Blood-brain barrier dysfunction and recovery

Journal of Neural Transmission

Volumn 113, Issue 4, 2006, Pages 455-462

  De Boer, A G ^a   Gaillard, P J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cell culture; Gluocorticoids; In vitro blood brain barrier; Inflammatory disease; Interferon , ; Permeability

Indexed keywords

ACETYLCYSTEINE; ALPHA INTERFERON; BETA INTERFERON; GLUCOCORTICOID; INTERFERON BETA SERINE; SCAVENGER;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN DEPTH STIMULATION; CELL CULTURE; CELL MEMBRANE PERMEABILITY; ENCEPHALOMYELITIS; HUMAN; IN VITRO STUDY; INFLAMMATORY DISEASE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; GLUCOCORTICOIDS; HUMANS; INFLAMMATION; INTERFERON TYPE I; MODELS, NEUROLOGICAL; RATS; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION;

EID: 33645045874     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-005-0375-4     Document Type: Article

References (37)

1. KL Audus RT Borchardt 1986 Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism. Pharm Res 3 81 87
2. HG Augustin DH Kozian RC Johnson 1994 Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes. Bioessays 16 12 901 906
3. KL Black 1995 Biochemical opening of the blood-brain barrier. Adv Drug Deliv Rev 15 37 52
4. AM Blamire DC Anthony B Rajagopalan NR Sibson VH Perry P Styles 2000 Interleukin-1beta-induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study. J Neurosci 20 21 8153 8159
5. KM Boje 1995 Cerebrovascular permeability changes during experimental meningitis in the rat. J Pharmacol Exp Ther 274 1199 1203
6. AM Butt 1995 Effect of inflammatory agents on electrical resistance across the blood-brain barrier in pial microvessels of anaesthetized rats. Brain Res 696 145 150
7. de Boer AG, Sutanto W (eds) (1997) Drug transport across the blood-brain barrier: new experimental strategies. Harwood Scientific Publisher, Amsterdam
8. AG de Boer PJ Gaillard 2002 In vitro models of the blood-brain barrier: when to use which? Current Medicinal Chemistry - Central Nervous System Agents 2 3 203 209
9. AG de Boer ICJ van der Sandt PJ Gaillard 2003 The role of drug transporters at the BBB. Ann Rev Pharmacol Tox 43 629 656
10. HE de Vries EF Eppens M Prins J Kuiper ThJC Van Berkel AG De Boer DD Breimer 1995 Blood-brain barrier permeability during experimental allergic encephalomyelitis and acute septic shock. Pharm Res 12 12 1932 1936
11. M-P Dehouck S Méresse P Delorme J-C Fruchart R Cecchelli 1990 An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro. J Neurochem 54 1798 1801
12. PJ Gaillard AG De Boer 2000 Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug. Eur J Pharm Sci 12 95 102
13. PJ Gaillard AG De Boer DD Breimer 2003 Pharmacological investigations on lipopolysaccharide-induced permeability changes in the blood-brain barrier in vitro. Microvasc Res 65 1 24 31
14. PJ Gaillard LH Voorwinden JL Nielsen A Ivanov R Atsumi H Engman C Ringbom AG De Boer DD Breimer 2001 Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes. Eur J Pharm Sci 12 215 222
15. PJ Gaillard PH Van Der Meide AG De Boer DD Breimer 2001 Glucocorticoid and type I interferon interactions at the blood-brain barrier: relevance for drug therapies for multiple sclerosis. Neuroreport 12 10 2189 2193
16. MC Gillies T Su 1995 Interferon-alpha 2b enhances barrier function of bovine retinal microvascular endothelium in vitro. Microvasc Res 49 3 277 288
17. M Gumbleton KL Audus 2001 Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. J Pharm Sci 90 11 1681 1698
18. M Harzheim M Stepien-Mering R Schroder S Schmidt 2004 The expression of microfilament-associated cell-cell contacts in brain endothelial cells is modified by IFN-beta1a (Rebif). J Interferon Cytokine Res 24 12 711 716
19. D Hoheisel T Nitz H Franke J Wegener A Hakvoort T Tilling HJ Galla 1998 Hydrocortisone reinforces the blood-brain properties in a serum free cell culture system. Biochem Biophys Res Commun 247 2 312 315
20. IFNB Multiple Sclerosis Study Group 1993 Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43 655 661
21. IFNB Multiple Sclerosis Study Group and University of British Columbia MS/MRI Analysis Group 1995 Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. Neurology 45 1277 1285
22. RC Janzer MC Raff 1987 Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 325 253 257
23. J Kraus AK Ling S Hamm K Voigt P Oschmann B Engelhardt 2005 Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. Ann Neurol 56 2 192 205
24. Y Kustova A Grinberg AS Basile 1999 Increased blood-brain barrier permeability in lp-bm5 infected mice is mediated by neuroexcitatory mechanisms. Brain Res 839 1 153 163
25. P Lagrange IA Romero A Minn PA Revest 1999 Transendothelial permeability changes induced by free radicals in an in vitro model of the blood-brain barrier. Free Radic Biol Med 27 5-6 667 672
26. KM Mattila T Pirtilä K Blennow A Wallin M Vitanen H Frey 1994 Altered blood-brain barrier function in alzheimer's disease? Acta Neurol Scand 89 192 198
27. JE Merrill SP Murphy 1997 Inflammatory events at the blood brain barrier: regulation of adhesion molecules, cytokines, and chemokines by reactive nitrogen and oxygen species. Brain Behav Immun 11 4 245 263
28. N Müller 1995 Psychoneuroimmunology: implications for the drug treatment of psychiatric disorders. CNS Drugs 4 2 125 140
29. Pardridge WM (1991) Peptide drug delivery to the brain. Raven Press, New York
30. SD Poland GPA Rice GA Dekaban 1995 HIV-1 infection of human brain-derived microvascular endothelial cells in vitro. J Acquir Immune Defic Syndr Hum Retrovirol 8 437 445
31. M Ramsauer J Kunz D Krause R Dermietzel 1998 Regulation of a blood-brain barrier- specific enzyme expressed by cerebral pericytes (pericytic aminopeptidase) under cell culture conditions. J Cereb Blood Flow Metab 18 1270 1281
32. M Schluep J Bogousslavsky 1997 Emerging treatments in multiple sclerosis. Eur Neurol 38 216 221
33. N Tsao HP Hsu CM Wu CC Liu HY Lei 2001 Tumor necrosis factor-alpha causes an increase in blood-brain barrier permeability during sepsis. J Med Microbiol 50 9 812 821
34. A Tunkel WM Scheld 1993 Pathogenesis and pathophysiology of bacterial meningitis. Ann Rev Med 44 103 120
35. KC Williams WF Hickey 1994 Immunology of multiple sclerosis. Clin Neurosci 2 229 245
36. J Wilting B Brand-Saberi H Kurz B Christ 1995 Development of the embryonic vascular system. Cell Mol Biol Res 41 4 219 232
37. J Wilting B Christ 1989 An experimental and ultrastructural study on the development of the avian choroid plexus. Cell Tissue Res 255 487 494