PCB126 exposure disrupts zebrafish ventricular and branchial but not early neural crest development

Toxicological Sciences

Volumn 106, Issue 1, 2008, Pages 193-205

  Grimes, Adrian C ^a,b   Erwin, Kyle N ^b   Stadt, Harriett A ^b   Hunter, Ginger L ^b   Gefroh, Holly A ^c   Tsai, Huai Jen ^d   Kirby, Margaret L ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c Qualyst Inc   (United States)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Aryl hydrocarbon receptor; Branchial cartilages; Cardiotoxicity; PCB126; Proliferation; Valvulogenesis; Ventricular development; Zebrafish

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; BETA ACTIN; CYTOCHROME P450 1A1; DIOXIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PIFITHRIN ALPHA; POLYCHLORINATED BIPHENYL; PROTEIN P53; TROPONIN T;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRANCHIAL DEFECT; CARDIOVASCULAR MALFORMATION; CELL COUNT; CELL MIGRATION; CELL SIZE; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; EMBRYO PATTERN FORMATION; EMBRYOTOXICITY; ENVIRONMENTAL EXPOSURE; EXPERIMENTAL MODEL; HEART DEVELOPMENT; HEART FUNCTION; HEART VENTRICLE; HYPOPLASTIC LEFT HEART SYNDROME; JAW MALFORMATION; NEURAL CREST; NEURAL CREST CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PHENOTYPE; ZEBRA FISH;

ABNORMALITIES, MULTIPLE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BENZOTHIAZOLES; BODY PATTERNING; BRANCHIAL REGION; CELL DEATH; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; ENVIRONMENTAL POLLUTANTS; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; JAW ABNORMALITIES; MORPHOLINES; NEURAL CREST; OLIGONUCLEOTIDES; PHENOTYPE; POLYCHLORINATED BIPHENYLS; TIME FACTORS; TOLUENE; TROPONIN T; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH;

BULBUS; DANIO RERIO;

EID: 54349128674     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn154     Document Type: Article

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