-
1
-
-
34548138278
-
Epigenetics: A historical overview
-
17998809
-
Holliday R (2006) Epigenetics: a historical overview. Epigenetics 1(2):76-80
-
(2006)
Epigenetics
, vol.1
, Issue.2
, pp. 76-80
-
-
Holliday, R.1
-
3
-
-
0037074010
-
Signaling network model of chromatin
-
DOI 10.1016/S0092-8674(02)01196-0
-
Schreiber SL, Bernstein BE (2002) Signaling network model of chromatin. Cell 111(6):771-778 (Pubitemid 36106399)
-
(2002)
Cell
, vol.111
, Issue.6
, pp. 771-778
-
-
Schreiber, S.L.1
Bernstein, B.E.2
-
4
-
-
69349098474
-
Epigenetics: Definition, mechanisms and clinical perspective
-
10.1055/s-0029-1237423 1:CAS:528:DC%2BD1MXhtFOis7zM 2791696 19711245
-
Dupont C, Armant DR, Brenner CA (2009) Epigenetics: definition, mechanisms and clinical perspective. Semin Reprod Med 27(5):351-357. doi: 10.1055/s-0029-1237423
-
(2009)
Semin Reprod Med
, vol.27
, Issue.5
, pp. 351-357
-
-
Dupont, C.1
Armant, D.R.2
Brenner, C.A.3
-
5
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
DOI 10.1038/ng1089
-
Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33(Suppl):245-254. doi: 10.1038/ng1089 (Pubitemid 36278835)
-
(2003)
Nature Genetics
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
6
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3(6):415-428. doi: 10.1038/nrg816 (Pubitemid 34587077)
-
(2002)
Nature Reviews Genetics
, vol.3
, Issue.6
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
7
-
-
77953995002
-
Covalent histone modifications - Miswritten, misinterpreted and mis-erased in human cancers
-
10.1038/nrc2876 1:CAS:528:DC%2BC3cXnvVShurc%3D 3262678 20574448
-
Chi P, Allis CD, Wang GG (2010) Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer 10(7):457-469. doi: 10.1038/nrc2876
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.7
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
8
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
DOI 10.1038/nature05918, PII NATURE05918
-
Reik W (2007) Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447(7143):425-432. doi: 10.1038/nature05918 (Pubitemid 46816749)
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 425-432
-
-
Reik, W.1
-
9
-
-
0014668932
-
DNA ticketing theory of memory
-
1:CAS:528:DyaF1MXkvFygtbc%3D 5799529
-
Griffith JS, Mahler HR (1969) DNA ticketing theory of memory. Nature 223(5206):580-582
-
(1969)
Nature
, vol.223
, Issue.5206
, pp. 580-582
-
-
Griffith, J.S.1
Mahler, H.R.2
-
10
-
-
43749098985
-
DNA methylation landscapes: Provocative insights from epigenomics
-
DOI 10.1038/nrg2341, PII NRG2341
-
Suzuki MM, Bird A (2008) DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 9(6):465-476. doi: 10.1038/nrg2341 (Pubitemid 351693975)
-
(2008)
Nature Reviews Genetics
, vol.9
, Issue.6
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
11
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
DOI 10.1038/nrg887
-
Li E (2002) Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3(9):662-673. doi: 10.1038/nrg887 (Pubitemid 34984255)
-
(2002)
Nature Reviews Genetics
, vol.3
, Issue.9
, pp. 662-673
-
-
Li, E.1
-
12
-
-
56149116270
-
DNA methylation in development and human disease
-
10.1016/j.mrfmmm.2008.08.006 1:CAS:528:DC%2BD1cXhtlyks7nJ 2647981 18778722
-
Gopalakrishnan S, Van Emburgh BO, Robertson KD (2008) DNA methylation in development and human disease. Mutat Res 647(1-2):30-38. doi: 10.1016/j.mrfmmm.2008.08.006
-
(2008)
Mutat Res
, vol.647
, Issue.1-2
, pp. 30-38
-
-
Gopalakrishnan, S.1
Van Emburgh, B.O.2
Robertson, K.D.3
-
13
-
-
84864700183
-
Epigenetic mechanisms in neurological disease
-
10.1038/nm.2828 1:CAS:528:DC%2BC38XhtFCrt7jI 3596876 22869198
-
Jakovcevski M, Akbarian S (2012) Epigenetic mechanisms in neurological disease. Nat Med 18(8):1194-1204. doi: 10.1038/nm.2828
-
(2012)
Nat Med
, vol.18
, Issue.8
, pp. 1194-1204
-
-
Jakovcevski, M.1
Akbarian, S.2
-
14
-
-
77958605856
-
Epigenetic choreographers of neurogenesis in the adult mammalian brain
-
10.1038/nn.2672 1:CAS:528:DC%2BC3cXhtlegs77N 3324277 20975758
-
Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H (2010) Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci 13(11):1338-1344. doi: 10.1038/nn.2672
-
(2010)
Nat Neurosci
, vol.13
, Issue.11
, pp. 1338-1344
-
-
Ma, D.K.1
Marchetto, M.C.2
Guo, J.U.3
Ming, G.L.4
Gage, F.H.5
Song, H.6
-
15
-
-
80053144962
-
A decade of exploring the cancer epigenome - Biological and translational implications
-
10.1038/nrc3130 1:CAS:528:DC%2BC3MXht1ajur7K 3307543 21941284
-
Baylin SB, Jones PA (2011) A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer 11(10):726-734. doi: 10.1038/nrc3130
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.10
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
16
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
DOI 10.1016/S0092-8674(00)81656-6
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3):247-257 (Pubitemid 29519904)
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
17
-
-
0033753779
-
The DNA methyltransferases of mammals
-
1:CAS:528:DC%2BD3cXnslGqs7k%3D 11005794
-
Bestor TH (2000) The DNA methyltransferases of mammals. Hum Mol Genet 9(16):2395-2402
-
(2000)
Hum Mol Genet
, vol.9
, Issue.16
, pp. 2395-2402
-
-
Bestor, T.H.1
-
18
-
-
70249141961
-
Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration
-
10.1016/j.ydbio.2009.07.017 1:CAS:528:DC%2BD1MXhtFamtrzE 2759669 19631206
-
Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halpern M, Stainier DY (2009) Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol 334(1):213-223. doi: 10.1016/j.ydbio.2009.07.017
-
(2009)
Dev Biol
, vol.334
, Issue.1
, pp. 213-223
-
-
Anderson, R.M.1
Bosch, J.A.2
Goll, M.G.3
Hesselson, D.4
Dong, P.D.5
Shin, D.6
Chi, N.C.7
Shin, C.H.8
Schlegel, A.9
Halpern, M.10
Stainier, D.Y.11
-
19
-
-
2442564700
-
Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
-
DOI 10.1101/gad.1176104
-
Sun LQ, Lee DW, Zhang Q, Xiao W, Raabe EH, Meeker A, Miao D, Huso DL, Arceci RJ (2004) Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes Dev 18(9):1035-1046. doi: 10.1101/gad.1176104 (Pubitemid 38620243)
-
(2004)
Genes and Development
, vol.18
, Issue.9
, pp. 1035-1046
-
-
Sun, L.-Q.1
Lee, D.W.2
Zhang, Q.3
Xiao, W.4
Raabe, E.H.5
Meeker, A.6
Miao, D.7
Huso, D.L.8
Arceci, R.J.9
-
20
-
-
0031792779
-
Identification and characterization of a family of mammalian methyl-CpG binding proteins
-
Hendrich B, Bird A (1998) Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol 18(11):6538-6547 (Pubitemid 28500543)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.11
, pp. 6538-6547
-
-
Hendrich, B.1
Bird, A.2
-
21
-
-
69249220176
-
DNA methylation and methyl-CpG binding proteins: Developmental requirements and function
-
10.1007/s00412-009-0221-9 1:CAS:528:DC%2BD1MXhtVarurfK 2729420 19506892
-
Bogdanovic O, Veenstra GJ (2009) DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 118(5):549-565. doi: 10.1007/s00412-009-0221-9
-
(2009)
Chromosoma
, vol.118
, Issue.5
, pp. 549-565
-
-
Bogdanovic, O.1
Veenstra, G.J.2
-
22
-
-
44949233068
-
Proteins that bind methylated DNA and human cancer: Reading the wrong words
-
DOI 10.1038/sj.bjc.6604374, PII 6604374
-
Lopez-Serra L, Esteller M (2008) Proteins that bind methylated DNA and human cancer: reading the wrong words. Br J Cancer 98(12):1881-1885. doi: 10.1038/sj.bjc.6604374 (Pubitemid 351821557)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.12
, pp. 1881-1885
-
-
Lopez-Serra, L.1
Esteller, M.2
-
23
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
DOI 10.1126/science.1153252
-
Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320(5880):1224-1229. doi: 10.1126/science.1153252 (Pubitemid 351929512)
-
(2008)
Science
, vol.320
, Issue.5880
, pp. 1224-1229
-
-
Chahrour, M.1
Sung, Y.J.2
Shaw, C.3
Zhou, X.4
Wong, S.T.C.5
Qin, J.6
Zoghbi, H.Y.7
-
24
-
-
80054047383
-
The role of MeCP2 in the brain
-
10.1146/annurev-cellbio-092910-154121 1:CAS:528:DC%2BC3MXhsFyqtbfF 21721946
-
Guy J, Cheval H, Selfridge J, Bird A (2011) The role of MeCP2 in the brain. Annu Rev Cell Dev Biol 27:631-652. doi: 10.1146/annurev-cellbio-092910- 154121
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 631-652
-
-
Guy, J.1
Cheval, H.2
Selfridge, J.3
Bird, A.4
-
25
-
-
