Regulated vesicle trafficking of membrane transporters in hepatic epithelia

Journal of Hepatology

Volumn 42, Issue 4, 2005, Pages 592-603

  Marinelli, Raúl A ^a   Tietz, Pamela S ^b   Larusso, Nicholas F ^b  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; AQUAPORIN 8; CHLORINE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; POTASSIUM;

ANION EXCHANGE; BILE SECRETION; CELL MEMBRANE; EPITHELIUM CELL; HUMAN; IMMUNOBLOTTING; LIVER CELL; LIVER DISEASE; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 14844336303     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.01.001     Document Type: Review

References (97)

1. L. Hicke Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels Trends Cell Biol 9 1999 107 112
2. M. Benharouga, M. Haardt, N. Kartner, and G.L. Lukacs COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments J Cell Biol 153 2001 957 970
3. L. Hicke, and R. Dunn Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins Annu Rev Cell Dev Biol 19 2003 141 172
4. N.J. Bryant, R. Govers, and D.E. James Regulated transport of the glucose transporter GLUT4 Nat Rev Mol Cell Biol 3 2002 267 277
5. S. Nielsen, J. Frokiaer, D. Marples, T.H. Kwon, P. Agre, and M.A. Knepper Aquaporins in the kidney: from molecules to medicine Physiol Rev 82 2002 205 244
6. C.T. Okamoto, and J.G. Forte Vesicular trafficking machinery, the actin cytoskeleton, and H+-K+-ATPase recycling in the gastric parietal cell J Physiol 532 2001 287 296
7. R.A. Marinelli, L. Pham, P. Agre, and N.F. LaRusso Secretin promotes osmotic water transport in rat cholangiocytes by increasing aquaporin-1 water channels in plasma membrane. Evidence for secretin-induced vesicular translocation of aquaporin-1 J Biol Chem 272 1997 12984 12988
8. F. Garcia, A. Kierbel, M.C. Larocca, S.A. Gradilone, P. Splinter, and N.F. LaRusso The water channel aquaporin-8 is mainly intracellular in rat hepatocytes and its plasma membrane insertion is stimulated by cyclic AMP J Biol Chem 276 2001 12147 12152
9. +-taurocholate cotransport by translocating transporter to plasma membranes Am J Physiol 273 1997 G842 G848
10. H. Kipp, N. Pichetshote, and I.M. Arias Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver J Biol Chem 276 2001 7218 7224
11. R.C. Huebert, P.L. Splinter, F. García, R.A. Marinelli, and N.F. LaRusso Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion J Biol Chem 277 2002 22710 22717
12. C.J. Soroka, M.K. Pate, and J.L. Boyer Canalicular export pumps traffic with polymeric immunoglobulin A receptor on the same microtubule-associated vesicle in rat liver J Biol Chem 274 1999 26416 26424
13. H. Roelofsen, C.J. Soroka, D. Keppler, and J.L. Boyer Cycliz AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets J Cell Sci 111 1998 1137 1145
14. R. Kubitz, D. D'Urso, D. Keppler, and D. Haussinger Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane Gastroenterology 113 1997 1438 1442
15. S.A. Gradilone, F. Garcia, R.C. Huebert, P.S. Tietz, M.C. Larocca, and A. Kierbel Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes Hepatology 37 2003 1435 1441
16. F. Dombrowski, R. Kubitz, A. Chittattu, M. Wettstein, N. Saha, and D. Haussinger Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide Biochem J 348 2000 183 188
17. U. Beuers, M. Bilzer, A. Chittattu, G.A. Kullak-Ublick, D. Keppler, and G. Paumgartner Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver Hepatology 33 2001 1206 1216
18. P. Tietz, R.A. Marinelli, X.-M. Chen, J. Kole, M.A. McNiven, and N.F. LaRusso Agonist-induced coordinated trafficking of functionally-related transport proteins for water and ions in cholangiocytes J Biol Chem 278 2003 20413 20419
19. J.L. Boyer, and C.J. Soroka Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets Gastroenterology 109 1995 1600 1611
20. J.A. Dranoff, M. McClure, A.D. Burgstahler, L.A. Denson, A.R. Crawford, and J.M. Crawford Short-term regulation of bile acid uptake by microfilament-dependent translocation of rat ntcp to the plasma membrane Hepatology 30 1999 223 229
21. +/Taurocholate cotransporting polypeptide in rat liver Gastroenterology 107 1994 1781 1787
22. +/taurocholate cotransport by cyclic AMP J Biol Chem 268 1993 17734 17741
23. C.R. Webster, and M.S. Anwer Role of the PI3K/PKB signaling pathway in cAMP-mediated translocation of rat liver Ntcp Am J Physiol 277 1999 G1165 G1172
24. +/taurocholate cotransport and Ntcp translocation J Biol Chem 277 2002 28578 28583
25. M. McConkey, H. Gillin, C.R. Webster, and M.S. Anwer Cross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytes J Biol Chem 279 2004 20882 20888
26. C.R. Webster, C.J. Blanch, J. Phillips, and M.S. Anwer Cell swelling-induced translocation of rat liver Na(+)/taurocholate cotransport polypeptide is mediated via the phosphoinositide 3-kinase signaling pathway J Biol Chem 275 2000 29754 29760
