메뉴 건너뛰기




Volumn 1479, Issue , 2012, Pages 17-30

An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood-brain barrier model

Author keywords

Astrocytes; Blood brain barrier; Porcine; Transendothelial electrical resistance

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; OCCLUDIN; PROTEIN ZO1; TRANSFERRIN;

EID: 84867064670     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.08.031     Document Type: Article
Times cited : (50)

References (67)
  • 1
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • N.J. Abbott, L. Ronnback, and E. Hansson Astrocyte-endothelial interactions at the blood-brain barrier Nat. Rev. Neurosci. 7 1 2006 41 53
    • (2006) Nat. Rev. Neurosci. , vol.7 , Issue.1 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 2
    • 0025311288 scopus 로고
    • Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells
    • P. Artursson Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells J. Pharm. Sci. 79 6 1990 476 482
    • (1990) J. Pharm. Sci. , vol.79 , Issue.6 , pp. 476-482
    • Artursson, P.1
  • 3
    • 33646798056 scopus 로고    scopus 로고
    • Comparison of drug efflux transport kinetics in various blood-brain barrier models
    • C.J. Bachmeier, W.J. Trickler, and D.W. Miller Comparison of drug efflux transport kinetics in various blood-brain barrier models Drug Metab. Dispos. 34 6 2006 998 1003
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.6 , pp. 998-1003
    • Bachmeier, C.J.1    Trickler, W.J.2    Miller, D.W.3
  • 4
    • 0033976389 scopus 로고    scopus 로고
    • Neural induction of the blood-brain barrier: Still an enigma
    • H.C. Bauer, and H. Bauer Neural induction of the blood-brain barrier: still an enigma Cell Mol. Neurobiol. 20 1 2000 13 28
    • (2000) Cell Mol. Neurobiol. , vol.20 , Issue.1 , pp. 13-28
    • Bauer, H.C.1    Bauer, H.2
  • 5
    • 3242682550 scopus 로고    scopus 로고
    • Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier
    • V. Berezowski, C. Landry, M. Dehouck, R. Cecchelli, and L. Fenart Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier Brain Res. 108 2004 1 9
    • (2004) Brain Res. , vol.108 , pp. 1-9
    • Berezowski, V.1    Landry, C.2    Dehouck, M.3    Cecchelli, R.4    Fenart, L.5
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0030297155 scopus 로고    scopus 로고
    • Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor
    • R.D. Broadwell, B.J. Baker-Cairns, P.M. Friden, C. Oliver, and J.C. Villegas Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor Exp. Neurol. 142 1 1996 47 65
    • (1996) Exp. Neurol. , vol.142 , Issue.1 , pp. 47-65
    • Broadwell, R.D.1    Baker-Cairns, B.J.2    Friden, P.M.3    Oliver, C.4    Villegas, J.C.5
  • 8
    • 0028879235 scopus 로고
    • Effect of inflammatory agents on electrical resistance across the blood-brain barrier in pial microvessels of anaesthetized rats
    • A.M. Butt Effect of inflammatory agents on electrical resistance across the blood-brain barrier in pial microvessels of anaesthetized rats Brain Res. Bull. 696 1995 145 150
    • (1995) Brain Res. Bull. , vol.696 , pp. 145-150
    • Butt, A.M.1
  • 9
    • 0025048342 scopus 로고
    • Electrical resistance across the blood-brain barrier in anaesthetized rats: A developmental study
    • A.M. Butt, H.C. Jones, and N.J. Abbott Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study J. Physiol. 429 1990 47 62
    • (1990) J. Physiol. , vol.429 , pp. 47-62
    • Butt, A.M.1    Jones, H.C.2    Abbott, N.J.3
  • 10
    • 33646088705 scopus 로고    scopus 로고
    • Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction
    • A.R. Calabria, C. Weidenfeller, A.R. Jones, H.E. de Vries, and E.V. Shusta Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction J. Neurochem. 97 4 2006 922 933
    • (2006) J. Neurochem. , vol.97 , Issue.4 , pp. 922-933
    • Calabria, A.R.1    Weidenfeller, C.2    Jones, A.R.3    De Vries, H.E.4    Shusta, E.V.5
  • 11
    • 0021324474 scopus 로고
    • Expression of gamma-glutamyltranspeptidase in a transformed rat cerebral endothelial cell line
    • M.L. Caspers, and C.A. Diglio Expression of gamma-glutamyltranspeptidase in a transformed rat cerebral endothelial cell line Biochim. Biophys. Acta 803 1-2 1984 1 6
    • (1984) Biochim. Biophys. Acta , vol.803 , Issue.12 , pp. 1-6
    • Caspers, M.L.1    Diglio, C.A.2
  • 13
    • 67651100897 scopus 로고    scopus 로고
    • Closing the gap between the in-vivo and in-vitro blood-brain barrier tightness
    • K.M. Cohen-Kashi, I. Cooper, and V.I. Teichberg Closing the gap between the in-vivo and in-vitro blood-brain barrier tightness Brain Res. 1284 2009 12 21
    • (2009) Brain Res. , vol.1284 , pp. 12-21
    • Cohen-Kashi, K.M.1    Cooper, I.2    Teichberg, V.I.3
  • 14
    • 0020081135 scopus 로고
    • Electrical resistance of brain microvascular endothelium
    • C. Crone, and S.P. Olesen Electrical resistance of brain microvascular endothelium Brain Res. 241 1 1982 49 55
    • (1982) Brain Res. , vol.241 , Issue.1 , pp. 49-55
    • Crone, C.1    Olesen, S.P.2
  • 15
    • 0037427379 scopus 로고    scopus 로고
    • Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier
    • T. Eisenblatter, S. Huwel, and H.J. Galla Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier Brain Res. 971 2 2003 221 231
    • (2003) Brain Res. , vol.971 , Issue.2 , pp. 221-231
    • Eisenblatter, T.1    Huwel, S.2    Galla, H.J.3
  • 16
    • 0029893476 scopus 로고    scopus 로고
    • Synergistic stimulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities by retinoic acid and astroglial factors in immortalized rat brain microvessel endothelial cells
    • B. El Hafny, J.-M. Bourre, and F. Roux Synergistic stimulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities by retinoic acid and astroglial factors in immortalized rat brain microvessel endothelial cells J. Cell. Physiol. 167 1996 451 460
    • (1996) J. Cell. Physiol. , vol.167 , pp. 451-460
    • El Hafny, B.1    Bourre, J.-M.2    Roux, F.3
  • 17
    • 45549102801 scopus 로고    scopus 로고
    • Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier
    • C. Forster, M. Burek, I.A. Romero, B. Weksler, P.O. Couraud, and D. Drenckhahn Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier J. Physiol. 586 7 2008 1937 1949
    • (2008) J. Physiol. , vol.586 , Issue.7 , pp. 1937-1949
    • Forster, C.1    Burek, M.2    Romero, I.A.3    Weksler, B.4    Couraud, P.O.5    Drenckhahn, D.6
  • 18
    • 0033528231 scopus 로고    scopus 로고
    • An improved low-permeability in vitro-model of the blood-brain barrier: Transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol
    • H. Franke, H.J. Galla, and C.T. Beuckmann An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol Brain Res. 818 1999 65 71
    • (1999) Brain Res. , vol.818 , pp. 65-71
    • Franke, H.1    Galla, H.J.2    Beuckmann, C.T.3
  • 19
    • 0033638592 scopus 로고    scopus 로고
    • Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier
    • P.J. Gaillard, I.C. van der Sandt, L.H. Voorwinden, D. Vu, J.L. Nielsen, A.G. de Boer, and D.D. Breimer Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier Pharm. Res. 17 10 2000 1198 1205