0001129080
-
The bases of the nucleic acids of some bacterial and animal viruses: The occurrence of 5-hydroxymethylcytosine
-
1:CAS:528:DyaG2cXhvVyhtA%3D%3D 13115372
-
Wyatt GR, Cohen SS (1953) The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine. Biochem J 55(5):774-782
-
(1953)
Biochem J
, vol.55
, Issue.5
, pp. 774-782
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
26
-
-
0015298215
-
The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid
-
1:CAS:528:DyaE38XhtV2gsLY%3D 4538516
-
Penn NW, Suwalski R, O'Riley C, Bojanowski K, Yura R (1972) The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochem J 126(4):781-790
-
(1972)
Biochem J
, vol.126
, Issue.4
, pp. 781-790
-
-
Penn, N.W.1
Suwalski, R.2
O'Riley, C.3
Bojanowski, K.4
Yura, R.5
-
27
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
10.1126/science.1170116 1:CAS:528:DC%2BD1MXlslWnurY%3D 2715015 19372391
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929):930-935. doi: 10.1126/science.1170116
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
28
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
10.1038/nature09303 1:CAS:528:DC%2BC3cXovFCntro%3D 3491567 20639862
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466(7310):1129-1133. doi: 10.1038/nature09303
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
29
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
10.1126/science.1210944 1:CAS:528:DC%2BC3MXhtV2jt7nO 3462231 21817016
-
He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333(6047):1303-1307. doi: 10.1126/science.1210944
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
Sun, Y.11
Li, X.12
Dai, Q.13
Song, C.X.14
Zhang, K.15
He, C.16
Xu, G.L.17
-
30
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
10.1126/science.1210597 1:CAS:528:DC%2BC3MXhtV2jt7nN 3495246 21778364
-
Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333(6047):1300-1303. doi: 10.1126/science.1210597
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
31
-
-
84871563384
-
MeCP2 Binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
10.1016/j.cell.2012.11.022 1:CAS:528:DC%2BC38XhvVyls77I 3653293 23260135
-
Mellen M, Ayata P, Dewell S, Kriaucionis S, Heintz N (2012) MeCP2 Binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151(7):1417-1430. doi: 10.1016/j.cell.2012.11.022
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1417-1430
-
-
Mellen, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
32
-
-
82255192294
-
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
-
10.1038/nn.2959 1:CAS:528:DC%2BC3MXhtlyis7zP 3292193 22037496
-
Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, Jin P (2011) 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci 14(12):1607-1616. doi: 10.1038/nn.2959
-
(2011)
Nat Neurosci
, vol.14
, Issue.12
, pp. 1607-1616
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
Song, C.X.4
Wu, H.5
Dai, Q.6
Irier, H.7
Upadhyay, A.K.8
Gearing, M.9
Levey, A.I.10
Vasanthakumar, A.11
Godley, L.A.12
Chang, Q.13
Cheng, X.14
He, C.15
Jin, P.16
-
33
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
10.1038/nbt.1732 1:CAS:528:DC%2BC3cXhsFGgtr7L 3107705 21151123
-
Song CX, Szulwach KE, Fu Y, Dai Q, Yi C, Li X, Li Y, Chen CH, Zhang W, Jian X, Wang J, Zhang L, Looney TJ, Zhang B, Godley LA, Hicks LM, Lahn BT, Jin P, He C (2011) Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol 29(1):68-72. doi: 10.1038/nbt.1732
-
(2011)
Nat Biotechnol
, vol.29
, Issue.1
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
Dai, Q.4
Yi, C.5
Li, X.6
Li, Y.7
Chen, C.H.8
Zhang, W.9
Jian, X.10
Wang, J.11
Zhang, L.12
Looney, T.J.13
Zhang, B.14
Godley, L.A.15
Hicks, L.M.16
Lahn, B.T.17
Jin, P.18
He, C.19
-
34
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
10.1126/science.1169786 1:CAS:528:DC%2BD1MXlslWnurk%3D 3263819 19372393
-
Kriaucionis S, Heintz N (2009) The nuclear DNA base 5- hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324(5929):929-930. doi: 10.1126/science.1169786
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
35
-
-
77954842819
-
Quantification of the sixth DNA base hydroxymethylcytosine in the brain
-
10.1002/anie.201002033
-
Munzel M, Globisch D, Bruckl T, Wagner M, Welzmiller V, Michalakis S, Muller M, Biel M, Carell T (2010) Quantification of the sixth DNA base hydroxymethylcytosine in the brain. Angew Chem 49(31):5375-5377. doi: 10.1002/anie.201002033
-
(2010)
Angew Chem
, vol.49
, Issue.31
, pp. 5375-5377
-
-
Munzel, M.1
Globisch, D.2
Bruckl, T.3
Wagner, M.4
Welzmiller, V.5
Michalakis, S.6
Muller, M.7
Biel, M.8
Carell, T.9
-
36
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
10.1038/nature10102 1:CAS:528:DC%2BC3MXlvVahu7c%3D 3124347 21552279
-
Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, Agarwal S, Rao A (2011) Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473(7347):394-397. doi: 10.1038/nature10102
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
Tahiliani, M.11
Daley, G.Q.12
Liu, X.S.13
Ecker, J.R.14
Milos, P.M.15
Agarwal, S.16
Rao, A.17
-
37
-
-
79959859654
-
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells
-
10.1371/journal.pgen.1002154 1:CAS:528:DC%2BC3MXotF2nsbs%3D 3121778 21731508
-
Szulwach KE, Li X, Li Y, Song CX, Han JW, Kim S, Namburi S, Hermetz K, Kim JJ, Rudd MK, Yoon YS, Ren B, He C, Jin P (2011) Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet 7(6):e1002154. doi: 10.1371/journal.pgen.1002154
-
(2011)
PLoS Genet
, vol.7
, Issue.6
, pp. 1002154
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
Song, C.X.4
Han, J.W.5
Kim, S.6
Namburi, S.7
Hermetz, K.8
Kim, J.J.9
Rudd, M.K.10
Yoon, Y.S.11
Ren, B.12
He, C.13
Jin, P.14
-
38
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
10.1016/j.cell.2012.04.027 1:CAS:528:DC%2BC38Xntlylu7s%3D 3589129 22608086
-
Yu M, Hon GC, Szulwach KE, Song CX, Zhang L, Kim A, Li X, Dai Q, Shen Y, Park B, Min JH, Jin P, Ren B, He C (2012) Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 149(6):1368-1380. doi: 10.1016/j.cell.2012.04.027
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
Song, C.X.4
Zhang, L.5
Kim, A.6
Li, X.7
Dai, Q.8
Shen, Y.9
Park, B.10
Min, J.H.11
Jin, P.12
Ren, B.13
He, C.14
-
39
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
10.1038/nn.2514 1:CAS:528:DC%2BC3cXjtFynur8%3D 3060772 20228804
-
Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G (2010) Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13(4):423-430. doi: 10.1038/nn.2514
-
(2010)
Nat Neurosci
, vol.13
, Issue.4
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
Le, T.4
Li, E.5
Sweatt, J.D.6
Silva, A.J.7
Fan, G.8
-
40
-
-
33847614418
-
Covalent Modification of DNA Regulates Memory Formation
-
DOI 10.1016/j.neuron.2007.02.022, PII S0896627307001420
-
Miller CA, Sweatt JD (2007) Covalent modification of DNA regulates memory formation. Neuron 53(6):857-869. doi: 10.1016/j.neuron.2007.02.022 (Pubitemid 46367557)
-
(2007)
Neuron
, vol.53
, Issue.6
, pp. 857-869
-
-
Miller, C.A.1
Sweatt, J.D.2
-
41
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
DOI 10.1002/jnr.20404
-
Feng J, Chang H, Li E, Fan G (2005) Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res 79(6):734-746. doi: 10.1002/jnr.20404 (Pubitemid 40476498)
-
(2005)
Journal of Neuroscience Research
, vol.79
, Issue.6
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
42
-
-
0028267714
-
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
-
Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H (1994) Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56(1-2):39-44 (Pubitemid 24102005)
-
(1994)
Differentiation
, vol.56
, Issue.1-2
, pp. 39-44
-
-
Goto, K.1
Numata, M.2
Komura, J.-I.3
Ono, T.4
Bestor, T.H.5
Kondo, H.6
-
43
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
1:CAS:528:DyaK38XksVGgsr0%3D 1606615
-
Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69(6):915-926
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
44
-
-
34147186795
-
Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation
-
DOI 10.1017/S1472928807000222, PII S1472928807000222
-
Golshani P, Hutnick L, Schweizer F, Fan G (2005) Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus Relat Syst 3(3):227-233. doi: 10.1017/S1472928807000222 (Pubitemid 46566553)
