-
1
-
-
33744548450
-
Myelin biogenesis: sorting out protein trafficking
-
Anitei, M., and Pfeiffer, S. E. (2006). Myelin biogenesis: sorting out protein trafficking. Curr. Biol. 16, R418-R421. doi: 10.1016/j.cub.2006.05.010.
-
(2006)
Curr. Biol
, vol.16
, pp. R418-R421
-
-
Anitei, M.1
Pfeiffer, S.E.2
-
2
-
-
84861222698
-
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells
-
Aragon, I. V., Barrington, R. A., Jackowski, S., Mori, K., and Brewer, J. W. (2012). The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. Mol. Immunol. 51, 347-355. doi: 10.1016/j.molimm.2012.04.001.
-
(2012)
Mol. Immunol
, vol.51
, pp. 347-355
-
-
Aragon, I.V.1
Barrington, R.A.2
Jackowski, S.3
Mori, K.4
Brewer, J.W.5
-
3
-
-
84875235453
-
Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity
-
Atkins, C., Liu, Q., Minthorn, E., Zhang, S. Y., Figueroa, D. J., Moss, K., et al. (2013). Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity. Cancer. Res. 73, 1993-2002. doi: 10.1158/0008-5472.CAN-12-3109.
-
(2013)
Cancer. Res
, vol.73
, pp. 1993-2002
-
-
Atkins, C.1
Liu, Q.2
Minthorn, E.3
Zhang, S.Y.4
Figueroa, D.J.5
Moss, K.6
-
4
-
-
84866905708
-
Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK)
-
Axten, J. M., Medina, J. R., Feng, Y., Shu, A., Romeril, S. P., Grant, S. W., et al. (2012). Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J. Med. Chem. 55, 7193-7207. doi: 10.1021/jm300713s.
-
(2012)
J. Med. Chem
, vol.55
, pp. 7193-7207
-
-
Axten, J.M.1
Medina, J.R.2
Feng, Y.3
Shu, A.4
Romeril, S.P.5
Grant, S.W.6
-
5
-
-
33847223756
-
Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis
-
Balabanov, R., Strand, K., Goswami, R., McMahon, E., Begolka, W., Miller, S. D., et al. (2007). Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. J. Neurosci. 27, 2013-2024. doi: 10.1523/JNEUROSCI.4689-06.2007.
-
(2007)
J. Neurosci
, vol.27
, pp. 2013-2024
-
-
Balabanov, R.1
Strand, K.2
Goswami, R.3
McMahon, E.4
Begolka, W.5
Miller, S.D.6
-
6
-
-
84877872994
-
Oligodendroglia and neurotrophic factors in neurodegeneration
-
Bankston, A. N., Mandler, M. D., and Feng, Y. (2013). Oligodendroglia and neurotrophic factors in neurodegeneration. Neurosci. Bull. 29, 216-228. doi: 10.1007/s12264-013-1321-3.
-
(2013)
Neurosci. Bull
, vol.29
, pp. 216-228
-
-
Bankston, A.N.1
Mandler, M.D.2
Feng, Y.3
-
7
-
-
1642281535
-
Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
-
Barnett, M. H., and Prineas, J. W. (2004). Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55, 458-468. doi: 10.1002/ana.20016.
-
(2004)
Ann. Neurol
, vol.55
, pp. 458-468
-
-
Barnett, M.H.1
Prineas, J.W.2
-
8
-
-
35549010987
-
The origin and application of experimental autoimmune encephalomyelitis
-
Baxter, A. G. (2007). The origin and application of experimental autoimmune encephalomyelitis. Nat. Rev. Immunol. 7, 904-912. doi: 10.1038/nri2190.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 904-912
-
-
Baxter, A.G.1
-
9
-
-
67650000500
-
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum
-
Bommiasamy, H., Back, S. H., Fagone, P., Lee, K., Meshinchi, S., Vink, E., et al. (2009). ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum. J. Cell. Sci. 122, 1626-1636. doi: 10.1242/jcs.045625.
-
(2009)
J. Cell. Sci
, vol.122
, pp. 1626-1636
-
-
Bommiasamy, H.1
Back, S.H.2
Fagone, P.3
Lee, K.4
Meshinchi, S.5
Vink, E.6
-
10
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce, M., Bryant, K. F., Jousse, C., Long, K., Harding, H. P., Scheuner, D., et al. (2005). A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 307, 935-939. doi: 10.1126/science.1101902.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
-
11
-
-
77649192930
-
Oligodendrocytes: biology and pathology
-
Bradl, M., and Lassmann, H. (2010). Oligodendrocytes: biology and pathology. Acta Neuropathol. 119, 37-53. doi: 10.1007/s00401-009-0601-5.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 37-53
-
-
Bradl, M.1
Lassmann, H.2
-
12
-
-
12344256887
-
Building an antibody factory: a job for the unfolded protein response
-
Brewer, J. W., and Hendershot, L. M. (2005). Building an antibody factory: a job for the unfolded protein response. Nat. Immunol. 6, 23-29. doi: 10.1038/ni1149.
-
(2005)
Nat. Immunol
, vol.6
, pp. 23-29
-
-
Brewer, J.W.1
Hendershot, L.M.2
-
13
-
-
84903795970
-
Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease
-
Cao, S. S., and Kaufman, R. J. (2014). Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease. Antioxid. Redox Signal. 21, 396-413. doi: 10.1089/ars.2014.5851.
-
(2014)
Antioxid. Redox Signal
, vol.21
, pp. 396-413
-
-
Cao, S.S.1
Kaufman, R.J.2
-
14
-
-
2642538541
-
Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2 alpha in the central nervous system of SJL mice with experimental allergic encephalomyelitis
-
Chakrabarty, A., Danley, M. M., and LeVine, S. M. (2004). Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2 alpha in the central nervous system of SJL mice with experimental allergic encephalomyelitis. J. Neurosci. Res. 76, 822-833. doi: 10.1002/jnr.20125.
-
(2004)
J. Neurosci. Res
, vol.76
, pp. 822-833
-
-
Chakrabarty, A.1
Danley, M.M.2
LeVine, S.M.3
-
15
-
-
19344369610
-
Quantifying immunohistochemical staining of phospho-eIF2alpha, heme oxygenase-2 and NADPH cytochrome P450 reductase in oligodendrocytes during experimental autoimmune encephalomyelitis
-
Chakrabarty, A., Fleming, K. K., Marquis, J. G., and LeVine, S. M. (2005). Quantifying immunohistochemical staining of phospho-eIF2alpha, heme oxygenase-2 and NADPH cytochrome P450 reductase in oligodendrocytes during experimental autoimmune encephalomyelitis. J. Neurosci. Methods 144, 227-234. doi: 10.1016/j.jneumeth.2004.11.010.
-
(2005)
J. Neurosci. Methods
, vol.144
, pp. 227-234
-
-
Chakrabarty, A.1
Fleming, K.K.2
Marquis, J.G.3
LeVine, S.M.4
-
16
-
-
84886749523
-
IRE1: ER stress sensor and cell fate executor
-
Chen, Y., and Brandizzi, F. (2013). IRE1: ER stress sensor and cell fate executor. Trends Cell Biol. 23, 547-555. doi: 10.1016/j.tcb.2013.06.005.
