Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1)

Biochemical Journal

Volumn 433, Issue 1, 2011, Pages 205-213

  Lee, Seung Bum ^a   Park, Jong Hwan ^a   Folk, John E ^b   Deck, Jason A ^b   Pegg, Anthony E ^c   Sokabe, Masaaki ^d   Fraser, Christopher S ^e   Park, Myung Hee ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acetylation; Eukaryotic translation initiation factor 5A (eIF5A); Hypusine; Polyamine metabolism; Post translational modification; Spermidine spermine N 1 acetyltransferase 1 (SSAT1)

Indexed keywords

DEOXYHYPUSINE; HYPUSINE; INITIATION FACTOR 5A; PUROMYCIN; SPERMIDINE DERIVATIVE; SPERMIDINE SPERMINE N1 ACETYLTRANSFERASE 1; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; COW; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; FEMALE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; ION EXCHANGE CHROMATOGRAPHY; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN TARGETING; SYNTHESIS; TESTIS;

ACETYLATION; ACETYLTRANSFERASES; ANIMALS; CATTLE; CELL LINE, TUMOR; HUMANS; LYSINE; PEPTIDE INITIATION FACTORS; PROTEIN BINDING; RNA-BINDING PROTEINS;

BOVINAE; EUKARYOTA;

EID: 79551488077     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101322     Document Type: Article

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