Murine in vitro model of the blood-brain barrier for evaluating drug transport

European Journal of Pharmaceutical Sciences

Volumn 42, Issue 1-2, 2011, Pages 148-155

  Shayan, Gilda ^a   Choi, Yong Seok ^b   Shusta, Eric V ^c   Shuler, Michael L ^a   Lee, Kelvin H ^b  

^a Cornell University   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

^c University of Wisconsin Madison   (United States)

Author keywords

Blood brain barrier; Co culture; Murine brain microvascular endothelial cell

Indexed keywords

CLAUDIN 5; FLUORESCEIN SODIUM; GLUCOSE TRANSPORTER 1; GLYCOPROTEIN P; OCCLUDIN; PROTEIN ZO1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; COCULTURE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG TRANSPORT; DRUG UPTAKE; ELECTRIC RESISTANCE; HYDROPHILICITY; HYDROPHOBICITY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REPRODUCIBILITY; SWINE; TIGHT JUNCTION; TRANSENDOTHELIAL ELECTRICAL RESISTANCE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM AGENTS; COCULTURE TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; PERMEABILITY; RATS; TIGHT JUNCTIONS;

EID: 78650678061     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.11.005     Document Type: Article

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