27. C.R. Webster, C. Blanch, and M.S. Anwer Role of PP2B in cAMP-induced dephosphorylation and translocation of NTCP Am J Physiol 283 2002 G44 G50
28. S. Sarkar, E. Bananis, S. Nath, M.S. Anwer, J.W. Murray, and A.W. Wolkoff Vesicles containing Ntcp are a part of the recycling endosome pool and are enriched in dynein and myosin IIa. (Abstract) Hepatology 40 2004 487A
29. M. Ananthanarayanan, N. Balasubramaniam, B. Scneider, S. Anwer, and F. Suchy Critical role of vicinal and loop cysteine residues of human Na-taurocholate co-transporting polypeptide in taurocholate transport (Abstract) Hepatology 34 2001 474A
30. A.Q. Sun, I. Swaby, S. Xu, and F.J. Suchy Cell-specific basolateral membrane sorting of the human liver Na(+)-dependent bile acid cotransporter Am J Physiol 280 2001 G1305 G1313
31. M. Muller, and P.L. Jansen Molecular aspects of hepatobiliary transport Am J Physiol 272 1997 G1285 G1303
32. T. Gerloff, B. Stieger, B. Hagenbuch, J. Madon, L. Landmann, and J. Roth The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver J Biol Chem 273 1998 10046 10050
33. H. Kipp, N. Pichetshote, and I.M. Arias Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver J Biol Chem 276 2001 7218 7224
34. A.K. Kurz, D. Graf, M. Schmitt, S. Vom Dahl, and D. Haussinger Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats Gastroenterology 121 2001 407 419
35. S. Misra, P. Ujhazy, Z. Gatmaitan, L. Varticovski, and I.M. Arias The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver J Biol Chem 273 1998 26638 26644
36. S. Misra, L. Varticovski, and I.M. Arias Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles Am J Physiol 285 2003 G316 G324
37. H. Kipp, and I.M. Arias Intracellular trafficking and regulation of canalicular ATP-binding cassette transporters Semin Liver Dis 20 2000 339 351
38. R. Kubitz, G. Sutfels, T. Kuhlkamp, R. Kolling, and D. Haussinger Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase Gastroenterology 126 2004 541 553
39. Y. Wakabayashi, J. Lippincott-Schwartz, and I.M. Arias Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes Mol Biol Cell 15 2004 3485 3496
40. D. Haussinger, M. Schmitt, O. Weiergraber, and R. Kubitz Short-term regulation of canalicular transport Semin Liver Dis 20 2000 307 321
41. M. Schmitt, R. Kubitz, S. Lizun, M. Wettstein, and D. Haussinger Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity Hepatology 33 2001 509 518
42. B. Noe, F. Schliess, M. Wettstein, S. Heinrich, and D. Haussinger Regulation of taurocholate excretion by a hypo-osmolarity-activated signal transduction pathway in rat liver Gastroenterology 110 1996 858 865
43. M.J. Harris, M. Kuwano, M. Webb, and P.G. Board Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT) J Biol Chem 276 2001 20876 20881
44. S.B. Fernandez, Z. Hollo, A. Kern, E. Bakos, P.A. Fischer, and P. Borst Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells J Biol Chem 277 2002 31048 31055
45. Z.C. Gatmaitan, A.T. Nies, and I.M. Arias Regulation and translocation of ATP-dependent apical membrane proteins in rat liver Am J Physiol 272 1997 G1041 G1049
46. Y. Sai, A.T. Nies, and I.M. Arias Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells J Cell Sci 112 1999 4535 4545
47. P.J. Meier, R. Knickelbein, R.H. Moseley, J.W. Dobbins, and J.L. Boyer Evidence for carrier-mediated chloride/bicarbonate exchange in canalicular rat liver plasma membrane vesicles J Clin Invest 75 1985 1256 1263
48. - exchanger in isolated rat hepatocytes: role in regulation of intracellular pH Am J Physiol 261 1991 G512 G522
49. - exchanger in rat hepatocytes Proc Natl Acad Sci USA 91 1994 792 796
50. D. Alvaro, P. Della Guardia, A. Bini, A. Gigliozzi, S. Furfaro, and T. La Rosa Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets J Clin Invest 96 1995 665 675
51. S. Erlinger, and B. Flow I.M. Arias J.L. Boyer N. Fausto W.V. Jacoby D.A. Schachter D.A. Shafritz The liver: biology and pathobiology 1994 Raven New York, NY 769 786
52. G. Kilic, R.B. Doctor, and J.G. Fitz Insulin stimulates membrane conductance in a liver cell line: evidence for insertion of ion channels through a phosphoinositide 3-kinase-dependent mechanism J Biol Chem 276 2001 26762 26768
53. G. Calamita, A. Mazzone, A. Bizzoca, A. Cavalier, G. Cassano, and D. Thomas Expression and immunolocalization of the aquaporin-8 water channel in rat gastrointestinal tract Eur J Cell Biol 80 2001 711 719
54. Gradilone SA, Carreras FI, Lehmann GL, Marinelli RA. Phosphatidylinositol-3-kinase is involved in the glucagon-induced translocation of aquaporin-8 to hepatocyte plasma membrane. Biol Cell 2005 (in press).