    • (2000) Pharm. Res. , vol.17 , Issue.10 , pp. 1198-1205
    • Gaillard, P.J.1    Van Der Sandt, I.C.2    Voorwinden, L.H.3    Vu, D.4    Nielsen, J.L.5    De Boer, A.G.6    Breimer, D.D.7
  • 20
    • 0033673170 scopus 로고    scopus 로고
    • Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes
    • P.J. Gaillard, L.H. Voorwinden, J.L. Nielsen, A. Ivanov, R. Atsumi, H. Engman, C. Ringbom, A.G. de Boer, and D.D. Breimer Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes Eur. J. Pharm. Sci. 12 3 2001 215 222
    • (2001) Eur. J. Pharm. Sci. , vol.12 , Issue.3 , pp. 215-222
    • Gaillard, P.J.1    Voorwinden, L.H.2    Nielsen, J.L.3    Ivanov, A.4    Atsumi, R.5    Engman, H.6    Ringbom, C.7    De Boer, A.G.8    Breimer, D.D.9
  • 21
    • 0029066993 scopus 로고
    • Neoplastic and pharmacological influence on the permeability of an in vitro blood-brain barrier
    • P.A. Grabb, and M.R. Gilbert Neoplastic and pharmacological influence on the permeability of an in vitro blood-brain barrier J. Neurosurg. 82 6 1995 1053 1058
    • (1995) J. Neurosurg. , vol.82 , Issue.6 , pp. 1053-1058
    • Grabb, P.A.1    Gilbert, M.R.2
  • 22
    • 0024095524 scopus 로고
    • The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
    • B. Gumbiner, B. Stevenson, and A. Grimaldi The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex J. Cell Biol. 107 4 1988 1575 1587
    • (1988) J. Cell Biol. , vol.107 , Issue.4 , pp. 1575-1587
    • Gumbiner, B.1    Stevenson, B.2    Grimaldi, A.3
  • 23
    • 0035156232 scopus 로고    scopus 로고
    • Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier
    • M. Gumbleton, and K.L. Audus Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier J. Pharm. Sci 90 11 2001 1681 1698
    • (2001) J. Pharm. Sci , vol.90 , Issue.11 , pp. 1681-1698
    • Gumbleton, M.1    Audus, K.L.2
  • 24
    • 2442714838 scopus 로고    scopus 로고
    • Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts
    • S. Hamm, B. Dehouck, J. Kraus, K. Wolburg-Buchholz, H. Wolburg, W. Risau, R. Cecchelli, B. Engelhardt, and M.P. Dehouck Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts Cell Tissue Res. 315 2 2004 157 166
    • (2004) Cell Tissue Res. , vol.315 , Issue.2 , pp. 157-166
    • Hamm, S.1    Dehouck, B.2    Kraus, J.3    Wolburg-Buchholz, K.4    Wolburg, H.5    Risau, W.6    Cecchelli, R.7    Engelhardt, B.8    Dehouck, M.P.9
  • 25
    • 17644363679 scopus 로고    scopus 로고
    • In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro
    • R.F. Haseloff, I.E. Blasig, H.C. Bauer, and H. Bauer In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro Cell Mol. Neurobiol. 25 1 2005 25 39
    • (2005) Cell Mol. Neurobiol. , vol.25 , Issue.1 , pp. 25-39
    • Haseloff, R.F.1    Blasig, I.E.2    Bauer, H.C.3    Bauer, H.4
  • 26
    • 0031036530 scopus 로고    scopus 로고
    • Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes
    • Y. Hayashi, M. Nomura, S. Yamagishi, S. Harada, J. Yamashita, and H. Yamamoto Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes Glia 19 1 1997 13 26
    • (1997) Glia , vol.19 , Issue.1 , pp. 13-26
    • Hayashi, Y.1    Nomura, M.2    Yamagishi, S.3    Harada, S.4    Yamashita, J.5    Yamamoto, H.6
  • 28
    • 40849145621 scopus 로고    scopus 로고
    • In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier
    • P. Hsiao, T. Bui, R.J. Ho, and J.D. Unadkat In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier Drug Metab. Dispos. 36 3 2008 481 484
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.3 , pp. 481-484
