Biological relevance and therapeutic potential of the hypusine modification system

Journal of Biological Chemistry

Volumn 290, Issue 30, 2015, Pages 18343-18360

  Pällmann, Nora ^a,b   Braig, Melanie ^a,c   Sievert, Henning ^a   Preukschas, Michael ^a,d   Hermans Borgmeyer, Irm ^a   Schweizer, Michaela ^a   Nagel, Claus Henning ^b   Neumann, Melanie ^a,e   Wild, Peter ^c   Haralambieva, Eugenia ^c   Hagel, Christian ^a   Bokemeyer, Carsten ^a   Hauber, Joachim ^b   Balabanov, Stefan ^a,c  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d Institute for Hematopathology   (Germany)

^e EVOTEC AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; COMPLEX NETWORKS; DISEASES; ENZYMES; MAMMALS;

BIOINFORMATIC ANALYSIS; DEOXYHYPUSINE SYNTHASE; EUKARYOTIC INITIATION FACTOR; PROTEIN-PROTEIN INTERACTION NETWORKS; THERAPEUTIC INTERVENTION; THERAPEUTIC POTENTIALS; THERAPEUTIC STRATEGY; TRANSLATIONAL REGULATION;

PROTEINS;

DEOXYHYPUSINE HYDROXYLASE; DEOXYHYPUSINE SYNTHASE; HYPUSINE; INITIATION FACTOR 5A; OXYGENASE; UNCLASSIFIED DRUG; EIF-5A2; INITIATION FACTOR; LYSINE; MIXED FUNCTION OXIDASE; OXIDOREDUCTASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; EMBRYO; FEMALE; KNOCKOUT MOUSE; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLINE RICH PROTEIN DOMAIN; PROTEIN DEPLETION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; ANALOGS AND DERIVATIVES; ANIMAL; GENETICS; HOMEOSTASIS; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY; PROTEIN PROCESSING; PROTEIN SYNTHESIS;

EUKARYOTA; MAMMALIA; MUS;

ANIMALS; HOMEOSTASIS; HUMANS; LYSINE; MICE; MICE, KNOCKOUT; MIXED FUNCTION OXYGENASES; NEOPLASMS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PEPTIDE INITIATION FACTORS; PROTEIN BIOSYNTHESIS; PROTEIN INTERACTION MAPS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84937722028     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.664490     Document Type: Article

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