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Volumn 10, Issue 7, 2011, Pages 1043-1049

Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling

Author keywords

Cytokine; Diabetes; Hypusine; Inflammation; mRNA translation; Posttranslational modification

Indexed keywords

ANTIDIABETIC AGENT; DEOXYHYPUSINE SYNTHASE; GAMMA INTERFERON; GLUCOSE; HYPUSINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR 5A; INSULIN; INTERLEUKIN 1BETA; MESSENGER RNA; N' GUANYL 1,7 DIAMINOHEPTANE; TRANSFERASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79953662744     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.7.15206     Document Type: Review
Times cited : (24)

References (37)
  • 1
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • DOI 10.1172/JCI29103
    • Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest 2006; 116:1802-12. (Pubitemid 44033300)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 2
    • 77957655499 scopus 로고    scopus 로고
    • Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass
    • Fontés G, Zarrouki B, Hagman DK, Latour MG, Semache M, Roskens V, et al. Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass. Diabetologia 2010; 53:2369-79.
    • (2010) Diabetologia , vol.53 , pp. 2369-2379
    • Fontés, G.1    Zarrouki, B.2    Hagman, D.K.3    Latour, M.G.4    Semache, M.5    Roskens, V.6
  • 5
    • 34547638958 scopus 로고    scopus 로고
    • High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress-mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
    • DOI 10.2337/db07-0197
    • Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, et al. High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 2007; 56:2016-27. (Pubitemid 47201819)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2016-2027
    • Huang, C.-J.1    Lin, C.-Y.2    Haataja, L.3    Gurlo, T.4    Butler, A.E.5    Rizza, R.A.6    Butler, P.C.7
  • 6
    • 61449123871 scopus 로고    scopus 로고
    • Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
    • Zraika S, Hull RL, Udayasankar J, Aston-Mourney K, Subramanian SL, Kisilevsky R, et al. Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis. Diabetologia 2009; 52:626-35.
    • (2009) Diabetologia , vol.52 , pp. 626-635
    • Zraika, S.1    Hull, R.L.2    Udayasankar, J.3    Aston-Mourney, K.4    Subramanian, S.L.5    Kisilevsky, R.6
  • 7
    • 78650073927 scopus 로고    scopus 로고
    • An islet in distress: B cell failure in type 2 diabetes
    • Ogihara T, Mirmira RG. An islet in distress: B cell failure in type 2 diabetes. J Diab Invest 2010; 1:123-33.
    • (2010) J Diab Invest , vol.1 , pp. 123-133
    • Ogihara, T.1    Mirmira, R.G.2
  • 8
    • 38449122843 scopus 로고    scopus 로고
    • The role of nitric oxide and the unfolded protein response in cytokine-induced betacell death
    • Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA. The role of nitric oxide and the unfolded protein response in cytokine-induced betacell death. Diabetes 2008; 57:124-32.
    • (2008) Diabetes , vol.57 , pp. 124-132
    • Chambers, K.T.1    Unverferth, J.A.2    Weber, S.M.3    Wek, R.C.4    Urano, F.5    Corbett, J.A.6
  • 9
    • 70350451227 scopus 로고    scopus 로고
    • Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated {beta}-cells that is associated with irreversible DNA damage
    • Hughes KJ, Chambers KT, Meares GP, Corbett JA. Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated {beta}-cells that is associated with irreversible DNA damage. Am J Physiol Endocrinol Metab 2009.
    • (2009) Am J Physiol Endocrinol Metab
    • Hughes, K.J.1    Chambers, K.T.2    Meares, G.P.3    Corbett, J.A.4
  • 11
    • 77957787230 scopus 로고    scopus 로고
    • Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating
    • Perl S, Kushner JA, Buchholz BA, Meeker AK, Stein GM, Hsieh M, et al. Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating. J Clin Endocrinol Metab 2010; 95:234-9.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 234-239
    • Perl, S.1    Kushner, J.A.2    Buchholz, B.A.3    Meeker, A.K.4    Stein, G.M.5    Hsieh, M.6
  • 12
    • 0019749949 scopus 로고
    • The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex
    • Leiter EH, Coleman DL, Hummel KP. The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex. Diabetes 1981; 30:1029-34.
    • (1981) Diabetes , vol.30 , pp. 1029-1034
    • Leiter, E.H.1    Coleman, D.L.2    Hummel, K.P.3
  • 13
    • 0017880329 scopus 로고
    • Alteration of islet cell populations in spontaneously diabetic mice
