메뉴 건너뛰기




Volumn 34, Issue 1, 2003, Pages 85-90

Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells

Author keywords

[No Author keywords available]

Indexed keywords

MERCAPTOPURINE; METHOTREXATE;

EID: 0037738513     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1151     Document Type: Article
Times cited : (231)

References (29)
  • 1
    • 0032572912 scopus 로고    scopus 로고
    • Acute lymphoblastic leukemia
    • Pui, C.H. & Evans, W.E. Acute lymphoblastic leukemia. N. Engl. J. Med. 339, 605-615 (1998).
    • (1998) N. Engl. J. Med. , vol.339 , pp. 605-615
    • Pui, C.H.1    Evans, W.E.2
  • 2
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans, W.E. & Relling, M.V. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487-491 (1999).
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 3
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • Evans, W.E. & McLeod, H.L. Pharmacogenomics - drug disposition, drug targets, and side effects. N. Engl. J. Med. 348, 538-549 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 4
    • 0035473994 scopus 로고    scopus 로고
    • Childhood acute lymphoblastic leukaemia - Current status and future perspectives
    • Pui, C.H., Campana, D. & Evans, W.E. Childhood acute lymphoblastic leukaemia - current status and future perspectives. Lancet Oncol. 2, 597-607 (2001).
    • (2001) Lancet Oncol. , vol.2 , pp. 597-607
    • Pui, C.H.1    Campana, D.2    Evans, W.E.3
  • 5
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub, T.R. et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537 (1999).
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1
  • 6
    • 18544375333 scopus 로고    scopus 로고
    • MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
    • Armstrong, S.A. et al. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat. Genet. 30, 41-47 (2002).
    • (2002) Nat. Genet. , vol.30 , pp. 41-47
    • Armstrong, S.A.1
  • 7
    • 17144474314 scopus 로고    scopus 로고
    • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    • Ferrando, A.A. et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1, 75-87 (2002).
    • (2002) Cancer Cell , vol.1 , pp. 75-87
    • Ferrando, A.A.1
  • 8
    • 19044399684 scopus 로고    scopus 로고
    • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
    • Yeoh, E.-J. et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 1, 133-143 (2002).
    • (2002) Cancer Cell , vol.1 , pp. 133-143
    • Yeoh, E.-J.1
  • 9
    • 0034088857 scopus 로고    scopus 로고
    • A gene expression database for the molecular pharmacology of cancer
    • Scherf, U. et al. A gene expression database for the molecular pharmacology of cancer. Nat. Genet. 24, 236-244 (2000).
    • (2000) Nat. Genet. , vol.24 , pp. 236-244
    • Scherf, U.1
  • 10
    • 0031193385 scopus 로고    scopus 로고
    • Differential induction of apoptosis on human lymphoblastic leukemia Nalm-6 and Molt-4 cells by various antitumor drugs
    • Tsurusawa, M., Saeki, K. & Fujimoto, T. Differential induction of apoptosis on human lymphoblastic leukemia Nalm-6 and Molt-4 cells by various antitumor drugs. Int. J. Hematol. 66, 79-88 (1997).
    • (1997) Int. J. Hematol. , vol.66 , pp. 79-88
    • Tsurusawa, M.1    Saeki, K.2    Fujimoto, T.3
  • 11
    • 0024554561 scopus 로고
    • The purine path to chemotherapy
    • Elion, G.B. The purine path to chemotherapy. Science 244, 41-47 (1989).
    • (1989) Science , vol.244 , pp. 41-47
    • Elion, G.B.1
  • 12
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology
    • The Gene Ontology Consortium
    • Ashburner, M. et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25, 25-29 (2000).
    • (2000) Nat. Genet. , vol.25 , pp. 25-29
    • Ashburner, M.1
  • 13
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M.B. & Lim, D.S. The many substrates and functions of ATM. Nat. Rev. Mol. Cell Biol. 1, 179-186 (2000).
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 14
    • 0030925565 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
    • Baskaran, R. et al. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature 387, 516-519 (1997).
    • (1997) Nature , vol.387 , pp. 516-519
    • Baskaran, R.1
  • 15
    • 0006889222 scopus 로고
    • Accumulation of DNA strand breaks and methotrexate cytotoxicity