-
(2013)
Trends Cell Biol
, vol.23
, pp. 547-555
-
-
Chen, Y.1
Brandizzi, F.2
-
17
-
-
84863229691
-
Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo
-
Colla, E., Jensen, P. H., Pletnikova, O., Troncoso, J. C., Glabe, C., and Lee, M. K. (2012). Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo. J. Neurosci. 32, 3301-3305. doi: 10.1523/JNEUROSCI.5368-11.2012.
-
(2012)
J. Neurosci
, vol.32
, pp. 3301-3305
-
-
Colla, E.1
Jensen, P.H.2
Pletnikova, O.3
Troncoso, J.C.4
Glabe, C.5
Lee, M.K.6
-
18
-
-
0030135421
-
Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development
-
Corbin, J. G., Kelly, D., Rath, E. M., Baerwald, K. D., Suzuki, K., and Popko, B. (1996). Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development. Mol. Cell Neurosci. 7, 354-370. doi: 10.1006/mcne.1996.0026.
-
(1996)
Mol. Cell Neurosci
, vol.7
, pp. 354-370
-
-
Corbin, J.G.1
Kelly, D.2
Rath, E.M.3
Baerwald, K.D.4
Suzuki, K.5
Popko, B.6
-
19
-
-
79951660345
-
Measuring signaling by the unfolded protein response
-
Cox, D. J., Strudwick, N., Ali, A. A., Paton, A. W., Paton, J. C., and Schröder, M. (2011). Measuring signaling by the unfolded protein response. Methods Enzymol. 491, 261-292. doi: 10.1016/B978-0-12-385928-0.00015-8.
-
(2011)
Methods Enzymol
, vol.491
, pp. 261-292
-
-
Cox, D.J.1
Strudwick, N.2
Ali, A.A.3
Paton, A.W.4
Paton, J.C.5
Schröder, M.6
-
20
-
-
33645980003
-
Endoplasmic reticulum: a metabolic compartment
-
Csala, M., Bánhegyi, G., and Benedetti, A. (2006). Endoplasmic reticulum: a metabolic compartment. FEBS Lett. 580, 2160-2165. doi: 10.1016/j.febslet.2006.03.050.
-
(2006)
FEBS Lett
, vol.580
, pp. 2160-2165
-
-
Csala, M.1
Bánhegyi, G.2
Benedetti, A.3
-
21
-
-
79959503183
-
Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis
-
Cunnea, P., Mháille, A. N., McQuaid, S., Farrell, M., McMahon, J., and Fitz Gerald, U. (2011). Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis. Mult. Scler. 17, 808-818. doi: 10.1177/1352458511399114.
-
(2011)
Mult. Scler
, vol.17
, pp. 808-818
-
-
Cunnea, P.1
Mháille, A.N.2
McQuaid, S.3
Farrell, M.4
McMahon, J.5
Fitz Gerald, U.6
-
22
-
-
0037328719
-
Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains
-
Cwiklinska, H., Mycko, M. P., Luvsannorov, O., Walkowiak, B., Brosnan, C. F., Raine, C. S., et al. (2003). Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains. Int. Immunol. 15, 241-249. doi: 10.1093/intimm/dxg022.
-
(2003)
Int. Immunol
, vol.15
, pp. 241-249
-
-
Cwiklinska, H.1
Mycko, M.P.2
Luvsannorov, O.3
Walkowiak, B.4
Brosnan, C.F.5
Raine, C.S.6
-
23
-
-
70449382894
-
Myelin under stress
-
D'Antonio, M., Feltri, M. L., and Wrabetz, L. (2009). Myelin under stress. J. Neurosci. Res. 87, 3241-3249. doi: 10.1002/jnr.22066.
-
(2009)
J. Neurosci. Res
, vol.87
, pp. 3241-3249
-
-
D'Antonio, M.1
Feltri, M.L.2
Wrabetz, L.3
-
24
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
-
Deng, J., Lu, P. D., Zhang, Y., Scheuner, D., Kaufman, R. J., Sonenberg, N., et al. (2004). Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol. Cell. Biol. 24, 10161-10168. doi: 10.1128/MCB.24.23.10161-10168.2004.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 10161-10168
-
-
Deng, J.1
Lu, P.D.2
Zhang, Y.3
Scheuner, D.4
Kaufman, R.J.5
Sonenberg, N.6
-
25
-
-
78650573911
-
The relevance of animal models in multiple sclerosis research
-
Denic, A., Johnson, A. J., Bieber, A. J., Warrington, A. E., Rodriguez, M., and Pirko, I. (2011). The relevance of animal models in multiple sclerosis research. Pathophysiology 18, 21-29. doi: 10.1016/j.pathophys.2010.04.004.
-
(2011)
Pathophysiology
, vol.18
, pp. 21-29
-
-
Denic, A.1
Johnson, A.J.2
Bieber, A.J.3
Warrington, A.E.4
Rodriguez, M.5
Pirko, I.6
-
26
-
-
80555133285
-
Neuroinflammation and endoplasmic reticulum stress are coregulated by crocin to prevent demyelination and neurodegeneration
-
Deslauriers, A. M., Afkhami-Goli, A., Paul, A. M., Bhat, R. K., Acharjee, S., Ellestad, K. K., et al. (2011). Neuroinflammation and endoplasmic reticulum stress are coregulated by crocin to prevent demyelination and neurodegeneration. J. Immunol. 187, 4788-4799. doi: 10.4049/jimmunol.1004111.
-
(2011)
J. Immunol
, vol.187
, pp. 4788-4799
-
-
Deslauriers, A.M.1
Afkhami-Goli, A.2
Paul, A.M.3
Bhat, R.K.4
Acharjee, S.5
Ellestad, K.K.6
-
27
-
-
80053252011
-
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
-
Doyle, K. M., Kennedy, D., Gorman, A. M., Gupta, S., Healy, S. J., and Samali, A. (2011). Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders. J. Cell. Mol. Med. 15, 2025-2039. doi: 10.1111/j.1582-4934.2011.01374.x.
-
(2011)
J. Cell. Mol. Med
, vol.15
, pp. 2025-2039
-
-
Doyle, K.M.1
Kennedy, D.2
Gorman, A.M.3
Gupta, S.4
Healy, S.J.5
Samali, A.6
-
28
-
-
78549234073
-
Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis
-
Dutta, R., and Trapp, B. D. (2011). Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog. Neurobiol. 93, 1-12. doi: 10.1016/j.pneurobio.2010.09.005.
-
(2011)
Prog. Neurobiol
, vol.93
, pp. 1-12
-
-
Dutta, R.1
Trapp, B.D.2
-
29
-
-
79959909381
-
Myelin regeneration: a recapitulation of development?
-
Fancy, S. P., Chan, J. R., Baranzini, S. E., Franklin, R. J., and Rowitch, D. H. (2011). Myelin regeneration: a recapitulation of development? Annu. Rev. Neurosci. 34, 21-43. doi: 10.1146/annurev-neuro-061010-113629.
-
(2011)
Annu. Rev. Neurosci
, vol.34
, pp. 21-43
-
-
Fancy, S.P.1
Chan, J.R.2
Baranzini, S.E.3
Franklin, R.J.4
Rowitch, D.H.5
-
30
-
-
0029671318
-
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
-
Ferber, I. A., Brocke, S., Taylor-Edwards, C., Ridgway, W., Dinisco, C., Steinman, L., et al. (1996). Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J. Immunol. 156, 5-7.
-
(1996)
J. Immunol
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
Ridgway, W.4
Dinisco, C.5
Steinman, L.6
-
31
-
-
0036720034
-
Why does remyelination fail in multiple sclerosis?
