메뉴 건너뛰기




Volumn 34, Issue 2, 2012, Pages 275-283

Triazole induced concentration-related gene signatures in rat whole embryo culture

Author keywords

Cyp26a1; Cyp51; Embryo; Gene expression; Retinoic acid; Toxicogenomics; Triazoles; Whole embryo culture

Indexed keywords

CHOLESTEROL; CYPROCONAZOLE; FLUSILAZOLE; RETINOIC ACID; STEROID; TRIADIMEFON; TRIAZOLE; UNCLASSIFIED DRUG;

EID: 84864023778     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2012.05.088     Document Type: Article
Times cited : (50)

References (52)
  • 2
    • 84857985424 scopus 로고    scopus 로고
    • Transcriptomic analysis of neurulation and early organogenesis in rat embryos: an in vivo and ex vivo comparison
    • Robinson J.F., Verhoef A., Piersma A.H. Transcriptomic analysis of neurulation and early organogenesis in rat embryos: an in vivo and ex vivo comparison. Toxicological Sciences 2012, 126:255-266.
    • (2012) Toxicological Sciences , vol.126 , pp. 255-266
    • Robinson, J.F.1    Verhoef, A.2    Piersma, A.H.3
  • 3
    • 84864003529 scopus 로고    scopus 로고
    • INVITTOX Protocol 123. Embryotoxicity testing in postimplantation rat whole embryo culture: method of Piersma. ECVAM DB-ALM;
    • INVITTOX Protocol 123. Embryotoxicity testing in postimplantation rat whole embryo culture: method of Piersma. ECVAM DB-ALM; 1999.
    • (1999)
  • 4
    • 0019806298 scopus 로고
    • Quantitation of rat embryonic development in vitro: a morphological scoring system
    • Brown N.A., Fabro S. Quantitation of rat embryonic development in vitro: a morphological scoring system. Teratology 1981, 24:65-78.
    • (1981) Teratology , vol.24 , pp. 65-78
    • Brown, N.A.1    Fabro, S.2
  • 5
    • 0025367652 scopus 로고
    • Morphogenesis and quantification of the development of post-implantation mouse embryos
    • Van Maele-Fabry G., Delhaise F., Picard J.J. Morphogenesis and quantification of the development of post-implantation mouse embryos. Toxicology In Vitro 1990, 4:149-156.
    • (1990) Toxicology In Vitro , vol.4 , pp. 149-156
    • Van Maele-Fabry, G.1    Delhaise, F.2    Picard, J.J.3
  • 6
    • 8744293605 scopus 로고    scopus 로고
    • Validation of the postimplantation rat whole-embryo culture test in the international ECVAM validation study on three in vitro embryotoxicity tests
    • Piersma A.H., Genschow E., Verhoef A., Spanjersberg M.Q., Brown N.A., Brady M., et al. Validation of the postimplantation rat whole-embryo culture test in the international ECVAM validation study on three in vitro embryotoxicity tests. Alternatives to Laboratory Animals 2004, 32:275-307.
    • (2004) Alternatives to Laboratory Animals , vol.32 , pp. 275-307
    • Piersma, A.H.1    Genschow, E.2    Verhoef, A.3    Spanjersberg, M.Q.4    Brown, N.A.5    Brady, M.6
  • 9
  • 12
    • 84857947576 scopus 로고    scopus 로고
    • A comparison of gene expression responses in rat whole embryo culture and in vivo: time-dependent retinoic acid-induced teratogenic response
    • Robinson J.F., Verhoef A., Pennings J.L., Pronk T.E., Piersma A.H. A comparison of gene expression responses in rat whole embryo culture and in vivo: time-dependent retinoic acid-induced teratogenic response. Toxicological Sciences 2012, 126:242-254.
    • (2012) Toxicological Sciences , vol.126 , pp. 242-254
    • Robinson, J.F.1    Verhoef, A.2    Pennings, J.L.3    Pronk, T.E.4    Piersma, A.H.5
  • 14
    • 66049136991 scopus 로고    scopus 로고
    • Toxicogenomic effects common to triazole antifungals and conserved between rats and humans
    • Goetz A.K., Dix D.J. Toxicogenomic effects common to triazole antifungals and conserved between rats and humans. Toxicology and Applied Pharmacology 2009, 238:80-89.
    • (2009) Toxicology and Applied Pharmacology , vol.238 , pp. 80-89
    • Goetz, A.K.1    Dix, D.J.2
  • 15
    • 33746914451 scopus 로고    scopus 로고
    • Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides
    • Tully D.B., Bao W., Goetz A.K., Blystone C.R., Ren H., Schmid J.E., et al. Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides. Toxicology and Applied Pharmacology 2006, 215:260-273.
    • (2006) Toxicology and Applied Pharmacology , vol.215 , pp. 260-273
    • Tully, D.B.1    Bao, W.2    Goetz, A.K.3    Blystone, C.R.4    Ren, H.5    Schmid, J.E.6
  • 16
    • 33845656069 scopus 로고    scopus 로고
    • Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat
    • Goetz A.K., Ren H., Schmid J.E., Blystone C.R., Thillainadarajah I., Best D.S., et al. Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat. Toxicological Sciences 2007, 95:227-239.
    • (2007) Toxicological Sciences , vol.95 , pp. 227-239
    • Goetz, A.K.1    Ren, H.2    Schmid, J.E.3    Blystone, C.R.4    Thillainadarajah, I.5    Best, D.S.6
  • 17
    • 77955920494 scopus 로고    scopus 로고
    • Are azole fungicides a teratogenic risk for human conceptus
    • Giavini E., Menegola E. Are azole fungicides a teratogenic risk for human conceptus. Toxicology Letters 2010, 198:106-111.
    • (2010) Toxicology Letters , vol.198 , pp. 106-111
    • Giavini, E.1    Menegola, E.2
  • 18
    • 0028962772 scopus 로고
    • Developmental toxicity of cyproconazole, an inhibitor of fungal ergosterol biosynthesis, in the rat
    • Machera K. Developmental toxicity of cyproconazole, an inhibitor of fungal ergosterol biosynthesis, in the rat. Bulletin of Environment Contamination and Toxicology 1995, 54:363-369.
    • (1995) Bulletin of Environment Contamination and Toxicology , vol.54 , pp. 363-369
    • Machera, K.1
  • 22
    • 79960846481 scopus 로고    scopus 로고
    • Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals
    • Hermsen S.A., Pronk T.E., van den Brandhof E.J., van der Ven L.T., Piersma A.H. Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals. Reproductive Toxicology 2011, 32:245-252.
    • (2011) Reproductive Toxicology , vol.32 , pp. 245-252
    • Hermsen, S.A.1    Pronk, T.E.2    van den Brandhof, E.J.3    van der Ven, L.T.4    Piersma, A.H.5
  • 23
    • 84860154353 scopus 로고    scopus 로고
    • Concentration-response analysis of differential gene expression in the zebrafish embryotoxicity test following flusilazole exposure
    • Hermsen S.A., Pronk T.E., van den Brandhof E.J., van der Ven L.T., Piersma A.H. Concentration-response analysis of differential gene expression in the zebrafish embryotoxicity test following flusilazole exposure. Toxicological Sciences 2012, 127:303-312.
    • (2012) Toxicological Sciences , vol.127 , pp. 303-312
    • Hermsen, S.A.1    Pronk, T.E.2    van den Brandhof, E.J.3    van der Ven, L.T.4    Piersma, A.H.5
  • 24
    • 0842263746 scopus 로고    scopus 로고
    • Relationship between hindbrain segmentation, neural crest cell migration and branchial arch abnormalities in rat embryos exposed to fluconazole and retinoic acid in vitro
    • Menegola E., Broccia M.L., Di Renzo F., Massa V., Giavini E. Relationship between hindbrain segmentation, neural crest cell migration and branchial arch abnormalities in rat embryos exposed to fluconazole and retinoic acid in vitro. Reproductive Toxicology 2004, 18:121-130.
    • (2004) Reproductive Toxicology , vol.18 , pp. 121-130
    • Menegola, E.1    Broccia, M.L.2    Di Renzo, F.3    Massa, V.4    Giavini, E.5
  • 25
    • 20444493080 scopus 로고    scopus 로고
    • Study on the common teratogenic pathway elicited by the fungicides triazole-derivatives
    • Menegola E., Broccia M.L., Di Renzo F., Massa V., Giavini E. Study on the common teratogenic pathway elicited by the fungicides triazole-derivatives. Toxicology In Vitro 2005, 19:737-748.
    • (2005) Toxicology In Vitro , vol.19 , pp. 737-748
    • Menegola, E.1    Broccia, M.L.2    Di Renzo, F.3    Massa, V.4    Giavini, E.5
  • 26
    • 79955604503 scopus 로고    scopus 로고
    • Comparison of the mouse embryonic stem cell test, the rat whole embryo culture and the zebrafish embryotoxicity test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles
    • de Jong E., Barenys M., Hermsen S.A., Verhoef A., Ossendorp B.C., Bessems J.G., et al. Comparison of the mouse embryonic stem cell test, the rat whole embryo culture and the zebrafish embryotoxicity test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles. Toxicology and Applied Pharmacology 2011, 253:103-111.
    • (2011) Toxicology and Applied Pharmacology , vol.253 , pp. 103-111
    • de Jong, E.1    Barenys, M.2    Hermsen, S.A.3    Verhoef, A.4    Ossendorp, B.C.5    Bessems, J.G.6
  • 28
    • 29144535372 scopus 로고    scopus 로고
    • Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
    • Dai M., Wang P., Boyd A.D., Kostov G., Athey B., Jones E.G., et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Research 2005, 33:e175.
    • (2005) Nucleic Acids Research , vol.33
    • Dai, M.1    Wang, P.2    Boyd, A.D.3    Kostov, G.4    Athey, B.5    Jones, E.G.6
  • 30