55. H. Tsukaguchi, S. Weremowicz, C.C. Morton, and M.A. Hediger Functional and molecular characterization of the human neutral solute channel aquaporin-9 Am J Physiol 277 1999 F685 F696
56. M. Elkjaer, Z. Vajda, L.N. Nejsum, T. Kwon, U.B. Jensen, and M. Amiry-Moghaddam Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain Biochem Biophys Res Commun 276 2000 1118 1128
57. J.M. Carbrey, D.A. Gorelick-Feldman, D. Kozono, J. Praetorius, S. Nielsen, and P. Agre Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver Proc Natl Acad Sci USA 100 2003 2945 2950
58. K.N. Lazaridis, L. Pham, P. Tietz, R.A. Marinelli, P.C. deGroen, and S. Levine Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter J Clin Invest 100 1997 2714 2721
59. +-dependent bile acid transporter in large but not small rat cholangiocytes Gastroenterology 113 1997 1734 1740
60. K.N. Lazaridis, P. Tietz, T. Wu, S. Kip, P.A. Dawson, and N.F. LaRusso Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties Proc Natl Acad Sci USA 97 2000 11092 11097
61. +-dependent bile acid transporter on the cholangiocyte apical membrane regulates ductal reabsorption of bile acids and ductal bile secretion in bile duct ligated rats (Abstract) Hepatology 26 1997 261A
62. X. Xia, M. Roundtree, A. Merikhi, X. Lu, S. Shentu, and G. Lesage Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes J Biol Chem 279 2004 44931 44937
63. J.A. Cohn, T.V. Strong, M.R. Picciotto, A.C. Nairn, F.S. Collins, and J.G. Fitz Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells Gastroenterology 105 1993 1857 1864
64. P.S. Tietz, R.T. Holman, L.J. Miller, and N.F. LaRusso Isolation and characterization of rat cholangiocyte vesicles enriched in apical or basolateral plasma membrane domains Biochemistry 34 1995 15436 15443
65. E. Martinez-Anso, J.E. Castillo, J. Diez, J.F. Medina, and J. Prieto Immunohistochemical detection of chloride/bicarbonate anion exchangers in human liver Hepatology 19 1994 1400 1406
66. S.K. Roberts, M. Yano, Y. Ueno, L. Pham, G. Alpini, and P. Agre Cholangiocytes express the aquaporin CHIP and transport water via a channel-mediated mechanism Proc Natl Acad Sci USA 91 1994 13009 13013
67. R.A. Marinelli, P.S. Tietz, L.D. Pham, L. Rueckert, P. Agre, and N.F. LaRusso Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes Am J Physiol 276 1999 G280 G286
68. E. Cova, A. Gong, R.A. Marinelli, and N.F. LaRusso Water movement across rat bile duct units is transcellular and channel-mediated Hepatology 34 2001 456 463
69. A.Y. Gong, A.I. Masyuk, P.L. Splinter, R.C. Huebert, P.S. Tietz, and N.F. LaRusso Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units Am J Physiol 283 2002 C338 C346
70. P.L. Splinter, A.I. Masyuk, and N.F. LaRusso Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs J Biol Chem 278 2003 6268 6274
71. A. Mennone, A.S. Verkman, and J.L. Boyer Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice Am J Physiol 283 2002 G739 G746
72. R.A. Marinelli, L. Pham, P. Tietz, and N.F. LaRusso Expression of aquaporin-4 water channels in rat cholangiocytes Hepatology 31 2000 1313 1317
73. P.L. Splinter, R.C. Huebert, R.A. Marinelli, L.D. Pham, and N.F. LaRusso Expression and subcellular localization of liver epithelial cell aquaporins (Abstract) Hepatology 32 2000 175A
74. G.A. Kullak-Ublick, B. Stieger, and P.J. Meier Enterohepatic bile salt transporters in normal physiology and liver disease Gastroenterology 126 2004 322 342
75. D. Rost, J. Kartenbeck, and D. Keppler Changes in the localization of the rat canalicular conjugate export pump Mrp2 in phalloidin-induced cholestasis Hepatology 29 1999 814 821
76. R. Kubitz, M. Wettstein, U. Warskulat, and D. Haussinger Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone Gastroenterology 116 1999 401 410