-
(2005)
Thalamus and Related Systems
, vol.3
, Issue.3
, pp. 227-233
-
-
Golshani, P.1
Hutnick, L.2
Schweizer, F.3
Fan, G.4
-
45
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
DOI 10.1002/dvdy.21176
-
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R (2007) Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Dev Dyn 236(6):1663-1676. doi: 10.1002/dvdy.21176 (Pubitemid 46932369)
-
(2007)
Developmental Dynamics
, vol.236
, Issue.6
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
46
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
10.1126/science.1190485 1:CAS:528:DC%2BC3cXptVWgtrs%3D 3539760 20651149
-
Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, Sun YE (2010) Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 329(5990):444-448. doi: 10.1126/science.1190485
-
(2010)
Science
, vol.329
, Issue.5990
, pp. 444-448
-
-
Wu, H.1
Coskun, V.2
Tao, J.3
Xie, W.4
Ge, W.5
Yoshikawa, K.6
Li, E.7
Zhang, Y.8
Sun, Y.E.9
-
47
-
-
24344472335
-
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
-
DOI 10.1242/dev.01912
-
Fan G, Martinowich K, Chin MH, He F, Fouse SD, Hutnick L, Hattori D, Ge W, Shen Y, Wu H, ten Hoeve J, Shuai K, Sun YE (2005) DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132(15):3345-3356. doi: 10.1242/dev.01912 (Pubitemid 41246111)
-
(2005)
Development
, vol.132
, Issue.15
, pp. 3345-3356
-
-
Fan, G.1
Martinowich, K.2
Chin, M.H.3
He, F.4
Fouse, S.D.5
Hutnick, L.6
Hattori, D.7
Ge, W.8
Shen, Y.9
Wu, H.10
Ten Hoeve, J.11
Shuai, K.12
Sun, Y.E.13
-
48
-
-
33847065486
-
The Epigenomics of Cancer
-
DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
-
Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128(4):683-692. doi: 10.1016/j.cell.2007.01.029 (Pubitemid 46273572)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
49
-
-
40849139208
-
Molecular origins of cancer: Epigenetics in cancer
-
DOI 10.1056/NEJMra072067
-
Esteller M (2008) Epigenetics in cancer. N Engl J Med 358(11):1148-1159. doi: 10.1056/NEJMra072067 (Pubitemid 351398489)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.11
-
-
Esteller, M.1
-
50
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
DOI 10.1038/72785
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C (2000) Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24(2):132-138. doi: 10.1038/72785 (Pubitemid 30094712)
-
(2000)
Nature Genetics
, vol.24
, Issue.2
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.-J.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
51
-
-
22844457491
-
DNA methylation and human disease
-
DOI 10.1038/nrg1655
-
Robertson KD (2005) DNA methylation and human disease. Nat Rev Genet 6(8):597-610. doi: 10.1038/nrg1655 (Pubitemid 41044297)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.8
, pp. 597-610
-
-
Robertson, K.D.1
-
52
-
-
70449725209
-
Epigenetic mechanisms in neurological diseases: Genes, syndromes, and therapies
-
10.1016/S1474-4422(09)70262-5 1:CAS:528:DC%2BD1MXhsVertbbE 19833297
-
Urdinguio RG, Sanchez-Mut JV, Esteller M (2009) Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 8(11):1056-1072. doi: 10.1016/S1474-4422(09)70262-5
-
(2009)
Lancet Neurol
, vol.8
, Issue.11
, pp. 1056-1072
-
-
Urdinguio, R.G.1
Sanchez-Mut, J.V.2
Esteller, M.3
-
53
-
-
84878441665
-
Genomic insights into cancer-associated aberrant CpG island hypermethylation
-
10.1093/bfgp/els063 1:CAS:528:DC%2BC3sXos12hurg%3D 23341493
-
Sproul D, Meehan RR (2013) Genomic insights into cancer-associated aberrant CpG island hypermethylation. Brief Funct Genomics 12(3):174-190. doi: 10.1093/bfgp/els063
-
(2013)
Brief Funct Genomics
, vol.12
, Issue.3
, pp. 174-190
-
-
Sproul, D.1
Meehan, R.R.2
-
54
-
-
79957623760
-
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
-
10.1038/ng.830 1:CAS:528:DC%2BC3MXlsVGlurs%3D 3102765 21532572
-
Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, Simon M, Lander C, Boardman LA, Cunningham JM, Smith GE, Litchy WJ, Boes B, Atkinson EJ, Middha S, BD PJ, Parisi JE, Mer G, Smith DI, Dyck PJ (2011) Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet 43(6):595-600. doi: 10.1038/ng.830
-
(2011)
Nat Genet
, vol.43
, Issue.6
, pp. 595-600
-
-
Klein, C.J.1
Botuyan, M.V.2
Wu, Y.3
Ward, C.J.4
Nicholson, G.A.5
Hammans, S.6
Hojo, K.7
Yamanishi, H.8
Karpf, A.R.9
Wallace, D.C.10
Simon, M.11
Lander, C.12
Boardman, L.A.13
Cunningham, J.M.14
Smith, G.E.15
Litchy, W.J.16
Boes, B.17
Atkinson, E.J.18
Middha, S.19
Bd, P.J.20
Parisi, J.E.21
Mer, G.22
Smith, D.I.23
Dyck, P.J.24
more..
-
55
-
-
12144255958
-
Replication-independent chromatin loading of Dnmt1 during G2 and M phases
-
DOI 10.1038/sj.embor.7400295
-
Easwaran HP, Schermelleh L, Leonhardt H, Cardoso MC (2004) Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep 5(12):1181-1186. doi: 10.1038/sj.embor.7400295 (Pubitemid 40103614)
-
(2004)
EMBO Reports
, vol.5
, Issue.12
, pp. 1181-1186
-
-
Easwaran, H.P.1
Schermelleh, L.2
Leonhardt, H.3
Cardoso, M.C.4
-
56
-
-
84860491605
-
Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy
-
10.1093/hmg/dds035 1:CAS:528:DC%2BC38Xmt1Ggt7k%3D 22328086
-
Winkelmann J, Lin L, Schormair B, Kornum BR, Faraco J, Plazzi G, Melberg A, Cornelio F, Urban AE, Pizza F, Poli F, Grubert F, Wieland T, Graf E, Hallmayer J, Strom TM, Mignot E (2012) Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. Hum Mol Genet 21(10):2205-2210. doi: 10.1093/hmg/dds035
-
(2012)
Hum Mol Genet
, vol.21
, Issue.10
, pp. 2205-2210
-
-
Winkelmann, J.1
Lin, L.2
Schormair, B.3
Kornum, B.R.4
Faraco, J.5
Plazzi, G.6
Melberg, A.7
Cornelio, F.8
Urban, A.E.9
Pizza, F.10
Poli, F.11
Grubert, F.12
Wieland, T.13
Graf, E.14
Hallmayer, J.15
Strom, T.M.16
Mignot, E.17
-
57
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
-
10.1038/46052 1:CAS:528:DyaK1MXnsVektb8%3D 10647011
-
Xu GL, Bestor TH, Bourc'his D, Hsieh CL, Tommerup N, Bugge M, Hulten M, Qu X, Russo JJ, Viegas-Pequignot E (1999) Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402(6758):187-191. doi: 10.1038/46052
-
(1999)
Nature
, vol.402
, Issue.6758
, pp. 187-191
-
-
Xu, G.L.1
Bestor, T.H.2
Bourc'His, D.3
Hsieh, C.L.4
Tommerup, N.5
Bugge, M.6
Hulten, M.7
Qu, X.8
Russo, J.J.9
Viegas-Pequignot, E.10
-
58
-
-
0033435205
-
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
-
DOI 10.1073/pnas.96.25.14412
-
Hansen RS, Wijmenga C, Luo P, Stanek AM, Canfield TK, Weemaes CM, Gartler SM (1999) The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc Natl Acad Sci USA 96(25):14412-14417 (Pubitemid 30000664)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.25
, pp. 14412-14417
-
-
Hansen, R.S.1
Wijmenga, C.2
Luo, P.3
Stanek, A.M.4
Canfield, T.K.5
Weemaes, C.M.R.6
Gartler, S.M.7
-
59
-
-
39749152283
-
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function
-
DOI 10.1093/hmg/ddm341
-
Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD (2008) DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet 17(5):690-709. doi: 10.1093/hmg/ddm341 (Pubitemid 351292258)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.5
, pp. 690-709
-
-
Jin, B.1
Tao, Q.2
Peng, J.3
Soo, H.M.4
Wu, W.5
Ying, J.6
Fields, C.R.7
Delmas, A.I.8
Liu, X.9
Qiu, J.10
Robertson, K.D.11
-
60
-
-
79958846467
-
Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2
-
10.1016/j.ajhg.2011.04.018 3113345 21596365
-
de Greef JC, Wang J, Balog J, den Dunnen JT, Frants RR, Straasheijm KR, Aytekin C, van der Burg M, Duprez L, Ferster A, Gennery AR, Gimelli G, Reisli I, Schuetz C, Schulz A, Smeets DF, Sznajer Y, Wijmenga C, van Eggermond MC, Van Ostaijen-Ten Dam MM, Lankester AC, van Tol MJ, van den Elsen PJ, Weemaes CM, van der Maarel SM (2011) Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2. Am J Hum Genet 88(6):796-804. doi: 10.1016/j.ajhg.2011.04.018
-
(2011)
Am J Hum Genet
, vol.88
, Issue.6
, pp. 796-804
-
-
De Greef, J.C.1
Wang, J.2
Balog, J.3
Den Dunnen, J.T.4
Frants, R.R.5
Straasheijm, K.R.6
Aytekin, C.7
Van Der Burg, M.8
Duprez, L.9
Ferster, A.10
Gennery, A.R.11
Gimelli, G.12
Reisli, I.13
Schuetz, C.14
Schulz, A.15
Smeets, D.F.16
Sznajer, Y.17
Wijmenga, C.18
Van Eggermond, M.C.19
Van Ostaijen-Ten Dam, M.M.20
Lankester, A.C.21
Van Tol, M.J.22
Van Den Elsen, P.J.23
Weemaes, C.M.24
Van Der Maarel, S.M.25
more..
