDURES; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; CELL LINE; ENDOTHELIUM, VASCULAR; HUMANS; MICROFLUIDICS; MODELS, BIOLOGICAL;

EID: 84939268433     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24329     Document Type: Review

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