Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons

Journal of Neuroscience

Volumn 23, Issue 7, 2003, Pages 2572-2581

  Chen, Wen G ^a   West, Anne E ^a   Tao, Xu ^a,d   Corfas, Gabriel ^a   Szentirmay, Marilyn N ^b   Sawadogo, Michèle ^b   Vinson, Charles ^c   Greenberg, Michael E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d CURIS INC   (United States)

Author keywords

Activity dependent neural development; Activity dependent transcription; BDNF; Brain derived neurotrophic factor; Calcium; Neural plasticity; Upstream stimulatory factor; USF1; USF2

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; CALCIUM RESPONSIVE E BOX ELEMENT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ACTIVITY DEPENDENT TRANSCRIPTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DNA LIBRARY; DNA PROTEIN COMPLEX; E BOX ELEMENT; EMBRYO; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MEMBRANE DEPOLARIZATION; MOLECULAR MECHANICS; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0345269738     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-07-02572.2003     Document Type: Article

References (69)

1. 467 is required for Smad2-Smad4 complex formation and signaling. J Biol Chem 272:27678-27685.
2. Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME (1995) N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience 64:653-664.
3. Benson DL, Huntsman MM, Jones EG (1994) Activity-dependent changes in GAD and preprotachykinin mRNAs in visual cortex of adult monkeys. Cereb Cortex 4:40-51.
4. Berger A, Cultaro CM, Segal S, Spiegel S (1998) The potent lipid mitogen sphingosylphosphocholine activates the DNA binding activity of upstream stimulating factor (USF), a basic helix-loop-helix zipper protein. Biochim Biophys Acta 1390:225-236.
5. 2+-dependent regulation in neuronal gene expression. Curr Opin Neurobiol 7:419-429.
6. Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358-1362.
7. Carthew RW, Chodosh LA, Sharp PA (1985) An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell 43:439-448.
8. Cheriyath V, Novina CD, Roy AL (1998) TFII-I regulates Vβ promoter activity through an initiator element. Mol Cell Biol 18:4444-4454.
9. Cheung E, Mayr P, Coda-Zabetta F, Woodman PG, Boam DS (1999) DNA-binding activity of the transcription factor upstream stimulatory factor-1 (USF-1) is regulated by cyclin-dependent phosphorylation. Biochem J 344[Pt 1]:145-152.
10. Chiang CM, Roeder RG (1995) Cloning of an intrinsic human TFIID sub-unit that interacts with multiple transcriptional activators. Science 267:531-536.
11. Clayton DF (1997) Role of gene regulation in song circuit development and song learning. J Neurobiol 33:549-571.
12. Corriveau PA, Huh GS, Shatz CJ (1998) Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron 21:505-520.
13. Cvekl A, Sax CM, Bresnick EH, Piatigorsky J (1994) A complex array of positive and negative elements regulates the chicken α A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins. Mol Cell Biol 14:7363-7376.
14. Dear TN, Hainzl T, Follo M, Nehls M, Wilmore H, Matena K, Boehm T (1997) Identification of interaction partners for the basic helix-loophelix protein E47. Oncogene 14:891-898.
15. Dolmetsch RE, Pajvani U, Fife K, Spotts JM, Greenberg ME (2001) Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science 294:333-339.
16. Durham PL, Sharma RV, Russo AF (1997) Repression of the calcitonin gene-related peptide promoter by 5-HT1 receptor activation. J Neurosci 17:9545-9553.
17. Ernfors P, Bengzon J, Kokaia Z, Persson H, Lindvall O (1991) Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis. Neuron 7:165-176.
18. Frenkel S, Kay G, Nechushtan H, Razin E (1998) Nuclear translocation of upstream stimulating factor 2 (USF2) in activated mast cells: a possible role in their survival. J Immunol 161:2881-2887.
19. Galibert MD, Boucontet L, Goding CR, Meo T (1997) Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor. J Immunol 159:6176-6183.