-
61
-
-
84867592763
-
A novel deletion in ZBTB24 in a Lebanese family with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2
-
10.1111/j.1399-0004.2011.01783.x 1:CAS:528:DC%2BC3sXjtFGj 21906047
-
Chouery E, Abou-Ghoch J, Corbani S, El Ali N, Korban R, Salem N, Castro C, Klayme S, Azoury-Abou Rjeily M, Khoury-Matar R, Debo G, Germanos-Haddad M, Delague V, Lefranc G, Megarbane A (2012) A novel deletion in ZBTB24 in a Lebanese family with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2. Clin Genet 82(5):489-493. doi: 10.1111/j.1399-0004. 2011.01783.x
-
(2012)
Clin Genet
, vol.82
, Issue.5
, pp. 489-493
-
-
Chouery, E.1
Abou-Ghoch, J.2
Corbani, S.3
El Ali, N.4
Korban, R.5
Salem, N.6
Castro, C.7
Klayme, S.8
Azoury-Abou Rjeily, M.9
Khoury-Matar, R.10
Debo, G.11
Germanos-Haddad, M.12
Delague, V.13
Lefranc, G.14
Megarbane, A.15
-
62
-
-
84862909358
-
DNMT3A mutations in acute myeloid leukemia: Stability during disease evolution and clinical implications
-
10.1182/blood-2011-07-369934 1:CAS:528:DC%2BC38XhsVKltL8%3D 22077061
-
Hou HA, Kuo YY, Liu CY, Chou WC, Lee MC, Chen CY, Lin LI, Tseng MH, Huang CF, Chiang YC, Lee FY, Liu MC, Liu CW, Tang JL, Yao M, Huang SY, Ko BS, Hsu SC, Wu SJ, Tsay W, Chen YC, Tien HF (2012) DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications. Blood 119(2):559-568. doi: 10.1182/blood-2011-07-369934
-
(2012)
Blood
, vol.119
, Issue.2
, pp. 559-568
-
-
Hou, H.A.1
Kuo, Y.Y.2
Liu, C.Y.3
Chou, W.C.4
Lee, M.C.5
Chen, C.Y.6
Lin, L.I.7
Tseng, M.H.8
Huang, C.F.9
Chiang, Y.C.10
Lee, F.Y.11
Liu, M.C.12
Liu, C.W.13
Tang, J.L.14
Yao, M.15
Huang, S.Y.16
Ko, B.S.17
Hsu, S.C.18
Wu, S.J.19
Tsay, W.20
Chen, Y.C.21
Tien, H.F.22
more..
-
63
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
10.1056/NEJMoa1005143 1:CAS:528:DC%2BC3cXhsF2ltb7K 3201818 21067377
-
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, Osborne JR, Lin L, O'Laughlin M, McMichael JF, Delehaunty KD, McGrath SD, Fulton LA, Magrini VJ, Vickery TL, Hundal J, Cook LL, Conyers JJ, Swift GW, Reed JP, Alldredge PA, Wylie T, Walker J, Kalicki J, Watson MA, Heath S, Shannon WD, Varghese N, Nagarajan R, Westervelt P, Tomasson MH, Link DC, Graubert TA, DiPersio JF, Mardis ER, Wilson RK (2010) DNMT3A mutations in acute myeloid leukemia. N Engl J Med 363(25):2424-2433. doi: 10.1056/NEJMoa1005143
-
(2010)
N Engl J Med
, vol.363
, Issue.25
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
McLellan, M.D.4
Lamprecht, T.5
Larson, D.E.6
Kandoth, C.7
Payton, J.E.8
Baty, J.9
Welch, J.10
Harris, C.C.11
Lichti, C.F.12
Townsend, R.R.13
Fulton, R.S.14
Dooling, D.J.15
Koboldt, D.C.16
Schmidt, H.17
Zhang, Q.18
Osborne, J.R.19
Lin, L.20
O'Laughlin, M.21
McMichael, J.F.22
Delehaunty, K.D.23
McGrath, S.D.24
Fulton, L.A.25
Magrini, V.J.26
Vickery, T.L.27
Hundal, J.28
Cook, L.L.29
Conyers, J.J.30
Swift, G.W.31
Reed, J.P.32
Alldredge, P.A.33
Wylie, T.34
Walker, J.35
Kalicki, J.36
Watson, M.A.37
Heath, S.38
Shannon, W.D.39
Varghese, N.40
Nagarajan, R.41
Westervelt, P.42
Tomasson, M.H.43
Link, D.C.44
Graubert, T.A.45
Dipersio, J.F.46
Mardis, E.R.47
Wilson, R.K.48
more..
-
64
-
-
0037636512
-
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
-
DOI 10.1073/pnas.1131928100
-
Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH (2003) Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci USA 100(11):6777-6782. doi: 10.1073/pnas.1131928100 (Pubitemid 36666656)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.11
, pp. 6777-6782
-
-
Zhao, X.1
Ueba, T.2
Christie, B.R.3
Barkho, B.4
McConnell, M.J.5
Nakashima, K.6
Lein, E.S.7
Eadie, B.D.8
Willhoite, A.R.9
Muotri, A.R.10
Summers, R.G.11
Chun, J.12
Lee, K.-F.13
Gage, F.H.14
-
65
-
-
55549108710
-
Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells
-
10.1074/jbc.M804899200 1:CAS:528:DC%2BD1cXhtF2hsLnO 18689796
-
Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X (2008) Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. J Biol Chem 283(41):27644-27652. doi: 10.1074/jbc.M804899200
-
(2008)
J Biol Chem
, vol.283
, Issue.41
, pp. 27644-27652
-
-
Li, X.1
Barkho, B.Z.2
Luo, Y.3
Smrt, R.D.4
Santistevan, N.J.5
Liu, C.6
Kuwabara, T.7
Gage, F.H.8
Zhao, X.9
-
66
-
-
0026747761
-
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
-
1:CAS:528:DyaK3sXitVOrtrg%3D 1606614
-
Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F, Bird A (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69(6):905-914
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 905-914
-
-
Lewis, J.D.1
Meehan, R.R.2
Henzel, W.J.3
Maurer-Fogy, I.4
Jeppesen, P.5
Klein, F.6
Bird, A.7
-
67
-
-
0037081840
-
Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation
-
Shahbazian MD, Antalffy B, Armstrong DL, Zoghbi HY (2002) Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet 11(2):115-124 (Pubitemid 34157003)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.2
, pp. 115-124
-
-
Shahbazian, M.D.1
Antalffy, B.2
Armstrong, D.L.3
Zoghbi, H.Y.4
-
68
-
-
35648978121
-
The Story of Rett Syndrome: From Clinic to Neurobiology
-
DOI 10.1016/j.neuron.2007.10.001, PII S0896627307007568
-
Chahrour M, Zoghbi HY (2007) The story of Rett syndrome: from clinic to neurobiology. Neuron 56(3):422-437. doi: 10.1016/j.neuron.2007.10.001 (Pubitemid 350026269)
-
(2007)
Neuron
, vol.56
, Issue.3
, pp. 422-437
-
-
Chahrour, M.1
Zoghbi, H.Y.2
-
69
-
-
76849094693
-
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
-
10.1016/j.molcel.2010.01.030 1:CAS:528:DC%2BC3cXlt1KkurY%3D 20188665
-
Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP (2010) Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol Cell 37(4):457-468. doi: 10.1016/j.molcel.2010.01.030
-
(2010)
Mol Cell
, vol.37
, Issue.4
, pp. 457-468
-
-
Skene, P.J.1
Illingworth, R.S.2
Webb, S.3
Kerr, A.R.4
James, K.D.5
Turner, D.J.6
Andrews, R.7
Bird, A.P.8
-
70
-
-
0025975985
-
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
-
Boyes J, Bird A (1991) DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 64(6):1123-1134 (Pubitemid 121001199)
-
(1991)
Cell
, vol.64
, Issue.6
, pp. 1123-1134
-
-
Boyes, J.1
Bird, A.2
-
71
-
-
0342437491
-
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
-
DOI 10.1016/S0092-8674(00)81887-5
-
Nan X, Campoy FJ, Bird A (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88(4):471-481 (Pubitemid 27154412)
-
(1997)
Cell
, vol.88
, Issue.4
, pp. 471-481
-
-
Xinsheng, N.1
Campoy, F.J.2
Bird, A.3
-
72
-
-
67249150482
-
Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus
-
10.1093/hmg/ddp181 1:CAS:528:DC%2BD1MXnt1eht7c%3D 19369296
-
Ben-Shachar S, Chahrour M, Thaller C, Shaw CA, Zoghbi HY (2009) Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus. Hum Mol Genet 18(13):2431-2442. doi: 10.1093/hmg/ddp181
-
(2009)
Hum Mol Genet
, vol.18
, Issue.13
, pp. 2431-2442
-
-
Ben-Shachar, S.1
Chahrour, M.2
Thaller, C.3
Shaw, C.A.4
Zoghbi, H.Y.5
-
73
-
-
11244328520
-
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
-
DOI 10.1038/ng1491
-
Horike S, Cai S, Miyano M, Cheng JF, Kohwi-Shigematsu T (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37(1):31-40. doi: 10.1038/ng1491 (Pubitemid 40070937)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 31-40
-
-
Horike, S.-I.1
Cai, S.2
Miyano, M.3
Cheng, J.-F.4
Kohwi-Shigematsu, T.5
-
74
-
-
29144447632
-
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2
-
DOI 10.1073/pnas.0507856102
-
Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY (2005) Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proc Natl Acad Sci USA 102(49):17551-17558. doi: 10.1073/pnas. 0507856102 (Pubitemid 41803535)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.49
, pp. 17551-17558
-
-
Young, J.I.1
Hong, E.P.2
Castle, J.C.3
Crespo-Barreto, J.4
Bowman, A.B.5
Rose, M.F.6
Kang, D.7
Richman, R.8
Johnson, J.M.9
Berget, S.10
Zoghbi, H.Y.11
-
75
-
-
0029347068
-
The X-linked methylated DNA binding protein, Mecp2, is subject to X inactivation in the mouse
-
1:CAS:528:DyaK2MXnvV2qsb8%3D 8589515
-
Adler DA, Quaderi NA, Brown SD, Chapman VM, Moore J, Tate P, Disteche CM (1995) The X-linked methylated DNA binding protein, Mecp2, is subject to X inactivation in the mouse. Mamm Genome 6(8):491-492
-
(1995)
Mamm Genome
, vol.6
, Issue.8
, pp. 491-492
-
-
Adler, D.A.1
Quaderi, N.A.2
Brown, S.D.3
Chapman, V.M.4
Moore, J.5
Tate, P.6
Disteche, C.M.7
-
76
-
-
47249103934
-
Severe congenital encephalopathy caused by MECP2 null mutations in males: Central hypoxia and reduced neuronal dendritic structure
-
DOI 10.1111/j.1399-0004.2008.01005.x
-
Schule B, Armstrong DD, Vogel H, Oviedo A, Francke U (2008) Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure. Clin Genet 74(2):116-126. doi: 10.1111/j.1399-0004.2008.01005.x (Pubitemid 351980383)
-
(2008)
Clinical Genetics
, vol.74
, Issue.2
, pp. 116-126
-
-
Schule, B.1
Armstrong, D.D.2
Vogel, H.3
Oviedo, A.4
Francke, U.5
-
77
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl- CpG-binding protein 2
-
DOI 10.1038/13810
-
Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23(2):185-188. doi: 10.1038/13810 (Pubitemid 29455390)
-
(1999)
Nature Genetics
, vol.23