-
Franklin, R. J. (2002). Why does remyelination fail in multiple sclerosis? Nat. Rev. Neurosci. 3, 705-714. doi: 10.1038/nrn917.
-
(2002)
Nat. Rev. Neurosci
, vol.3
, pp. 705-714
-
-
Franklin, R.J.1
-
32
-
-
54249124952
-
Remyelination in the CNS: from biology to therapy
-
Franklin, R. J., and Ffrench-Constant, C. (2008). Remyelination in the CNS: from biology to therapy. Nat. Rev. Neurosci. 9, 839-855. doi: 10.1038/nrn2480.
-
(2008)
Nat. Rev. Neurosci
, vol.9
, pp. 839-855
-
-
Franklin, R.J.1
Ffrench-Constant, C.2
-
33
-
-
33644607018
-
Multiple sclerosis-the plaque and its pathogenesis
-
Frohman, E. M., Racke, M. K., and Raine, C. S. (2006). Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 354, 942-955. doi: 10.1056/NEJMra052130.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 942-955
-
-
Frohman, E.M.1
Racke, M.K.2
Raine, C.S.3
-
34
-
-
84862977176
-
An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy
-
Gade, P., Ramachandran, G., Maachani, U. B., Rizzo, M. A., Okada, T., Prywes, R., et al. (2012). An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy. Proc. Natl. Acad. Sci. U.S.A. 109, 10316-10321. doi: 10.1073/pnas.1119273109.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 10316-10321
-
-
Gade, P.1
Ramachandran, G.2
Maachani, U.B.3
Rizzo, M.A.4
Okada, T.5
Prywes, R.6
-
35
-
-
35548935675
-
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells
-
Gass, J. N., Jiang, H. Y., Wek, R. C., and Brewer, J. W. (2008). The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells. Mol. Immunol. 45, 1035-1043. doi: 10.1016/j.molimm.2007.07.029.
-
(2008)
Mol. Immunol
, vol.45
, pp. 1035-1043
-
-
Gass, J.N.1
Jiang, H.Y.2
Wek, R.C.3
Brewer, J.W.4
-
36
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass, C. K., Saijo, K., Winner, B., Marchetto, M. C., and Gage, F. H. (2010). Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934. doi: 10.1016/j.cell.2010.02.016.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
37
-
-
84899925732
-
Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart
-
Glembotski, C. C. (2014). Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart. J. Mol. Cell Cardiol. 71, 11-15. doi: 10.1016/j.yjmcc.2013.09.018.
-
(2014)
J. Mol. Cell Cardiol
, vol.71
, pp. 11-15
-
-
Glembotski, C.C.1
-
38
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold, R., Linington, C., and Lassmann, H. (2006). Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129, 1953-1971. doi: 10.1093/brain/awl075.
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
39
-
-
67349216357
-
Autoimmune T cell responses in the central nervous system
-
Goverman, J. (2009). Autoimmune T cell responses in the central nervous system. Nat. Rev. Immunol. 9, 393-407. doi: 10.1038/nri2550.
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 393-407
-
-
Goverman, J.1
-
40
-
-
70450214826
-
CHOP and the endoplasmic reticulum stress response in myelinating glia
-
Gow, A., and Wrabetz, L. (2009). CHOP and the endoplasmic reticulum stress response in myelinating glia. Curr. Opin. Neurobiol. 19, 505-510. doi: 10.1016/j.conb.2009.08.007.
-
(2009)
Curr. Opin. Neurobiol
, vol.19
, pp. 505-510
-
-
Gow, A.1
Wrabetz, L.2
-
41
-
-
0036437307
-
Transcriptional and translational control in the mammalian unfolded protein response
-
Harding, H. P., Calfon, M., Urano, F., Novoa, I., and Ron, D. (2002). Transcriptional and translational control in the mammalian unfolded protein response. Annu. Rev. Cell. Dev. Biol. 18, 575-599. doi: 10.1146/annurev.cellbio.18.011402.160624.
-
(2002)
Annu. Rev. Cell. Dev. Biol
, vol.18
, pp. 575-599
-
-
Harding, H.P.1
Calfon, M.2
Urano, F.3
Novoa, I.4
Ron, D.5
-
42
-
-
0035787914
-
Translational regulation in the cellular response to biosynthetic load on the endoplasmic reticulum
-
Harding, H. P., Novoa, I., Bertolotti, A., Zeng, H., Zhang, Y., Urano, F., et al. (2001). Translational regulation in the cellular response to biosynthetic load on the endoplasmic reticulum. Cold Spring Harb. Symp. Quant. Biol. 66, 499-508. doi: 10.1101/sqb.2001.66.499.
-
(2001)
Cold Spring Harb. Symp. Quant. Biol
, vol.66
, pp. 499-508
-
-
Harding, H.P.1
Novoa, I.2
Bertolotti, A.3
Zeng, H.4
Zhang, Y.5
Urano, F.6
-
43
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding, H. P., Zhang, Y., and Ron, D. (1999). Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397, 271-274. doi: 10.1038/16729.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
44
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding, H. P., Zhang, Y., Zeng, H., Novoa, I., Lu, P. D., Calfon, M., et al. (2003). An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell. 11, 619-633. doi: 10.1016/S1097-2765(03)00105-9.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
-
45
-
-
84871759394
-
Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK
-
Harding, H. P., Zyryanova, A. F., and Ron, D. (2012). Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK. J. Biol. Chem. 287, 44338-44344. doi: 10.1074/jbc.M112.428987.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 44338-44344
-
-
Harding, H.P.1
Zyryanova, A.F.2
Ron, D.3
-
46
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
Hetz, C. (2012). The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell. Biol. 13, 89-102. doi: 10.1038/nrm3270.
-
(2012)
Nat. Rev. Mol. Cell. Biol
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
47
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz, C., Chevet, E., and Harding, H. P. (2013). Targeting the unfolded protein response in disease. Nat. Rev. Drug Discov. 12, 703-719. doi: 10.1038/nrd3976.
-
(2013)
Nat. Rev. Drug Discov
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
48
-
-
84897094564
-
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
-
Hetz, C., and Mollereau, B. (2014). Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat. Rev. Neurosci. 15, 233-249. doi: 10.1038/nrn3689.
-
(2014)
Nat. Rev. Neurosci
, vol.15
, pp. 233-249
-
-
Hetz, C.1
Mollereau, B.2
-
49
-
-
0034142394
-
Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination
-
Hisahara, S., Araki, T., Sugiyama, F., Yagami, K., Suzuki, M., Abe, K., et al. (2000). Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination. EMBO J. 19, 341-348. doi: 10.1093/emboj/19.3.341.
-
(2000)
EMBO J
, vol.19
, pp. 341-348
-
-
Hisahara, S.1
Araki, T.2
Sugiyama, F.3
Yagami, K.4
Suzuki, M.5
Abe, K.6
-
50
-
-
0037491616
-
Caspase-mediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination
-
Hisahara, S., Okano, H., and Miura, M. (2003). Caspase-mediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination. Neurosci. Res. 46, 387-397. doi: 10.1016/S0168-0102(03)00127-5.