    • Hsiao, P.1    Bui, T.2    Ho, R.J.3    Unadkat, J.D.4
  • 29
    • 0027324933 scopus 로고
    • Astrocytes secrete a factor inducing the expression of HT7-protein and neurothelin in endothelial cells of chorioallantoic vessels
    • R.C. Janzer, J.A. Lobrinus, P. Darekar, and L. Juillerat Astrocytes secrete a factor inducing the expression of HT7-protein and neurothelin in endothelial cells of chorioallantoic vessels Adv. Exp. Med. Biol. 331 1993 217 221
    • (1993) Adv. Exp. Med. Biol. , vol.331 , pp. 217-221
    • Janzer, R.C.1    Lobrinus, J.A.2    Darekar, P.3    Juillerat, L.4
  • 30
    • 0023108382 scopus 로고
    • Astrocytes induce blood-brain barrier properties in endothelial cells
    • R.C. Janzer, and M.C. Raff Astrocytes induce blood-brain barrier properties in endothelial cells Nature 325 6101 1987 253 257
    • (1987) Nature , vol.325 , Issue.6101 , pp. 253-257
    • Janzer, R.C.1    Raff, M.C.2
  • 31
    • 0242569629 scopus 로고    scopus 로고
    • A porcine astrocyte/endothelial cell co-culture model of the blood-brain barrier
    • V.V. Jeliazkova-Mecheva, and D.J. Bobilya A porcine astrocyte/endothelial cell co-culture model of the blood-brain barrier Brain Res. Brain Res. Protoc. 12 2003 91 98
    • (2003) Brain Res. Brain Res. Protoc. , vol.12 , pp. 91-98
    • Jeliazkova-Mecheva, V.V.1    Bobilya, D.J.2
  • 32
    • 4344638916 scopus 로고    scopus 로고
    • Evaluation of blood-brain barrier transporters by co-culture of brain capillary endothelial cells with astrocytes
    • Y. Kido, I. Tamai, T. Nakanishi, T. Kagami, I. Hirosawa, Y. Sai, and A. Tsuji Evaluation of blood-brain barrier transporters by co-culture of brain capillary endothelial cells with astrocytes Drug Metab. Pharmacokinet. 17 1 2002 34 41
    • (2002) Drug Metab. Pharmacokinet. , vol.17 , Issue.1 , pp. 34-41
    • Kido, Y.1    Tamai, I.2    Nakanishi, T.3    Kagami, T.4    Hirosawa, I.5    Sai, Y.6    Tsuji, A.7
  • 33
    • 0033606049 scopus 로고    scopus 로고
    • Astrocytes induce several blood-brain barrier properties in non-neural endothelial cells
    • S. Kuchler-Bopp, J.P. Delaunoy, J.C. Artault, M. Zaepfel, and J.B. Dietrich Astrocytes induce several blood-brain barrier properties in non-neural endothelial cells Neuroreport 10 6 1999 1347 1353
    • (1999) Neuroreport , vol.10 , Issue.6 , pp. 1347-1353
    • Kuchler-Bopp, S.1    Delaunoy, J.P.2    Artault, J.C.3    Zaepfel, M.4    Dietrich, J.B.5
  • 34
    • 0023324090 scopus 로고
    • Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues
    • L. Laitinen Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues Histochem. J. 19 1987 225 234
    • (1987) Histochem. J. , vol.19 , pp. 225-234
    • Laitinen, L.1
  • 35
    • 0025143227 scopus 로고
    • Astrocytes induce neural microvascular endothelial cells to form capillary-like structures in vitro
    • J. Laterra, C. Guerin, and G.W. Goldstein Astrocytes induce neural microvascular endothelial cells to form capillary-like structures in vitro J. Cell Physiol. 144 2 1990 204 215
    • (1990) J. Cell Physiol. , vol.144 , Issue.2 , pp. 204-215
    • Laterra, J.1    Guerin, C.2    Goldstein, G.W.3
  • 36
    • 1042302113 scopus 로고    scopus 로고
    • Development of an in vitro blood-brain barrier model based on immortalized porcine brain microvascular endothelial cells
    • R. Lauer, R. Bauer, B. Linz, F. Pittner, G.A. Peschek, G. Ecker, P. Friedl, and C.R. Noe Development of an in vitro blood-brain barrier model based on immortalized porcine brain microvascular endothelial cells Farmaco 59 2 2004 133 137