, Issue.2
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
78
-
-
66149139048
-
Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome
-
10.1002/ana.21715 1:CAS:528:DC%2BC3cXhtlams7Y%3D 2801873 20035514
-
Ramocki MB, Peters SU, Tavyev YJ, Zhang F, Carvalho CM, Schaaf CP, Richman R, Fang P, Glaze DG, Lupski JR, Zoghbi HY (2009) Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome. Ann Neurol 66(6):771-782. doi: 10.1002/ana.21715
-
(2009)
Ann Neurol
, vol.66
, Issue.6
, pp. 771-782
-
-
Ramocki, M.B.1
Peters, S.U.2
Tavyev, Y.J.3
Zhang, F.4
Carvalho, C.M.5
Schaaf, C.P.6
Richman, R.7
Fang, P.8
Glaze, D.G.9
Lupski, J.R.10
Zoghbi, H.Y.11
-
79
-
-
33749590330
-
Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation
-
DOI 10.1016/j.neuron.2006.09.037, PII S0896627306007756
-
Zhou Z, Hong EJ, Cohen S, Zhao WN, Ho HY, Schmidt L, Chen WG, Lin Y, Savner E, Griffith EC, Hu L, Steen JA, Weitz CJ, Greenberg ME (2006) Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron 52(2):255-269. doi: 10.1016/j.neuron.2006.09.037 (Pubitemid 44548348)
-
(2006)
Neuron
, vol.52
, Issue.2
, pp. 255-269
-
-
Zhou, Z.1
Hong, E.J.2
Cohen, S.3
Zhao, W.-n.4
Ho, H.-y.H.5
Schmidt, L.6
Chen, W.G.7
Lin, Y.8
Savner, E.9
Griffith, E.C.10
Hu, L.11
Steen, J.A.J.12
Weitz, C.J.13
Greenberg, M.E.14
-
80
-
-
80053579176
-
Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function
-
10.1016/j.neuron.2011.08.022 1:CAS:528:DC%2BC3MXht12kt7bJ 3226708 21982370
-
Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME (2011) Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron 72(1):72-85. doi: 10.1016/j.neuron.2011.08.022
-
(2011)
Neuron
, vol.72
, Issue.1
, pp. 72-85
-
-
Cohen, S.1
Gabel, H.W.2
Hemberg, M.3
Hutchinson, A.N.4
Sadacca, L.A.5
Ebert, D.H.6
Harmin, D.A.7
Greenberg, R.S.8
Verdine, V.K.9
Zhou, Z.10
Wetsel, W.C.11
West, A.E.12
Greenberg, M.E.13
-
81
-
-
33847266846
-
Reversal of neurological defects in a mouse model of Rett syndrome
-
DOI 10.1126/science.1138389
-
Guy J, Gan J, Selfridge J, Cobb S, Bird A (2007) Reversal of neurological defects in a mouse model of Rett syndrome. Science 315(5815):1143-1147. doi: 10.1126/science.1138389 (Pubitemid 46328028)
-
(2007)
Science
, vol.315
, Issue.5815
, pp. 1143-1147
-
-
Guy, J.1
Gan, J.2
Selfridge, J.3
Cobb, S.4
Bird, A.5
-
82
-
-
33846924001
-
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2
-
DOI 10.1073/pnas.0610593104
-
Giacometti E, Luikenhuis S, Beard C, Jaenisch R (2007) Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proc Natl Acad Sci USA 104(6):1931-1936. doi: 10.1073/pnas.0610593104 (Pubitemid 46239881)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.6
, pp. 1931-1936
-
-
Giacometti, E.1
Luikenhuis, S.2
Beard, C.3
Jaenisch, R.4
-
83
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
10.1016/j.cell.2011.11.054 1:CAS:528:DC%2BC3MXhs1Ort73M 3252821 22196727
-
Yildirim O, Li R, Hung JH, Chen PB, Dong X, Ee LS, Weng Z, Rando OJ, Fazzio TG (2011) Mbd3/NURD complex regulates expression of 5- hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147(7):1498-1510. doi: 10.1016/j.cell.2011.11.054
-
(2011)
Cell
, vol.147
, Issue.7
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
Chen, P.B.4
Dong, X.5
Ee, L.S.6
Weng, Z.7
Rando, O.J.8
Fazzio, T.G.9
-
84
-
-
84874771985
-
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
-
10.1016/j.cell.2013.02.004 1:CAS:528:DC%2BC3sXjtVShtbY%3D 23434322
-
Spruijt CG, Gnerlich F, Smits AH, Pfaffeneder T, Jansen PW, Bauer C, Munzel M, Wagner M, Muller M, Khan F, Eberl HC, Mensinga A, Brinkman AB, Lephikov K, Muller U, Walter J, Boelens R, van Ingen H, Leonhardt H, Carell T, Vermeulen M (2013) Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell 152(5):1146-1159. doi: 10.1016/j.cell.2013.02.004
-
(2013)
Cell
, vol.152
, Issue.5
, pp. 1146-1159
-
-
Spruijt, C.G.1
Gnerlich, F.2
Smits, A.H.3
Pfaffeneder, T.4
Jansen, P.W.5
Bauer, C.6
Munzel, M.7
Wagner, M.8
Muller, M.9
Khan, F.10
Eberl, H.C.11
Mensinga, A.12
Brinkman, A.B.13
Lephikov, K.14
Muller, U.15
Walter, J.16
Boelens, R.17
Van Ingen, H.18
Leonhardt, H.19
Carell, T.20
Vermeulen, M.21
more..
-
85
-
-
33745593721
-
Generation of neuronal variability and complexity
-
DOI 10.1038/nature04959, PII N04959
-
Muotri AR, Gage FH (2006) Generation of neuronal variability and complexity. Nature 441(7097):1087-1093. doi: 10.1038/nature04959 (Pubitemid 43990721)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1087-1093
-
-
Muotri, A.R.1
Gage, F.H.2
-
86
-
-
20544466648
-
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
-
DOI 10.1038/nature03663
-
Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH (2005) Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature 435(7044):903-910. doi: 10.1038/nature03663 (Pubitemid 40896309)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 903-910
-
-
Muotri, A.R.1
Chu, V.T.2
Marchetto, M.C.N.3
Deng, W.4
Moran, J.V.5
Gage, F.H.6
-
87
-
-
69349096044
-
L1 retrotransposition in human neural progenitor cells
-
10.1038/nature08248 1:CAS:528:DC%2BD1MXpsVersLc%3D 2909034 19657334
-
Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH (2009) L1 retrotransposition in human neural progenitor cells. Nature 460(7259):1127-1131. doi: 10.1038/nature08248
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1127-1131
-
-
Coufal, N.G.1
Garcia-Perez, J.L.2
Peng, G.E.3
Yeo, G.W.4
Mu, Y.5
Lovci, M.T.6
Morell, M.7
O'Shea, K.S.8
Moran, J.V.9
Gage, F.H.10
-
88
-
-
25844487226
-
Diseases of unstable repeat expansion: Mechanisms and common principles
-
DOI 10.1038/nrg1691
-
Gatchel JR, Zoghbi HY (2005) Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet 6(10):743-755. doi: 10.1038/nrg1691 (Pubitemid 41400832)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.10
, pp. 743-755
-
-
Gatchel, J.R.1
Zoghbi, H.Y.2
-
89
-
-
77949775195
-
Repeat expansion disease: Progress and puzzles in disease pathogenesis
-
10.1038/nrg2748 20177426
-
La Spada AR, Taylor JP (2010) Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat Rev Genet 11(4):247-258. doi: 10.1038/nrg2748
-
(2010)
Nat Rev Genet
, vol.11
, Issue.4
, pp. 247-258
-
-
La Spada, A.R.1
Taylor, J.P.2
-
90
-
-
34547681603
-
Pur α Binds to rCGG Repeats and Modulates Repeat-Mediated Neurodegeneration in a Drosophila Model of Fragile X Tremor/Ataxia Syndrome
-
DOI 10.1016/j.neuron.2007.07.020, PII S0896627307005417
-
Jin P, Duan R, Qurashi A, Qin Y, Tian D, Rosser TC, Liu H, Feng Y, Warren ST (2007) Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome. Neuron 55(4):556-564. doi: 10.1016/j.neuron.2007.07.020 (Pubitemid 47223639)
-
(2007)
Neuron
, vol.55
, Issue.4
, pp. 556-564
-
-
Jin, P.1
Duan, R.2
Qurashi, A.3
Qin, Y.4
Tian, D.5
Rosser, T.C.6
Liu, H.7
Feng, Y.8
Warren, S.T.9
-
91
-
-
34547697173
-
RNA-Binding Proteins hnRNP A2/B1 and CUGBP1 Suppress Fragile X CGG Premutation Repeat-Induced Neurodegeneration in a Drosophila Model of FXTAS
-
DOI 10.1016/j.neuron.2007.07.021, PII S0896627307005429
-
Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J (2007) RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron 55(4):565-571. doi: 10.1016/j.neuron.2007.07.021 (Pubitemid 47223640)
-
(2007)
Neuron
, vol.55
, Issue.4
, pp. 565-571
-
-
Sofola, O.A.1
Jin, P.2
Qin, Y.3
Duan, R.4
Liu, H.5
De Haro, M.6
Nelson, D.L.7
Botas, J.8
-
92
-
-
84873477433
-
Extensive changes in DNA methylation are associated with expression of mutant huntingtin
-
10.1073/pnas.1221292110 1:CAS:528:DC%2BC3sXjtVertrk%3D 23341638
-
Ng CW, Yildirim F, Yap YS, Dalin S, Matthews BJ, Velez PJ, Labadorf A, Housman DE, Fraenkel E (2013) Extensive changes in DNA methylation are associated with expression of mutant huntingtin. Proc Natl Acad Sci USA 110(6):2354-2359. doi: 10.1073/pnas.1221292110
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.6
, pp. 2354-2359
-
-
Ng, C.W.1
Yildirim, F.2
Yap, Y.S.3
Dalin, S.4
Matthews, B.J.5
Velez, P.J.6
Labadorf, A.7
Housman, D.E.8
Fraenkel, E.9
-
93
-
-
0042759661
-
The contribution of cis-elements to disease-associated repeat instability: Clinical and experimental evidence
-
DOI 10.1159/000072837
-
Cleary JD, Pearson CE (2003) The contribution of cis-elements to disease-associated repeat instability: clinical and experimental evidence. Cytogenet Genome Res 100(1-4):25-55. doi: 72837 (Pubitemid 37467789)
-
(2003)
Cytogenetic and Genome Research
, vol.100
, Issue.1-4
, pp. 25-55
-
-
Cleary, J.D.1
Pearson, C.E.2
-
94
-
-
0025905795
-
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
-
Verkerk AJ, Pieretti M, Sutcliffe JS, Fu YH, Kuhl DP, Pizzuti A, Reiner O, Richards S, Victoria MF, Zhang FP et al (1991) Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65(5):905-914 (Pubitemid 121001321)
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 905-914
-
-
Verkerk, A.J.M.H.1
Pieretti, M.2
Sutcliffe, J.S.3
Fu, Y.-H.4
Kuhl, D.P.A.5
Pizzuti, A.6
Reiner, O.7
Richards, S.8
Victoria, M.F.9
Zhang, F.10
Eussen, B.E.11
Van Ommen, G.-J.B.12
Blonden, L.A.J.13
Riggins, G.J.14
Chastain, J.L.15
Kunst, C.B.16
Galjaard, H.17
Caskey, C.T.18
Nelson, D.L.19
Oostra, B.A.20
Warren, S.T.21
more..