-
(2003)
Neurosci. Res
, vol.46
, pp. 387-397
-
-
Hisahara, S.1
Okano, H.2
Miura, M.3
-
51
-
-
27144460509
-
Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis
-
Hövelmeyer, N., Hao, Z., Kranidioti, K., Kassiotis, G., Buch, T., Frommer, F., et al. (2005). Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis. J. Immunol. 175, 5875-5884. doi: 10.4049/jimmunol.175.9.5875.
-
(2005)
J. Immunol
, vol.175
, pp. 5875-5884
-
-
Hövelmeyer, N.1
Hao, Z.2
Kranidioti, K.3
Kassiotis, G.4
Buch, T.5
Frommer, F.6
-
52
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu, P., Han, Z., Couvillon, A. D., Kaufman, R. J., and Exton, J. H. (2006). Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol. Cell. Biol. 26, 3071-3084. doi: 10.1128/MCB.26.8.3071-3084.2006.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
53
-
-
84896319455
-
Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination
-
Hussien, Y., Cavener, D. R., and Popko, B. (2014). Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination. Glia 62, 680-691. doi: 10.1002/glia.22634.
-
(2014)
Glia
, vol.62
, pp. 680-691
-
-
Hussien, Y.1
Cavener, D.R.2
Popko, B.3
-
54
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi, N. N., Lee, A. H., Vallabhajosyula, P., Otipoby, K. L., Rajewsky, K., and Glimcher, L. H. (2003). Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat. Immunol. 4, 321-329. doi: 10.1038/ni907.
-
(2003)
Nat. Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
55
-
-
0043133837
-
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses
-
Jiang, H. Y., Wek, S. A., McGrath, B. C., Scheuner, D., Kaufman, R. J., Cavener, D. R., et al. (2003). Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses. Mol. Cell. Biol. 23, 5651-5663. doi: 10.1128/MCB.23.16.5651-5663.2003.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5651-5663
-
-
Jiang, H.Y.1
Wek, S.A.2
McGrath, B.C.3
Scheuner, D.4
Kaufman, R.J.5
Cavener, D.R.6
-
56
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin, M., and Lin, A. (2002). NF-kappaB at the crossroads of life and death. Nat. Immunol. 3, 221-227. doi: 10.1038/ni0302-221.
-
(2002)
Nat. Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
57
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
-
Kaufman, R. J. (1999). Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13, 1211-1233. doi: 10.1101/gad.13.10.1211.
-
(1999)
Genes Dev
, vol.13
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
58
-
-
78751556358
-
Control of NF-κB and inflammation by the unfolded protein response
-
Kitamura, M. (2011). Control of NF-κB and inflammation by the unfolded protein response. Int. Rev. Immunol. 30, 4-15. doi: 10.3109/08830185.2010.522281.
-
(2011)
Int. Rev. Immunol
, vol.30
, pp. 4-15
-
-
Kitamura, M.1
-
59
-
-
0034487540
-
Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma
-
LaFerla, F. M., Sugarman, M. C., Lane, T. E., and Leissring, M. A. (2000). Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma. J. Mol. Neurosci. 15, 45-59. doi: 10.1385/JMN:15:1:45.
-
(2000)
J. Mol. Neurosci
, vol.15
, pp. 45-59
-
-
LaFerla, F.M.1
Sugarman, M.C.2
Lane, T.E.3
Leissring, M.A.4
-
60
-
-
77955656367
-
Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models
-
Lassmann, H. (2010). Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models. Exp. Neurol. 225, 2-8. doi: 10.1016/j.expneurol.2009.10.009.
-
(2010)
Exp. Neurol
, vol.225
, pp. 2-8
-
-
Lassmann, H.1
-
61
-
-
33846806080
-
A little stress is good: IFN-gamma, demyelination, and multiple sclerosis
-
Lees, J. R., and Cross, A. H. (2007). A little stress is good: IFN-gamma, demyelination, and multiple sclerosis. J. Clin. Invest. 117, 297-299. doi: 10.1172/JCI31254.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 297-299
-
-
Lees, J.R.1
Cross, A.H.2
-
62
-
-
84925147662
-
Impaired eIF2B activity in oligodendrocytes contributes to VWMD pathogenesis
-
Lin, W. (2015). Impaired eIF2B activity in oligodendrocytes contributes to VWMD pathogenesis. Neural. Regen. Res. 10, 195-197 doi: 10.4103/1673-5374.152366.
-
(2015)
Neural. Regen. Res
, vol.10
, pp. 195-197
-
-
Lin, W.1
-
63
-
-
33846811702
-
The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage
-
Lin, W., Bailey, S. L., Ho, H., Harding, H. P., Ron, D., Miller, S. D., et al. (2007). The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. J. Clin. Invest. 117, 448-456. doi: 10.1172/JCI29571.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 448-456
-
-
Lin, W.1
Bailey, S.L.2
Ho, H.3
Harding, H.P.4
Ron, D.5
Miller, S.D.6
-
64
-
-
22344435167
-
Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma
-
Lin, W., Harding, H. P., Ron, D., and Popko, B. (2005). Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. J. Cell. Biol. 169, 603-612. doi: 10.1083/jcb.200502086.
-
(2005)
J. Cell. Biol
, vol.169
, pp. 603-612
-
-
Lin, W.1
Harding, H.P.2
Ron, D.3
Popko, B.4
-
65
-
-
33646232737
-
Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress
-
Lin, W., Kemper, A., Dupree, J. L., Harding, H. P., Ron, D., and Popko, B. (2006). Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress. Brain 129, 1306-1318. doi: 10.1093/brain/awl044.
-
(2006)
Brain
, vol.129
, pp. 1306-1318
-
-
Lin, W.1
Kemper, A.2
Dupree, J.L.3
Harding, H.P.4
Ron, D.5
Popko, B.6
-
66
-
-
8544260349
-
Interferon-gamma induced medulloblastoma in the developing cerebellum
-
Lin, W., Kemper, A., McCarthy, K. D., Pytel, P., Wang, J. P., Campbell, I. L., et al. (2004). Interferon-gamma induced medulloblastoma in the developing cerebellum. J. Neurosci. 24, 10074-10083. doi: 10.1523/JNEUROSCI.2604-04.2004.
-
(2004)
J. Neurosci
, vol.24
, pp. 10074-10083
-
-
Lin, W.1
Kemper, A.2
McCarthy, K.D.3
Pytel, P.4
Wang, J.P.5
Campbell, I.L.6
-
67
-
-
55349142516
-
Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma
-
Lin, W., Kunkler, P. E., Harding, H. P., Ron, D., Kraig, R. P., and Popko, B. (2008). Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma. Am. J. Pathol. 173, 1508-1517. doi: 10.2353/ajpath.2008.080449.
-
(2008)
Am. J. Pathol
, vol.173
, pp. 1508-1517
-
-
Lin, W.1
Kunkler, P.E.2
Harding, H.P.3
Ron, D.4
Kraig, R.P.5
Popko, B.6
-
68
-
-
77955477978
-
Interferon-γ inhibits central nervous system myelination through both STAT1-dependent and STAT1-independent pathways
-
Lin, W., and Lin, Y. (2010). Interferon-γ inhibits central nervous system myelination through both STAT1-dependent and STAT1-independent pathways. J. Neurosci. Res. 88, 2569-2577. doi: 10.1002/jnr.22425.
-
(2010)
J. Neurosci. Res
, vol.88
, pp. 2569-2577
-
-
Lin, W.1
Lin, Y.2
-
69
-
-
84876001820
-
Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis
-
Lin, W., Lin, Y., Li, J., Fenstermaker, A. G., Way, S. W., Clayton, B., et al. (2013). Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. J. Neurosci. 33, 5980-5991. doi: 10.1523/JNEUROSCI.1636-12.2013.
