Immortalized human brain endothelial cells and flow-based vascular modeling: A marriage of convenience for rational neurovascular studies

Journal of Cerebral Blood Flow and Metabolism

Volumn 28, Issue 2, 2008, Pages 312-328

  Cucullo, Luca ^a   Couraud, Pierre Olivier ^b,c,d,e   Weksler, Babette ^c,f   Romero, Ignacio Andres ^g   Hossain, Mohammed ^a   Rapp, Edward ^h   Janigro, Damir ^a,i  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^b INSTITUT COCHIN   (France)

^c INSERM   (France)

^d CNRS   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g OPEN UNIVERSITY   (United Kingdom)

^h Flocel Inc   (United States)

ⁱ LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Drug delivery; Drug discovery; Drug resistance; Pharmacodynamic; Shear stress

Indexed keywords

DIAZEPAM; GELATINASE B; GLUCOSE; IBUPROFEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PHENYTOIN; SUCROSE;

AEROBIC METABOLISM; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CIRCULATION; CELL IMMORTALIZATION; CONTROLLED STUDY; DRUG PENETRATION; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE; MEMBRANE MODEL; MEMBRANE PERMEABILITY; OSMOSIS; PRIORITY JOURNAL; REPERFUSION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CAPILLARIES; CELLS, CULTURED; CEREBROVASCULAR CIRCULATION; CYTOKINES; CYTOLOGICAL TECHNIQUES; DIURETICS; ELECTROPHYSIOLOGY; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GLUCOSE; HUMANS; INFLAMMATION; LACTIC ACID; LEUKOCYTES; MANNITOL; MATRIX METALLOPROTEINASE 9; MODELS, BIOLOGICAL; NEURONS; OSMOLAR CONCENTRATION; PHARMACEUTICAL PREPARATIONS; RATS; REPERFUSION INJURY; SUCROSE;

EID: 38549096764     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600525     Document Type: Article

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