77. M. Schmitt, R. Kubitz, M. Wettstein, S. vom Dahl, and D. Haussinger Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene Biol Chem 381 2000 487 495
78. A.D. Mottino, J. Cao, L.M. Veggi, F. Crocenzi, M.G. Roma, and M. Vore Altered localization and activity of canalicular Mrp2 in estradiol-17beta-d- glucuronide-induced cholestasis Hepatology 35 2002 1409 1419
79. F. Crocenzi, A.D. Mottino, E.J. Sanchez Pozzi, J.M. Pellegrino, E.A. Rodriguez Garay, and P. Milkiewicz Impaired localization and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat Gut 52 2003 1170 1177
80. F. Crocenzi, A.D. Mottino, J. Cao, L.M. Veggi, E.J. Pozzi, and M. Vore Estradiol-17beta-d-glucuronide induces endocytic internalization of Bsep in rats Am J Physiol 285 2003 G449 G459
81. Mottino AD, Crocenzi FA, Sanchez Pozzi EJ, Veggi LM, Roma MG, Vore M. Role of microtubules in estradiol-17{beta}-d-glucuronide-induced alteration of canalicular Mrp2 localization and activity. Am J Physiol Gastrointest Liver Physiol 2005;288:G327-G336.
82. S. Kikuchi, M. Hata, K. Fukumoto, Y. Yamane, T. Matsui, and A. Tamura Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranas Nat Genet 31 2002 320 325
83. H. Kojima, A.T. Nies, J. Konig, W. Hagmann, H. Spring, and M. Uemura Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis J Hepatol 39 2003 693 702
84. O. Kocher, N. Comella, A. Gilchrist, R. Pal, K. Tognazzi, and L.F. Brown PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein Lab Invest 79 1999 1161 1170
85. D.F. Ortiz, J. Moseley, G. Calderon, A.L. Swift, S. Li, and I.M. Arias Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells J Biol Chem 279 2004 32761 32770
86. F.A. Crocenzi, M.S. Portesio, C.L. Basiglio, R. Coleman, and M.G. Roma Silibinin prevents estradiol-17beta-d-glucuronide-induced excretory failure and internalisation of Bsep in the isolated rat hepatocyte model: possible involvement of cyclic AMP. (Abstract) J Hepatol 38 2003 81A
87. J.M. Crawford The role of vesicles in bile formation M.P. Manns J.L. Boyer P.L.M. Jansen J. Reichen Proceedings of falk symposium. Cholestatic liver diseases 1997 Kluwer Academic Publishers Dordrecht 36 45
88. F.I. Carreras, S.A. Gradilone, A. Mazzone, F. García, B.Q. Huang, and J.E. Ochoa Rat hepatocyte aquaporin-8 water channels are down-regulated in extrahepatic cholestasis Hepatology 37 2003 1026 1033
89. V. Keitel, J. Kartenbeck, A.T. Nies, H. Spring, M. Brom, and D. Keppler Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome Hepatology 32 2000 1317 1328
90. L. Wang, C.J. Soroka, and J.L. Boyer The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II J Clin Invest 110 2002 965 972
91. J.R. Plass, O. Mol, J. Heegsma, M. Geuken, J. de Bruin, and G. Elling A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump J Hepatol 40 2004 24 30
92. K. Hashimoto, T. Uchiumi, T. Konno, T. Ebihara, T. Nakamura, and M. Wada Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome Hepatology 36 2002 1236 12345
93. V. Keitel, A.T. Nies, M. Brom, J. Hummel-Eisenbeiss, H. Spring, and D. Keppler A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2) Am J Physiol 284 2003 G165 G174
94. C. Spirli, M.H. Nathanson, R. Fiorotto, E. Duner, L.A. Denson, and J.M. Sanz Proinflammatory cytokines inhibit secretion in rat bile duct epithelium Gastroenterology 121 2001 156 169
95. C. Spirli, L. Fabris, E. Duner, R. Fiorotto, G. Ballardini, and T. Roskams Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes Gastroenterology 124 2003 737 753
96. N.O. Ku, X. Zhou, D.M. Toivola, and M.B. Omary The cytoskeleton of digestive epithelia in health and disease Am J Physiol 277 1999 G1108 G1137
97. D.A. Brown, and E. London Structure and function of sphingolipid- and cholesterol-rich membrane rafts J Biol Chem 275 2000 17221 17224