20. Galibert MD, Carreira S, Goding CR (2001) The USF-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression. EMBO J 20:5022-5031.
21. Ghosh A (1996) Cortical development: with an eye on neurotrophins. Curr Biol 6:130-133.
22. Ghosh A, Carnahan J, Greenberg ME (1994) Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263:1618-1623.
23. Gregor PD, Sawadogo M, Roeder RG (1990) The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev 4:1730-1740.
24. Howcroft TK, Murphy C, Weissman JD, Huber SJ, Sawadogo M, Singer DS (1999) Upstream stimulatory factor regulates major histocompatibility complex class I gene expression: the U2ΔE4 splice variant abrogates E-box activity. Mol Cell Biol 19:4788-4797.
25. Huh GS, Boulanger LM, Du H, Riquelme PA, Brotz TM, Shatz CJ (2000) Functional requirement for class I MHC in CNS development and plasticity. Science 290:2155-2159.
26. Impey S, Goodman RH (2001) CREB signaling - timing is everything. Sci STKE 2001:E1.
27. Katz LC, Shatz CJ (1996) Synaptic activity and the construction of cortical circuits. Science 274:1133-1138.
28. Kingsley-Kallesen ML, Kelly D, Rizzino A (1999) Transcriptional regulation of the transforming growth factor-β2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein. J Biol Chem 274:34020-34028.
29. Koenig H, Lu C (1967) RNA and protein synthesis in relation to neural function. A study of the neurobiological activity of actinomycin D in cat spinal cord. Trans Am Neurol Assoc 92:250-252.
30. Kokubo T, Takada R, Yamashita S, Gong DW, Roeder RG, Horikoshi M, Nakatani Y (1993) Identification of TFIID components required for transcriptional activation by upstream stimulatory factor. J Biol Chem 268:17554-17558.
31. Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME (2002) CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron 34:221-233.
32. Liu J, Antaya M, Boerboom D, Lussier JG, Silversides DW, Sirois J (1999) The delayed activation of the prostaglandin G/H synthase-2 promoter in bovine granulosa cells is associated with down-regulation of truncated upstream stimulatory factor-2. J Biol Chem 274:35037-35045.
33. Luo X, Sawadogo M (1996a) Antiproliferative properties of the USF family of helix-loop-helix transcription factors. Proc Natl Acad Sci USA 93:1308-1313.
34. Luo X, Sawadogo M (1996b) Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol Cell Biol 16:1367-1375.
35. Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME (1999) Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science 286:785-790.
36. Marmillot P, Scovell W (1998) Enhancement of transcription factor, USF, binding to the adenovirus major late promoter: effect of dithiothreitol and high mobility group protein-1. Biochim Biophys Acta 1395:228-236.
37. Moncollin V, Miyamoto NG, Zheng XM, Egly JM (1986) Purification of a factor specific: for the upstream element of the adenovirus-2 major late promoter. EMBO J 5:2577-2584.
38. Nagavarapu U, Danthi S, Boyd RT (2001) Characterization of a rat neuronal nicotinic acetylcholine receptor α7 promoter. J Biol Chem 276:16749-16757.
39. Nguyen PV, Abel T, Kandel ER (1994) Requirement of a critical period of transcription for induction of a late phase of LTP. Science 265:1104-1107.
40. Pallas SL (2001) Intrinsic and extrinsic factors that shape neocortical specification. Trends Neurosci 24:417-423.
41. Parker D, Rivera M, Zor T, Henrion-Caude A, Radhakrishnan I, Kumar A, Shapiro LH, Wright PE, Montminy M, Brindle PK (1999) Role of secondary structure in discrimination between constitutive and inducible activators. Mol Cell Biol 19:5601-5607.
42. Paterson JM, Morrison CF, Mendelson SC, McAllister J, Quinn JP (1995) An upstream stimulatory factor (USF) binding motif is critical for rat preprotachykinin-A promoter activity in PC12 cells. Biochem J 310:401-406.