-
95
-
-
7944232720
-
RNA and microRNAs in fragile X mental retardation
-
DOI 10.1038/ncb1104-1048
-
Jin P, Alisch RS, Warren ST (2004) RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 6(11):1048-1053. doi: 10.1038/ncb1104-1048 (Pubitemid 39468005)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.11
, pp. 1048-1053
-
-
Jin, P.1
Alisch, R.S.2
Warren, S.T.3
-
96
-
-
0026339303
-
Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome
-
Oberle I, Rousseau F, Heitz D, Kretz C, Devys D, Hanauer A, Boue J, Bertheas MF, Mandel JL (1991) Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252(5009):1097-1102 (Pubitemid 21917021)
-
(1991)
Science
, vol.252
, Issue.5009
, pp. 1097-1102
-
-
Oberle, I.1
Rousseau, F.2
Heitz, D.3
Kretz, C.4
Devys, D.5
Hanauer, A.6
Boue, J.7
Bertheas, M.F.8
Mandel, J.L.9
-
97
-
-
84555189745
-
DNA methylation: TET proteins-guardians of CpG islands?
-
10.1038/embor.2011.233 1:CAS:528:DC%2BC3MXhs1OltbbI 3246258
-
Williams K, Christensen J, Helin K (2012) DNA methylation: TET proteins-guardians of CpG islands? EMBO Rep 13(1):28-35. doi: 10.1038/embor.2011.233
-
(2012)
EMBO Rep
, vol.13
, Issue.1
, pp. 28-35
-
-
Williams, K.1
Christensen, J.2
Helin, K.3
-
98
-
-
84860749868
-
Tet family proteins and 5-hydroxymethylcytosine in development and disease
-
10.1242/dev.070771 1:CAS:528:DC%2BC38XhtVGlsLrL 22569552
-
Tan L, Shi YG (2012) Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development 139(11):1895-1902. doi: 10.1242/dev.070771
-
(2012)
Development
, vol.139
, Issue.11
, pp. 1895-1902
-
-
Tan, L.1
Shi, Y.G.2
-
99
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
10.1038/nrg3080 1:CAS:528:DC%2BC3MXhsVKjtr7L
-
Branco MR, Ficz G, Reik W (2012) Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 13(1):7-13. doi: 10.1038/nrg3080
-
(2012)
Nat Rev Genet
, vol.13
, Issue.1
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
100
-
-
80052303426
-
TET family proteins and their role in stem cell differentiation and transformation
-
10.1016/j.stem.2011.08.007 1:CAS:528:DC%2BC3MXhtFeks7nE 3244690 21885017
-
Cimmino L, Abdel-Wahab O, Levine RL, Aifantis I (2011) TET family proteins and their role in stem cell differentiation and transformation. Cell Stem Cell 9(3):193-204. doi: 10.1016/j.stem.2011.08.007
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 193-204
-
-
Cimmino, L.1
Abdel-Wahab, O.2
Levine, R.L.3
Aifantis, I.4
-
101
-
-
79960626636
-
The discovery of 5-formylcytosine in embryonic stem cell DNA
-
10.1002/anie.201103899 1:CAS:528:DC%2BC3MXotFygtbs%3D
-
Pfaffeneder T, Hackner B, Truss M, Munzel M, Muller M, Deiml CA, Hagemeier C, Carell T (2011) The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem 50(31):7008-7012. doi: 10.1002/anie.201103899
-
(2011)
Angew Chem
, vol.50
, Issue.31
, pp. 7008-7012
-
-
Pfaffeneder, T.1
Hackner, B.2
Truss, M.3
Munzel, M.4
Muller, M.5
Deiml, C.A.6
Hagemeier, C.7
Carell, T.8
-
102
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
10.1016/j.cell.2011.03.022 1:CAS:528:DC%2BC3MXlsFShsrs%3D 3088758 21496894
-
Guo JU, Su Y, Zhong C, Ming GL, Song H (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145(3):423-434. doi: 10.1016/j.cell.2011.03.022
-
(2011)
Cell
, vol.145
, Issue.3
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
103
-
-
84862776719
-
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine- modified DNA
-
10.1038/nchembio.914 1:CAS:528:DC%2BC38XitFalsro%3D 3307914 22327402
-
Zhang L, Lu X, Lu J, Liang H, Dai Q, Xu GL, Luo C, Jiang H, He C (2012) Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol 8(4):328-330. doi: 10.1038/nchembio.914
-
(2012)
Nat Chem Biol
, vol.8
, Issue.4
, pp. 328-330
-
-
Zhang, L.1
Lu, X.2
Lu, J.3
Liang, H.4
Dai, Q.5
Xu, G.L.6
Luo, C.7
Jiang, H.8
He, C.9
-
104
-
-
84860221291
-
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
-
10.1093/nar/gks155 1:CAS:528:DC%2BC38XotlCntbg%3D 3367191 22362737
-
Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X (2012) Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Res 40(11):4841-4849. doi: 10.1093/nar/gks155
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.11
, pp. 4841-4849
-
-
Hashimoto, H.1
Liu, Y.2
Upadhyay, A.K.3
Chang, Y.4
Howerton, S.B.5
Vertino, P.M.6
Zhang, X.7
Cheng, X.8
-
105
-
-
82655187105
-
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development
-
10.1038/cr.2011.189 1:CAS:528:DC%2BC3MXhsFKms7nK 22124233
-
Inoue A, Shen L, Dai Q, He C, Zhang Y (2011) Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res 21(12):1670-1676. doi: 10.1038/cr.2011.189
-
(2011)
Cell Res
, vol.21
, Issue.12
, pp. 1670-1676
-
-
Inoue, A.1
Shen, L.2
Dai, Q.3
He, C.4
Zhang, Y.5
-
106
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W, Niveleau A, Walter J, Fundele R, Haaf T (2000) Demethylation of the zygotic paternal genome. Nature 403(6769):501-502. doi: 10.1038/35000654 (Pubitemid 30082186)
-
(2000)
Nature
, vol.403
, Issue.6769
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
107
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
DOI 10.1016/S0960-9822(00)00448-6
-
Oswald J, Engemann S, Lane N, Mayer W, Olek A, Fundele R, Dean W, Reik W, Walter J (2000) Active demethylation of the paternal genome in the mouse zygote. Curr Biol 10(8):475-478 (Pubitemid 30247337)
-
(2000)
Current Biology
, vol.10
, Issue.8
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
Mayer, W.4
Olek, A.5
Fundele, R.6
Dean, W.7
Reik, W.8
Walter, J.9
-
108
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
10.1038/nature10443 1:CAS:528:DC%2BC3MXhtFersL7M 21892189
-
Gu TP, Guo F, Yang H, Wu HP, Xu GF, Liu W, Xie ZG, Shi L, He X, Jin SG, Iqbal K, Shi YG, Deng Z, Szabo PE, Pfeifer GP, Li J, Xu GL (2011) The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477(7366):606-610. doi: 10.1038/nature10443
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
Iqbal, K.11
Shi, Y.G.12
Deng, Z.13
Szabo, P.E.14
Pfeifer, G.P.15
Li, J.16
Xu, G.L.17
-
109
-
-
84875949201
-
Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells
-
10.1016/j.stem.2013.01.016 23415914
-
Vincent JJ, Huang Y, Chen PY, Feng S, Calvopina JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT (2013) Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells. Cell Stem Cell. doi: 10.1016/j.stem.2013.01.016
-
(2013)
Cell Stem Cell
-
-
Vincent, J.J.1
Huang, Y.2
Chen, P.Y.3
Feng, S.4
Calvopina, J.H.5
Nee, K.6
Lee, S.A.7
Le, T.8
Yoon, A.J.9
Faull, K.10
Fan, G.11
Rao, A.12
Jacobsen, S.E.13
Pellegrini, M.14
Clark, A.T.15
-
110
-
-
84872770694
-
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine
-
10.1126/science.1229277 3847602
-
Hackett JA, Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA (2012) Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science. doi: 10.1126/science.1229277
-
(2012)
Science
-
-
Hackett, J.A.1
Sengupta, R.2
Zylicz, J.J.3
Murakami, K.4
Lee, C.5
Down, T.A.6
Surani, M.A.7
-
111
-
-
0035853467
-
Local DNA demethylation in vertebrates: How could it be performed and targeted?