-
(2013)
J. Neurosci
, vol.33
, pp. 5980-5991
-
-
Lin, W.1
Lin, Y.2
Li, J.3
Fenstermaker, A.G.4
Way, S.W.5
Clayton, B.6
-
70
-
-
63649109017
-
Endoplasmic reticulum stress in disorders of myelinating cells
-
Lin, W., and Popko, B. (2009). Endoplasmic reticulum stress in disorders of myelinating cells. Nat. Neurosci. 12, 379-385. doi: 10.1038/nn.2273.
-
(2009)
Nat. Neurosci
, vol.12
, pp. 379-385
-
-
Lin, W.1
Popko, B.2
-
71
-
-
84892179950
-
PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases
-
Lin, Y., Huang, G., Jamison, S., Li, J., Harding, H. P., Ron, D., et al. (2014a). PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. Am. J. Pathol. 184, 507-519. doi: 10.1016/j.ajpath.2013.10.009.
-
(2014)
Am. J. Pathol
, vol.184
, pp. 507-519
-
-
Lin, Y.1
Huang, G.2
Jamison, S.3
Li, J.4
Harding, H.P.5
Ron, D.6
-
72
-
-
84860523529
-
Interferon-γ activates nuclear factor-κ B in oligodendrocytes through a process mediated by the unfolded protein response
-
Lin, Y., Jamison, S., and Lin, W. (2012). Interferon-γ activates nuclear factor-κ B in oligodendrocytes through a process mediated by the unfolded protein response. PLoS ONE 7:e36408. doi: 10.1371/journal.pone.0036408.
-
(2012)
PLoS ONE
, vol.7
-
-
Lin, Y.1
Jamison, S.2
Lin, W.3
-
73
-
-
84906898010
-
Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice
-
Lin, Y., Pang, X., Huang, G., Jamison, S., Fang, J., Harding, H. P., et al. (2014b). Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. J. Neurosci. 34, 12182-12191. doi: 10.1523/JNEUROSCI.1373-14.2014.
-
(2014)
J. Neurosci
, vol.34
, pp. 12182-12191
-
-
Lin, Y.1
Pang, X.2
Huang, G.3
Jamison, S.4
Fang, J.5
Harding, H.P.6
-
74
-
-
0842285401
-
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2
-
Lu, P. D., Jousse, C., Marciniak, S. J., Zhang, Y., Novoa, I., Scheuner, D., et al. (2004). Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2. EMBO J. 23, 169-179. doi: 10.1038/sj.emboj.7600030.
-
(2004)
EMBO J
, vol.23
, pp. 169-179
-
-
Lu, P.D.1
Jousse, C.2
Marciniak, S.J.3
Zhang, Y.4
Novoa, I.5
Scheuner, D.6
-
75
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
Marciniak, S. J., and Ron, D. (2006). Endoplasmic reticulum stress signaling in disease. Physiol. Rev. 86, 1133-1149. doi: 10.1152/physrev.00015.2006.
-
(2006)
Physiol. Rev
, vol.86
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
76
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak, S. J., Yun, C. Y., Oyadomari, S., Novoa, I., Zhang, Y., Jungreis, R., et al. (2004). CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev. 18, 3066-3077. doi: 10.1101/gad.1250704.
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
-
77
-
-
0035198691
-
The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system
-
Matsushima, G. K., and Morell, P. (2001). The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol. 11, 107-116. doi: 10.1111/j.1750-3639.2001.tb00385.x.
-
(2001)
Brain Pathol
, vol.11
, pp. 107-116
-
-
Matsushima, G.K.1
Morell, P.2
-
78
-
-
84899937866
-
Getting RIDD of RNA: IRE1 in cell fate regulation
-
Maurel, M., Chevet, E., Tavernier, J., and Gerlo, S. (2014). Getting RIDD of RNA: IRE1 in cell fate regulation. Trends Biochem. Sci. 39, 245-554. doi: 10.1016/j.tibs.2014.02.008.
-
(2014)
Trends Biochem. Sci
, vol.39
, pp. 245-554
-
-
Maurel, M.1
Chevet, E.2
Tavernier, J.3
Gerlo, S.4
-
79
-
-
84884753706
-
Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology
-
McGuire, C., Prinz, M., Beyaert, R., and van Loo, G. (2013). Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology. Trends Mol. Med. 19, 604-613. doi: 10.1016/j.molmed.2013.08.001.
-
(2013)
Trends Mol. Med
, vol.19
, pp. 604-613
-
-
McGuire, C.1
Prinz, M.2
Beyaert, R.3
van Loo, G.4
-
80
-
-
78650652403
-
Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination
-
McGuire, C., Volckaert, T., Wolke, U., Sze, M., de Rycke, R., Waisman, A., et al. (2010). Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination. J. Immunol. 185, 7646-7653. doi: 10.4049/jimmunol.1000930.
-
(2010)
J. Immunol
, vol.185
, pp. 7646-7653
-
-
McGuire, C.1
Volckaert, T.2
Wolke, U.3
Sze, M.4
de Rycke, R.5
Waisman, A.6
-
81
-
-
84867007198
-
Increased expression of ER stress-and hypoxia-associated molecules in grey matter lesions in multiple sclerosis
-
McMahon, J. M., McQuaid, S., Reynolds, R., and Fitz Gerald, U. F. (2012). Increased expression of ER stress-and hypoxia-associated molecules in grey matter lesions in multiple sclerosis. Mult. Scler. 18, 1437-1447. doi: 10.1177/1352458512438455.
-
(2012)
Mult. Scler
, vol.18
, pp. 1437-1447
-
-
McMahon, J.M.1
McQuaid, S.2
Reynolds, R.3
Fitz Gerald, U.F.4
-
82
-
-
84907157987
-
PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation
-
Meares, G. P., Liu, Y., Rajbhandari, R., Qin, H., Nozell, S. E., Mobley, J. A., et al. (2014). PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. Mol. Cell Biol. 34, 3911-3925. doi: 10.1128/MCB.00980-14.
-
(2014)
Mol. Cell Biol
, vol.34
, pp. 3911-3925
-
-
Meares, G.P.1
Liu, Y.2
Rajbhandari, R.3
Qin, H.4
Nozell, S.E.5
Mobley, J.A.6
-
83
-
-
0026601932
-
Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice
-
Merrill, J. E., Kono, D. H., Clayton, J., Ando, D. G., Hinton, D. R., and Hofman, F. M. (1992). Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proc. Natl. Aacd. Sci. U.S.A. 89, 574-578. doi: 10.1073/pnas.89.2.574.
-
(1992)
Proc. Natl. Aacd. Sci. U.S.A
, vol.89
, pp. 574-578
-
-
Merrill, J.E.1
Kono, D.H.2
Clayton, J.3
Ando, D.G.4
Hinton, D.R.5
Hofman, F.M.6
-
84
-
-
41649097176
-
Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions
-
Mháille, A. N., McQuaid, S., Windebank, A., Cunnea, P., McMahon, J., Samali, A., et al. (2008). Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions. J. Neuropathol. Exp. Neurol. 67, 200-211. doi: 10.1097/NEN.0b013e318165b239.