43. Patterson SL, Grover LM, Schwartzkroin PA, Bothwell M (1992) Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9:1081-1088.
44. Poo MM (2001) Neurotrophins as synaptic modulators. Nat Rev Neurosci 2:24-32.
45. Qyang Y, Luo X, Lu T, Ismail PM, Krylov D, Vinson C, Sawadogo M (1999) Cell type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation. Mol Cell Biol 19:1508-1517.
46. Reach M, Xu LX, Young CS (1991) Transcription from the adenovirus major late promoter uses redundant activating elements. EMBO J 10:3439-3446.
47. Roy AL, Meisterernst M, Pognonec P, Roeder RG (1991) Cooperative interaction of an initiator-binding transcription initiation factor and the helixloop-helix activator USF. Nature 354:245-248.
48. Roy AL, Du H, Gregor PD, Novina CD, Martinez E, Roeder RG (1997) Cloning of an Inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. EMBO J 16:7091-7104.
49. Sasaki M, Gonzalez-Zulueta M, Huang H, Herring WJ, Ahn S, Ginty DD, Dawson VL, Dawson TM (2000) Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism. Proc Natl Acad Sci USA 97:8617-8622.
50. Sawadogo M, Roeder RG (1985) Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 43:165-175.
51. Sawadogo M, Van Dyke MW, Gregor PD, Roeder RG (1988) Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem 263:11985-11993.
52. Shaywitz AJ, Greenberg ME (1999) CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68:821-861.
53. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252:1427-1430.
54. Shieh PB, Hu SC, Bobb K, Timmusk T, Ghosh A (1998) Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20:727-740.
55. Sirito M, Walker S, Lin Q, Kozlowski MT, Klein WH, Sawadogo M (1992) Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers. Gene Expr 2:231-240.
56. Sirito M, Lin Q, Maity T, Sawadogo M (1994) Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells. Nucleic Acids Res 22:427-433.
57. Sirito M, Lin Q, Deng JM, Behringer RR, Sawadogo M (1998) Overlapping roles and asymmetrical cross-regulation of the USF proteins in mice. Proc Natl Acad Sci USA 95:3758-3763.
58. Sur M, Leamey CA (2001) Development and plasticity of cortical areas and networks. Nat Rev Neurosci 2:251-262.
59. Tabuchi A, Sakaya H, Kisukeda T, Fushiki H, Tsuda M (2002) Involvement of an upstream stimulatory factor as well as cAMP-responsive elementbinding protein in the activation of brain-derived neurotrophic factor gene promoter I. J Biol Chem 277:35920-35931.
60. 2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 20:709-726.
61. Tao X, West AE, Chen WG, Corfas G, Greenberg ME (2002) A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron 33:383-395.
62. Timmusk T, Palm K, Metsis M, Reintam T, Paalme V, Saarma M, Persson H (1993) Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 10:475-489.
63. Tokuyama W, Okuno H, Hashimoto T, Xin Li Y, Miyashita Y (2000) BDNF upregulation during declarative memory formation in monkey inferior temporal cortex. Nat Neurosci 3:1134-1142.
64. Viollet B, Lefrancois-Martinez AM, Henrion A, Kahn A, Raymondjean M, Martinez A (1996) Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. J Biol Chem 271:1405-1415.
65. West AE, Chen WG, Dalva MB, Dolmetsch RE, Kornhauser JM, Shaywitz AJ, Takasu MA, Tao X, Greenberg ME (2001) Calcium regulation of neuronal gene expression. Proc Natl Acad Sci USA 98:11024-11031.
66. Workman JL, Roeder RG, Kingston RE (1990) An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. EMBO J 9:1299-1308.
67. Xia Z, Dudek H, Miranti CK, Greenberg ME (1996) Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 16:5425-5436.
68. Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, Worley PF (1993) Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11:371-386.
69. Zhou Y, Deneris E, Zigmond RE (2001) Nicotinic acetylcholine receptor subunit proteins α7 and β4 decrease in the superior cervical ganglion after axotomy. J Neurobiol 46:178-192.