-
DOI 10.1016/S0014-5793(01)02328-6, PII S0014579301023286
-
Kress C, Thomassin H, Grange T (2001) Local DNA demethylation in vertebrates: how could it be performed and targeted? FEBS Lett 494(3):135-140 (Pubitemid 32322670)
-
(2001)
FEBS Letters
, vol.494
, Issue.3
, pp. 135-140
-
-
Kress, C.1
Thomassin, H.2
Grange, T.3
-
112
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
DOI 10.1038/nature05515, PII NATURE05515
-
Barreto G, Schafer A, Marhold J, Stach D, Swaminathan SK, Handa V, Doderlein G, Maltry N, Wu W, Lyko F, Niehrs C (2007) Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445(7128):671-675. doi: 10.1038/nature05515 (Pubitemid 46232889)
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
Stach, D.4
Swaminathan, S.K.5
Handa, V.6
Doderlein, G.7
Maltry, N.8
Wu, W.9
Lyko, F.10
Niehrs, C.11
-
113
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
10.1126/science.1166859 1:CAS:528:DC%2BD1MXitVyntrg%3D 2726986 19119186
-
Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, Pow-Anpongkul N, Flavell RA, Lu B, Ming GL, Song H (2009) Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323(5917):1074-1077. doi: 10.1126/science.1166859
-
(2009)
Science
, vol.323
, Issue.5917
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
Kitabatake, Y.4
Chang, M.L.5
Pow-Anpongkul, N.6
Flavell, R.A.7
Lu, B.8
Ming, G.L.9
Song, H.10
-
114
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
10.1016/j.ccr.2010.12.014 1:CAS:528:DC%2BC3MXpvValsQ%3D%3D 3229304 21251613
-
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19(1):17-30. doi: 10.1016/j.ccr.2010.12.014
-
(2011)
Cancer Cell
, vol.19
, Issue.1
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.H.6
Ito, S.7
Yang, C.8
Wang, P.9
Xiao, M.T.10
Liu, L.X.11
Jiang, W.Q.12
Liu, J.13
Zhang, J.Y.14
Wang, B.15
Frye, S.16
Zhang, Y.17
Xu, Y.H.18
Lei, Q.Y.19
Guan, K.L.20
Zhao, S.M.21
Xiong, Y.22
more..
-
115
-
-
84875496294
-
(R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible
-
10.1126/science.1231677 3836459 23393090
-
Losman JA, Looper R, Koivunen P, Lee S, Schneider RK, McMahon C, Cowley G, Root D, Ebert BL, Kaelin WG Jr (2013) (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. doi: 10.1126/science.1231677
-
(2013)
Science
-
-
Losman, J.A.1
Looper, R.2
Koivunen, P.3
Lee, S.4
Schneider, R.K.5
McMahon, C.6
Cowley, G.7
Root, D.8
Ebert, B.L.9
Kaelin, Jr.W.G.10
-
116
-
-
84879431557
-
Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2 and DNMT3A
-
10.1182/blood-2012-06-436782
-
Liang DC, Liu HC, Yang CP, Jaing TH, Hung IJ, Yeh TC, Chen SH, Hou JY, Huang YJ, Shih YS, Huang YH, Lin TH, Shih LY (2013) Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2 and DNMT3A. Blood. doi: 10.1182/blood-2012-06-436782
-
(2013)
Blood
-
-
Liang, D.C.1
Liu, H.C.2
Yang, C.P.3
Jaing, T.H.4
Hung, I.J.5
Yeh, T.C.6
Chen, S.H.7
Hou, J.Y.8
Huang, Y.J.9
Shih, Y.S.10
Huang, Y.H.11
Lin, T.H.12
Shih, L.Y.13
-
117
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
10.1016/j.cell.2012.07.033 1:CAS:528:DC%2BC38XhtlKrsr%2FI 3770275 22980977
-
Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG (2012) Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 150(6):1135-1146. doi: 10.1016/j.cell.2012.07.033
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
Wu, F.4
Larson, A.5
Dresser, K.6
Xu, W.7
Tan, L.8
Hu, Y.9
Zhan, Q.10
Lee, C.W.11
Hu, D.12
Lian, B.Q.13
Kleffel, S.14
Yang, Y.15
Neiswender, J.16
Khorasani, A.J.17
Fang, R.18
Lezcano, C.19
Duncan, L.M.20
Scolyer, R.A.21
Thompson, J.F.22
Kakavand, H.23
Houvras, Y.24
Zon, L.I.25
Mihm, Jr.M.C.26
Kaiser, U.B.27
Schatton, T.28
Woda, B.A.29
Murphy, G.F.30
Shi, Y.G.31
more..
-
118
-
-
84860528433
-
IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma
-
10.1158/1078-0432.CCR-11-2977 1:CAS:528:DC%2BC38XmsFejurY%3D 22415316
-
Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT (2012) IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma. Clin Cancer Res 18(9):2490-2501. doi: 10.1158/1078-0432.CCR-11-2977
-
(2012)
Clin Cancer Res
, vol.18
, Issue.9
, pp. 2490-2501
-
-
Gorovets, D.1
Kannan, K.2
Shen, R.3
Kastenhuber, E.R.4
Islamdoust, N.5
Campos, C.6
Pentsova, E.7
Heguy, A.8
Jhanwar, S.C.9
Mellinghoff, I.K.10
Chan, T.A.11
Huse, J.T.12
-
119
-
-
84874266225
-
Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells
-
10.1016/j.molcel.2012.12.019 23352454
-
Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K, Cuomo A, Roberto A, Christensen J, Bonaldi T, Helin K, Pasini D (2013) Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells. Mol Cell. doi: 10.1016/j.molcel.2012.12.019
-
(2013)
Mol Cell
-
-
Vella, P.1
Scelfo, A.2
Jammula, S.3
Chiacchiera, F.4
Williams, K.5
Cuomo, A.6
Roberto, A.7
Christensen, J.8
Bonaldi, T.9
Helin, K.10
Pasini, D.11
-
120
-
-
84875218124
-
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
-
10.1038/emboj.2012.357 23353889
-
Deplus R, Delatte B, Schwinn MK, Defrance M, Mendez J, Murphy N, Dawson MA, Volkmar M, Putmans P, Calonne E, Shih AH, Levine RL, Bernard O, Mercher T, Solary E, Urh M, Daniels DL, Fuks F (2013) TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J. doi: 10.1038/emboj.2012.357
-
(2013)
EMBO J
-
-
Deplus, R.1
Delatte, B.2
Schwinn, M.K.3
Defrance, M.4
Mendez, J.5
Murphy, N.6
Dawson, M.A.7
Volkmar, M.8
Putmans, P.9
Calonne, E.10
Shih, A.H.11
Levine, R.L.12
Bernard, O.13
Mercher, T.14
Solary, E.15
Urh, M.16
Daniels, D.L.17
Fuks, F.18
-
121
-
-
84872953223
-
TET2 promotes histone O-GlcNAcylation during gene transcription
-
10.1038/nature11742
-
Chen Q, Chen Y, Bian C, Fujiki R, Yu X (2012) TET2 promotes histone O-GlcNAcylation during gene transcription. Nature. doi: 10.1038/nature11742
-
(2012)
Nature
-
-
Chen, Q.1
Chen, Y.2
Bian, C.3
Fujiki, R.4
Yu, X.5
-
122
-
-
59949096567
-
O-GLcNAc post-translational modifications regulate the entry of neurons into an axon branching program
-
10.1002/dneu.20695 1:CAS:528:DC%2BD1MXjt1Chsb0%3D 2747243 19086029
-
Francisco H, Kollins K, Varghis N, Vocadlo D, Vosseller K, Gallo G (2009) O-GLcNAc post-translational modifications regulate the entry of neurons into an axon branching program. Dev Neurobiol 69(2-3):162-173. doi: 10.1002/dneu.20695
-
(2009)
Dev Neurobiol
, vol.69
, Issue.2-3
, pp. 162-173
-
-
Francisco, H.1
Kollins, K.2
Varghis, N.3
Vocadlo, D.4
Vosseller, K.5
Gallo, G.6
-
123
-
-
84865191053
-
Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain
-
10.1371/journal.pone.0043724 1:CAS:528:DC%2BC38Xht1GqsLnO 3425547 22928023
-
Liu Y, Li X, Yu Y, Shi J, Liang Z, Run X, Li Y, Dai CL, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX (2012) Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain. PLoS ONE 7(8):e43724. doi: 10.1371/journal.pone.0043724
-
(2012)
PLoS ONE
, vol.7
, Issue.8
, pp. 43724
-
-
Liu, Y.1
Li, X.2
Yu, Y.3
Shi, J.4
Liang, Z.5
Run, X.6
Li, Y.7
Dai, C.L.8
Grundke-Iqbal, I.9
Iqbal, K.10
Liu, F.11
Gong, C.X.12
-
124
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis
-
10.1016/j.celrep.2013.01.011 3582786
-
Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, Jui J, Jin SG, Jiang Y, Pfeifer GP, Lu Q (2013) Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis. Cell Rep. doi: 10.1016/j.celrep.2013.01.011
-
(2013)
Cell Rep
-
-
Hahn, M.A.1
Qiu, R.2
Wu, X.3
Li, A.X.4
Zhang, H.5
Wang, J.6
Jui, J.7
Jin, S.G.8
Jiang, Y.9
Pfeifer, G.P.10
Lu, Q.11
-
125
-
-
84870883633
-
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus Eye and neural development
-
10.1016/j.cell.2012.11.014 1:CAS:528:DC%2BC38XhvVaisrbI 3705565 23217707
-
Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, Ma C, Barbara A, Veenstra GJ, Xu G, Kaiser UB, Liu XS, Sugrue SP, He X, Min J, Kato Y, Shi YG (2012) Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus Eye and neural development. Cell 151(6):1200-1213. doi: 10.1016/j.cell.2012.11. 014
-
(2012)
Cell
, vol.151
, Issue.6
, pp. 1200-1213
-
-
Xu, Y.1
Xu, C.2
Kato, A.3
Tempel, W.4
Abreu, J.G.5
Bian, C.6
Hu, Y.7
Hu, D.8
Zhao, B.9
Cerovina, T.10
Diao, J.11
Wu, F.12
He, H.H.13
Cui, Q.14
Clark, E.15
Ma, C.16
Barbara, A.17
Veenstra, G.J.18
Xu, G.19
Kaiser, U.B.20
Liu, X.S.21
Sugrue, S.P.22
He, X.23
Min, J.24
Kato, Y.25
Shi, Y.G.26
more..
