HTII-280, a biomarker specific to the apical plasma membrane of human lung alveolar type II cells

Journal of Histochemistry and Cytochemistry

Volumn 58, Issue 10, 2010, Pages 891-901

  Gonzalez, Robert F ^b   Allen, Lennell ^b   Gonzales, Linda ^c   Ballard, Philip L ^a   Dobbs, Leland G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Biomarker; HTII 280; Human pulmonary epithelium; Membrane protein; Type II cells

Indexed keywords

BIOLOGICAL MARKER; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN HTII 280; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL STRUCTURE; CELL VIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ALVEOLUS CELL TYPE 2; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; CELL SEPARATION; CHEMISTRY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFANT; ISOELECTRIC FOCUSING; ISOLATION AND PURIFICATION; LUNG ALVEOLUS; METABOLISM; MOLECULAR WEIGHT; MOUSE; RESPIRATORY TRACT MUCOSA; SOLUBILITY;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; CELL MEMBRANE; CELL SEPARATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; ISOELECTRIC FOCUSING; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MOLECULAR WEIGHT; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; SOLUBILITY;

EID: 77957319700     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.2010.956433     Document Type: Article

References (44)

1. Andreeva AV, Kutuzov MA, Voyno-Yasenetskaya TA (2007) Regulation of surfactant secretion in alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 293:L259-271
2. Baker DG, McDonald DM (1992) Distribution of catecholamine-containing nerves on blood vessels of the rat trachea. J Comp Neurol 325:38-46
3. Boylan GM, Pryde JG, Dobbs LG, McElroy MC (2001) Identification of a novel antigen on the apical surface of rat alveolar epithelial type II and Clara cells. Am J Physiol Lung Cell Mol Physiol 280:L1318-1326
4. Clegg GR, Tyrrell C, McKechnie SR, Beers MF, Harrison D, McElroy MC (2005) Coexpression of RTI40 with alveolar epithelial type II cell proteins in lungs following injury: identification of alveolar intermediate cell types. Am J Physiol Lung Cell Mol Physiol 289:L382-390
5. Deutscher M (1990) Guide to Protein Purification. Methods in Enzymology, vol. 182. London, Academic Press
6. Dobbs LG, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman AS (1998) Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci USA 95:2991-2996
7. Dobbs LG, Gonzalez R, Williams MC (1986) An improved method for isolating type II cells in high yield and purity. Am Rev Respir Dis 134:141-145
8. Dobbs LG, Gonzalez RF, Allen L, Froh DK (1999) HTI-56, an integral membrane protein specific to human alveolar type I cells. J Histochem Cytochem 47:129-137
9. Dobbs LG, Williams MC, Brandt AE (1985) Changes in biochemical characteristics and pattern of lectin binding of alveolar type II cells with time in culture. Biochim Biophys Acta 846:155-166
10. Dobbs LG, Williams MC, Gonzalez R (1988) Monoclonal antibodies specific to apical surfaces of rat alveolar type I cells bind to surfaces of cultured, but not freshly isolated, type II cells. Biochim Biophys Acta 970:146-156
11. Evans MJ, Cabral LJ, Stephens RJ, Freeman G (1975) Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2. Exp Mol Pathol 22:142-150
12. Fearon WF, Lee FH, Froelicher VF (1999) Does elevated cardiac troponin I in patients with unstable angina predict ischemia on stress testing? Am J Cardiol 84:1440-1442
13. Fehrenbach H, Kasper M, Tschernig T, Pan T, Schuh D, Shannon JM, Muller M, et al. (1999) Keratinocyte growth factor-induced hyperplasia of rat alveolar type II cells in vivo is resolved by differentiation into type I cells and by apoptosis. Eur Respir J 14:534-544
14. Foster C, Aktar A, Kopf D, Zhang P, Guttentag S (2004) Pepsinogen C: a type 2 cell-specific protease. Am J Physiol Lung Cell Mol Physiol 286:L382-387
15. Fullmer CS (1984) Identification of cysteine-containing peptides in protein digests by high-performance liquid chromatography. Anal Biochem 142:336-339
16. Gianazza E, Giorgio Righetti P (1980) Size and charge distribution of macromolecules in living systems. J Chromatogr A 193:1-8
17. Gonzalez R, Dobbs L (1997) Characterization and utility of a monoclonal antibody specific to the apical surface of rat alveolar type II cells. Mol Biol Cell 8:1981
18. Gonzalez R, Yang YH, Griffin C, Allen L, Tigue Z, Dobbs L (2005) Freshly isolated rat alveolar type I cells, type II cells, and cultured type II cells have distinct molecular phenotypes. Am J Physiol Lung Cell Mol Physiol 288:L179-189