-
(2008)
J. Neuropathol. Exp. Neurol
, vol.67
, pp. 200-211
-
-
Mháille, A.N.1
McQuaid, S.2
Windebank, A.3
Cunnea, P.4
McMahon, J.5
Samali, A.6
-
85
-
-
84877824588
-
NF-κB signaling pathways: role in nervous system physiology and pathology
-
Mincheva-Tasheva, S., and Soler, R. M. (2013). NF-κB signaling pathways: role in nervous system physiology and pathology. Neuroscientist 19, 175-194. doi: 10.1177/1073858412444007.
-
(2013)
Neuroscientist
, vol.19
, pp. 175-194
-
-
Mincheva-Tasheva, S.1
Soler, R.M.2
-
86
-
-
0027102387
-
T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins
-
Mor, F., and Cohen, I. R. (1992). T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins. J. Clin. Invest. 90, 2447-2455. doi: 10.1172/JCI116136.
-
(1992)
J. Clin. Invest
, vol.90
, pp. 2447-2455
-
-
Mor, F.1
Cohen, I.R.2
-
87
-
-
84885463900
-
Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice
-
Moreno, J. A., Halliday, M., Molloy, C., Radford, H., Verity, N., Axten, J. M., et al. (2013). Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Sci. Transl. Med. 5, 206ra138. doi: 10.1126/scitranslmed.3006767.
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Moreno, J.A.1
Halliday, M.2
Molloy, C.3
Radford, H.4
Verity, N.5
Axten, J.M.6
-
88
-
-
1842782996
-
Anti-inflammatory properties of pro-inflammatory interferon-gamma
-
Mühl, H., and Pfeilschifter, J. (2003). Anti-inflammatory properties of pro-inflammatory interferon-gamma. Int. Immunopharmacol. 3, 1247-1255. doi: 10.1016/S1567-5769(03)00131-0.
-
(2003)
Int. Immunopharmacol
, vol.3
, pp. 1247-1255
-
-
Mühl, H.1
Pfeilschifter, J.2
-
89
-
-
2642539885
-
Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis
-
Mycko, M. P., Papoian, R., Boschert, U., Raine, C. S., and Selmaj, K. W. (2004). Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis. Clin. Neurol. Neurosurg. 106, 223-229. doi: 10.1016/j.clineuro.2004.02.019.
-
(2004)
Clin. Neurol. Neurosurg
, vol.106
, pp. 223-229
-
-
Mycko, M.P.1
Papoian, R.2
Boschert, U.3
Raine, C.S.4
Selmaj, K.W.5
-
90
-
-
84925267195
-
Myelination of the nervous system: mechanisms and functions
-
Nave, K. A., and Werner, H. B. (2014). Myelination of the nervous system: mechanisms and functions. Annu. Rev. Cell Dev. Biol. 30, 503-533. doi: 10.1146/annurev-cellbio-100913-013101.
-
(2014)
Annu. Rev. Cell Dev. Biol
, vol.30
, pp. 503-533
-
-
Nave, K.A.1
Werner, H.B.2
-
91
-
-
85005870165
-
Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination
-
Ní Fhlathartaigh, M., McMahon, J., Reynolds, R., Connolly, D., Higgins, E., Fitzgerald, U., et al. (2013). Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination. Acta Neuropathol. Commun. 1:37. doi: 10.1186/2051-5960-1-37.
-
(2013)
Acta Neuropathol. Commun
, vol.1
, pp. 37
-
-
Ní Fhlathartaigh, M.1
McMahon, J.2
Reynolds, R.3
Connolly, D.4
Higgins, E.5
Fitzgerald, U.6
-
92
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa, I., Zeng, H., Harding, H. P., and Ron, D. (2001). Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell. Biol. 153, 1011-1022. doi: 10.1083/jcb.153.5.1011.
-
(2001)
J. Cell. Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
93
-
-
84879368095
-
Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury
-
Ohri, S. S., Hetman, M., and Whittemore, S. R. (2013). Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury. Neurobiol. Dis. 58, 29-37. doi: 10.1016/j.nbd.2013.04.021.
-
(2013)
Neurobiol. Dis
, vol.58
, pp. 29-37
-
-
Ohri, S.S.1
Hetman, M.2
Whittemore, S.R.3
-
94
-
-
0023221133
-
Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system
-
Panitch, H. S., Hirsch, R. L., Schindler, J., and Johnson, K. P. (1987). Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 37, 1097-1102. doi: 10.1212/WNL.37.7.1097.
-
(1987)
Neurology
, vol.37
, pp. 1097-1102
-
-
Panitch, H.S.1
Hirsch, R.L.2
Schindler, J.3
Johnson, K.P.4
-
95
-
-
61649099869
-
Substantial archaeocortical atrophy and neuronal loss in multiple sclerosis
-
Papadopoulos, D., Dukes, S., Patel, R., Nicholas, R., Vora, A., and Reynolds, R. (2009). Substantial archaeocortical atrophy and neuronal loss in multiple sclerosis. Brain Pathol. 19, 238-253. doi: 10.1111/j.1750-3639.2008.00177.x.
-
(2009)
Brain Pathol
, vol.19
, pp. 238-253
-
-
Papadopoulos, D.1
Dukes, S.2
Patel, R.3
Nicholas, R.4
Vora, A.5
Reynolds, R.6
-
96
-
-
70450207226
-
Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease
-
Pavitt, G. D., and Proud, C. G. (2009). Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease. Biochem. Soc. Trans. 37, 1298-1310. doi: 10.1042/BST0371298.
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 1298-1310
-
-
Pavitt, G.D.1
Proud, C.G.2
-
97
-
-
0027193569
-
The oligodendrocyte and its many cellular processes
-
Pfeiffer, S. E., Warrington, A. E., and Bansal, R. (1993). The oligodendrocyte and its many cellular processes. Trends Cell. Biol. 3, 191-197. doi: 10.1016/0962-8924(93)90213-K.
-
(1993)
Trends Cell. Biol
, vol.3
, pp. 191-197
-
-
Pfeiffer, S.E.1
Warrington, A.E.2
Bansal, R.3
-
98
-
-
84856884830
-
Pathology of demyelinating diseases
-
Popescu, B. F., and Lucchinetti, C. F. (2012). Pathology of demyelinating diseases. Annu. Rev. Pathol. 7, 185-217. doi: 10.1146/annurev-pathol-011811-132443.
-
(2012)
Annu. Rev. Pathol
, vol.7
, pp. 185-217
-
-
Popescu, B.F.1
Lucchinetti, C.F.2
-
99
-
-
0032904541
-
Oligodendroglial response to the immune cytokine interferon gamma
-
Popko, B., and Baerwald, K. D. (1999). Oligodendroglial response to the immune cytokine interferon gamma. Neurochem. Res. 24, 331-338. doi: 10.1023/A:1022586726510.
-
(1999)
Neurochem. Res
, vol.24
, pp. 331-338
-
-
Popko, B.1
Baerwald, K.D.2
-
100
-
-
0031063399
-
The effects of interferon-gamma on the central nervous system
-
Popko, B., Corbin, J. G., Baerwald, K. D., Dupree, J., and Garcia, A. M. (1997). The effects of interferon-gamma on the central nervous system. Mol. Neurobiol. 14, 19-35. doi: 10.1007/BF02740619.
