Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (Calu-3 and BEAS2-B), Bronchiolar-Alveolar Cells (NCI-H292 and NCI-H441), and Alveolar Type II-like Cells (A549) by Liquid Chromatography-Tandem Mass Spectrometry

Journal of Pharmaceutical Sciences

Volumn 104, Issue 9, 2015, Pages 3029-3038

  Sakamoto, Atsushi ^a,b   Matsumaru, Takehisa ^a   Yamamura, Norio ^a   Suzuki, Shinobu ^a   Uchida, Yasuo ^b   Tachikawa, Masanori ^b   Terasaki, Tetsuya ^b  

^a NIPPON BOEHRINGER INGELHEIM CO LTD   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

cell lines; drug transport; mass spectrometry; membrane transporter; multidrug resistance associated proteins; organic cation transporters (OCT); proteomics; pulmonary delivery absorption; pulmonary drug delivery

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARNITINE TRANSPORTER 1; ORGANIC CATION TRANSPORTER;

ARTICLE; CONTROLLED STUDY; DRUG TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMORTALIZED CELL LINE; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS EPITHELIUM CELL; PRIMARY CELL CULTURE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; BRONCHIOLE; CELL LINE; EPITHELIUM CELL; LUNG ALVEOLUS; LUNG TUMOR; METABOLISM; PHYSIOLOGY; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

BIOLOGICAL TRANSPORT; BRONCHIOLES; CELL LINE; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; EPITHELIAL CELLS; HUMANS; LUNG NEOPLASMS; ORGANIC CATION TRANSPORT PROTEINS; PULMONARY ALVEOLI; TANDEM MASS SPECTROMETRY;

EID: 84939256706     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24381     Document Type: Article

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