19. Gonzalez RF, Allen L, Dobbs LG (2009) Rat alveolar type I cells proliferate, express OCT-4, and exhibit phenotypic plasticity in vitro. Am J Physiol Lung Cell Mol Physiol 297:L1045-1055
20. Inagaki N, Yamada K, Zhao L-X, Yamano G, Tanaka Y, Funahashi H, Zhou C-J, et al. (2004) Cloning, tissue distribution and function of ABCA transporters. Int Congr Ser 1262:578-581
21. Johnson MD, Bao HF, Helms MN, Chen XJ, Tigue Z, Jain L, Dobbs LG, et al. (2006) Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport. Proc Natl Acad Sci USA 103:4964-4969
22. Kalina M, Mason RJ, Shannon JM (1992) Surfactant protein C is expressed in alveolar type II cells but not in Clara cells of rat lung. Am J Respir Cell Mol Biol 6:594-600
23. Kasper M, Behrens J, Schuh D, Müller M (1995) Distribution of E-cadherin and Ep-CAM in the human lung during development and after injury. Histochem Cell Biol 103:281-286
24. Kononen J, Bubendorf L, Kallioniemi A, Bärlund M, Schraml P, Leighton S, Torhorst J, et al. (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4:844-847
25. Koslowski R, Dobbs LG,Wenzel KW, Schuh D, Muller M, KasperM (1998) Loss of immunoreactivity for RTI40, a type I cell-specific protein in the alveolar epithelium of rat lungs with bleomycin-induced fibrosis. Eur Respir J 12:1397-1403
26. Matute-Bello G, Frevert CW, Martin TR (2008) Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 295:L379-399
27. McElroy MC, Pittet JF, Hashimoto S, Allen L, Wiener-Kronish JP, Dobbs LG (1995) A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia. Am J Physiol 268:L181-186
28. McElroy MC,Wiener-Kronish JP,Miyazaki H, Sawa T, Modelska K, Dobbs LG, Pittet JF (1997) Nitric oxide attenuates lung endothelial injury caused by sublethal hyperoxia in rats. Am J Physiol 272:L631-638
29. Newman V, Gonzalez R, Matthay M, Dobbs L (1999) HTI-56, an integral apical membrane protein of the human alveolar type I cell, is a biochemical marker of acute lung injury. Chest 116:35S-36S
30. Newman V, Gonzalez RF, Matthay MA, Dobbs LG (2000) A novel alveolar type I cell-specific biochemical marker of human acute lung injury. Am J Respir Crit Care Med 161:990-995
31. Nose K, Saito H, Kuroki T (1990) Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells. Cell Growth Differ 1:511-518
32. Ramirez MI, Cao YX, Williams MC (1999) 1.3 Kilobases of the lung type I cell TI alpha gene promoter mimics endogenous gene expression patterns during development but lacks sequences to enhance expression in perinatal and adult lung. Dev Dyn 215:319-331
33. Richards L (2009) Biomarkers: rapid urine test for kidney disease. Nat Rev Nephrol 5:548-548
34. Rishi AK, Joyce-Brady M, Fisher J, Dobbs LG, Floros J, VanderSpek J, Brody JS, et al. (1995) Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives. Dev Biol 167:294-306.
35. Salaun B, de Saint-Vis B, Clair-Moninot V, Pin JJ, Barthélemy- Dubois C, Kissenpfennig A, Peronne C, et al. (2003) Cloning and characterization of the mouse homologue of the human dendritic cell maturation marker CD208/DC-LAMP. Eur J Immunol 33:2619-2629
36. Serrano-Mollar A, Nacher M, Gay-Jordi G, Closa D, Xaubet A, Bulbena O (2007) Intratracheal transplantation of alveolar type II cells reverses bleomycin-induced lung fibrosis. Am J Respir Crit Care Med 176:1261-1268
37. Simon R, Sauter G (2003) Tissue microarray (TMA) applications: implications for molecular medicine. Expert Rev Mol Med 5:1-12
38. Stone KC, Mercer RR, Freeman BA, Chang LY, Crapo JD (1992) Distribution of lung cell numbers and volumes between alveolar and nonalveolar tissue. Am Rev Respir Dis 146:454-456
39. Tarnok A, Ulrich H, Bocsi J (2009) Phenotypes of stem cells from diverse origin. Cytometry A 77:6-10
40. Tokuyasu KT (1989) Use of poly(vinylpyrrolidone) and poly(vinyl alcohol) for cryoultramicrotomy. Histochem J 21:163-171
41. Walker S, Williams M, Benson B (1986) Immunocytochemical localization of the major surfactant apoproteins in type II cells, Clara cells, and alveolar macrophages of rat lung. J Histochem Cytochem 34:1137-1148
42. Wetterwald A, Hofstetter W, Cecchini MG, Lanske B, Wagner C, Fleisch H, Atkinson M (1996) Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone 18:125-132
43. Wright JR (2005) Immunoregulatory functions of surfactant proteins. Nat Rev Immunol 5:58-68
44. Wright JR, Dobbs LG (1991) Regulation of pulmonary surfactant secretion and clearance. Annu Rev Physiol 53:395-414