    • Baetens D, Stefan Y, Ravazzola M, Malaisse-Lagae F, Coleman DL, Orci L. Alteration of islet cell populations in spontaneously diabetic mice. Diabetes 1978; 27:1-7. (Pubitemid 8293466)
    • (1978) Diabetes , vol.27 , Issue.1 , pp. 1-7
    • Baetens, D.1    Stefan, Y.2    Ravazzola, M.3
  • 14
    • 78650053328 scopus 로고    scopus 로고
    • Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes
    • Robbins RD, Tersey SA, Ogihara T, Gupta D, Farb TB, Ficorilli J, et al. Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes. J Biol Chem 2010; 285:39943-52.
    • (2010) J Biol Chem , vol.285 , pp. 39943-39952
    • Robbins, R.D.1    Tersey, S.A.2    Ogihara, T.3    Gupta, D.4    Farb, T.B.5    Ficorilli, J.6
  • 16
    • 77956311711 scopus 로고    scopus 로고
    • Eif5A promotes translation elongation, polysome disassembly and stress granule assembly
    • Li CH, Ohn T, Ivanov P, Tisdale S, Anderson P. Eif5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One 2010; 5:9942.
    • (2010) PLoS One , vol.5 , pp. 9942
    • Li, C.H.1    Ohn, T.2    Ivanov, P.3    Tisdale, S.4    Anderson, P.5
  • 17
    • 65549167195 scopus 로고    scopus 로고
    • Hypusine- Containing protein eif5a promotes translation elongation
    • Saini P, Eyler DE, Green R, Dever TE. Hypusine- Containing protein eif5a promotes translation elongation. Nature 2009; 459:118-21.
    • (2009) Nature , vol.459 , pp. 118-121
    • Saini, P.1    Eyler, D.E.2    Green, R.3    Dever, T.E.4
  • 18
    • 0028145708 scopus 로고
    • Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae
    • Kang HA, Hershey JW. Effect of initiation factor eif-5a depletion on protein synthesis and proliferation of saccharomyces cerevisiae. J Biol Chem 1994; 269:3934-40. (Pubitemid 24237736)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.6 , pp. 3934-3940
    • Kang, H.A.1    Hershey, J.W.B.2
  • 19
    • 0032809085 scopus 로고    scopus 로고
    • Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: Evidence for direct interaction with the export receptor CRM1
    • Rosorius O, Reichart B, Kratzer F, Heger P, Dabauvalle MC, Hauber J. Nuclear pore localization and nucleocytoplasmic transport of eif-5a: Evidence for direct interaction with the export receptor CRM1. J Cell Sci 1999; 112:2369-80. (Pubitemid 29381027)
    • (1999) Journal of Cell Science , vol.112 , Issue.14 , pp. 2369-2380
    • Rosorius, O.1    Reichart, B.2    Kratzer, F.3    Heger, P.4    Dabauvalle, M.-C.5    Hauber, J.6
  • 20
    • 0036935565 scopus 로고    scopus 로고
    • Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging
    • DOI 10.1002/jcb.10235
    • Jao DL, Yu Chen K. Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging. J Cell Biochem 2002; 86:590-600. (Pubitemid 36076175)
    • (2002) Journal of Cellular Biochemistry , vol.86 , Issue.3 , pp. 590-600
    • Jao, D.L.-E.1    Chen, K.Y.2
  • 22
    • 77953186469 scopus 로고    scopus 로고
    • The unique hypusine modification of eif5a promotes islet beta cell inflammation and dysfunction in mice
    • Maier B, Ogihara T, Trace AP, Tersey SA, Robbins RD, Chakrabarti SK, et al. The unique hypusine modification of eif5a promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest 2010; 120:2156-70.
    • (2010) J Clin Invest , vol.120 , pp. 2156-2170
    • Maier, B.1    Ogihara, T.2    Trace, A.P.3    Tersey, S.A.4    Robbins, R.D.5    Chakrabarti, S.K.6
  • 23
    • 77953039922 scopus 로고    scopus 로고
    • Functional significance of eif5a and its hypusine modification in eukaryotes
    • Park MH, Nishimura K, Zanelli CF, Valentini SR. Functional significance of eif5a and its hypusine modification in eukaryotes. Amino Acids 2010; 38:491-500.
    • (2010) Amino Acids , vol.38 , pp. 491-500
    • Park, M.H.1    Nishimura, K.2    Zanelli, C.F.3    Valentini, S.R.4
  • 24
    • 0027518126 scopus 로고
    • Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono- guanylated diamines and polyamines
    • Jakus J, Wolff EC, Park MH, Folk JE. Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines. J Biol Chem 1993; 268:13151-9. (Pubitemid 23307731)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.18 , pp. 13151-13159
    • Jakus, J.1    Wolff, E.C.2    Myung, H.P.3    Folk, J.E.4
  • 25
    • 3142543751 scopus 로고    scopus 로고
    • A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme. NAD. inhibitor ternary complex
    • DOI 10.1074/jbc.M404095200
    • Umland TC, Wolff EC, Park MH, Davies DR. A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme. NAD. Inhibitor ternary complex. J Biol Chem 2004; 279:28697-705. (Pubitemid 38900154)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 28697-28705