-
126
-
-
84875370281
-
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
-
10.1038/nature11925 3606645
-
Costa Y, Ding J, Theunissen TW, Faiola F, Hore TA, Shliaha PV, Fidalgo M, Saunders A, Lawrence M, Dietmann S, Das S, Levasseur DN, Li Z, Xu M, Reik W, Silva JC, Wang J (2013) NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature. doi: 10.1038/nature11925
-
(2013)
Nature
-
-
Costa, Y.1
Ding, J.2
Theunissen, T.W.3
Faiola, F.4
Hore, T.A.5
Shliaha, P.V.6
Fidalgo, M.7
Saunders, A.8
Lawrence, M.9
Dietmann, S.10
Das, S.11
Levasseur, D.N.12
Li, Z.13
Xu, M.14
Reik, W.15
Silva, J.C.16
Wang, J.17
-
127
-
-
84865486793
-
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
-
10.1038/nature11333 1:CAS:528:DC%2BC38Xht1Wkt7bO 22902501
-
Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, Levine RL, Nik S, Chen EI, Abeliovich A (2012) Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2. Nature 488(7413):652-655. doi: 10.1038/nature11333
-
(2012)
Nature
, vol.488
, Issue.7413
, pp. 652-655
-
-
Doege, C.A.1
Inoue, K.2
Yamashita, T.3
Rhee, D.B.4
Travis, S.5
Fujita, R.6
Guarnieri, P.7
Bhagat, G.8
Vanti, W.B.9
Shih, A.10
Levine, R.L.11
Nik, S.12
Chen, E.I.13
Abeliovich, A.14
-
128
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
10.1038/nature10066 1:CAS:528:DC%2BC3MXkslCmsLo%3D 3408592 21490601
-
Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J, Helin K (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473(7347):343-348. doi: 10.1038/nature10066
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
Helin, K.7
-
129
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
10.1016/j.molcel.2011.04.005 1:CAS:528:DC%2BC3MXmsVChtLg%3D 3099128 21514197
-
Xu Y, Wu F, Tan L, Kong L, Xiong L, Deng J, Barbera AJ, Zheng L, Zhang H, Huang S, Min J, Nicholson T, Chen T, Xu G, Shi Y, Zhang K, Shi YG (2011) Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 42(4):451-464. doi: 10.1016/j.molcel.2011. 04.005
-
(2011)
Mol Cell
, vol.42
, Issue.4
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
Deng, J.6
Barbera, A.J.7
Zheng, L.8
Zhang, H.9
Huang, S.10
Min, J.11
Nicholson, T.12
Chen, T.13
Xu, G.14
Shi, Y.15
Zhang, K.16
Shi, Y.G.17
-
130
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
10.1016/j.stem.2011.01.008 1:CAS:528:DC%2BC3MXhsFOkurk%3D 3134318 21295276
-
Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A (2011) Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8(2):200-213. doi: 10.1016/j.stem.2011.01.008
-
(2011)
Cell Stem Cell
, vol.8
, Issue.2
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
Huang, Y.4
Cunniff, K.5
Nardone, J.6
Laiho, A.7
Tahiliani, M.8
Sommer, C.A.9
Mostoslavsky, G.10
Lahesmaa, R.11
Orkin, S.H.12
Rodig, S.J.13
Daley, G.Q.14
Rao, A.15
-
131
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
10.1016/j.stem.2011.07.010 1:CAS:528:DC%2BC3MXpvFGit74%3D 3154739 21816367
-
Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R (2011) Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9(2):166-175. doi: 10.1016/j.stem.2011.07.010
-
(2011)
Cell Stem Cell
, vol.9
, Issue.2
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
Hu, Y.C.4
Markoulaki, S.5
Cheng, A.W.6
Gao, Q.7
Kim, J.8
Choi, S.W.9
Page, D.C.10
Jaenisch, R.11
-
132
-
-
84873707539
-
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development
-
10.1016/j.devcel.2012.12.015 23352810
-
Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R (2013) Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev Cell. doi: 10.1016/j.devcel.2012.12.015
-
(2013)
Dev Cell
-
-
Dawlaty, M.M.1
Breiling, A.2
Le, T.3
Raddatz, G.4
Barrasa, M.I.5
Cheng, A.W.6
Gao, Q.7
Powell, B.E.8
Li, Z.9
Xu, M.10
Faull, K.F.11
Lyko, F.12
Jaenisch, R.13
-
133
-
-
84883012277
-
Genome-wide loss of 5-hmC is a novel epigenetic feature of huntington's disease
-
10.1093/hmg/ddt214
-
Wang F, Yang Y, Lin X, Wang JQ, Wu YS, Xie W, Wang D, Zhu S, Liao YQ, Sun Q, Yang YG, Guo C, Han C, Tang TS (2013) Genome-wide loss of 5-hmC is a novel epigenetic feature of huntington's disease. Hum Mol Genet. doi: 10.1093/hmg/ddt214
-
(2013)
Hum Mol Genet
-
-
Wang, F.1
Yang, Y.2
Lin, X.3
Wang, J.Q.4
Wu, Y.S.5
Xie, W.6
Wang, D.7
Zhu, S.8
Liao, Y.Q.9
Sun, Q.10
Yang, Y.G.11
Guo, C.12
Han, C.13
Tang, T.S.14
-
134
-
-
84876907152
-
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
-
10.1016/j.cell.2013.04.001
-
Song CX, Szulwach KE, Dai Q, Fu Y, Mao SQ, Lin L, Street C, Li Y, Poidevin M, Wu H, Gao J, Liu P, Li L, Xu GL, Jin P, He C (2013) Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. doi: 10.1016/j.cell.2013.04.001
-
(2013)
Cell
-
-
Song, C.X.1
Szulwach, K.E.2
Dai, Q.3
Fu, Y.4
Mao, S.Q.5
Lin, L.6
Street, C.7
Li, Y.8
Poidevin, M.9
Wu, H.10
Gao, J.11
Liu, P.12
Li, L.13
Xu, G.L.14
Jin, P.15
He, C.16
-
135
-
-
84876946045
-
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
-
10.1016/j.cell.2013.04.002 3687516
-
Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC, Fung HL, Zhang K, Zhang Y (2013) Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell. doi: 10.1016/j.cell.2013.04.002
-
(2013)
Cell
-
-
Shen, L.1
Wu, H.2
Diep, D.3
Yamaguchi, S.4
D'Alessio, A.C.5
Fung, H.L.6
Zhang, K.7
Zhang, Y.8
-
136
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
10.1038/nature09586 1:CAS:528:DC%2BC3cXhtl2jtrrP 3003755 21057493
-
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468(7325):839-843. doi: 10.1038/nature09586
-
(2010)
Nature
, vol.468
, Issue.7325
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
An, J.7
Lamperti, E.D.8
Koh, K.P.9
Ganetzky, R.10
Liu, X.S.11
Aravind, L.12
Agarwal, S.13
Maciejewski, J.P.14
Rao, A.15
-
137
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
10.1016/j.ccr.2011.06.001 1:CAS:528:DC%2BC3MXoslCms7w%3D 3194039 21723200
-
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL (2011) Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20(1):11-24. doi: 10.1016/j.ccr.2011.06.001
-
(2011)
Cancer Cell
, vol.20
, Issue.1
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
Vasanthakumar, A.8
Patel, J.9
Zhao, X.10
Perna, F.11
Pandey, S.12
Madzo, J.13
Song, C.14
Dai, Q.15
He, C.16
Ibrahim, S.17
Beran, M.18
Zavadil, J.19
Nimer, S.D.20
Melnick, A.21
Godley, L.A.22
Aifantis, I.23
Levine, R.L.24
more..
-
138
-
-
80052284526
-
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
10.1073/pnas.1112317108 1:CAS:528:DC%2BC3MXhtFCltbbE 21873190
-
Ko M, Bandukwala HS, An J, Lamperti ED, Thompson EC, Hastie R, Tsangaratou A, Rajewsky K, Koralov SB, Rao A (2011) Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc Natl Acad Sci USA 108(35):14566-14571. doi: 10.1073/pnas.1112317108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.35
, pp. 14566-14571
-
-
Ko, M.1
Bandukwala, H.S.2
An, J.3
Lamperti, E.D.4
Thompson, E.C.5
Hastie, R.6
Tsangaratou, A.7
Rajewsky, K.8
Koralov, S.B.9
Rao, A.10
-
139
-
-
84877693964
-
Ascorbate induces Ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
-
10.1074/jbc.C113.464800
-
Minor EA, Court BL, Young JI, Wang G (2013) Ascorbate induces Ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J Biol Chem. doi: 10.1074/jbc.C113.464800
-
(2013)
J Biol Chem
-
-
Minor, E.A.1
Court, B.L.2
Young, J.I.3
Wang, G.4
|