Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

Translational Psychiatry

Volumn 4, Issue , 2014, Pages

  Zhubi, A ^a   Chen, Y ^a   Dong, E ^a   Cook, E H ^b   Guidotti, A ^a   Grayson, D R ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Autism; Cerebellum; Epigenetics; Gene expression; Postmortem

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; ANTIDEPRESSANT AGENT; DNA METHYLTRANSFERASE 1; GLUTAMATE DECARBOXYLASE 65; METHYL CPG BINDING PROTEIN 2; MOOD STABILIZER; NEUROLEPTIC AGENT; PROTEIN; REELIN; TET1 PROTEIN; UNCLASSIFIED DRUG; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; ONCOPROTEIN; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE; TET1 PROTEIN, HUMAN; DNA; GLUTAMATE DECARBOXYLASE 67;

ARTICLE; AUTISM; BRAIN REGION; CEREBELLUM CORTEX; CONTROLLED STUDY; EPIGENETICS; HUMAN; HUMAN TISSUE; HYDROXYMETHYL DNA IMMUNOPRECIPITATION; IMMUNOPRECIPITATION; METHYL DNA IMMUNOPRECIPITATION; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PYROSEQUENCING; TREATMENT DURATION; ANALOGS AND DERIVATIVES; GENETIC EPIGENESIS; GENETICS; HEALTH CARE FACILITY; METABOLISM; PATHOLOGY; BODY REGIONS; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; TRANSCRIPTION REGULATION;

CELL ADHESION MOLECULES, NEURONAL; CEREBELLAR CORTEX; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CYTOSINE; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; EXTRACELLULAR MATRIX PROTEINS; GLUTAMATE DECARBOXYLASE; HUMANS; METHYL-CPG-BINDING PROTEIN 2; NERVE TISSUE PROTEINS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; SERINE ENDOPEPTIDASES; TISSUE BANKS;

EID: 84892954147     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.123     Document Type: Article

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