    • Umland, T.C.1    Wolff, E.C.2    Park, M.H.3    Davies, D.R.4
  • 26
    • 0036668578 scopus 로고    scopus 로고
    • 1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis
    • DOI 10.1023/A:1016535217038
    • Lee Y, Kim HK, Park HE, Park MH, Joe YA. Effect of n1-guanyl-1,7- diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis. Mol Cell Biochem 2002; 237:69-76. (Pubitemid 34965794)
    • (2002) Molecular and Cellular Biochemistry , vol.237 , Issue.1-2 , pp. 69-76
    • Lee, Y.1    Kim, H.-K.2    Park, H.-E.3    Park, M.H.4    Joe, Y.A.5
  • 28
    • 0027944561 scopus 로고
    • Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of chinese hamster ovary cells by guanyl diamines
    • Park MH, Wolff EC, Lee YB, Folk JE. Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of chinese hamster ovary cells by guanyl diamines. J Biol Chem 1994; 269:27827-32.
    • (1994) J Biol Chem , vol.269 , pp. 27827-27832
    • Park, M.H.1    Wolff, E.C.2    Lee, Y.B.3    Folk, J.E.4
  • 29
    • 33644830086 scopus 로고    scopus 로고
    • Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression
    • DOI 10.1007/s00438-005-0086-4
    • Chatterjee I, Gross SR, Kinzy TG, Chen KY. Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression. Mol Genet Genomics 2006; 275:264-76. (Pubitemid 43357663)
    • (2006) Molecular Genetics and Genomics , vol.275 , Issue.3 , pp. 264-276
    • Chatterjee, I.1    Gross, S.R.2    Kinzy, T.G.3    Chen, K.Y.4
  • 30
    • 33645129728 scopus 로고    scopus 로고
    • Pkc1 acts through zds1 and gic1 to suppress growth and cell polarity defects of a yeast eif5a mutant
    • Zanelli CF, Valentini SR. Pkc1 acts through zds1 and gic1 to suppress growth and cell polarity defects of a yeast eif5a mutant. Genetics 2005; 171:1571-81.
    • (2005) Genetics , vol.171 , pp. 1571-1581
    • Zanelli, C.F.1    Valentini, S.R.2
  • 31
    • 67649607136 scopus 로고    scopus 로고
    • The drosophila deoxyhypusine hydroxylase homologue nero and its target eif5a are required for cell growth and the regulation of autophagy
    • Patel PH, Costa-Mattioli M, Schulze KL, Bellen HJ. The drosophila deoxyhypusine hydroxylase homologue nero and its target eif5a are required for cell growth and the regulation of autophagy. J Cell Biol 2009; 185:1181-94.
    • (2009) J Cell Biol , vol.185 , pp. 1181-1194
    • Patel, P.H.1    Costa-Mattioli, M.2    Schulze, K.L.3    Bellen, H.J.4
  • 33
    • 54249154570 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 5A small interference rna-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury
    • Moore CC, Martin EN, Lee G, Taylor C, Dondero R, Reznikov LL, et al. Eukaryotic translation initiation factor 5A small interference rna-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury. J Infect Dis 2008; 198:1407-14.
    • (2008) J Infect Dis , vol.198 , pp. 1407-1414
    • Moore, C.C.1    Martin, E.N.2    Lee, G.3    Taylor, C.4    Dondero, R.5    Reznikov, L.L.6
  • 34
    • 0028852113 scopus 로고
    • Isolation and structural characterization of different isoforms of the hypusine-containing protein eif-5a from hela cells
    • Klier H, Csonga R, Joäo HC, Eckerskorn C, Auer M, Lottspeich F, et al. Isolation and structural characterization of different isoforms of the hypusine-containing protein eif-5a from hela cells. Biochemistry 1995; 34:14693-702.
    • (1995) Biochemistry , vol.34 , pp. 14693-14702
    • Klier, H.1    Csonga, R.2    Joäo, H.C.3    Eckerskorn, C.4    Auer, M.5    Lottspeich, F.6
  • 35
    • 0022521372 scopus 로고
    • Post-translational modification of the protein-synthesis initiation factor eIF-4D by spermidine in rat hepatoma cells
    • Gerner EW, Mamont PS, Bernhardt A, Siat M. Post- Translational modification of the protein-synthesis initiation factor eif-4d by spermidine in rat hepatoma cells. Biochem J 1986; 239:379-86. (Pubitemid 16008458)
    • (1986) Biochemical Journal , vol.239 , Issue.2 , pp. 379-386
    • Gerner, E.W.1    Mamont, P.S.2    Bernhardt, A.3    Siat, M.4
  • 36
    • 62149084863 scopus 로고    scopus 로고
    • Thermal killing of human colon cancer cells is associated with the loss of eukaryotic initiation factor 5A
    • Gosslau A, Jao DL, Butler R, Liu AY, Chen KY. Thermal killing of human colon cancer cells is associated with the loss of eukaryotic initiation factor 5A. J Cell Physiol 2009; 219:485-93.
    • (2009) J Cell Physiol , vol.219 , pp. 485-493
    • Gosslau, A.1    Jao, D.L.2    Butler, R.3    Liu, A.Y.4    Chen, K.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.