    • Li, J.C. & Kaminskas, E. Accumulation of DNA strand breaks and methotrexate cytotoxicity. Proc. Natl. Acad. Sci. USA 81, 5694-5698 (1984).
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 5694-5698
    • Li, J.C.1    Kaminskas, E.2
  • 16
    • 0023880857 scopus 로고
    • Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5,8-dideazafolic acid
    • Lorico, A. et al. Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5,8-dideazafolic acid. Cancer Res. 48, 2036-2041 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 2036-2041
    • Lorico, A.1
  • 17
    • 0028204160 scopus 로고
    • DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
    • Nelson, W.G. & Kastan, M.B. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell Biol. 14, 1815-1823 (1994).
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1815-1823
    • Nelson, W.G.1    Kastan, M.B.2
  • 18
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist, C.J. & Kastan, M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421, 499-506 (2003).
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 19
    • 19144365420 scopus 로고    scopus 로고
    • Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16
    • Wijnen, J. et al. Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. Am. J. Hum. Genet. 58, 300-307 (1996).
    • (1996) Am. J. Hum. Genet. , vol.58 , pp. 300-307
    • Wijnen, J.1
  • 20
    • 18144441195 scopus 로고    scopus 로고
    • Transcripts with splicings of exons 15 and 16 of the hMLH1 gene in normal lymphocytes: Implications in RNA-based mutation screening of hereditary non-polyposis colorectal cancer
    • Palmirotta, R. et al. Transcripts with splicings of exons 15 and 16 of the hMLH1 gene in normal lymphocytes: implications in RNA-based mutation screening of hereditary non-polyposis colorectal cancer. Eur. J. Cancer 34, 927-930 (1998).
    • (1998) Eur. J. Cancer , vol.34 , pp. 927-930
    • Palmirotta, R.1
  • 21
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong, J.G. et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 399, 806-809 (1999).
    • (1999) Nature , vol.399 , pp. 806-809
    • Gong, J.G.1
  • 22
    • 0029822592 scopus 로고    scopus 로고
    • Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
    • Swann, P.F. et al. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science 273, 1109-1111 (1996).
    • (1996) Science , vol.273 , pp. 1109-1111
    • Swann, P.F.1
  • 23
    • 0031730097 scopus 로고    scopus 로고
    • Drug target validation and identification of secondary drug target effects using DNA microarrays
    • Marton, M.J. et al. Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat. Med. 4, 1293-1301 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 1293-1301
    • Marton, M.J.1
  • 24
    • 13844311931 scopus 로고    scopus 로고
    • Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
    • Sotiriou, C. et al. Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer. Breast Cancer Res. 4, R3 (2002).
    • (2002) Breast Cancer Res. , vol.4
    • Sotiriou, C.1
  • 25
    • 0027417198 scopus 로고
    • 6-Mercaptopurine: Cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts
    • Bokkerink, J.R et al. 6-Mercaptopurine: cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts. Biochem. Pharmacol. 45, 1455-1463 (1993).
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 1455-1463
    • Bokkerink, J.R.1
  • 26
    • 0029846176 scopus 로고    scopus 로고
    • Intrinsic and acquired resistance to methotrexate in acute leukemia
    • Gorlick, R. et al. Intrinsic and acquired resistance to methotrexate in acute leukemia. N. Engl. J. Med. 335, 1041-1048 (1996).
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1041-1048
    • Gorlick, R.1
  • 27
    • 0030034467 scopus 로고    scopus 로고
    • Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate
    • Masson, E. et al. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate. J. Clin. Invest. 97, 73-80 (1996).
    • (1996) J. Clin. Invest. , vol.97 , pp. 73-80
    • Masson, E.1
  • 28
    • 0028063423 scopus 로고
    • Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
    • Synold, T.W. et al. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. J. Clin. Invest. 94, 1996-2001 (1994).
    • (1994) J. Clin. Invest. , vol.94 , pp. 1996-2001
    • Synold, T.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.