-
(1997)
Mol. Neurobiol
, vol.14
, pp. 19-35
-
-
Popko, B.1
Corbin, J.G.2
Baerwald, K.D.3
Dupree, J.4
Garcia, A.M.5
-
101
-
-
84864434405
-
Oligodendrocytes and the early multiple sclerosis lesion
-
Prineas, J. W., and Parratt, J. D. (2012). Oligodendrocytes and the early multiple sclerosis lesion. Ann. Neurol. 72, 18-31. doi: 10.1002/ana.23634.
-
(2012)
Ann. Neurol
, vol.72
, pp. 18-31
-
-
Prineas, J.W.1
Parratt, J.D.2
-
102
-
-
79251504265
-
Detecting and quantitating physiological endoplasmic reticulum stress
-
Qi, L., Yang, L., and Chen, H. (2011). Detecting and quantitating physiological endoplasmic reticulum stress. Methods Enzymol. 490, 137-146. doi: 10.1016/B978-0-12-385114-7.00008-8.
-
(2011)
Methods Enzymol
, vol.490
, pp. 137-146
-
-
Qi, L.1
Yang, L.2
Chen, H.3
-
103
-
-
0036476551
-
Stat1-dependent and-independent pathways in IFN-gamma-dependent signaling
-
Ramana, C. V., Gil, M. P., Schreiber, R. D., and Stark, G. R. (2002). Stat1-dependent and-independent pathways in IFN-gamma-dependent signaling. Trends Immunol. 23, 96-101. doi: 10.1016/S1471-4906(01)02118-4.
-
(2002)
Trends Immunol
, vol.23
, pp. 96-101
-
-
Ramana, C.V.1
Gil, M.P.2
Schreiber, R.D.3
Stark, G.R.4
-
104
-
-
79958279017
-
Overexpression of the dominant-negative form of interferon regulatory factor 1 in oligodendrocytes protects against experimental autoimmune encephalomyelitis
-
Ren, Z., Wang, Y., Tao, D., Liebenson, D., Liggett, T., Goswami, R., et al. (2011). Overexpression of the dominant-negative form of interferon regulatory factor 1 in oligodendrocytes protects against experimental autoimmune encephalomyelitis. J. Neurosci. 31, 8329-8341. doi: 10.1523/JNEUROSCI.1028-11.2011.
-
(2011)
J. Neurosci
, vol.31
, pp. 8329-8341
-
-
Ren, Z.1
Wang, Y.2
Tao, D.3
Liebenson, D.4
Liggett, T.5
Goswami, R.6
-
105
-
-
33646042221
-
Defective translation initiation causes vanishing of cerebral white matter
-
Scheper, G. C., Proud, C. G., and van der Knaap, M. S. (2006). Defective translation initiation causes vanishing of cerebral white matter. Trends Mol. Med. 12, 159-166. doi: 10.1016/j.molmed.2006.02.006.
-
(2006)
Trends Mol. Med
, vol.12
, pp. 159-166
-
-
Scheper, G.C.1
Proud, C.G.2
van der Knaap, M.S.3
-
106
-
-
43249109174
-
Endoplasmic reticulum stress responses
-
Schröder, M. (2008). Endoplasmic reticulum stress responses. Cell Mol. Life Sci. 65, 862-894. doi: 10.1007/s00018-007-7383-5.
-
(2008)
Cell Mol. Life Sci
, vol.65
, pp. 862-894
-
-
Schröder, M.1
-
107
-
-
0036069980
-
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
-
Shen, J., Chen, X., Hendershot, L., and Prywes, R. (2002). ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev. Cell 3, 99-111. doi: 10.1016/S1534-5807(02)00203-4.
-
(2002)
Dev. Cell
, vol.3
, pp. 99-111
-
-
Shen, J.1
Chen, X.2
Hendershot, L.3
Prywes, R.4
-
108
-
-
77950862182
-
Multiple sclerosis-candidate mechanisms underlying CNS atrophy
-
Siffrin, V., Vogt, J., Radbruch, H., Nitsch, R., and Zipp, F. (2010). Multiple sclerosis-candidate mechanisms underlying CNS atrophy. Trends Neurosci. 33, 202-210. doi: 10.1016/j.tins.2010.01.002.
-
(2010)
Trends Neurosci
, vol.33
, pp. 202-210
-
-
Siffrin, V.1
Vogt, J.2
Radbruch, H.3
Nitsch, R.4
Zipp, F.5
-
109
-
-
0037079142
-
The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease
-
Southwood, C. M., Garbern, J., Jiang, W., and Gow, A. (2002). The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease. Neuron 36, 585-596. doi: 10.1016/S0896-6273(02)01045-0.
-
(2002)
Neuron
, vol.36
, pp. 585-596
-
-
Southwood, C.M.1
Garbern, J.2
Jiang, W.3
Gow, A.4
-
110
-
-
5444222234
-
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
-
Sriburi, R., Jackowski, S., Mori, K., and Brewer, J. W. (2004). XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J. Cell. Biol. 167, 35-41. doi: 10.1083/jcb.200406136.
-
(2004)
J. Cell. Biol
, vol.167
, pp. 35-41
-
-
Sriburi, R.1
Jackowski, S.2
Mori, K.3
Brewer, J.W.4
-
111
-
-
0033231305
-
Assessment of animal models for MS and demyelinating disease in the design of rational therapy
-
Steinman, L. (1999). Assessment of animal models for MS and demyelinating disease in the design of rational therapy. Neuron 24, 511-514. doi: 10.1016/S0896-6273(00)81107-1.
-
(1999)
Neuron
, vol.24
, pp. 511-514
-
-
Steinman, L.1
-
112
-
-
0041625961
-
Quantifying the early stages of remyelination following cuprizone-induced demyelination
-
Stidworthy, M. F., Genoud, S., Suter, U., Mantei, N., and Franklin, R. J. (2003). Quantifying the early stages of remyelination following cuprizone-induced demyelination. Brain Pathol. 13, 329-339. doi: 10.1111/j.1750-3639.2003.tb00032.x.
-
(2003)
Brain Pathol
, vol.13
, pp. 329-339
-
-
Stidworthy, M.F.1
Genoud, S.2
Suter, U.3
Mantei, N.4
Franklin, R.J.5
-
113
-
-
84855767695
-
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
-
Stockwell, S. R., Platt, G., Barrie, S. E., Zoumpoulidou, G., Te Poele, R. H., Aherne, G. W., et al. (2012). Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. PLoS ONE 7:e28568. doi: 10.1371/journal.pone.0028568.
-
(2012)
PLoS ONE
, vol.7
-
-
Stockwell, S.R.1
Platt, G.2
Barrie, S.E.3
Zoumpoulidou, G.4
Te Poele, R.H.5
Aherne, G.W.6
-
114
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas, I., and Ron, D. (2011). Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell. Biol. 13, 184-190. doi: 10.1038/ncb0311-184.
-
(2011)
Nat. Cell. Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
115
-
-
48249139449
-
Multiple sclerosis: an immune or neurodegenerative disorder?
-
Trapp, B. D., and Nave, K. A. (2008). Multiple sclerosis: an immune or neurodegenerative disorder? Annu. Rev. Neurosci. 31, 247-269. doi: 10.1146/annurev.neuro.30.051606.094313.
-
(2008)
Annu. Rev. Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
116
-
-
79953288480
-
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
-
Tsaytler, P., Harding, H. P., Ron, D., and Bertolotti, A. (2011). Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 332, 91-94. doi: 10.1126/science.1201396.