    • (2004) Farmaco , vol.59 , Issue.2 , pp. 133-137
    • Lauer, R.1    Bauer, R.2    Linz, B.3    Pittner, F.4    Peschek, G.A.5    Ecker, G.6    Friedl, P.7    Noe, C.R.8
  • 37
    • 0036238011 scopus 로고    scopus 로고
    • Transferrin/transferrin receptor-mediated drug delivery
    • H. Li, and Z.M. Qian Transferrin/transferrin receptor-mediated drug delivery Med. Res. Rev. 22 3 2002 225 250
    • (2002) Med. Res. Rev. , vol.22 , Issue.3 , pp. 225-250
    • Li, H.1    Qian, Z.M.2
  • 38
    • 77953405595 scopus 로고    scopus 로고
    • Differentiation of the brain vasculature: The answer came blowing by the Wnt
    • S. Liebner, and K.H. Plate Differentiation of the brain vasculature: the answer came blowing by the Wnt J. Angiogenes Res. 2 2010 1
    • (2010) J. Angiogenes Res. , vol.2 , pp. 1
    • Liebner, S.1    Plate, K.H.2
  • 39
    • 67549112082 scopus 로고    scopus 로고
    • A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2)
    • A. Mahringer, J. Delzer, and G. Fricker A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2) Eur. J. Pharm. Biopharm. 72 2009 605 613
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 605-613
    • Mahringer, A.1    Delzer, J.2    Fricker, G.3
  • 40
    • 0033574558 scopus 로고    scopus 로고
    • Increased permeability of primary cultured brain microvessel endothelial cell monolayers following TNF-alpha exposure
    • K.S. Mark, and D.W. Miller Increased permeability of primary cultured brain microvessel endothelial cell monolayers following TNF-alpha exposure Life Sci. 64 21 1999 1941 1953
    • (1999) Life Sci. , vol.64 , Issue.21 , pp. 1941-1953
    • Mark, K.S.1    Miller, D.W.2
  • 41
    • 0037081556 scopus 로고    scopus 로고
    • A co-culture-based model of human blood-brain barrier: Application to active transport of indinavir and in vivo-in vitro correlation
    • I. Megard, A. Garrigues, S. Orlowski, S. Jorajuria, P. Clayette, E. Ezan, and A. Mabondzo A co-culture-based model of human blood-brain barrier: application to active transport of indinavir and in vivo-in vitro correlation Brain Res. 927 2 2002 153 167
    • (2002) Brain Res. , vol.927 , Issue.2 , pp. 153-167
    • Megard, I.1    Garrigues, A.2    Orlowski, S.3    Jorajuria, S.4    Clayette, P.5    Ezan, E.6    Mabondzo, A.7
  • 42
    • 0033961913 scopus 로고    scopus 로고
    • Transferrin and transferrin receptor function in brain barrier systems
    • T. Moos, and E.H. Morgan Transferrin and transferrin receptor function in brain barrier systems Cell Mol. Neurobiol. 20 1 2000 77 95
    • (2000) Cell Mol. Neurobiol. , vol.20 , Issue.1 , pp. 77-95
    • Moos, T.1    Morgan, E.H.2
  • 43
    • 0017413222 scopus 로고
    • Five alpha-d-galactopyranosyl-binding isolectins from Bandeiraea simplicifolia seeds
    • L.A. Murphy, and I.J. Goldstein Five alpha-d-galactopyranosyl-binding isolectins from Bandeiraea simplicifolia seeds J. Biol. Chem. 252 1977 4739 4742
    • (1977) J. Biol. Chem. , vol.252 , pp. 4739-4742
    • Murphy, L.A.1    Goldstein, I.J.2
  • 45
    • 0141463768 scopus 로고    scopus 로고
    • Serum-derived factors weaken the barrier properties of cultured porcine brain capillary endothelial cells in vitro
    • T. Nitz, T. Eisenblatter, K. Psathaki, and H.J. Galla Serum-derived factors weaken the barrier properties of cultured porcine brain capillary endothelial cells in vitro Brain Res. 981 1-2 2003 30 40
    • (2003) Brain Res. , vol.981 , Issue.12 , pp. 30-40
    • Nitz, T.1    Eisenblatter, T.2    Psathaki, K.3    Galla, H.J.4
  • 49
    • 2042451616 scopus 로고    scopus 로고
    • Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures
    • P.T. Ronaldson, M. Bendayan, D. Gingras, M. Piquette-Miller, and R. Bendayan Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures J. Neurochem. 89 2004 788 800
    • (2004) J. Neurochem. , vol.89 , pp. 788-800
    • Ronaldson, P.T.1    Bendayan, M.2    Gingras, D.3    Piquette-Miller, M.4    Bendayan, R.5
  • 51
    • 0024318566 scopus 로고
    • Purification of murine endothelial cell cultures by flow cytometry using fluorescein-labeled griffonia simplicifolia agglutinin
    • G. Sahagun, S.A. Moore, Z. Fabry, R.L. Schelper, and M.N. Hart Purification of murine endothelial cell cultures by flow cytometry using fluorescein-labeled griffonia simplicifolia agglutinin Am. J. Pathol. 134 1989 1227 1232
    • (1989) Am. J. Pathol. , vol.134 , pp. 1227-1232
    • Sahagun, G.1    Moore, S.A.2    Fabry, Z.3    Schelper, R.L.4    Hart, M.N.5
  • 52
    • 0037408045 scopus 로고    scopus 로고
    • Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: Possible implications for the design of synthetic adenosine derivatives
    • M.P. Schaddelee, H.L. Voorwinden, E.W. van Tilburg, T.J. Pateman, A.P. Ijzerman, M. Danhof, and A.G. de Boer Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives Eur. J. Pharm. Sci. 19 2003 13 22
    • (2003) Eur. J. Pharm. Sci. , vol.19 , pp. 13-22
    • Schaddelee, M.P.1    Voorwinden, H.L.2    Van Tilburg, E.W.3    Pateman, T.J.4    Ijzerman, A.P.5    Danhof, M.6    De Boer, A.G.7
  • 53
    • 0032931698 scopus 로고    scopus 로고
    • Astrocytes enhance radical defence in capillary endothelial cells constituting the blood-brain barrier
    • M.L. Schroeter, K. Mertsch, H. Giese, S. Muller, A. Sporbert, and B. Hickel Astrocytes enhance radical defence in capillary endothelial cells constituting the blood-brain barrier FEBS Lett. 449 1999 241 244
    • (1999) FEBS Lett. , vol.449 , pp. 241-244
    • Schroeter, M.L.1    Mertsch, K.2    Giese, H.3    Muller, S.4    Sporbert, A.5    Hickel, B.6
  • 54
    • 0023904862 scopus 로고
    • Induction of gap junctions and brain endothelium-like tight junctions in cultured bovine endothelial cells: Local control of cell specialization
    • R.R. Shivers, F.E. Arthur, and P.D. Bowman Induction of gap junctions and brain endothelium-like tight junctions in cultured bovine endothelial cells: local control of cell specialization J. Submicrosc. Cytol. Pathol. 20 1 1988 1 14
    • (1988) J. Submicrosc. Cytol. Pathol. , vol.20 , Issue.1 , pp. 1-14
    • Shivers, R.R.1    Arthur, F.E.2    Bowman, P.D.3
  • 55
  • 56
    • 34447558546 scopus 로고    scopus 로고
    • Primary porcine brain microvascular endothelial cells: Biochemical and functional characterisation as a model for drug transport and targeting
    • M. Smith, Y. Omidi, and M. Gumbleton Primary porcine brain microvascular endothelial cells: biochemical and functional characterisation as a model for drug transport and targeting J. Drug Target 15 4 2007 253 268
    • (2007) J. Drug Target , vol.15 , Issue.4 , pp. 253-268
    • Smith, M.1    Omidi, Y.2    Gumbleton, M.3
  • 58
    • 0023948101 scopus 로고
    • Development of membrane interactions between brain endothelial cells and astrocytes in vitro
    • J.H. Tao-Cheng, and M.W. Brightman Development of membrane interactions between brain endothelial cells and astrocytes in vitro Int. J. Dev. Neurosci. 6 1 1988 25 37
    • (1988) Int. J. Dev. Neurosci. , vol.6 , Issue.1 , pp. 25-37
    • Tao-Cheng, J.H.1    Brightman, M.W.2
  • 59
    • 0030579090 scopus 로고    scopus 로고
    • Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains
    • M. Teifel, and P. Friedl Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains Exp. Cell Res. 228 1996 50 57
    • (1996) Exp. Cell Res. , vol.228 , pp. 50-57
    • Teifel, M.1    Friedl, P.2
  • 60
    • 0025107709 scopus 로고
    • Astrocyte-mediated induction of alkaline phosphatase activity in human umbilical cord vein endothelium: An in vitro model
    • S. Tio, M. Deenen, and E. Marani Astrocyte-mediated induction of alkaline phosphatase activity in human umbilical cord vein endothelium: an in vitro model Eur. J. Morphol. 28 2-4 1990 289 300
    • (1990) Eur. J. Morphol. , vol.28 , Issue.24 , pp. 289-300
    • Tio, S.1    Deenen, M.2    Marani, E.3
  • 61
    • 0024516199 scopus 로고
    • Isolation, characterization, and long-term cultivation of porcine and murine cerebral capillary endothelial cells
    • U. Tontsch, and H.C. Bauer Isolation, characterization, and long-term cultivation of porcine and murine cerebral capillary endothelial cells Microvasc. Res. 37 1989 148 161
    • (1989) Microvasc. Res. , vol.37 , pp. 148-161
    • Tontsch, U.1    Bauer, H.C.2
  • 62
    • 70349203738 scopus 로고    scopus 로고
    • Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro
    • M. von Wedel-Parlow, P. Wolte, and H.J. Galla Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro J. Neurochem. 111 1 2009 111 118
    • (2009) J. Neurochem. , vol.111 , Issue.1 , pp. 111-118
    • Von Wedel-Parlow, M.1    Wolte, P.2    Galla, H.J.3
  • 63
    • 65049090941 scopus 로고    scopus 로고
    • Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human
    • M.S. Warren, N. Zerangue, K. Woodford, L.M. Roberts, E.H. Tate, B. Feng, C. Li, T.J. Feuerstein, J. Gibbs, and B. Smith Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human Pharmacol. Res. 59 6 2009 404 413
    • (2009) Pharmacol. Res. , vol.59 , Issue.6 , pp. 404-413
    • Warren, M.S.1    Zerangue, N.2    Woodford, K.3    Roberts, L.M.4    Tate, E.H.5    Feng, B.6    Li, C.7    Feuerstein, T.J.8    Gibbs, J.9    Smith, B.10
  • 64
    • 0028246186 scopus 로고
    • Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes
    • H. Wolburg, J. Neuhaus, U. Kniesel, B. Krauss, E.M. Schmid, M. Ocalan, C. Farrell, and W. Risau Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes J. Cell Sci. 107 5 1994 1347 1357
    • (1994) J. Cell Sci. , vol.107 , Issue.5 , pp. 1347-1357
    • Wolburg, H.1    Neuhaus, J.2    Kniesel, U.3    Krauss, B.4    Schmid, E.M.5    Ocalan, M.6    Farrell, C.7    Risau, W.8
  • 66
    • 33751100685 scopus 로고    scopus 로고
    • Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability
    • Y. Zhang, C.S. Li, Y. Ye, K. Johnson, J. Poe, S. Johnson, W. Bobrowski, R. Garrido, and C. Madhu Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability Drug Metab. Dispos. 34 11 2006 1935 1943
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.11 , pp. 1935-1943
    • Zhang, Y.1    Li, C.S.2    Ye, Y.3    Johnson, K.4    Poe, J.5    Johnson, S.6    Bobrowski, W.7    Garrido, R.8    Madhu, C.9
  • 67
    • 44449091666 scopus 로고    scopus 로고
    • Pericyte-endothelial cell interaction increases MMP-9 secretion at the blood-brain barrier in vitro
    • A. Zozulya, C. Weidenfeller, and H.J. Galla Pericyte-endothelial cell interaction increases MMP-9 secretion at the blood-brain barrier in vitro Brain Res. 1189 2008 1 11
    • (2008) Brain Res. , vol.1189 , pp. 1-11
    • Zozulya, A.1    Weidenfeller, C.2    Galla, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.