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society 1995, B 57:289-300.
    • (1995) Journal of the Royal Statistical Society , vol.B 57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 34
    • 38149075215 scopus 로고    scopus 로고
    • BMDExpress: a software tool for the benchmark dose analyses of genomic data
    • Yang L., Allen B.C., Thomas R.S. BMDExpress: a software tool for the benchmark dose analyses of genomic data. BMC Genomics 2007, 8:387.
    • (2007) BMC Genomics , vol.8 , pp. 387
    • Yang, L.1    Allen, B.C.2    Thomas, R.S.3
  • 43
    • 79651475788 scopus 로고    scopus 로고
    • Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test
    • van Dartel D.A., Pennings J.L., Robinson J.F., Kleinjans J.C., Piersma A.H. Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test. Toxicology Letters 2011, 201:143-151.
    • (2011) Toxicology Letters , vol.201 , pp. 143-151
    • van Dartel, D.A.1    Pennings, J.L.2    Robinson, J.F.3    Kleinjans, J.C.4    Piersma, A.H.5
  • 44
    • 33749667750 scopus 로고    scopus 로고
    • Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles
    • Trosken E.R., Adamska M., Arand M., Zarn J.A., Patten C., Volkel W., et al. Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology 2006, 228:24-32.
    • (2006) Toxicology , vol.228 , pp. 24-32
    • Trosken, E.R.1    Adamska, M.2    Arand, M.3    Zarn, J.A.4    Patten, C.5    Volkel, W.6
  • 46
    • 79952236202 scopus 로고    scopus 로고
    • Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay
    • He M., Kratz L.E., Michel J.J., Vallejo A.N., Ferris L., Kelley R.I., et al. Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay. Journal of Clinical Investigation 2011, 121:976-984.
    • (2011) Journal of Clinical Investigation , vol.121 , pp. 976-984
    • He, M.1    Kratz, L.E.2    Michel, J.J.3    Vallejo, A.N.4    Ferris, L.5    Kelley, R.I.6
  • 47
    • 80051700976 scopus 로고    scopus 로고
    • Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome
    • Keber R., Motaln H., Wagner K.D., Debeljak N., Rassoulzadegan M., Acimovic J., et al. Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome. Journal of Biological Chemistry 2011, 286:29086-29097.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 29086-29097
    • Keber, R.1    Motaln, H.2    Wagner, K.D.3    Debeljak, N.4    Rassoulzadegan, M.5    Acimovic, J.6
  • 48
    • 0035862977 scopus 로고    scopus 로고
    • The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures
    • Abu-Abed S., Dolle P., Metzger D., Beckett B., Chambon P., Petkovich M. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes and Development 2001, 15:226-240.
    • (2001) Genes and Development , vol.15 , pp. 226-240
    • Abu-Abed, S.1    Dolle, P.2    Metzger, D.3    Beckett, B.4    Chambon, P.5    Petkovich, M.6
  • 49
    • 80053894104 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26)
    • Gomaa M.S., Bridgens C.E., Veal G.J., Redfern C.P., Brancale A., Armstrong J.L., et al. Synthesis and biological evaluation of 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26). Journal of Medicinal Chemistry 2011, 54:6803-6811.
    • (2011) Journal of Medicinal Chemistry , vol.54 , pp. 6803-6811
    • Gomaa, M.S.1    Bridgens, C.E.2    Veal, G.J.3    Redfern, C.P.4    Brancale, A.5    Armstrong, J.L.6
  • 50
    • 84864010821 scopus 로고    scopus 로고
    • 2 D-QSAR studies on CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1 H-triazoles
    • Yadav M. 2 D-QSAR studies on CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1 H-triazoles. Bioinformation 2011, 7:388-392.
    • (2011) Bioinformation , vol.7 , pp. 388-392
    • Yadav, M.1
  • 51
    • 62549107006 scopus 로고    scopus 로고
    • Fluconazole alters CYP26 gene expression in mouse embryos
    • Tiboni G.M., Marotta F., Carletti E. Fluconazole alters CYP26 gene expression in mouse embryos. Reproductive Toxicology 2009, 27:199-202.
    • (2009) Reproductive Toxicology , vol.27 , pp. 199-202
    • Tiboni, G.M.1    Marotta, F.2    Carletti, E.3
  • 52
    • 73849129892 scopus 로고    scopus 로고
    • Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism
    • Feng L., Hernandez R.E., Waxman J.S., Yelon D., Moens C.B. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Developmental Biology 2010, 338:1-14.
    • (2010) Developmental Biology , vol.338 , pp. 1-14
    • Feng, L.1    Hernandez, R.E.2    Waxman, J.S.3    Yelon, D.4    Moens, C.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.