Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice

Journal of Neuroscience

Volumn 34, Issue 36, 2014, Pages 12182-12191

  Lin, Yifeng ^a,b   Pang, Xiaosha ^a,b   Huang, Guangcun ^a,b   Jamison, Stephanie ^a,b   Fang, Jingye ^a,b   Harding, Heather P ^c   Ron, David ^c   Lin, Wensheng ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Eif2B mutations; Hypomyelination; Oligodendrocyte; Pancreatic endoplasmic reticulum kinase; Vanishing white matter disease

Indexed keywords

EIF2B MUTATIONS; HYPOMYELINATION; OLIGODENDROCYTE; PANCREATIC ENDOPLASMIC RETICULUM KINASE; VANISHING WHITE MATTER DISEASE;

ANIMALS; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2B; LEUKOENCEPHALOPATHIES; MICE; MYELIN SHEATH; OLIGODENDROGLIA; ORGAN SPECIFICITY;

EID: 84906898010     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1373-14.2014     Document Type: Article

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