-
(2011)
Science
, vol.332
, pp. 91-94
-
-
Tsaytler, P.1
Harding, H.P.2
Ron, D.3
Bertolotti, A.4
-
117
-
-
84863916403
-
In vitro and in vivo models of multiple sclerosis
-
van der Star, B. J., Vogel, D. Y., Kipp, M., Puentes, F., Baker, D., and Amor, S. (2012). In vitro and in vivo models of multiple sclerosis. CNS Neurol. Disord. Drug Targets 11, 570-588. doi: 10.2174/187152712801661284.
-
(2012)
CNS Neurol. Disord. Drug Targets
, vol.11
, pp. 570-588
-
-
van der Star, B.J.1
Vogel, D.Y.2
Kipp, M.3
Puentes, F.4
Baker, D.5
Amor, S.6
-
118
-
-
84862731075
-
Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration
-
Vigeveno, R. M., Wiebenga, O. T., Wattjes, M. P., Geurts, J. J., and Barkhof, F. (2012). Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration. J. Magn. Reson. Imaging. 36, 1-19. doi: 10.1002/jmri.23578.
-
(2012)
J. Magn. Reson. Imaging
, vol.36
, pp. 1-19
-
-
Vigeveno, R.M.1
Wiebenga, O.T.2
Wattjes, M.P.3
Geurts, J.J.4
Barkhof, F.5
-
119
-
-
70350044493
-
Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
-
Vogt, J., Paul, F., Aktas, O., Müller-Wielsch, K., Dörr, J., Dörr, S., et al. (2009). Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann. Neurol. 66, 310-322. doi: 10.1002/ana.21719.
-
(2009)
Ann. Neurol
, vol.66
, pp. 310-322
-
-
Vogt, J.1
Paul, F.2
Aktas, O.3
Müller-Wielsch, K.4
Dörr, J.5
Dörr, S.6
-
120
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter, P., and Ron, D. (2011). The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086. doi: 10.1126/science.1209038.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
121
-
-
84908344184
-
Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis
-
Wang, L., Popko, B., Tixier, E., and Roos, R. P. (2014). Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis. Neurobiol. Dis. 71, 317-324. doi: 10.1016/j.nbd.2014.08.010.
-
(2014)
Neurobiol. Dis
, vol.71
, pp. 317-324
-
-
Wang, L.1
Popko, B.2
Tixier, E.3
Roos, R.P.4
-
122
-
-
84906712846
-
The impact of the endoplasmic reticulum protein-folding environment on cancer development
-
Wang, M., and Kaufman, R. J. (2014). The impact of the endoplasmic reticulum protein-folding environment on cancer development. Nat. Rev. Cancer 14, 581-597. doi: 10.1038/nrc3800.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 581-597
-
-
Wang, M.1
Kaufman, R.J.2
-
123
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
Wang, S., and Kaufman, R. J. (2012). The impact of the unfolded protein response on human disease. J. Cell. Biol. 197, 857-867. doi: 10.1083/jcb.201110131.
-
(2012)
J. Cell. Biol
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
124
-
-
84924891315
-
Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic
-
Way, S. W., Podojil, J. R., Clayton, B. L., Zaremba, A., Collins, T. L., Kunjamma, R. B., et al. (2015). Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nat. Commun. 6, 6532. doi: 10.1038/ncomms7532.
-
(2015)
Nat. Commun
, vol.6
, pp. 6532
-
-
Way, S.W.1
Podojil, J.R.2
Clayton, B.L.3
Zaremba, A.4
Collins, T.L.5
Kunjamma, R.B.6
-
125
-
-
79953043284
-
Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine
-
Wheatley, A. K., Kramski, M., Alexander, M. R., Toe, J. G., Center, R. J., and Purcell, D. F. (2011). Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine. PLoS ONE 6:e18225. doi: 10.1371/journal.pone.0018225.
-
(2011)
PLoS ONE
, vol.6
-
-
Wheatley, A.K.1
Kramski, M.2
Alexander, M.R.3
Toe, J.G.4
Center, R.J.5
Purcell, D.F.6
-
126
-
-
14744292802
-
The changing face of cytokines in the brain: perspectives from EAE
-
Wheeler, R. D., and Owens, T. (2005). The changing face of cytokines in the brain: perspectives from EAE. Curr. Pharm. Des. 11, 1031-1037. doi: 10.2174/1381612053381657.
-
(2005)
Curr. Pharm. Des
, vol.11
, pp. 1031-1037
-
-
Wheeler, R.D.1
Owens, T.2
-
127
-
-
0030587910
-
IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
Willenborg, D. O., Fordham, S., Bernard, C. C., Cowden, W. B., and Ramshaw, I. A. (1996). IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157, 3223-3227.
-
(1996)
J. Immunol
, vol.157
, pp. 3223-3227
-
-
Willenborg, D.O.1
Fordham, S.2
Bernard, C.C.3
Cowden, W.B.4
Ramshaw, I.A.5
-
128
-
-
0019781220
-
Ultrastructural changes accompanying the growth of isolated oligodendrocytes
-
Wollmann, R. L., Szuchet, S., Barlow, J., and Jerkovic, M. (1981). Ultrastructural changes accompanying the growth of isolated oligodendrocytes. J. Neurosci. Res. 6, 757-769. doi: 10.1002/jnr.490060610.
-
(1981)
J. Neurosci. Res
, vol.6
, pp. 757-769
-
-
Wollmann, R.L.1
Szuchet, S.2
Barlow, J.3
Jerkovic, M.4
-
129
-
-
73349141743
-
Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling
-
Woo, C. W., Cui, D., Arellano, J., Dorweiler, B., Harding, H., Fitzgerald, K. A., et al. (2009). Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling. Nat. Cell. Biol. 11, 1473-1480. doi: 10.1038/ncb1996.
-
(2009)
Nat. Cell. Biol
, vol.11
, pp. 1473-1480
-
-
Woo, C.W.1
Cui, D.2
Arellano, J.3
Dorweiler, B.4
Harding, H.5
Fitzgerald, K.A.6
-
130
-
-
77956232915
-
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress
-
Yamamoto, K., Takahara, K., Oyadomari, S., Okada, T., Sato, T., Harada, A., et al. (2010). Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress. Mol. Biol. Cell. 21, 2975-2986. doi: 10.1091/mbc.E09-02-0133.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2975-2986
-
-
Yamamoto, K.1
Takahara, K.2
Oyadomari, S.3
Okada, T.4
Sato, T.5
Harada, A.6
-
131
-
-
70350011787
-
NF-kappa B, a potential therapeutic target for the treatment of multiple sclerosis
-
Yan, J., and Greer, J. M. (2008). NF-kappa B, a potential therapeutic target for the treatment of multiple sclerosis. CNS Neurol. Disord. Drug Targets 7, 536-557. doi: 10.2174/187152708787122941.
-
(2008)
CNS Neurol. Disord. Drug Targets
, vol.7
, pp. 536-557
-
-
Yan, J.1
Greer, J.M.2
-
132
-
-
47949099916
-
From endoplasmic-reticulum stress to the inflammatory response
-
Zhang, K., and Kaufman, R. J. (2008). From endoplasmic-reticulum stress to the inflammatory response. Nature 454, 455-462. doi: 10.1038/nature07203.
-
(2008)
Nature
, vol.454
, pp. 455-462
-
-
Zhang, K.1
Kaufman, R.J.2
|